{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:15:52Z","timestamp":1776352552842,"version":"3.51.2"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,8,11]],"date-time":"2015-08-11T00:00:00Z","timestamp":1439251200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s10753-015-0226-x","type":"journal-article","created":{"date-parts":[[2015,8,10]],"date-time":"2015-08-10T06:05:32Z","timestamp":1439186732000},"page":"87-95","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Guggulsterone Attenuated Lipopolysaccharide-Induced Inflammatory Responses in Mouse Inner Medullary Collecting Duct-3 Cells"],"prefix":"10.1007","volume":"39","author":[{"given":"Dong-Goo","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gi-Sang","family":"Bae","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Il-Joo","family":"Jo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun-Bok","family":"Choi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myoung-Jin","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Hyeok","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae-Gil","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ho-Sub","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ho-Joon","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sung-Joo","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,8,11]]},"reference":[{"key":"226_CR1","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1172\/JCI114736","volume":"86","author":"RF Husted","year":"1990","unstructured":"Husted, R.F., J.R. Laplace, and J.B. Stokes. 1990. Enhancement of electrogenic Na+ transport across rat inner medullary collecting duct by glucocorticoid and by mineralocorticoid hormones. Journal of Clinical Investigation 86: 498\u2013506.","journal-title":"Journal of Clinical Investigation"},{"key":"226_CR2","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.1172\/JCI116003","volume":"90","author":"JR Laplace","year":"1992","unstructured":"Laplace, J.R., R.F. Husted, and J.B. Stokes. 1992. Cellular responses to steroids in the enhancement of Na+ transport by rat collecting duct cells in culture. Differences between glucocorticoid and mineralocorticoid hormones. Journal of Clinical Investigation 90: 1370\u20131378.","journal-title":"Journal of Clinical Investigation"},{"key":"226_CR3","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/BF00587019","volume":"308","author":"E Uhlich","year":"1969","unstructured":"Uhlich, E., C.A. Baldamus, and K.J. Ullrich. 1969. Effect of aldosterone on sodium transport in the collecting ducts of the mammalian kidney. Pfl\u00fcgers Archiv 308: 111\u2013126.","journal-title":"Pfl\u00fcgers Archiv"},{"key":"226_CR4","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1681\/ASN.2005040448","volume":"16","author":"M Vinciguerra","year":"2005","unstructured":"Vinciguerra, M., U. Hasler, D. Mordasini, M. Roussel, M. Capovilla, E. Ogier-Denis, A. Vandewalle, P.Y. Martin, and E. Feraille. 2005. Cytokines and sodium induce protein kinase A-dependent cell-surface Na, K-ATPase recruitment via dissociation of NF-kappaB\/IkappaB\/protein kinase A catalytic subunit complex in collecting duct principal cells. Journal of the American Society of Nephrology 16: 2576\u20132585.","journal-title":"Journal of the American Society of Nephrology"},{"key":"226_CR5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1369\/0022155411436131","volume":"60","author":"JY Choi","year":"2012","unstructured":"Choi, J.Y., S.A. Nam, D.C. Jin, J. Kim, and J.H. Cha. 2012. Expression and cellular localization of inducible nitric oxide synthase in lipopolysaccharide-treated rat kidneys. Journal of Histochemistry and Cytochemistry 60: 301\u2013315.","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"226_CR6","doi-asserted-by":"crossref","first-page":"F38","DOI":"10.1152\/ajprenal.00590.2010","volume":"302","author":"C K\u00fcper","year":"2012","unstructured":"K\u00fcper, C., F.X. Beck, and W. Neuhofer. 2012. Toll-like receptor 4 activates NF-\u03baB and MAP kinase pathways to regulate expression of proinflammatory COX-2 in renal medullary collecting duct cells. American Journal of Physiology. Renal Physiology 302: F38\u201346.","journal-title":"American Journal of Physiology. Renal Physiology"},{"key":"226_CR7","doi-asserted-by":"crossref","first-page":"4773","DOI":"10.4049\/jimmunol.177.7.4773","volume":"177","author":"C Chassin","year":"2006","unstructured":"Chassin, C., J.M. Goujon, S. Darche, L. du Merle, M. Bens, F. Cluzeaud, C. Werts, E. Ogier-Denis, C. Le Bougu\u00e9nec, D. Buzoni-Gatel, and A. Vandewalle. 2006. Renal collecting duct epithelial cells react to pyelonephritis-associated Escherichia coli by activating distinct TLR4-dependent and -independent inflammatory pathways. Journal of Immunology 177: 4773\u20134784.","journal-title":"Journal of Immunology"},{"key":"226_CR8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S1043-2760(02)00640-9","volume":"13","author":"CJ Sinal","year":"2002","unstructured":"Sinal, C.J., and F.J. Gonzalez. 2002. Guggulsterone: an old approach to a new problem. Trends in Endocrinology and Metabolism 13: 275\u20136.","journal-title":"Trends in Endocrinology and Metabolism"},{"key":"226_CR9","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1146\/annurev.nutr.23.011702.073102","volume":"23","author":"NL Urizar","year":"2003","unstructured":"Urizar, N.L., and D.D. Moore. 2003. GUGULIPID: a natural cholesterol-lowering agent. Annual Review of Nutrition 23: 303\u201313.","journal-title":"Annual Review of Nutrition"},{"key":"226_CR10","first-page":"278718","volume":"2012","author":"MS Kim","year":"2012","unstructured":"Kim, M.S., G.S. Bae, K.C. Park, B.S. Koo, B.J. Kim, H.J. Lee, S.W. Seo, Y.K. Shin, W.S. Jung, J.H. Cho, Y.C. Kim, T.H. Kim, H.J. Song, and S.J. Park. 2012. Myrrh inhibits LPS-induced inflammatory response and protects from cecal ligation and puncture-induced sepsis. Evidence-based Complementary and Alternative Medicine 2012: 278718.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"226_CR11","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.intimp.2015.03.030","volume":"26","author":"DG Kim","year":"2015","unstructured":"Kim, D.G., G.S. Bae, S.B. Choi, I.J. Jo, J.Y. Shin, S.K. Lee, M.J. Kim, M.J. Kim, H.W. Jeong, C.M. Choi, S.H. Seo, G.C. Choo, S.W. Seo, H.J. Song, and S.J. Park. 2015. Guggulsterone attenuates cerulein-induced acute pancreatitis via inhibition of ERK and JNK activation. International Immunopharmacology 26: 194\u2013202.","journal-title":"International Immunopharmacology"},{"key":"226_CR12","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3810\/pgm.2014.01.2722","volume":"126","author":"PC Deedwania","year":"2014","unstructured":"Deedwania, P.C. 2014. Statins in chronic kidney disease: cardiovascular risk and kidney function. Postgraduate Medicine 126: 29\u201336.","journal-title":"Postgraduate Medicine"},{"key":"226_CR13","doi-asserted-by":"crossref","unstructured":"Sim\u00f5es e Silva, A.C., F.C. Val\u00e9rio, M.A. Vasconcelos, D.M. Miranda, E.A. Oliveira. 2013. Interactions between cytokines, congenital anomalies of kidney and urinary tract and chronic kidney disease. Clinical Developmental Immunology 2013: 597920.","DOI":"10.1155\/2013\/597920"},{"key":"226_CR14","doi-asserted-by":"crossref","first-page":"R659","DOI":"10.1152\/ajpregu.00345.2013","volume":"305","author":"DE Kohan","year":"2013","unstructured":"Kohan, D.E. 2013. Role of collecting duct endothelin in control of renal function and blood pressure. American Journal of Physiology Regulatory Integr Comparative Physiology 305: R659\u2013668.","journal-title":"American Journal of Physiology Regulatory Integr Comparative Physiology"},{"key":"226_CR15","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1681\/ASN.2012111112","volume":"24","author":"M Sedeek","year":"2013","unstructured":"Sedeek, M., R. Nasrallah, R.M. Touyz, and R.L. H\u00e9bert. 2013. NADPH oxidases, reactive oxygen species, and the kidney: friend and foe. Journal of the American Society of Nephrology 24: 1512\u20131518.","journal-title":"Journal of the American Society of Nephrology"},{"key":"226_CR16","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1681\/ASN.2010080798","volume":"22","author":"HJ Anders","year":"2011","unstructured":"Anders, H.J., and D.A. Muruve. 2011. The inflammasomes in kidney disease. Journal of American Society of Nephrology 22: 1007\u20131018.","journal-title":"Journal of American Society of Nephrology"},{"key":"226_CR17","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1126\/science.282.5396.2085","volume":"282","author":"A Poltorak","year":"1998","unstructured":"Poltorak, A., X. He, I. Smirnova, M.Y. Liu, C. Van Huffel, X. Du, D. Birdwell, E. Alejos, M. Silva, C. Galanos, M. Freudenberg, P. Ricciardi-Castagnoli, B. Layton, and B. Beutler. 1998. Defective LPS signaling in C3H\/HeJ and C57BL\/10ScCr mice:mutations in Tlr4 gene. Science 282: 2085\u20132088.","journal-title":"Science"},{"key":"226_CR18","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/nature01326","volume":"420","author":"J Cohen","year":"2002","unstructured":"Cohen, J. 2002. The immunopathogenesis of sepsis. Nature 420: 885\u2013891.","journal-title":"Nature"},{"key":"226_CR19","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1681\/ASN.2007121273","volume":"19","author":"C Chassin","year":"2008","unstructured":"Chassin, C., S. Vimont, F. Cluzeaud, M. Bens, J.M. Goujon, B. Fernandez, A. Hertig, E. Rondeau, G. Arlet, M.W. Hornef, and A. Vandewalle. 2008. TLR4 facilitates translocation of bacteria across renal collecting duct cells. Journal of the American Society of Nephrology 19: 2364\u20132374.","journal-title":"Journal of the American Society of Nephrology"},{"key":"226_CR20","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.coph.2013.04.008","volume":"13","author":"RT Akasheh","year":"2013","unstructured":"Akasheh, R.T., J. Pang, J.M. York, and G. Fantuzzi. 2013. New pathways to control inflammatory responses in adipose tissue. Current Opinion in Pharmacology 13: 613\u2013617.","journal-title":"Current Opinion in Pharmacology"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-015-0226-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-015-0226-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-015-0226-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,30]],"date-time":"2019-05-30T23:42:44Z","timestamp":1559259764000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-015-0226-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8,11]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["226"],"URL":"https:\/\/doi.org\/10.1007\/s10753-015-0226-x","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,8,11]]}}}