{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T06:51:28Z","timestamp":1770274288318,"version":"3.49.0"},"reference-count":59,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,11,12]],"date-time":"2016-11-12T00:00:00Z","timestamp":1478908800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s10753-016-0471-7","type":"journal-article","created":{"date-parts":[[2016,11,12]],"date-time":"2016-11-12T05:01:20Z","timestamp":1478926880000},"page":"205-220","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Protective Effect of Crocodile Hemoglobin and Whole Blood Against Hydrogen Peroxide-Induced Oxidative Damage in Human Lung Fibroblasts (MRC-5) and Inflammation in Mice"],"prefix":"10.1007","volume":"40","author":[{"given":"Santi","family":"Phosri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nisachon","family":"Jangpromma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rina","family":"Patramanon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bunkerd","family":"Kongyingyoes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pramote","family":"Mahakunakorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sompong","family":"Klaynongsruang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,11,12]]},"reference":[{"key":"471_CR1","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1016\/j.lfs.2003.09.047","volume":"74","author":"Y Cai","year":"2004","unstructured":"Cai, Y., Q. Luo, M. Sun, and H. Corke. 2004. Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sciences 74: 2157\u20132184.","journal-title":"Life Sciences"},{"key":"471_CR2","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1016\/j.jep.2011.07.041","volume":"137","author":"JS Deng","year":"2011","unstructured":"Deng, J.S., C.S. Chi, S.S. Huang, P.H. Shie, T.H. Lin, and G.J. Huang. 2011. Antioxidant, analgesic, and anti-inflammatory activities of the ethanolic extracts of Taxillus liquidambaricola. Journal of Ethnopharmacology 137: 1161\u20131171.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR3","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.jep.2011.07.048","volume":"137","author":"T Yu","year":"2011","unstructured":"Yu, T., H.M. Ahn, T. Shen, K. Yoon, H.J. Jang, Y.J. Lee, et al. 2011. Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans. Journal of Ethnopharmacology 137: 1197\u20131206.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR4","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0014-2999(96)00140-9","volume":"303","author":"D Salvemini","year":"1966","unstructured":"Salvemini, D., Z.Q. Wang, D.M. Bourdon, M.K. Stern, M.G. Currie, and P.T. Manning. 1966. Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. European Journal of Pharmacology 303: 217\u2013220.","journal-title":"European Journal of Pharmacology"},{"key":"471_CR5","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.foodres.2015.01.032","volume":"70","author":"C Calloni","year":"2015","unstructured":"Calloni, C., R.D. Agnol, L.S. Martinez, F.D.S. Marcon, S. Moura, and M. Salvador. 2015. Jaboticaba (Plinia trunciflora (O. Berg) Kausel) fruit reduces oxidative stress in human fibroblasts cells (MRC-5). Food Research International 70: 15\u201322.","journal-title":"Food Research International"},{"key":"471_CR6","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.jep.2007.07.017","volume":"113","author":"F Naaz","year":"2007","unstructured":"Naaz, F., S. Javed, and M.Z. Abdin. 2007. Hepatoprotective effect of ethanolic extract of Phyllanthus amarus Schum. et Thonn. on aflatoxinB1-induced liver damage in mice. Journal of Ethnopharmacology 113: 503\u2013509.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR7","doi-asserted-by":"crossref","first-page":"9252","DOI":"10.3390\/molecules15129252","volume":"15","author":"MG Miguel","year":"2010","unstructured":"Miguel, M.G. 2010. Antioxidant and anti-inflammatory activities of essential oils: a short review. Molecules 15: 9252\u20139287.","journal-title":"Molecules"},{"key":"471_CR8","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/j.jep.2013.03.025","volume":"147","author":"SS Huang","year":"2013","unstructured":"Huang, S.S., C.S. Chiu, T.H. Lin, M.M. Lee, C.Y. Lee, S.J. Chang, et al. 2013. Antioxidant and anti-inflammatory activities of aqueous extract of Centipeda minima. Journal of Ethnopharmacology 147: 395\u2013405.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR9","first-page":"3121","volume":"7","author":"S Preecharram","year":"2008","unstructured":"Preecharram, S., S. Daduang, W. Bunyatratchata, T. Araki, and S. Thammasirirak. 2008. Antibacterial activity from Siamese crocodile (Crocodylus siamensis) serum. African Journal of Biotechnology 7: 3121\u20133128.","journal-title":"African Journal of Biotechnology"},{"key":"471_CR10","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.1740-0929.2010.00752.x","volume":"81","author":"S Preecharram","year":"2010","unstructured":"Preecharram, S., P. Jearranaiprepame, S. Daduang, Y. Temsiripong, T. Somdee, T. Fukamizo, et al. 2010. Isolation and characterisation of crocosin, an antibacterial compound from crocodile (Crocodylus siamensis) plasma. Animal Science Journal 81: 393\u2013401.","journal-title":"Animal Science Journal"},{"key":"471_CR11","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.dci.2010.12.011","volume":"35","author":"S Pata","year":"2011","unstructured":"Pata, S., N. Yaraksa, S. Daduang, Y. Temsiripong, J. Svasti, T. Araki, et al. 2011. Characterization of the novel antibacterial peptide Leucrocin from crocodile (Crocodylus siamensis) white blood cell extracts. Developmental & Comparative Immunology 35: 545\u2013553.","journal-title":"Developmental & Comparative Immunology"},{"key":"471_CR12","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1007\/s10930-012-9424-7","volume":"31","author":"S Srihongthong","year":"2012","unstructured":"Srihongthong, S., A. Pakdeesuwan, S. Daduang, T. Araki, A. Dhiravisit, and S. Thammasirirak. 2012. Complete amino acid sequence of globin chains and biological activity of fragmented crocodile hemoglobin (Crocodylus siamensis). The Protein Journal 31: 466\u2013476.","journal-title":"The Protein Journal"},{"key":"471_CR13","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1476-0711-11-22","volume":"11","author":"J Kommanee","year":"2012","unstructured":"Kommanee, J., S. Preecharram, S. Daduang, T. Yosapong, A. Dhiravisit, Y. Yuzo, et al. 2012. Antibacterial activity of plasma from crocodile (Crocodylus siamensis) against pathogenic bacteria. Annals Clinical Microbiology and Antimicrobial 11: 22.","journal-title":"Annals Clinical Microbiology and Antimicrobial"},{"key":"471_CR14","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/ja.2013.114","volume":"67","author":"N Yaraksa","year":"2014","unstructured":"Yaraksa, N., T. Anunthawan, T. Theansungnoen, S. Daduang, T. Araki, A. Dhiravisit, et al. 2014. Design and synthesis of cationic antibacterial peptide based on Leucrocin I sequence, antibacterial peptide from crocodile (Crocodylus siamensis) white blood cell extracts. The Journal of Antibiotics 67: 205\u2013212.","journal-title":"The Journal of Antibiotics"},{"key":"471_CR15","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s10930-011-9372-7","volume":"31","author":"J Jandaruang","year":"2012","unstructured":"Jandaruang, J., J. Siritapetawee, K. Thumanu, C. Songsiriritthigul, C. Krittanai, S. Daduang, et al. 2012. The effects of temperature and pH on secondary structure and antioxidant activity of Crocodylus siamensis hemoglobin. The Protein Journal 31: 43\u201350.","journal-title":"The Protein Journal"},{"key":"471_CR16","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s10930-013-9536-8","volume":"33","author":"T Theansungnoen","year":"2014","unstructured":"Theansungnoen, T., N. Yaraksa, S. Daduang, A. Dhiravisit, and S. Thammasirirak. 2014. Purification and characterization of antioxidant peptides from leukocyte extract of Crocodylus siamensis. The Protein Journal 33: 24\u201331.","journal-title":"The Protein Journal"},{"key":"471_CR17","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1007\/s10930-014-9581-y","volume":"33","author":"S Phosri","year":"2014","unstructured":"Phosri, S., P. Mahakunakorn, J. Lueangsakulthai, N. Jangpromma, P. Swatsitang, S. Daduang, et al. 2014. An investigation of antioxidant and anti-inflammatory activities from blood components of crocodile (Crocodilus siamensis). The Protein Journal 33: 484\u2013492.","journal-title":"The Protein Journal"},{"key":"471_CR18","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1038\/nprot.2006.179","volume":"1","author":"V Vichai","year":"2006","unstructured":"Vichai, V., and K. Kirtikara. 2006. Sulforhodamine B colorimetric assay for cytotoxicity screening. Nature Protocols 1: 1112\u20131116.","journal-title":"Nature Protocols"},{"key":"471_CR19","doi-asserted-by":"crossref","first-page":"544","DOI":"10.3181\/00379727-111-27849","volume":"111","author":"CA Winter","year":"1962","unstructured":"Winter, C.A., E.A. Risley, and G.W. Nuss. 1962. Carrageenin-induced edema in hind paw of the rat as an assay for antiinflammatory drugs. Proceedings of the Society for Experimental Biology and Medicine 111: 544\u2013547.","journal-title":"Proceedings of the Society for Experimental Biology and Medicine"},{"key":"471_CR20","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/jps.3030460902","volume":"46","author":"CA Winter","year":"1957","unstructured":"Winter, C.A., and C.C. Porter. 1957. Effect of alteration in side chains upon anti-inflammatory and liver glycogen activities in hydrocortisone esters. Journal of the American Pharmacists Association 46: 515\u2013519.","journal-title":"Journal of the American Pharmacists Association"},{"key":"471_CR21","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72: 248\u2013254.","journal-title":"Analytical Biochemistry"},{"key":"471_CR22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/0009-8981(91)90067-M","volume":"196","author":"L Goth","year":"1991","unstructured":"Goth, L. 1991. A simple method for determination of serum catalase activity, and revision of reference range. Clinica Chimica Acta 196: 143\u2013152.","journal-title":"Clinica Chimica Acta"},{"key":"471_CR23","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/clinchem\/34.3.497","volume":"34","author":"Y Sun","year":"1988","unstructured":"Sun, Y., L.W. Oberley, and Y. Li. 1988. A simple method for clinical assay of superoxide dismutase. Clinical Chemistry 34: 497\u2013500.","journal-title":"Clinical Chemistry"},{"key":"471_CR24","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1111\/jphp.12003","volume":"65","author":"W Chatuphonprasert","year":"2013","unstructured":"Chatuphonprasert, W., L. Udomsuk, O. Monthakantirat, Y. Churikhit, W. Putalun, and K. Jarukamjorn. 2013. Effects of Pueraria mirifica and miroestrol on the antioxidation-related enzymes in ovariectomized mice. Journal of Pharmacy and Pharmacology 65: 447\u2013456.","journal-title":"Journal of Pharmacy and Pharmacology"},{"key":"471_CR25","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1042\/bj1120109","volume":"112","author":"RE Pinto","year":"1969","unstructured":"Pinto, R.E., and W. Bartley. 1969. The effect of age and sex on glutathione reductase and glutathione peroxidase activities and on aerobic glutathione oxidation in rat liver homogenates. Biochemical Journal 112: 109\u2013115.","journal-title":"Biochemical Journal"},{"key":"471_CR26","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa, H., N. Ohishi, and K. Yagi. 1979. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry 95: 351\u2013358.","journal-title":"Analytical Biochemistry"},{"key":"471_CR27","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.foodchem.2012.04.122","volume":"135","author":"B Kong","year":"2012","unstructured":"Kong, B., X. Peng, Y.L. Xiong, and X. Zhao. 2012. Protection of lung fibroblast MRC-5 cells against hydrogen peroxide-induced oxidative damage by 0.1\u20132.8 kDa antioxidative peptides isolated from whey protein hydrolysate. Food Chemistry 135: 540\u2013547.","journal-title":"Food Chemistry"},{"key":"471_CR28","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.jff.2014.09.011","volume":"11","author":"N Jia","year":"2014","unstructured":"Jia, N., T. Li, X. Diao, and B. Kong. 2014. Protective effects of black currant (Ribesnigrum L.) extract on hydrogen peroxide-induced damage in lung fibroblast MRC-5 cells in relation to the antioxidant activity. Journal of Functional Foods 11: 142\u2013151.","journal-title":"Journal of Functional Foods"},{"key":"471_CR29","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1172\/JCI113230","volume":"80","author":"CC Winterbourn","year":"1987","unstructured":"Winterbourn, C.C., and A. Stern. 1987. Human red cells scavenge extracellular hydrogen peroxide and inhibit formation of hypochlorous acid and hydroxyl radical. The Journal of Clinical Investigation 80: 1486\u20131491.","journal-title":"The Journal of Clinical Investigation"},{"key":"471_CR30","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/j.jep.2009.02.041","volume":"125","author":"NP Babu","year":"2009","unstructured":"Babu, N.P., P. Pandikumar, and S. Ignacimuthu. 2009. Anti-inflammatory activity of Albizia lebbeck Benth., an ethnomedicinal plant, in acute and chronic animal models of inflammation. Journal of Ethnopharmacology 125: 356\u2013360.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR31","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.pbb.2014.05.004","volume":"124","author":"W Boonyarikpunchai","year":"2014","unstructured":"Boonyarikpunchai, W., S. Sukrong, and P. Towiwat. 2014. Antinociceptive and anti-inflammatory effects of rosmarinic acid isolated from Thunbergia laurifolia Lindl. Pharmacology, Biochemistry and Behavior 124: 67\u201373.","journal-title":"Pharmacology, Biochemistry and Behavior"},{"key":"471_CR32","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/clim.1999.4696","volume":"91","author":"DL Lefkowitz","year":"1999","unstructured":"Lefkowitz, D.L., M.P. Gelderman, S.R. Fuhrmann, S. Graham, J.D. Starnes, S.S. Lefkowitz, et al. 1999. Neutrophilic lysozyme-macrophage interactions perpetuate chronic inflammation associated with experimental arthritis. Clinical Immunology 91: 145\u2013155.","journal-title":"Clinical Immunology"},{"key":"471_CR33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.biomag.2011.11.001","volume":"2","author":"SL Badole","year":"2012","unstructured":"Badole, S.L., A.A. Zanwar, A.E. Ghule, P. Ghosh, and S.L. Bodhankar. 2012. Analgesic and anti-inflammatory activity of alcoholic extract of stem bark of Pongamia pinnata (L.) Pierre. Biomedicine & Aging Pathology 2: 19\u201323.","journal-title":"Biomedicine & Aging Pathology"},{"key":"471_CR34","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1055\/s-0033-1351018","volume":"79","author":"JS Da Rosa","year":"2013","unstructured":"Da Rosa, J.S., B.M. Facchin, J. Bastos, M.A. Siqueira, G.A. Micke, E.M. Dalmarco, et al. 2013. Systemic administration of Rosmarinus officinalis attenuates the inflammatory response induced by carrageenan in the mouse model of pleurisy. Planta Medica 79: 1605\u20131614.","journal-title":"Planta Medica"},{"key":"471_CR35","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1161\/01.CIR.87.1.80","volume":"87","author":"P Collins","year":"1993","unstructured":"Collins, P., J. Burman, H.I. Chung, and K. Fox. 1993. Hemoglobin inhibits endothelium-dependent relaxation to acetylcholine in human coronary arteries in vivo. Circulation 87: 80\u201385.","journal-title":"Circulation"},{"key":"471_CR36","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1097\/00004647-199809000-00007","volume":"18","author":"JP Dreier","year":"1998","unstructured":"Dreier, J.P., K. Korner, N. Ebert, A. Gorner, I. Rubin, T. Back, et al. 1998. Nitric oxide scavenging by hemoglobin or nitric oxide synthase inhibition by N-nitro-L-arginine induce cortical spreading ischemia when K+ is increased in the subarachnoid space. Journal of Cerebral Blood Flow & Metabolism 18: 978\u2013990.","journal-title":"Journal of Cerebral Blood Flow & Metabolism"},{"key":"471_CR37","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1113\/jphysiol.1957.sp005777","volume":"136","author":"QH Gibson","year":"1957","unstructured":"Gibson, Q.H., and F.J.W. Roughton. 1957. The kinetics and equilibria of the reactions of nitric oxide with sheep haemoglobin. The Journal of Physiology 136: 507\u2013526.","journal-title":"The Journal of Physiology"},{"key":"471_CR38","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0891-5849(98)00192-0","volume":"26","author":"A Niess","year":"1999","unstructured":"Niess, A., F. Passek, I. Lorenz, E. Schneider, H. Dickhuth, H. Northoff, et al. 1999. Expression of the antioxidant stress protein heme oxygenase-1 (HO-1) in human leukocytes. Free Radical Biology and Medicine 26: 184\u2013192.","journal-title":"Free Radical Biology and Medicine"},{"key":"471_CR39","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nm0302-240","volume":"8","author":"TS Lee","year":"2002","unstructured":"Lee, T.S., and L.Y. Chau. 2002. Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice. Nature Medicine 8: 240\u2013246.","journal-title":"Nature Medicine"},{"key":"471_CR40","doi-asserted-by":"crossref","first-page":"416","DOI":"10.3923\/ajb.2011.416.425","volume":"6","author":"K Sathyapriya","year":"2011","unstructured":"Sathyapriya, K., and C.S. Parameswari. 2011. Effect of dialysis on heme oxygenase-1 (HO-1) expression in peripheral blood leukocytes of end staged renal diseased patients. Asian Journal of Biochemistry 6: 416\u2013425.","journal-title":"Asian Journal of Biochemistry"},{"key":"471_CR41","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1152\/physrev.00011.2005","volume":"86","author":"SW Ryter","year":"2006","unstructured":"Ryter, S.W., J. Alam, and A.M. Choi. 2006. Heme oxygenase-1\/carbon monoxide: from basic science to therapeutic applications. Physiological Reviews 86: 583\u2013650.","journal-title":"Physiological Reviews"},{"key":"471_CR42","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1152\/ajpgi.00231.2010","volume":"300","author":"A Habtezion","year":"2011","unstructured":"Habtezion, A., R. Kwan, A.L. Yang, M.E. Morgan, E. Akhtar, S.P. Wanaski, et al. 2011. Heme oxygenase-1 is induced in peripheral blood mononuclear cells of patients with acute pancreatitis: a potential therapeutic target. American Journal of Physiology-Gastrointestinal and Liver Physiology 300: 12\u201320.","journal-title":"American Journal of Physiology-Gastrointestinal and Liver Physiology"},{"key":"471_CR43","first-page":"308","volume":"5","author":"LNF Darville","year":"2010","unstructured":"Darville, L.N.F., M.E. Merchant, A. Hasan, and K.K. Murray. 2010. Proteome analysis of the leukocytes from the American alligator (Alligator mississippiensis) using mass spectrometry. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics 5: 308\u2013316.","journal-title":"Comparative Biochemistry and Physiology Part D: Genomics and Proteomics"},{"key":"471_CR44","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1007\/s00281-011-0284-6","volume":"34","author":"CT Esmon","year":"2012","unstructured":"Esmon, C.T. 2012. Protein C anticoagulant system\u2014anti-inflammatory effects. Seminars in Immunopathology 34: 127\u2013132.","journal-title":"Seminars in Immunopathology"},{"key":"471_CR45","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.intimp.2013.10.013","volume":"17","author":"YX Zang","year":"2013","unstructured":"Zang, Y.X., L. Wang, E.L. Xiao, S.J. Li, J.J. Chen, B. Gao, et al. 2013. Ginsenoside-Rd exhibits anti-inflammatory activities through elevation of antioxidant enzyme activities and inhibition of JNK and ERK activation in vivo. International Immunopharmacology 17: 1094\u20131100.","journal-title":"International Immunopharmacology"},{"key":"471_CR46","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.phymed.2013.09.022","volume":"21","author":"Y Gao","year":"2013","unstructured":"Gao, Y., L. Fang, R. Cai, C. Zong, X. Chen, J. Lu, et al. 2013. Shuang-Huang-Lian exerts anti-inflammatory and anti-oxidative activities in lipopolysaccharide-stimulated murine alveolar macrophages. Phytomedicine 21: 461\u2013469.","journal-title":"Phytomedicine"},{"key":"471_CR47","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1177\/147323000303100207","volume":"31","author":"E Kirimi","year":"2003","unstructured":"Kirimi, E., O. Tuncer, M. Kosem, E. Ceylan, A. Tas, I. Tasal, et al. 2003. The effects of prednisolone and serum malondialdehyde levels in puppies with experimentally induced meconium aspiration syndrome. Journal of International Medical Research 31: 113\u2013122.","journal-title":"Journal of International Medical Research"},{"key":"471_CR48","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.jep.2014.10.060","volume":"162","author":"P Pingsusaen","year":"2015","unstructured":"Pingsusaen, P., P. Kunanusorn, P. Khonsung, N. Chiranthanut, A. Panthong, and C. Rujjanawate. 2015. Investigation of anti-inflammatory, antinociceptive and antipyretic activities of Stahlianthus involucratus rhizome ethanol extract. Journal of Ethnopharmacology 162: 199\u2013206.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR49","doi-asserted-by":"crossref","first-page":"9748","DOI":"10.1073\/pnas.85.24.9748","volume":"85","author":"B Frei","year":"1988","unstructured":"Frei, B., R. Stocker, and B.N. Ames. 1988. Antioxidant defenses and lipid peroxidation in human blood plasma. Proceedings of the National Academy of Sciences of the United States of America 85: 9748\u20139752.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"471_CR50","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1016\/j.ecoenv.2008.02.022","volume":"71","author":"M Yu","year":"2008","unstructured":"Yu, M., S.M. Li, X.Y. Li, B.J. Zhang, and J.J. Wang. 2008. Acute effects of 1-octyl-3-methylimidazolium bromide ionic liquid on the antioxidant enzyme system of mouse liver. Ecotoxicology and Environmental Safety 71: 903\u2013908.","journal-title":"Ecotoxicology and Environmental Safety"},{"key":"471_CR51","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.jep.2004.11.026","volume":"97","author":"HJ Jung","year":"2005","unstructured":"Jung, H.J., J.H. Nam, J. Choi, K.T. Lee, and H.J. Park. 2005. Anti-inflammatory effects of chiisanoside and chiisanogenin obtained from the leaves of Acanthopanax chiisanensis in the carrageenan and Freund\u2019s complete adjuvant-induced rats. Journal of Ethnopharmacology 97: 359\u2013367.","journal-title":"Journal of Ethnopharmacology"},{"key":"471_CR52","doi-asserted-by":"crossref","first-page":"438912","DOI":"10.1155\/2012\/438912","volume":"2012","author":"H Uzkeser","year":"2012","unstructured":"Uzkeser, H., E. Cadirci, Z. Halici, F. Odabasoglu, B. Polat, T.N. Yuksel, et al. 2012. Anti-inflammatory and antinociceptive effects of salbutamolon acute and chronic models of inflammation in rats:involvement of an antioxidant mechanism. Mediators of Inflammation 2012: 438912.","journal-title":"Mediators of Inflammation"},{"key":"471_CR53","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.freeradbiomed.2012.11.003","volume":"55","author":"DA Vitturi","year":"2013","unstructured":"Vitturi, D.A., C.W. Sun, V.M. Harper, B. Thrash-Williams, N. Cantu-Medellin, B.K. Chacko, et al. 2013. Antioxidant functions for the hemoglobin \u03b293 cysteine residue in erythrocytes and in the vascular compartment in vivo. Free Radical Biology and Medicine 55: 119\u2013129.","journal-title":"Free Radical Biology and Medicine"},{"key":"471_CR54","first-page":"2","volume":"8","author":"M Prakash","year":"2009","unstructured":"Prakash, M., M.S. Shetty, P. Tilak, and N. Anwar. 2009. Total thiols: biomedical importance and their alteration in various disorders. Online Journal of Health and Allied Science 8: 2.","journal-title":"Online Journal of Health and Allied Science"},{"key":"471_CR55","first-page":"225","volume":"57","author":"J Chakrabarty","year":"2013","unstructured":"Chakrabarty, J., M.S. Vidyasagar, D. Fernandes, V. Bhat, J.G. Nagalakshmi, and S.S. Mayya. 2013. Effectiveness of pranayama on the levels of serum protein thiols and glutathione in breast cancer patients undergoing radiation therapy: a randomized controlled trial. Indian Journal of Physiology and Pharmacology 57: 225\u2013232.","journal-title":"Indian Journal of Physiology and Pharmacology"},{"key":"471_CR56","first-page":"22","volume":"146","author":"E Reischl","year":"2007","unstructured":"Reischl, E., A.L. Dafre, J.L. Franco, and F.D. Wilhelm. 2007. Distribution, adaptation and physiological meaning of thiols from vertebrate hemoglobins. Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 146: 22\u201353.","journal-title":"Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology"},{"key":"471_CR57","doi-asserted-by":"crossref","first-page":"8151","DOI":"10.1021\/jf040266f","volume":"52","author":"O Demirkol","year":"2004","unstructured":"Demirkol, O., C. Adams, and N. Ercal. 2004. Biologically important thiols in various vegetables and fruits. Journal of Agricultural and Food Chemistry 52: 8151\u20138154.","journal-title":"Journal of Agricultural and Food Chemistry"},{"key":"471_CR58","doi-asserted-by":"crossref","first-page":"3148","DOI":"10.3390\/ijms12053148","volume":"12","author":"CC Udenigwe","year":"2011","unstructured":"Udenigwe, C.C., and R.E. Aluko. 2011. Chemometric analysis of the amino acid requirements of antioxidant food protein hydrolysates. International Journal of Molecular Sciences 12: 3148\u20133161.","journal-title":"International Journal of Molecular Sciences"},{"key":"471_CR59","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/2110-5820-3-4","volume":"3","author":"M Taverna","year":"2013","unstructured":"Taverna, M., A.L. Marie, J.P. Mira, and B. Guidet. 2013. Specific antioxidant properties of human serum albumin. Annals of Intensive Care 3: 4.","journal-title":"Annals of Intensive Care"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-016-0471-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-016-0471-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-016-0471-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T08:05:41Z","timestamp":1601193941000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-016-0471-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,12]]},"references-count":59,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["471"],"URL":"https:\/\/doi.org\/10.1007\/s10753-016-0471-7","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,11,12]]}}}