{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T16:01:14Z","timestamp":1762272074012,"version":"3.37.3"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T00:00:00Z","timestamp":1480291200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100003970","name":"Isfahan University of Medical Sciences","doi-asserted-by":"publisher","award":["393816"],"award-info":[{"award-number":["393816"]}],"id":[{"id":"10.13039\/501100003970","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s10753-016-0476-2","type":"journal-article","created":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T06:22:24Z","timestamp":1480314144000},"page":"259-274","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Immunomodulatory Effects of Adjuvants CPG, MPLA, and BCG on the Derp2-Induced Acute Asthma at Early Life in an Animal Model of BALB\/c Mice"],"prefix":"10.1007","volume":"40","author":[{"given":"V.","family":"Mohammadi-Shahrokhi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rezaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Andalib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rahnama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Jafarzadeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Eskandari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,11,28]]},"reference":[{"key":"476_CR1","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1038\/nri1934","volume":"6","author":"M Larche","year":"2006","unstructured":"Larche, M., C.A. Akdis, and R. Valenta. 2006. Immunological mechanisms of allergen-specific immunotherapy. Nature Reviews. Immunology 6: 761\u2013771.","journal-title":"Nature Reviews. Immunology"},{"key":"476_CR2","first-page":"9868704","volume":"2016","author":"L Zhang","year":"2016","unstructured":"Zhang, L., L. He, J. Gong, and C. Liu. 2016. Risk factors associated with irreversible airway obstruction in asthma: a systematic review and meta-analysis. BioMed Research International 2016: 9868704.","journal-title":"BioMed Research International"},{"key":"476_CR3","doi-asserted-by":"crossref","first-page":"877","DOI":"10.3349\/ymj.2015.56.4.877","volume":"56","author":"JU Lee","year":"2015","unstructured":"Lee, J.U., J.D. Kim, and C.S. Park. 2015. Gene-environment interactions in asthma: genetic and epigenetic effects. Yonsei Medical Journal 56: 877\u2013886.","journal-title":"Yonsei Medical Journal"},{"key":"476_CR4","first-page":"287","volume":"28","author":"X Wang","year":"2010","unstructured":"Wang, X., Q. Yang, P. Wang, et al. 2010. Derp2-mutant gene vaccine inhibits airway inflammation and up-regulates Toll-like receptor 9 in an allergic asthmatic mouse model. Asian Pacific Journal of Allergy and Immunology\/Launched by the Allergy and Immunology Society of Thailand 28: 287\u2013293.","journal-title":"Asian Pacific Journal of Allergy and Immunology\/Launched by the Allergy and Immunology Society of Thailand"},{"key":"476_CR5","doi-asserted-by":"crossref","first-page":"569","DOI":"10.3109\/02770903.2012.695418","volume":"49","author":"S Genc","year":"2012","unstructured":"Genc, S., H. Eroglu, U.C. Kucuksezer, et al. 2012. The decreased CD4+CD25+ FoxP3+ T cells in nonstimulated allergic rhinitis patients sensitized to house dust mites. The Journal of Asthma: Official Journal of the Association for the Care of Asthma 49: 569\u2013574.","journal-title":"The Journal of Asthma: Official Journal of the Association for the Care of Asthma"},{"key":"476_CR6","doi-asserted-by":"crossref","unstructured":"Tong P, Wesemann DR. 2015. Molecular mechanisms of IgE class switch recombination. In IgE antibodies: generation and function. Berlin: Springer, pp 21\u201337.","DOI":"10.1007\/978-3-319-13725-4_2"},{"key":"476_CR7","doi-asserted-by":"crossref","first-page":"S80","DOI":"10.1097\/00005344-199500252-00017","volume":"25","author":"J Bienvenu","year":"1995","unstructured":"Bienvenu, J., C. Doche, M.C. Gutowski, et al. 1995. Production of proinflammatory cytokines and cytokines involved in the TH1\/TH2 balance is modulated by pentoxifylline. Journal of Cardiovascular Pharmacology 25: S80\u2013S84.","journal-title":"Journal of Cardiovascular Pharmacology"},{"key":"476_CR8","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1365-2249.2009.04014.x","volume":"158","author":"C Bisseye","year":"2009","unstructured":"Bisseye, C., M. van der Sande, W.D. Morgan, et al. 2009. Plasmodium falciparum infection of the placenta impacts on the T helper type 1 (Th1)\/Th2 balance of neonatal T cells through CD4(+)CD25(+) forkhead box P3(+) regulatory T cells and interleukin-10. Clinical and Experimental Immunology 158: 287\u2013293.","journal-title":"Clinical and Experimental Immunology"},{"key":"476_CR9","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1136\/postgradmedj-2013-132309","volume":"90","author":"A Shahrakyvahed","year":"2014","unstructured":"Shahrakyvahed, A., J. Sanchooli, N. Sanadgol, M.K. Arababadi, and D. Kennedy. 2014. TLR9: an important molecule in the fight against hepatitis B virus. Postgraduate Medical Journal 90: 396\u2013401.","journal-title":"Postgraduate Medical Journal"},{"key":"476_CR10","doi-asserted-by":"crossref","first-page":"264","DOI":"10.4168\/aair.2016.8.3.264","volume":"8","author":"D-H Kim","year":"2016","unstructured":"Kim, D.-H., J.-H. Sohn, H.-J. Park, et al. 2016. CpG oligodeoxynucleotide inhibits cockroach-induced asthma via induction of IFN-\u03b3+ Th1 cells or Foxp3+ regulatory T cells in the lung. Allergy, Asthma & Immunology Research 8: 264\u2013275.","journal-title":"Allergy, Asthma & Immunology Research"},{"key":"476_CR11","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1067\/mai.2002.122156","volume":"109","author":"JV Santeliz","year":"2002","unstructured":"Santeliz, J.V., G. Van Nest, P. Traquina, E. Larsen, and M. Wills-Karp. 2002. Amb a 1-linked CpG oligodeoxynucleotides reverse established airway hyperresponsiveness in a murine model of asthma. Journal of Allergy and Clinical Immunology 109: 455\u2013462.","journal-title":"Journal of Allergy and Clinical Immunology"},{"issue":"3","key":"476_CR12","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.smim.2010.04.007","volume":"22","author":"TW Dubensky","year":"2010","unstructured":"Dubensky, T.W., and S.G. Reed. 2010. Adjuvants for cancer vaccines. Seminars in Immunology. 22(3): 155\u2013161.","journal-title":"Seminars in Immunology."},{"key":"476_CR13","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/pim.12071","volume":"36","author":"J Joshi","year":"2014","unstructured":"Joshi, J., and S. Kaur. 2014. To investigate the therapeutic potential of immunochemotherapy with cisplatin\u2009+\u200978 kDa\u2009+\u2009MPL-A against Leishmania donovani in BALB\/c mice. Parasite Immunology 36: 3\u201312.","journal-title":"Parasite Immunology"},{"key":"476_CR14","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.intimp.2015.05.027","volume":"28","author":"M Habibi","year":"2015","unstructured":"Habibi, M., M.R. Asadi Karam, and S. Bouzari. 2015. Evaluation of the effect of MPL and delivery route on immunogenicity and protectivity of different formulations of FimH and MrpH from uropathogenic Escherichia coli and Proteus mirabilis in a UTI mouse model. International Immunopharmacology 28: 70\u201378.","journal-title":"International Immunopharmacology"},{"key":"476_CR15","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1189\/jlb.0103026","volume":"74","author":"KA Heldwein","year":"2003","unstructured":"Heldwein, K.A., M.D. Liang, T.K. Andresen, et al. 2003. TLR2 and TLR4 serve distinct roles in the host immune response against Mycobacterium bovis BCG. Journal of Leukocyte Biology 74: 277\u2013286.","journal-title":"Journal of Leukocyte Biology"},{"key":"476_CR16","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1111\/j.1399-3038.2010.01051.x","volume":"21","author":"T Akkoc","year":"2010","unstructured":"Akkoc, T., M. Aydogan, A. Yildiz, et al. 2010. Neonatal BCG vaccination induces IL-10 production by CD4+ CD25+ T cells. Pediatric Allergy and Immunology 21: 1059\u20131063.","journal-title":"Pediatric Allergy and Immunology"},{"key":"476_CR17","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1128\/CVI.00162-15","volume":"22","author":"MC Boer","year":"2015","unstructured":"Boer, M.C., C. Prins, K.E. van Meijgaarden, et al. 2015. Mycobacterium bovis BCG vaccination induces divergent proinflammatory or regulatory T cell responses in adults. Clinical and Vaccine Immunology: CVI 22: 778\u2013788.","journal-title":"Clinical and Vaccine Immunology: CVI"},{"key":"476_CR18","doi-asserted-by":"crossref","first-page":"6240","DOI":"10.1016\/j.vaccine.2014.09.024","volume":"32","author":"C Verwaerde","year":"2014","unstructured":"Verwaerde, C., A.S. Debrie, C. Dombu, et al. 2014. HBHA vaccination may require both Th1 and Th17 immune responses to protect mice against tuberculosis. Vaccine 32: 6240\u20136250.","journal-title":"Vaccine"},{"key":"476_CR19","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/abbs\/gmw010","volume":"48","author":"D Gu","year":"2016","unstructured":"Gu, D., W. Chen, Y. Mi, et al. 2016. The Mycobacterium bovis BCG prime-Rv0577 DNA boost vaccination induces a durable Th1 immune response in mice. Acta Biochimica et Biophysica Sinica 48: 385\u2013390.","journal-title":"Acta Biochimica et Biophysica Sinica"},{"key":"476_CR20","doi-asserted-by":"crossref","first-page":"14274","DOI":"10.1038\/srep14274","volume":"5","author":"M Ballester","year":"2015","unstructured":"Ballester, M., L. Jeanbart, A. de Titta, et al. 2015. Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Scientific Reports 5: 14274.","journal-title":"Scientific Reports"},{"key":"476_CR21","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.anai.2014.08.015","volume":"113","author":"J Ou","year":"2014","unstructured":"Ou, J., W. Shi, Y. Xu, and Z. Tao. 2014. Intranasal immunization with DNA vaccine coexpressing Der p 1 and ubiquitin in an allergic rhinitis mouse model. Annals of Allergy, Asthma & Immunology: Official Publication of the American College of Allergy, Asthma, & Immunology 113: 658\u2013665. e651.","journal-title":"Annals of Allergy, Asthma & Immunology: Official Publication of the American College of Allergy, Asthma, & Immunology"},{"key":"476_CR22","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1046\/j.1365-2567.2003.01609.x","volume":"108","author":"M Lagranderie","year":"2003","unstructured":"Lagranderie, M., M.A. Nahori, A.M. Balazuc, et al. 2003. Dendritic cells recruited to the lung shortly after intranasal delivery of Mycobacterium bovis BCG drive the primary immune response towards a type 1 cytokine production. Immunology 108: 352\u2013364.","journal-title":"Immunology"},{"key":"476_CR23","unstructured":"Patent US3598122. 1982. Google Patents."},{"key":"476_CR24","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.vaccine.2012.10.091","volume":"31","author":"H-B Li","year":"2012","unstructured":"Li, H.-B., J.-Y. Zhang, Y.-F. He, et al. 2012. Systemic immunization with an epitope-based vaccine elicits a Th1-biased response and provides protection against Helicobacter pylori in mice. Vaccine 31: 120\u2013126.","journal-title":"Vaccine"},{"key":"476_CR25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1742-4933-7-1","volume":"7","author":"T Ito","year":"2010","unstructured":"Ito, T., T. Takii, M. Maruyama, et al. 2010. Effectiveness of BCG vaccination to aged mice. Immunity & Ageing 7: 1.","journal-title":"Immunity & Ageing"},{"key":"476_CR26","first-page":"202","volume":"49","author":"I Fern\u00e1ndez","year":"2010","unstructured":"Fern\u00e1ndez, I., A. Pe\u00f1a, N. Del Teso, V. P\u00e9rez, and J. Rodr\u00edguez-Cuesta. 2010. Clinical biochemistry parameters in C57BL\/6J mice after blood collection from the submandibular vein and retroorbital plexus. Journal of the American Association for Laboratory Animal Science 49: 202\u2013206.","journal-title":"Journal of the American Association for Laboratory Animal Science"},{"key":"476_CR27","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4236\/oji.2012.21003","volume":"2","author":"MJ Duechs","year":"2012","unstructured":"Duechs, M.J., J.E. Brunt, F. Gantner, and K.J. Erb. 2012. Adjuvant effects of different TLR agonists on the induction of allergen-specific Th2 responses. Open Journal of Immunology 2: 17.","journal-title":"Open Journal of Immunology"},{"key":"476_CR28","doi-asserted-by":"crossref","first-page":"E784","DOI":"10.1073\/pnas.1316178111","volume":"111","author":"KJ Mackenzie","year":"2014","unstructured":"Mackenzie, K.J., D.J. Nowakowska, M.D. Leech, et al. 2014. Effector and central memory T helper 2 cells respond differently to peptide immunotherapy. Proceedings of the National Academy of Sciences 111: E784\u2013E793.","journal-title":"Proceedings of the National Academy of Sciences"},{"key":"476_CR29","unstructured":"D\u00fcchs M, der Promotionskommission M. 2011. Effects of Toll-like receptor agonists on the pathogenesis of atopic asthma in mice. Universit\u00e4tsbibliothek der Universit\u00e4t W\u00fcrzburg."},{"key":"476_CR30","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1189\/jlb.0710419","volume":"88","author":"MM Coleman","year":"2010","unstructured":"Coleman, M.M., J. Keane, and K.H. Mills. 2010. Editorial: Tregs and BCG\u2014dangerous liaisons in TB. Journal of Leukocyte Biology 88: 1067\u20131069.","journal-title":"Journal of Leukocyte Biology"},{"key":"476_CR31","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/j.it.2011.06.006","volume":"32","author":"LG Gregory","year":"2011","unstructured":"Gregory, L.G., and C.M. Lloyd. 2011. Orchestrating house dust mite-associated allergy in the lung. Trends in Immunology 32: 402\u2013411.","journal-title":"Trends in Immunology"},{"key":"476_CR32","first-page":"207","volume":"5","author":"M Soleimani","year":"2008","unstructured":"Soleimani, M., and J. Rafinejad. 2008. House dust mite contamination in hotels and inns in Bandar Abbas, south of Iran. Journal of Environmental Health Science & Engineering 5: 207\u2013210.","journal-title":"Journal of Environmental Health Science & Engineering"},{"key":"476_CR33","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1159\/000355628","volume":"6","author":"J Kleinnijenhuis","year":"2013","unstructured":"Kleinnijenhuis, J., J. Quintin, F. Preijers, et al. 2013. Long-lasting effects of BCG vaccination on both heterologous Th1\/Th17 responses and innate trained immunity. Journal of Innate Immunity 6: 152\u2013158.","journal-title":"Journal of Innate Immunity"},{"key":"476_CR34","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.molmed.2010.04.008","volume":"16","author":"WR Thomas","year":"2010","unstructured":"Thomas, W.R., B.J. Hales, and W.-A. Smith. 2010. House dust mite allergens in asthma and allergy. Trends in Molecular Medicine 16: 321\u2013328.","journal-title":"Trends in Molecular Medicine"},{"key":"476_CR35","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1398-9995.2006.01002.x","volume":"61","author":"P Moingeon","year":"2006","unstructured":"Moingeon, P., T. Batard, R. Fadel, et al. 2006. Immune mechanisms of allergen-specific sublingual immunotherapy. Allergy 61: 151\u2013165.","journal-title":"Allergy"},{"key":"476_CR36","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1365-2222.2009.03388.x","volume":"40","author":"JR Tversky","year":"2010","unstructured":"Tversky, J.R., A.P. Bieneman, K.L. Chichester, R.G. Hamilton, and J.T. Schroeder. 2010. Subcutaneous allergen immunotherapy restores human dendritic cell innate immune function. Clinical & Experimental Allergy 40: 94\u2013102.","journal-title":"Clinical & Experimental Allergy"},{"key":"476_CR37","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1164\/ajrccm.153.1.8542107","volume":"153","author":"JK Peat","year":"1996","unstructured":"Peat, J.K., E. Tovey, B.G. Toelle, et al. 1996. House dust mite allergens. A major risk factor for childhood asthma in Australia. American Journal of Respiratory and Critical Care Medicine 153: 141\u2013146.","journal-title":"American Journal of Respiratory and Critical Care Medicine"},{"key":"476_CR38","doi-asserted-by":"crossref","unstructured":"Ballester M, Jeanbart L, De Titta A et al. 2015. Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice. Scientific Reports 5.","DOI":"10.1038\/srep14274"},{"key":"476_CR39","doi-asserted-by":"crossref","first-page":"4949","DOI":"10.1128\/JVI.80.10.4949-4961.2006","volume":"80","author":"JL VanCott","year":"2006","unstructured":"VanCott, J.L., A.E. Prada, M.M. McNeal, et al. 2006. Mice develop effective but delayed protective immune responses when immunized as neonates either intranasally with nonliving VP6\/LT (R192G) or orally with live rhesus rotavirus vaccine candidates. Journal of Virology 80: 4949\u20134961.","journal-title":"Journal of Virology"},{"key":"476_CR40","unstructured":"Abbas AK, Lichtman AH, Pillai S. 2011. Cellular and molecular immunology. Elsevier Health Sciences."},{"key":"476_CR41","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/aor.12566","volume":"40","author":"P Gong","year":"2016","unstructured":"Gong, P., Y. Li, Y.P. Tan, and H. Li. 2016. Pretreatment with inactivated Bacillus Calmette-Guerin increases CD4+CD25+ regulatory T cell function and decreases functional and structural effects of asthma induction in a rat asthma model. Artificial Organs 40: 360\u2013367.","journal-title":"Artificial Organs"},{"key":"476_CR42","doi-asserted-by":"crossref","first-page":"6911","DOI":"10.1016\/j.vaccine.2014.10.041","volume":"32","author":"DA Kaveh","year":"2014","unstructured":"Kaveh, D.A., M. Carmen Garcia-Pelayo, and P.J. Hogarth. 2014. Persistent BCG bacilli perpetuate CD4 T effector memory and optimal protection against tuberculosis. Vaccine 32: 6911\u20136918.","journal-title":"Vaccine"},{"key":"476_CR43","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.molimm.2015.03.008","volume":"66","author":"Y Shi","year":"2015","unstructured":"Shi, Y., M.A. Felder, P.M. Sondel, and A.L. Rakhmilevich. 2015. Synergy of anti-CD40, CpG and MPL in activation of mouse macrophages. Molecular Immunology 66: 208\u2013215.","journal-title":"Molecular Immunology"},{"key":"476_CR44","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1007\/s10875-012-9746-4","volume":"33","author":"AC Gouveia","year":"2013","unstructured":"Gouveia, A.C., A.S. Brugiolo, C.C. Alves, et al. 2013. Th2 responses in OVA-sensitized BALB\/c mice are down-modulated by Mycobacterium bovis BCG treatment. Journal of Clinical Immunology 33: 235\u2013245.","journal-title":"Journal of Clinical Immunology"},{"key":"476_CR45","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.autrev.2013.12.004","volume":"13","author":"M Noack","year":"2014","unstructured":"Noack, M., and P. Miossec. 2014. Th17 and regulatory T cell balance in autoimmune and inflammatory diseases. Autoimmunity Reviews 13: 668\u2013677.","journal-title":"Autoimmunity Reviews"},{"key":"476_CR46","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.immuni.2009.08.007","volume":"31","author":"CM Lloyd","year":"2009","unstructured":"Lloyd, C.M., and C.M. Hawrylowicz. 2009. Regulatory T cells in asthma. Immunity 31: 438\u2013449.","journal-title":"Immunity"},{"key":"476_CR47","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1038\/ng.3098","volume":"46","author":"P Xu","year":"2014","unstructured":"Xu, P., X. Zhang, X. Wang, et al. 2014. Genome sequence and genetic diversity of the common carp, Cyprinus carpio. Nature Genetics 46: 1212\u20131219.","journal-title":"Nature Genetics"},{"key":"476_CR48","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1034\/j.1600-065X.2000.17717.x","volume":"177","author":"F Sallusto","year":"2000","unstructured":"Sallusto, F., and A. Lanzavecchia. 2000. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunological Reviews 177: 134\u2013140.","journal-title":"Immunological Reviews"},{"key":"476_CR49","unstructured":"Salehi S. 2013. The role of Syk in airway hyperresponsiveness and remodeling in house dust mite induced murine models of allergic airways inflammation. Toronto University."},{"key":"476_CR50","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1136\/ard.2006.065961","volume":"66","author":"K Tao","year":"2007","unstructured":"Tao, K., M. Fujii, Tsukumo S-i, et al. 2007. Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population. Annals of the Rheumatic Diseases 66: 905\u2013909.","journal-title":"Annals of the Rheumatic Diseases"},{"key":"476_CR51","doi-asserted-by":"crossref","unstructured":"Boer MC, Joosten SA, Ottenhoff TH. 2015. Regulatory T-cells at the interface between human host and pathogens in infectious diseases and vaccination. Frontiers in Immunology 6.","DOI":"10.3389\/fimmu.2015.00217"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-016-0476-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-016-0476-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-016-0476-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T20:52:08Z","timestamp":1718916728000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-016-0476-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11,28]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["476"],"URL":"https:\/\/doi.org\/10.1007\/s10753-016-0476-2","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"type":"print","value":"0360-3997"},{"type":"electronic","value":"1573-2576"}],"subject":[],"published":{"date-parts":[[2016,11,28]]}}}