{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:36:31Z","timestamp":1793655391591,"version":"4.5.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T00:00:00Z","timestamp":1494374400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Specialized Fund of Hubei Provincial Department of Education in Hubei Provincial Collaborative Innovation Center of Preventive Treatment by Acupuncture and Moxibustion","award":["No. HBPCIC-2016-004"],"award-info":[{"award-number":["No. HBPCIC-2016-004"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s10753-017-0578-5","type":"journal-article","created":{"date-parts":[[2017,5,10]],"date-time":"2017-05-10T04:30:52Z","timestamp":1494390652000},"page":"1351-1364","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Electro-Acupuncture at Zusanli Acupoint (ST36) Suppresses Inflammation in Allergic Contact Dermatitis Via Triggering Local IL-10 Production and Inhibiting p38 MAPK Activation"],"prefix":"10.1007","volume":"40","author":[{"given":"Zhigang","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Long","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yisen","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhao","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenwei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zebin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,5,10]]},"reference":[{"key":"578_CR1","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/cea.12495","volume":"45","author":"W Peng","year":"2015","unstructured":"Peng, W., and N. Novak. 2015. Pathogenesis of atopic dermatitis. Clinical and Experimental Allergy 45: 566\u2013574.","journal-title":"Clinical and Experimental Allergy"},{"key":"578_CR2","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/nri3150","volume":"12","author":"DH Kaplan","year":"2012","unstructured":"Kaplan, D.H., B.Z. Igy\u00e1rt\u00f3, and A.A. Gaspari. 2012. Early immune events in the induction of allergic contact dermatitis. Nature Reviews. Immunology 12: 114\u2013124.","journal-title":"Nature Reviews. Immunology"},{"key":"578_CR3","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1111\/all.12529","volume":"69","author":"C Schlapbach","year":"2014","unstructured":"Schlapbach, C., and D. Simon. 2014. Update on skin allergy. Allergy 69: 1571\u20131581.","journal-title":"Allergy"},{"key":"578_CR4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.3727\/036012908803861168","volume":"33","author":"JB Han","year":"2008","unstructured":"Han, J.B., C.W. Kim, B. Sun, S.K. Kim, M.G. Lee, D.S. Park, et al. 2008. The antipruritic effect of acupuncture on serotonin-evoked itch in rats. Acupunct Electrother Res 33: 145\u2013156.","journal-title":"Acupunct Electrother Res"},{"key":"578_CR5","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1186\/s12906-016-1019-y","volume":"16","author":"B Sur","year":"2016","unstructured":"Sur, B., B. Lee, M. Yeom, J.H. Hong, S. Kwon, S.T. Kim, et al. 2016. Bee venom acupuncture alleviates trimellitic anhydride-induced atopic dermatitis-like skin lesions in mice. BMC Complementary and Alternative Medicine 16: 38.","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"578_CR6","doi-asserted-by":"crossref","first-page":"e007704","DOI":"10.1136\/bmjopen-2015-007704","volume":"5","author":"Q Yao","year":"2015","unstructured":"Yao, Q., Y. Ye, X. Liu, Z. Qin, and Z. Liu. 2015. Acupuncture for patients with chronic urticaria: A systematic review protocol. BMJ Open 5: e007704.","journal-title":"BMJ Open"},{"key":"578_CR7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1472-6882-11-46","volume":"11","author":"T Ursini","year":"2011","unstructured":"Ursini, T., M. Tontodonati, L. Manzoli, E. Polilli, C. Rebuzzi, G. Congedo, et al. 2011. Acupuncture for the treatment of severe acute pain in herpes zoster: Results of a nested, open-label, randomized trial in the VZV pain study. BMC Complementary and Alternative Medicine 11: 46.","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"578_CR8","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1111\/ced.12732","volume":"40","author":"HY Tan","year":"2015","unstructured":"Tan, H.Y., G.B. Lenon, A.L. Zhang, and C.C. Xue. 2015. Efficacy of acupuncture in the management of atopic dermatitis: A systematic review. Clinical and Experimental Dermatology 40: 711\u2013715.","journal-title":"Clinical and Experimental Dermatology"},{"key":"578_CR9","doi-asserted-by":"crossref","first-page":"37846","DOI":"10.1038\/srep37846","volume":"6","author":"Q Shu","year":"2016","unstructured":"Shu, Q., H. Wang, D. Litscher, S. Wu, L. Chen, I. Gaischek, et al. 2016. Acupuncture and Moxibustion have different effects on fatigue by regulating the autonomic nervous system: A pilot controlled clinical trial. Scientific Reports 6: 37846.","journal-title":"Scientific Reports"},{"key":"578_CR10","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1398-9995.2012.02789.x","volume":"67","author":"F Pfab","year":"2012","unstructured":"Pfab, F., M.T. Kirchner, J. Huss-Marp, T. Schuster, P.C. Schalock, J. Fuqin, et al. 2012. Acupuncture compared with oral antihistamine for type I hypersensitivity itch and skin response in adults with atopic dermatitis: A patient- and examiner-blinded, randomized, placebo-controlled, crossover trial. Allergy 67: 566\u2013573.","journal-title":"Allergy"},{"key":"578_CR11","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1111\/j.1398-9995.2009.02284.x","volume":"65","author":"F Pfab","year":"2010","unstructured":"Pfab, F., J. Huss-Marp, A. Gatti, J. Fuqin, G.I. Athanasiadis, D. Irnich, et al. 2010. Influence of acupuncture on type I hypersensitivity itch and the wheal and flare response in adults with atopic eczema - a blinded, randomized, placebo-controlled, crossover trial. Allergy 65: 903\u2013910.","journal-title":"Allergy"},{"key":"578_CR12","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1089\/acm.2009.0684","volume":"17","author":"F Pfab","year":"2011","unstructured":"Pfab, F., G.I. Athanasiadis, J. Huss-Marp, J. Fuqin, B. Heuser, L. Cifuentes, et al. 2011. Effect of acupuncture on allergen-induced basophil activation in patients with atopic eczema: A pilot trial. Journal of Alternative and Complementary Medicine 17: 309\u2013314.","journal-title":"Journal of Alternative and Complementary Medicine"},{"key":"578_CR13","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1136\/acupmed-2011-010088","volume":"30","author":"KC Lee","year":"2012","unstructured":"Lee, K.C., A. Keyes, J.R. Hensley, J.R. Gordon, M.J. Kwasny, D.P. West, et al. 2012. Effectiveness of acupressure on pruritus and lichenification associated with atopic dermatitis: A pilot trial. Acupuncture in Medicine 30: 8\u201311.","journal-title":"Acupuncture in Medicine"},{"key":"578_CR14","doi-asserted-by":"crossref","first-page":"647308","DOI":"10.1155\/2012\/647308","volume":"2012","author":"Y Kwon","year":"2012","unstructured":"Kwon, Y., S.H. Sohn, G. Lee, Y. Kim, H. Lee, M. Shin, et al. 2012. Electroacupuncture attenuates ovalbumin-induced allergic asthma via modulating CD4(+)CD25(+) regulatory T cells. Evidence-based Complementary and Alternative Medicine 2012: 647308.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"578_CR15","doi-asserted-by":"crossref","first-page":"798081","DOI":"10.1093\/ecam\/nep240","volume":"2011","author":"AR Kim","year":"2011","unstructured":"Kim, A.R., J.Y. Choi, J.I. Kim, S.Y. Jung, and S.M. Choi. 2011. Acupuncture treatment of a patient with persistent allergic rhinitis complicated by rhinosinusitis and asthma. Evidence-based Complementary and Alternative Medicine 2011: 798081.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"578_CR16","doi-asserted-by":"crossref","first-page":"e51573","DOI":"10.1371\/journal.pone.0051573","volume":"8","author":"Y Liu","year":"2013","unstructured":"Liu, Y., H. Wang, X. Wang, L. Mu, Q. Kong, D. Wang, et al. 2013. The mechanism of effective electroacupuncture on T cell response in rats with experimental autoimmune encephalomyelitis. PloS One 8: e51573.","journal-title":"PloS One"},{"key":"578_CR17","doi-asserted-by":"crossref","first-page":"942196","DOI":"10.1155\/2014\/942196","volume":"2014","author":"TY Ho","year":"2014","unstructured":"Ho, T.Y., H.Y. Lo, D.C. Chao, C.C. Li, J.J. Liu, C. Lin, et al. 2014. Electroacupuncture improves trinitrobenzene sulfonic acid-induced colitis, evaluated by transcriptomic study. Evidence-based Complementary and Alternative Medicine 2014: 942196.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"578_CR18","unstructured":"Dong ZQ, Zhu J, Lu DZ, Chen Q and Xu YL. 2016. Effect of Electroacupuncture in \u201cZusanli\u201d and \u201cKunlun\u201d Acupoints on TLR4 Signaling Pathway of Adjuvant Arthritis Rats. American Journal Therapeutics."},{"key":"578_CR19","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.jdermsci.2013.11.015","volume":"74","author":"DL Jung","year":"2014","unstructured":"Jung, D.L., S.D. Lee, I.H. Choi, H.S. Na, and S.U. Hong. 2014. Effects of electroacupuncture on capsaicin-induced model of atopic dermatitis in rats. Journal of Dermatological Science 74: 23\u201330.","journal-title":"Journal of Dermatological Science"},{"key":"578_CR20","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/jid.2012.284","volume":"133","author":"T Honda","year":"2013","unstructured":"Honda, T., G. Egawa, S. Grabbe, and K. Kabashima. 2013. Update of immune events in the murine contact hypersensitivity model: Toward the understanding of allergic contact dermatitis. The Journal of Investigative Dermatology 133: 303\u2013315.","journal-title":"The Journal of Investigative Dermatology"},{"key":"578_CR21","doi-asserted-by":"crossref","first-page":"e113143","DOI":"10.1371\/journal.pone.0113143","volume":"9","author":"Z Hussain","year":"2014","unstructured":"Hussain, Z., H. Katas, M.C. Mohd Amin, and E. Kumolosasi. 2014. Efficient immuno-modulation of TH1\/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: Nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs. PloS One 9: e113143.","journal-title":"PloS One"},{"key":"578_CR22","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.anai.2010.10.020","volume":"106","author":"MS Kim","year":"2011","unstructured":"Kim, M.S., Y.G. Hur, W.G. Kim, B.W. Park, K.S. Ahn, J.J. Kim, et al. 2011. Inhibitory effect of Platycodon grandiflorum on T(H)1 and T(H)2 immune responses in a murine model of 2,4-dinitrofluorobenzene-induced atopic dermatitis-like skin lesions. Annals of Allergy, Asthma & Immunology 106: 54\u201361.","journal-title":"Annals of Allergy, Asthma & Immunology"},{"key":"578_CR23","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1745-6215-10-54","volume":"10","author":"JI Kim","year":"2009","unstructured":"Kim, J.I., M.S. Lee, S.Y. Jung, J.Y. Choi, S. Lee, J.M. Ko, et al. 2009. Acupuncture for persistent allergic rhinitis: A multi-centre, randomised, controlled trial protocol. Trials 10: 54.","journal-title":"Trials"},{"key":"578_CR24","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1159\/000446044","volume":"50","author":"IH Chan","year":"2016","unstructured":"Chan, I.H., and D.F. Murrell. 2016. Itch management: Physical approaches (UV phototherapy, acupuncture). Current Problems in Dermatology 50: 54\u201363.","journal-title":"Current Problems in Dermatology"},{"key":"578_CR25","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/j.jams.2016.07.006","volume":"9","author":"YC Jeon","year":"2016","unstructured":"Jeon, Y.C., and H.B. Lee. 2016. Treatment of an adult patient with atopic dermatitis using Traditional Korean medicine, especially Sa-am acupuncture. Journal of Acupuncture and Meridian Studies 9: 322\u2013324.","journal-title":"Journal of Acupuncture and Meridian Studies"},{"key":"578_CR26","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s10753-016-0487-z","volume":"40","author":"Z Wang","year":"2017","unstructured":"Wang, Z., T. Chen, M. Long, L. Chen, L. Wang, N. Yin, et al. 2017. Electro-acupuncture at Acupoint ST36 ameliorates inflammation and regulates Th1\/Th2 balance in delayed-type hypersensitivity. Inflammation 40: 422\u2013434.","journal-title":"Inflammation"},{"key":"578_CR27","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1590\/S0102-86502014001900004","volume":"29","author":"AC Goes","year":"2014","unstructured":"Goes, A.C., F.M. Pinto, G.C. Fernandes, J.S. Barbosa, E.S. Correia, R.A. Ribeiro, et al. 2014. Electroacupuncture ameliorates experimental colitis induced by TNBS through activation of interleukin-10 and inhibition of iNOS in mice. Acta Cir\u00fargica Brasileira 29: 787\u2013793.","journal-title":"Acta Cir\u00fargica Brasileira"},{"key":"578_CR28","doi-asserted-by":"crossref","first-page":"217946","DOI":"10.1093\/ecam\/neq036","volume":"2011","author":"MD Silva da","year":"2011","unstructured":"da Silva, M.D., G. Guginski, M.F. Werner, C.H. Baggio, R. Marcon, and A.R. Santos. 2011. Involvement of interleukin-10 in the anti-inflammatory effect of Sanyinjiao (SP6) acupuncture in a mouse model of peritonitis. Evidence-based Complementary and Alternative Medicine 2011: 217946.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"578_CR29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s12035-014-8790-x","volume":"51","author":"MD Silva da","year":"2015","unstructured":"da Silva, M.D., F. Bobinski, K.L. Sato, S.J. Kolker, K.A. Sluka, and A.R. Santos. 2015. IL-10 cytokine released from M2 macrophages is crucial for analgesic and anti-inflammatory effects of acupuncture in a model of inflammatory muscle pain. Molecular Neurobiology 51: 19\u201331.","journal-title":"Molecular Neurobiology"},{"key":"578_CR30","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/nri2448","volume":"8","author":"DM Mosser","year":"2008","unstructured":"Mosser, D.M., and J.P. Edwards. 2008. Exploring the full spectrum of macrophage activation. Nature Reviews. Immunology 8: 958\u2013969.","journal-title":"Nature Reviews. Immunology"},{"key":"578_CR31","doi-asserted-by":"crossref","first-page":"2838","DOI":"10.4049\/jimmunol.1501923","volume":"197","author":"A Howes","year":"2016","unstructured":"Howes, A., C. Taubert, S. Blankley, N. Spink, X. Wu, C.M. Graham, et al. 2016. Differential production of type I IFN determines the reciprocal levels of IL-10 and Proinflammatory cytokines produced by C57BL\/6 and BALB\/c macrophages. Journal of Immunology 197: 2838\u20132853.","journal-title":"Journal of Immunology"},{"key":"578_CR32","doi-asserted-by":"crossref","first-page":"26489","DOI":"10.1038\/srep26489","volume":"6","author":"M Kobayashi","year":"2016","unstructured":"Kobayashi, M., F. Usui, T. Karasawa, A. Kawashima, H. Kimura, Y. Mizushina, et al. 2016. NLRP3 deficiency reduces macrophage interleukin-10 production and enhances the susceptibility to doxorubicin-induced cardiotoxicity. Scientific Reports 6: 26489.","journal-title":"Scientific Reports"},{"key":"578_CR33","doi-asserted-by":"crossref","first-page":"ra121","DOI":"10.1126\/scisignal.aab3156","volume":"8","author":"YR Na","year":"2015","unstructured":"Na, Y.R., D. Jung, G.J. Gu, A.R. Jang, Y.H. Suh, and S.H. Seok. 2015. The early synthesis of p35 and activation of CDK5 in LPS-stimulated macrophages suppresses interleukin-10 production. Science Signaling 8: ra121.","journal-title":"Science Signaling"},{"key":"578_CR34","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/1478-811X-11-95","volume":"11","author":"D Dibra","year":"2013","unstructured":"Dibra, D., and S. Li. 2013. The cell-to-cell coordination between activated T cells and CpG-stimulated macrophages synergistically induce elevated levels of IL-10 via NF-\u03baB1, STAT3, and CD40\/CD154. Cell Communication and Signaling: CCS 11: 95.","journal-title":"Cell Communication and Signaling: CCS"},{"key":"578_CR35","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.cyto.2016.06.018","volume":"85","author":"RL Lopes","year":"2016","unstructured":"Lopes, R.L., T.J. Borges, R.F. Zanin, and C. Bonorino. 2016. IL-10 is required for polarization of macrophages to M2-like phenotype by mycobacterial DnaK (heat shock protein 70). Cytokine 85: 123\u2013129.","journal-title":"Cytokine"},{"key":"578_CR36","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.1002\/bit.25175","volume":"111","author":"RM Boehler","year":"2014","unstructured":"Boehler, R.M., R. Kuo, S. Shin, A.G. Goodman, M.A. Pilecki, R.M. Gower, et al. 2014. Lentivirus delivery of IL-10 to promote and sustain macrophage polarization towards an anti-inflammatory phenotype. Biotechnology and Bioengineering 111: 1210\u20131221.","journal-title":"Biotechnology and Bioengineering"},{"key":"578_CR37","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/j.jaci.2011.05.043","volume":"128","author":"E Gros","year":"2011","unstructured":"Gros, E., S. Petzold, L. Maintz, T. Bieber, and N. Novak. 2011. Reduced IFN-\u03b3 receptor expression and attenuated IFN-\u03b3 response by dendritic cells in patients with atopic dermatitis. The Journal of Allergy and Clinical Immunology 128: 1015\u20131021.","journal-title":"The Journal of Allergy and Clinical Immunology"},{"key":"578_CR38","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/j.1348-0421.2012.12006.x","volume":"57","author":"K Matsui","year":"2013","unstructured":"Matsui, K., and A. Nishikawa. 2013. Peptidoglycan-induced T helper 2 immune response in mice involves interleukin-10 secretion from Langerhans cells. Microbiology and Immunology 57: 130\u2013138.","journal-title":"Microbiology and Immunology"},{"key":"578_CR39","doi-asserted-by":"crossref","unstructured":"Meephansan, J., H. Tsuda, M. Komine, S. Tominaga, and M. Ohtsuki. Regulation of IL-33 expression by IFN-\u03b3 and tumor necrosis factor-\u03b1 in normal human epidermal keratinocytes. The Journal of Investigative Dermatology 132: 2593\u20132600.","DOI":"10.1038\/jid.2012.185"},{"key":"578_CR40","first-page":"592127","volume":"2013","author":"S Hu","year":"2013","unstructured":"Hu, S., M.H. Du, H.M. Luo, H. Wang, Y. Lv, L. Ma, et al. 2013. Electroacupuncture at Zusanli (ST36) prevents intestinal barrier and remote organ dysfunction following gut ischemia through activating the cholinergic anti-inflammatory-dependent mechanism. Evidence-based Complementary and Alternative Medicine 2013: 592127.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"578_CR41","doi-asserted-by":"crossref","first-page":"469","DOI":"10.4314\/ajtcam.v11i2.35","volume":"11","author":"Q Song","year":"2014","unstructured":"Song, Q., S. Hu, H. Wang, Y. Lv, X. Shi, Z. Sheng, et al. 2014. Electroacupuncturing at Zusanli point (ST36) attenuates pro-inflammatory cytokine release and organ dysfunction by activating cholinergic anti-inflammatory pathway in rat with endotoxin challenge. African Journal of Traditional, Complementary, and Alternative Medicines 11: 469\u2013474.","journal-title":"African Journal of Traditional, Complementary, and Alternative Medicines"},{"key":"578_CR42","doi-asserted-by":"crossref","first-page":"e6638","DOI":"10.1371\/journal.pone.0006638","volume":"4","author":"Y Feng","year":"2009","unstructured":"Feng, Y., J. Johansson, R. Shao, L. Manner\u00e5s, J. Fernandez-Rodriguez, H. Billig, et al. 2009. Hypothalamic neuroendocrine functions in rats with dihydrotestosterone-induced polycystic ovary syndrome: Effects of low-frequency electro-acupuncture. PloS One 4: e6638.","journal-title":"PloS One"},{"key":"578_CR43","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.neulet.2016.01.004","volume":"615","author":"JJ Le","year":"2016","unstructured":"Le, J.J., T. Yi, L. Qi, J. Li, L. Shao, and J.C. Dong. 2016. Electroacupuncture regulate hypothalamic-pituitary-adrenal axis and enhance hippocampal serotonin system in a rat model of depression. Neuroscience Letters 615: 66\u201371.","journal-title":"Neuroscience Letters"},{"key":"578_CR44","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/nm.3479","volume":"20","author":"R Torres-Rosas","year":"2014","unstructured":"Torres-Rosas, R., G. Yehia, G. Pe\u00f1a, P. Mishra, M. del Rocio Thompson-Bonilla, M.A. Moreno-Eutimio, et al. 2014. Dopamine mediates vagal modulation of the immune system by electroacupuncture. Nature Medicine 20: 291\u2013295.","journal-title":"Nature Medicine"},{"key":"578_CR45","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1136\/acupmed-2013-010460","volume":"32","author":"F Liu","year":"2014","unstructured":"Liu, F., J. Fang, X. Shao, Y. Liang, Y. Wu, and Y. Jin. 2014. Electroacupuncture exerts an anti-inflammatory effect in a rat tissue chamber model of inflammation via suppression of NF-\u03baB activation. Acupuncture in Medicine 32: 340\u2013345.","journal-title":"Acupuncture in Medicine"},{"key":"578_CR46","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1186\/1472-6882-14-137","volume":"14","author":"Q Yang","year":"2014","unstructured":"Yang, Q., Y.D. Xie, M.X. Zhang, B. Huang, C. Zhang, H.Y. Li, et al. 2014. Effect of electroacupuncture stimulation at Zusanli acupoint (ST36) on gastric motility: Possible through PKC and MAPK signal transduction pathways. BMC Complementary and Alternative Medicine 14: 137.","journal-title":"BMC Complementary and Alternative Medicine"},{"key":"578_CR47","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1007\/s12013-014-0044-z","volume":"70","author":"M Li","year":"2014","unstructured":"Li, M., K. Gu, M. Chi, X. Sun, J. Gu, and G. Wang. 2014. p38 mitogen-activated protein kinase is required for electroacupuncture restoration of CD4+\/CD8+ homeostasis and cytokine expression in a rodent model of surgical trauma. Cell Biochemistry and Biophysics 70: 1213\u20131218.","journal-title":"Cell Biochemistry and Biophysics"},{"key":"578_CR48","first-page":"982095","volume":"2013","author":"JY Park","year":"2013","unstructured":"Park, J.Y., H.J. Park, Y.Y. Choi, M.H. Kim, S.N. Kim, and W.M. Yang. 2013. Effects of acupuncture on 1-chloro-2, 4-dinitrochlorobenzene-induced atopic dermatitis. Evidence-based Complementary and Alternative Medicine 2013: 982095.","journal-title":"Evidence-based Complementary and Alternative Medicine"},{"key":"578_CR49","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.taap.2008.03.012","volume":"230","author":"S Trompezinski","year":"2008","unstructured":"Trompezinski, S., C. Migdal, M. Tailhardat, B. Le Varlet, P. Courtellemont, M. Haftek, et al. 2008. Characterization of early events involved in human dendritic cell maturation induced by sensitizers: Cross talk between MAPK signalling pathways. Toxicology and Applied Pharmacology 230: 397\u2013406.","journal-title":"Toxicology and Applied Pharmacology"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-017-0578-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-017-0578-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-017-0578-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T11:07:02Z","timestamp":1750244822000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-017-0578-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,10]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["578"],"URL":"https:\/\/doi.org\/10.1007\/s10753-017-0578-5","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,10]]}}}