{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T18:23:54Z","timestamp":1772821434226,"version":"3.50.1"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T00:00:00Z","timestamp":1494460800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81500572"],"award-info":[{"award-number":["81500572"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81472401"],"award-info":[{"award-number":["81472401"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science and Technology Key Project on Clinical Medicine of Jiangsu Province","award":["BL2013013"],"award-info":[{"award-number":["BL2013013"]}]},{"name":"Medicine and Hygiene Program of Zhejiang Province","award":["2014KYB231"],"award-info":[{"award-number":["2014KYB231"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s10753-017-0582-9","type":"journal-article","created":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T11:19:23Z","timestamp":1494501563000},"page":"1393-1400","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["IL-35 Pretreatment Alleviates Lipopolysaccharide-Induced Acute Kidney Injury in Mice by Inhibiting NF-\u03baB Activation"],"prefix":"10.1007","volume":"40","author":[{"given":"Linkun","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuefeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haiyan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianquan","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,11]]},"reference":[{"issue":"6","key":"582_CR1","doi-asserted-by":"publisher","first-page":"R700","DOI":"10.1186\/cc3879","volume":"9","author":"SM Bagshaw","year":"2005","unstructured":"Bagshaw, S.M., K.B. Laupland, C.J. Doig, G. Mortis, G.H. Fick, M. Mucenski, T. Godinez-Luna, L.W. Svenson, and T. Rosenal. 2005. Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: A population-based study. Critical Care 9 (6): R700\u2013R709. doi:\n10.1186\/cc3879\n\n.","journal-title":"Critical Care"},{"issue":"10","key":"582_CR2","doi-asserted-by":"crossref","first-page":"6898","DOI":"10.4049\/jimmunol.181.10.6898","volume":"181","author":"E Bardel","year":"2008","unstructured":"Bardel, E., F. Larousserie, P. Charlot-Rabiega, A. Coulomb-L'Hermine, and O. Devergne. 2008. Human CD4+ CD25+ Foxp3+ regulatory T cells do not constitutively express IL-35. Journal of Immunology 181 (10): 6898\u20136905.","journal-title":"Journal of Immunology"},{"issue":"2","key":"582_CR3","first-page":"131","volume":"24","author":"ML Castellani","year":"2010","unstructured":"Castellani, M.L., A. Anogeianaki, P. Felaco, E. Toniato, M.A. De Lutiis, B. Shaik, M. Fulcheri, et al. 2010. IL-35, an anti-inflammatory cytokine which expands CD4+CD25+ Treg cells. Journal of Biological Regulators and Homeostatic Agents 24 (2): 131\u2013135.","journal-title":"Journal of Biological Regulators and Homeostatic Agents"},{"issue":"12","key":"582_CR4","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1038\/ki.2011.42","volume":"79","author":"LS Chawla","year":"2011","unstructured":"Chawla, L.S., R.L. Amdur, S. Amodeo, P.L. Kimmel, and C.E. Palant. 2011. The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney International 79 (12): 1361\u20131369. doi:\n10.1038\/ki.2011.42\n\n.","journal-title":"Kidney International"},{"issue":"1","key":"582_CR5","doi-asserted-by":"publisher","first-page":"22","DOI":"10.2215\/CJN.02510706","volume":"2","author":"LS Chawla","year":"2007","unstructured":"Chawla, L.S., M.G. Seneff, D.R. Nelson, M. Williams, H. Levy, P.L. Kimmel, and W.L. Macias. 2007. Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis. Clinical Journal of the American Society of Nephrology 2 (1): 22\u201330. doi:\n10.2215\/CJN.02510706\n\n.","journal-title":"Clinical Journal of the American Society of Nephrology"},{"issue":"7169","key":"582_CR6","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1038\/nature06306","volume":"450","author":"LW Collison","year":"2007","unstructured":"Collison, L.W., C.J. Workman, T.T. Kuo, K. Boyd, Y. Wang, K.M. Vignali, R. Cross, D. Sehy, R.S. Blumberg, and D.A. Vignali. 2007. The inhibitory cytokine IL-35 contributes to regulatory T-cell function. Nature 450 (7169): 566\u2013569. doi:\n10.1038\/nature06306\n\n.","journal-title":"Nature"},{"issue":"10","key":"582_CR7","doi-asserted-by":"publisher","first-page":"2868","DOI":"10.1172\/JCI39421","volume":"119","author":"K Doi","year":"2009","unstructured":"Doi, K., A. Leelahavanichkul, P.S. Yuen, and R.A. Star. 2009. Animal models of sepsis and sepsis-induced kidney injury. The Journal of Clinical Investigation 119 (10): 2868\u20132878. doi:\n10.1172\/JCI39421\n\n.","journal-title":"The Journal of Clinical Investigation"},{"key":"582_CR8","doi-asserted-by":"publisher","unstructured":"Duann, P., E.A. Lianos, J. Ma, and P. H. Lin. 2016. Autophagy, Innate Immunity and Tissue Repair in Acute Kidney Injury. Int J Mol Sci 17 (5). doi:\n10.3390\/ijms17050662\n\n.","DOI":"10.3390\/ijms17050662"},{"issue":"26","key":"582_CR9","doi-asserted-by":"publisher","first-page":"39497","DOI":"10.18632\/oncotarget.8347","volume":"7","author":"HY Fan","year":"2016","unstructured":"Fan, H.Y., D. Qi, C. Yu, F. Zhao, T. Liu, Z.K. Zhang, M.Y. Yang, L.M. Zhang, D.Q. Chen, and Y. Du. 2016. Paeonol protects endotoxin-induced acute kidney injury: Potential mechanism of inhibiting TLR4-NF-kappaB signal pathway. Oncotarget 7 (26): 39497\u201339510. doi:\n10.18632\/oncotarget.8347\n\n.","journal-title":"Oncotarget"},{"issue":"6","key":"582_CR10","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.3934\/mbe.2015.12.1203","volume":"12","author":"A Friedman","year":"2015","unstructured":"Friedman, A., and K.L. Liao. 2015. The role of the cytokines IL-27 and IL-35 in cancer. Mathematical Biosciences and Engineering 12 (6): 1203\u20131217. doi:\n10.3934\/mbe.2015.12.1203\n\n.","journal-title":"Mathematical Biosciences and Engineering"},{"issue":"3","key":"582_CR11","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1681\/ASN.2007040469","volume":"19","author":"DN Grigoryev","year":"2008","unstructured":"Grigoryev, D.N., M. Liu, H.T. Hassoun, C. Cheadle, K.C. Barnes, and H. Rabb. 2008. The local and systemic inflammatory transcriptome after acute kidney injury. Journal of the American Society of Nephrology 19 (3): 547\u2013558. doi:\n10.1681\/ASN.2007040469\n\n.","journal-title":"Journal of the American Society of Nephrology"},{"key":"582_CR12","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-016-0453-9","author":"SY Guan","year":"2016","unstructured":"Guan, S.Y., R.X. Leng, M.I. Khan, H. Qureshi, X.P. Li, D.Q. Ye, and H.F. Pan. 2016. Interleukin-35: a potential therapeutic agent for autoimmune diseases. Inflammation. doi:\n10.1007\/s10753-016-0453-9\n\n.","journal-title":"Inflammation"},{"issue":"22","key":"582_CR13","doi-asserted-by":"crossref","first-page":"2347","DOI":"10.1056\/NEJM200411253512224","volume":"351","author":"GA Heresi","year":"2004","unstructured":"Heresi, G.A. 2004. Acute renal failure and sepsis. The New England Journal of Medicine 351 (22): 2347\u20132349 author reply 2347-2349.","journal-title":"The New England Journal of Medicine"},{"issue":"2","key":"582_CR14","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1007\/s10753-015-0281-3","volume":"39","author":"J Hu","year":"2016","unstructured":"Hu, J., and J. Liu. 2016. Licochalcone A attenuates lipopolysaccharide-induced acute kidney injury by inhibiting NF-kappaB activation. Inflammation 39 (2): 569\u2013574. doi:\n10.1007\/s10753-015-0281-3\n\n.","journal-title":"Inflammation"},{"issue":"5","key":"582_CR15","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1159\/000453165","volume":"40","author":"S Jiang","year":"2016","unstructured":"Jiang, S., Y. Li, T. Lin, L. Yuan, Y. Li, S. Wu, L. Xia, H. Shen, and J. Lu. 2016. IL-35 inhibits angiogenesis through VEGF\/Ang2\/Tie2 pathway in rheumatoid arthritis. Cellular Physiology and Biochemistry 40 (5): 1105\u20131116. doi:\n10.1159\/000453165\n\n.","journal-title":"Cellular Physiology and Biochemistry"},{"issue":"10","key":"582_CR16","first-page":"18861","volume":"8","author":"L Jin","year":"2015","unstructured":"Jin, L., X. Xu, B. Ye, M. Pan, Z. Shi, and Y. Hu. 2015. Elevated serum interleukin-35 levels correlate with poor prognosis in patients with clear cell renal cell carcinoma. International Journal of Clinical and Experimental Medicine 8 (10): 18861\u201318866.","journal-title":"International Journal of Clinical and Experimental Medicine"},{"issue":"5","key":"582_CR17","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1007\/s00063-013-0337-9","volume":"109","author":"M Joannidis","year":"2014","unstructured":"Joannidis, M., and H.P. Kierdorf. 2014. Acute kidney injury and its treatment. Med Klin Intensivmed Notfmed 109 (5): 322\u2013323. doi:\n10.1007\/s00063-013-0337-9\n\n.","journal-title":"Med Klin Intensivmed Notfmed"},{"issue":"1","key":"582_CR18","doi-asserted-by":"publisher","first-page":"119","DOI":"10.4049\/jimmunol.1600506","volume":"198","author":"K Kanai","year":"2017","unstructured":"Kanai, K., A.M. Park, H. Yoshida, I. Tsunoda, and O. Yoshie. 2017. IL-35 suppresses lipopolysaccharide-induced airway eosinophilia in EBI3-deficient mice. Journal of Immunology 198 (1): 119\u2013127. doi:\n10.4049\/jimmunol.1600506\n\n.","journal-title":"Journal of Immunology"},{"issue":"8","key":"582_CR19","doi-asserted-by":"publisher","first-page":"F939","DOI":"10.1152\/ajprenal.00025.2013","volume":"307","author":"A Leelahavanichkul","year":"2014","unstructured":"Leelahavanichkul, A., A.C. Souza, J.M. Street, V. Hsu, T. Tsuji, K. Doi, L. Li, et al. 2014. Comparison of serum creatinine and serum cystatin C as biomarkers to detect sepsis-induced acute kidney injury and to predict mortality in CD-1 mice. American Journal of Physiology. Renal Physiology 307 (8): F939\u2013F948. doi:\n10.1152\/ajprenal.00025.2013\n\n.","journal-title":"American Journal of Physiology. Renal Physiology"},{"issue":"7","key":"582_CR20","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1038\/sj.gt.3300947","volume":"6","author":"F Liu","year":"1999","unstructured":"Liu, F., Y. Song, and D. Liu. 1999. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene Therapy 6 (7): 1258\u20131266. doi:\n10.1038\/sj.gt.3300947\n\n.","journal-title":"Gene Therapy"},{"issue":"4","key":"582_CR21","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1038\/leu.2014.310","volume":"29","author":"Y Liu","year":"2015","unstructured":"Liu, Y., Y. Wu, Y. Wang, Y. Cai, B. Hu, G. Bao, H. Fang, et al. 2015. IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects. Leukemia 29 (4): 939\u2013946. doi:\n10.1038\/leu.2014.310\n\n.","journal-title":"Leukemia"},{"key":"582_CR22","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201646493","author":"F Manzoor","year":"2016","unstructured":"Manzoor, F., M.C. Johnson, C. Li, R.J. Samulski, B. Wang, and R. Tisch. 2016. Beta-cell-specific IL-35 therapy suppresses ongoing autoimmune diabetes in NOD mice. European Journal of Immunology. doi:\n10.1002\/eji.201646493\n\n.","journal-title":"European Journal of Immunology"},{"issue":"2","key":"582_CR23","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/oxfordjournals.ndt.a027256","volume":"11","author":"H Neveu","year":"1996","unstructured":"Neveu, H., D. Kleinknecht, F. Brivet, P. Loirat, and P. Landais. 1996. Prognostic factors in acute renal failure due to sepsis. Results of a prospective multicentre study. The French study group on acute renal failure. Nephrology, Dialysis, Transplantation 11 (2): 293\u2013299.","journal-title":"Nephrology, Dialysis, Transplantation"},{"issue":"11","key":"582_CR24","doi-asserted-by":"publisher","first-page":"3021","DOI":"10.1002\/eji.200737810","volume":"37","author":"W Niedbala","year":"2007","unstructured":"Niedbala, W., X.Q. Wei, B. Cai, A.J. Hueber, B.P. Leung, I.B. McInnes, and F.Y. Liew. 2007. IL-35 is a novel cytokine with therapeutic effects against collagen-induced arthritis through the expansion of regulatory T cells and suppression of Th17 cells. European Journal of Immunology 37 (11): 3021\u20133029. doi:\n10.1002\/eji.200737810\n\n.","journal-title":"European Journal of Immunology"},{"issue":"1","key":"582_CR25","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.mvr.2008.09.001","volume":"77","author":"JD Paladino","year":"2009","unstructured":"Paladino, J.D., J.R. Hotchkiss, and H. Rabb. 2009. Acute kidney injury and lung dysfunction: a paradigm for remote organ effects of kidney disease? Microvascular Research 77 (1): 8\u201312. doi:\n10.1016\/j.mvr.2008.09.001\n\n.","journal-title":"Microvascular Research"},{"issue":"4","key":"582_CR26","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1038\/nrneph.2013.282","volume":"10","author":"O Rewa","year":"2014","unstructured":"Rewa, O., and S.M. Bagshaw. 2014. Acute kidney injury-epidemiology, outcomes and economics. Nature Reviews. Nephrology 10 (4): 193\u2013207. doi:\n10.1038\/nrneph.2013.282\n\n.","journal-title":"Nature Reviews. Nephrology"},{"issue":"10","key":"582_CR27","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1038\/nrneph.2016.113","volume":"12","author":"JC Schefold","year":"2016","unstructured":"Schefold, J.C., G. Filippatos, G. Hasenfuss, S.D. Anker, and S. von Haehling. 2016. Heart failure and kidney dysfunction: epidemiology, mechanisms and management. Nature Reviews. Nephrology 12 (10): 610\u2013623. doi:\n10.1038\/nrneph.2016.113\n\n.","journal-title":"Nature Reviews. Nephrology"},{"issue":"45","key":"582_CR28","doi-asserted-by":"crossref","first-page":"31868","DOI":"10.1074\/jbc.274.45.31868","volume":"274","author":"AJ Schottelius","year":"1999","unstructured":"Schottelius, A.J., M.W. Mayo, R.B. Sartor, and A.S. Baldwin Jr. 1999. Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA binding. The Journal of Biological Chemistry 274 (45): 31868\u201331874.","journal-title":"The Journal of Biological Chemistry"},{"issue":"5","key":"582_CR29","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1159\/000369141","volume":"76","author":"H Shen","year":"2014","unstructured":"Shen, H., C. Wang, E. Fan, Y. Li, W. Zhang, and L. Zhang. 2014. Upregulation of interleukin-35 subunits in regulatory T cells in a murine model of allergic rhinitis. ORL: Journal for Otorhinolaryngology and Its Related Specialties 76 (5): 237\u2013247. doi:\n10.1159\/000369141\n\n.","journal-title":"ORL: Journal for Otorhinolaryngology and Its Related Specialties"},{"issue":"7492","key":"582_CR30","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1038\/nature12979","volume":"507","author":"P Shen","year":"2014","unstructured":"Shen, P., T. Roch, V. Lampropoulou, R.A. O'Connor, U. Stervbo, E. Hilgenberg, S. Ries, et al. 2014. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature 507 (7492): 366\u2013370. doi:\n10.1038\/nature12979\n\n.","journal-title":"Nature"},{"issue":"10","key":"582_CR31","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1097\/00003246-200110000-00010","volume":"29","author":"W Silvester","year":"2001","unstructured":"Silvester, W., R. Bellomo, and L. Cole. 2001. Epidemiology, management, and outcome of severe acute renal failure of critical illness in Australia. Critical Care Medicine 29 (10): 1910\u20131915.","journal-title":"Critical Care Medicine"},{"issue":"4","key":"582_CR32","doi-asserted-by":"publisher","first-page":"1157","DOI":"10.1093\/ndt\/gfn626","volume":"24","author":"S Song","year":"2009","unstructured":"Song, S., M. Meyer, T.R. Turk, B. Wilde, T. Feldkamp, R. Assert, K. Wu, A. Kribben, and O. Witzke. 2009. Serum cystatin C in mouse models: a reliable and precise marker for renal function and superior to serum creatinine. Nephrology, Dialysis, Transplantation 24 (4): 1157\u20131161. doi:\n10.1093\/ndt\/gfn626\n\n.","journal-title":"Nephrology, Dialysis, Transplantation"},{"issue":"9","key":"582_CR33","doi-asserted-by":"publisher","first-page":"1482","DOI":"10.2215\/CJN.00710113","volume":"8","author":"P Susantitaphong","year":"2013","unstructured":"Susantitaphong, P., D.N. Cruz, J. Cerda, M. Abulfaraj, F. Alqahtani, I. Koulouridis, B.L. Jaber, and Nephrology Acute Kidney Injury Advisory Group of the American Society of. 2013. World incidence of AKI: a meta-analysis. Clinical Journal of the American Society of Nephrology 8 (9): 1482\u20131493. doi:\n10.2215\/CJN.00710113\n\n.","journal-title":"Clinical Journal of the American Society of Nephrology"},{"key":"582_CR34","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.cyto.2016.12.011","volume":"91","author":"M Tarique","year":"2016","unstructured":"Tarique, M., C. Saini, R.A. Naqvi, N. Khanna, and D.N. Rao. 2016. Increased IL-35 producing Tregs and CD19+IL-35+ cells are associated with disease progression in leprosy patients. Cytokine 91: 82\u201388. doi:\n10.1016\/j.cyto.2016.12.011\n\n.","journal-title":"Cytokine"},{"issue":"2","key":"582_CR35","doi-asserted-by":"publisher","first-page":"316","DOI":"10.1016\/j.immuni.2016.01.013","volume":"44","author":"ME Turnis","year":"2016","unstructured":"Turnis, M.E., D.V. Sawant, A.L. Szymczak-Workman, L.P. Andrews, G.M. Delgoffe, H. Yano, A.J. Beres, P. Vogel, C.J. Workman, and D.A. Vignali. 2016. Interleukin-35 limits anti-tumor immunity. Immunity 44 (2): 316\u2013329. doi:\n10.1016\/j.immuni.2016.01.013\n\n.","journal-title":"Immunity"},{"issue":"7","key":"582_CR36","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1001\/jama.294.7.813","volume":"294","author":"S Uchino","year":"2005","unstructured":"Uchino, S., J.A. Kellum, R. Bellomo, G.S. Doig, H. Morimatsu, S. Morgera, M. Schetz, et al. 2005. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294 (7): 813\u2013818. doi:\n10.1001\/jama.294.7.813\n\n.","journal-title":"JAMA"},{"issue":"1","key":"582_CR37","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1038\/ki.2013.286","volume":"85","author":"C Xu","year":"2014","unstructured":"Xu, C., A. Chang, B.K. Hack, M.T. Eadon, S.L. Alper, and P.N. Cunningham. 2014. TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis. Kidney International 85 (1): 72\u201381. doi:\n10.1038\/ki.2013.286\n\n.","journal-title":"Kidney International"},{"issue":"24","key":"582_CR38","doi-asserted-by":"publisher","first-page":"7274","DOI":"10.1158\/0008-5472.CAN-14-1091","volume":"74","author":"J Yang","year":"2014","unstructured":"Yang, J., O.E. Hawkins, W. Barham, P. Gilchuk, M. Boothby, G.D. Ayers, S. Joyce, M. Karin, F.E. Yull, and A. Richmond. 2014. Myeloid IKKbeta promotes antitumor immunity by modulating CCL11 and the innate immune response. Cancer Research 74 (24): 7274\u20137284. doi:\n10.1158\/0008-5472.CAN-14-1091\n\n.","journal-title":"Cancer Research"},{"issue":"6","key":"582_CR39","doi-asserted-by":"publisher","first-page":"999","DOI":"10.1681\/ASN.2010050484","volume":"22","author":"A Zarjou","year":"2011","unstructured":"Zarjou, A., and A. Agarwal. 2011. Sepsis and acute kidney injury. Journal of the American Society of Nephrology 22 (6): 999\u20131006. doi:\n10.1681\/ASN.2010050484\n\n.","journal-title":"Journal of the American Society of Nephrology"},{"key":"582_CR40","doi-asserted-by":"publisher","first-page":"21348","DOI":"10.1038\/srep21348","volume":"6","author":"F Zhang","year":"2016","unstructured":"Zhang, F., M.Y. Li, Y.T. Lan, and C.B. Wang. 2016. Imbalance of Th17\/Tregs in rats with smoke inhalation-induced acute lung injury. Scientific Reports 6: 21348. doi:\n10.1038\/srep21348\n\n.","journal-title":"Scientific Reports"},{"key":"582_CR41","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2016.12.001","author":"N Zhao","year":"2016","unstructured":"Zhao, N., H. Li, Y. Yan, R. Jiang, and X. He. 2016. Mesenchymal stem cells overexpressing IL-35 effectively inhibit CD4+ T cell function. Cellular Immunology. doi:\n10.1016\/j.cellimm.2016.12.001\n\n.","journal-title":"Cellular Immunology"},{"key":"582_CR42","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1146\/annurev-med-050214-013407","volume":"67","author":"A Zuk","year":"2016","unstructured":"Zuk, A., and J.V. Bonventre. 2016. Acute kidney injury. Annual Review of Medicine 67: 293\u2013307. doi:\n10.1146\/annurev-med-050214-013407\n\n.","journal-title":"Annual Review of Medicine"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-017-0582-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-017-0582-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-017-0582-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T02:45:34Z","timestamp":1498877134000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-017-0582-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,11]]},"references-count":42,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["582"],"URL":"https:\/\/doi.org\/10.1007\/s10753-017-0582-9","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,11]]}}}