{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T02:48:39Z","timestamp":1768790919779,"version":"3.49.0"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2019,3,16]],"date-time":"2019-03-16T00:00:00Z","timestamp":1552694400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Capes","doi-asserted-by":"crossref","award":["2764\/2011"],"award-info":[{"award-number":["2764\/2011"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s10753-019-00966-7","type":"journal-article","created":{"date-parts":[[2019,3,16]],"date-time":"2019-03-16T03:03:11Z","timestamp":1552705391000},"page":"1045-1055","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Anti-inflammatory Activity of Methanolic Extract and an Alkaloid from Palicourea crocea (Sw.) Roem and Schult"],"prefix":"10.1007","volume":"42","author":[{"given":"Anelise Samara Nazari","family":"Formagio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Cruz","family":"de Oliveira Junior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carla Roberta Ferreira","family":"Volobuff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Candida Aparecida Leite","family":"Kassuya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego Cegobia","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia Andrea Lima","family":"Cardoso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Helena","family":"Sarragiotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zefa Valdevina","family":"Pereira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,16]]},"reference":[{"key":"966_CR1","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.jep.2017.04.023.","volume":"9","author":"RV Ribeiro","year":"2017","unstructured":"Ribeiro, R.V., I.G.C. Bieski, S.O. Balogun, and D.T.O. Martins. 2017. Ethnobotanical study of medicinal plants used by Ribeirinhos in the North Araguaia microregion, Mato Grosso, Brazil. Journal of Ethnopharmacology 9: 69\u2013102. \nhttps:\/\/doi.org\/10.1016\/j.jep.2017.04.023.","journal-title":"Journal of Ethnopharmacology"},{"key":"966_CR2","unstructured":"Andrade, S.O., and Jr Matos. 1968. Contribui\u00e7\u00e3o do estudo de plantas t\u00f3xicas no Estado de S\u00e3o Paulo. Instituto Biol\u00f3gico: 63\u201366."},{"key":"966_CR3","first-page":"117","volume":"7","author":"PV Peixoto","year":"1987","unstructured":"Peixoto, P.V., J. D\u00f6bereiner, C.H. Tokarnia, and C.S. Peixoto. 1987. Intoxica\u00e7\u00e3o experimental por Palicourea marcgravii (Rubiaceae) em coelhos. Pesquisa Veterin\u00e1ria Brasileira 7: 117\u2013129.","journal-title":"Pesquisa Veterin\u00e1ria Brasileira"},{"key":"966_CR4","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1590\/S0100-67622003000600002","volume":"27","author":"ZV Pereira","year":"2003","unstructured":"Pereira, Z.V., R.M.S.A. Meira, and A.A. Azevedo. 2003. Morfoanatomia foliar de Palicourea longepedunculata Gardiner (Rubiaceae). Revista \u00c1rvore 27: 759\u2013767. \nhttps:\/\/doi.org\/10.1590\/S0100-67622003000600002\n\n.","journal-title":"Revista \u00c1rvore"},{"key":"966_CR5","volume-title":"Plantas T\u00f3xicas da Amaz\u00f4nia a Bovinos e outros Herb\u00edvoros","author":"CH Tokarnia","year":"1979","unstructured":"Tokarnia, C.H., J. Dobereiner, and M.F. Silva. 1979. Plantas T\u00f3xicas da Amaz\u00f4nia a Bovinos e outros Herb\u00edvoros. Manaus: INPA 95p."},{"key":"966_CR6","unstructured":"Afonso, E., Pott, A. 2001. Plantas no Pantanal T\u00f3xicas para Bovinos. Embrapa Informa\u00e7\u00e3o Tecnol\u00f3gica 51p. \nhttp:\/\/old.cnpgc.embrapa.br\/publicacoes\/livros\/plantastoxicas\/05suspeitas.html\n\n. Access 21 Aug 2018."},{"issue":"3","key":"966_CR7","first-page":"216","volume":"34","author":"SL Gorniak","year":"1992","unstructured":"Gorniak, S.L., N.J. Palermo, G.H. Oliveira, and H.S. Spinosa. 1992. Palicourea marcgravii intoxication in rats: effects of different fractions. Veterinary and Human Toxicology 34 (3): 216\u2013218.","journal-title":"Veterinary and Human Toxicology"},{"key":"966_CR8","unstructured":"Tokarnia, C.H., D\u00f6bereiner, J. Peixoto, P.V. 2000. Plantas t\u00f3xicas do Brasil. Embrapa. Rio de Janeiro ed. Helianthus. 310p."},{"key":"966_CR9","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1515\/znc-1996-1-211.","volume":"51","author":"W Kemmerling","year":"1996","unstructured":"Kemmerling, W. 1996. Toxicity of Palicourea marcgravii: combined effects of fluoroacetate, N-methyltyramine and 2-methyltetrahydro-beta-carboline. Zeitschrift f\u00fcr Naturforschung C A Journal of Biosciences 51: 59\u201364. \nhttps:\/\/doi.org\/10.1515\/znc-1996-1-211.","journal-title":"Zeitschrift f\u00fcr Naturforschung C A Journal of Biosciences"},{"key":"966_CR10","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1007\/BF02151004","volume":"19","author":"MM Oliveira","year":"1963","unstructured":"Oliveira, M.M. 1963. Chromatographic isolation of monofluoroacetic acid from Palicourea marcgravii St. Hil. Experientia 19: 586\u2013587.","journal-title":"Experientia"},{"key":"966_CR11","first-page":"685","volume":"28","author":"RL Moraes-Moreau","year":"1995","unstructured":"Moraes-Moreau, R.L., M. Haraguchi, H. Morita, and N.J. Palermo. 1995. Chemical and biological demonstration of the presence of mono-fluoroacetate in the leaves of Palicourea marcgravii St. Hil. Brazilian Journal of Medical and Biological Research 28: 685\u2013692.","journal-title":"Brazilian Journal of Medical and Biological Research"},{"key":"966_CR12","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1016\/j.toxicon.2012.05.029","volume":"60","author":"ST Lee","year":"2012","unstructured":"Lee, S.T., D. Cook, F. Riet-Correa, J.A. Pfister, W.R. Anderson, F.G. Lima, and D.R. Gardner. 2012. Detection of monofluoracetate in Palicourea and Amorimia species. Toxicon 60: 791\u2013796. \nhttps:\/\/doi.org\/10.1016\/j.toxicon.2012.05.029\n\n.","journal-title":"Toxicon"},{"key":"966_CR13","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1021\/np0340807","volume":"67","author":"LT D\u00fcsman","year":"2004","unstructured":"D\u00fcsman, L.T., T.C.M. Jorge, M.C. de Souza, M.N. Eberlin, E.C. Meurer, C.C. Bocca, E.A. Basso, and M.H. Sarragiotto. 2004. Monoterpene Indole alkaloids from Palicourea crocea. Journal of Natural Products 67: 1886\u20131888. \nhttps:\/\/doi.org\/10.1021\/np0340807\n\n.","journal-title":"Journal of Natural Products"},{"key":"966_CR14","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1021\/np0340807.","volume":"2","author":"LL Narine","year":"2009","unstructured":"Narine, L.L., and A.R. Maxwell. 2009. Monoterpenoid indole alkaloids from Palicourea crocea. Phytochemistry Letters 2: 34\u201336. \nhttps:\/\/doi.org\/10.1021\/np0340807.","journal-title":"Phytochemistry Letters"},{"key":"966_CR15","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1016\/j.phytochem.2015.05.013","volume":"116","author":"A Berger","year":"2015","unstructured":"Berger, A., M.K. Kostyan, S.I. Klose, M. Gastegger, E. Lorbeer, L. Brecker, and J. Schinnerl. 2015. Loganin and secologanin derived tryptamine\u2013iridoid alkaloids from Palicourea crocea and Palicourea padifolia (Rubiaceae). Phytochemistry 116: 162\u2013169. \nhttps:\/\/doi.org\/10.1016\/j.phytochem.2015.05.013\n\n.","journal-title":"Phytochemistry"},{"key":"966_CR16","first-page":"629","volume":"30","author":"ASN Formagio","year":"2014","unstructured":"Formagio, A.S.N., T.E. Masetto, M.C. Vieira, N.A.H. Z\u00e1rate, A.I.N. Matos, and C.R.F. Volobuff. 2014. Allelopathic and antioxidant potential of plants extracts. Journal of Biosciences 30: 629\u2013638.","journal-title":"Journal of Biosciences"},{"key":"966_CR17","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1590\/1808-1657000372013","volume":"82","author":"CS Zanella","year":"2015","unstructured":"Zanella, C.S., W.L. Gavassoni, L.M.A. Bacchi, and A.S.N. Formagio. 2015. Atividade de \u00f3leos e extratos vegetais sobre germina\u00e7\u00e3o carpog\u00eanica e crescimento micelial de Sclerotinia sclerotiorum. Arquivos do Instituto Biol\u00f3gico 82: 1\u20138. \nhttps:\/\/doi.org\/10.1590\/1808-1657000372013\n\n.","journal-title":"Arquivos do Instituto Biol\u00f3gico"},{"key":"966_CR18","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1042\/cs0470215.","volume":"47","author":"J Stocks","year":"1974","unstructured":"Stocks, J., J.M. Gutteridge, R.J. Sharp, and T.L. Dormandy. 1974. Assay using brain homogenate for measuring the antioxidant activity of biological fluids. Clinical Science and Molecular Medicine 47: 215\u2013222. \nhttps:\/\/doi.org\/10.1042\/cs0470215.","journal-title":"Clinical Science and Molecular Medicine"},{"key":"966_CR19","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3181\/00379727-111-27849.","volume":"111","author":"CA Winter","year":"1962","unstructured":"Winter, C.A., E.A. Risley, and G.W. Nuss. 1962. Carrageenin-induced edema in hind paw of the rat as an assay for anti-inflammatory drugs. Proceedings of the Society for Experimental Biology and Medicine 111: 544\u2013547. \nhttps:\/\/doi.org\/10.3181\/00379727-111-27849.","journal-title":"Proceedings of the Society for Experimental Biology and Medicine"},{"key":"966_CR20","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/0165-0270(94)90144-9","volume":"53","author":"SR Chaplan","year":"1994","unstructured":"Chaplan, S.R., F.W. Bach, J.W. Pogrel, J.M. Chung, and T.L. Yaksh. 1994. Quantitative assessment of tactile allodynia in the rat paw. Journal of Neuroscience Methods 53: 55\u201363. \nhttps:\/\/doi.org\/10.1016\/0165-0270(94)90144-9\n\n.","journal-title":"Journal of Neuroscience Methods"},{"key":"966_CR21","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0304-3959(00)00276-1.","volume":"87","author":"I Decosterd","year":"2000","unstructured":"Decosterd, I., and C.J. Woolf. 2000. Spared nerve injury: an animal model of persistent peripheral neurophatic pain. Pain 87: 149\u2013158. \nhttps:\/\/doi.org\/10.1016\/S0304-3959(00)00276-1.","journal-title":"Pain"},{"key":"966_CR22","doi-asserted-by":"publisher","first-page":"711","DOI":"10.3181\/00379727-143-37397.","volume":"143","author":"R Vinegar","year":"1973","unstructured":"Vinegar, R., J.F. Traux, and J.L. Selph. 1973. Some quantitative temporal characteristic of carrageenin-induced pleurisy in the rat. Proceedings of the Society for Experimental Biology and Medicine 143: 711\u2013714. \nhttps:\/\/doi.org\/10.3181\/00379727-143-37397.","journal-title":"Proceedings of the Society for Experimental Biology and Medicine"},{"key":"966_CR23","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford, M.M. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72: 248\u2013254. \nhttps:\/\/doi.org\/10.1016\/0003-2697(76)90527-3\n\n.","journal-title":"Analytical Biochemistry"},{"key":"966_CR24","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1016\/S0031-9422(99)00215-0","volume":"52","author":"J Valverde","year":"1999","unstructured":"Valverde, J., G. Tamayo, and M. Hesse. 1999. \u03b2-Carboline monoterpenoid glucosides from Palicourea adusta. Phytochemistry 52: 1485\u20131489. \nhttps:\/\/doi.org\/10.1016\/S0031-9422(99)00215-0\n\n.","journal-title":"Phytochemistry"},{"key":"966_CR25","doi-asserted-by":"publisher","first-page":"1443","DOI":"10.1002\/chin.200713196","volume":"61","author":"CA Nascimento Do","year":"2006","unstructured":"Do Nascimento, C.A., M.S. Gomesa, L.M. Li\u00e3o, C.M.A. de Oliveira, L. Kato, C.C. da Silva, and C.M.A. Tanaka. 2006. Alkaloides from Palicourea coriacea (Cham.) K. Schum. Zeitschrift f\u00fcr Naturforschung. B, A Journal of Chemical Sciences 61: 1443\u20131446. \nhttps:\/\/doi.org\/10.1002\/chin.200713196\n\n.","journal-title":"Zeitschrift f\u00fcr Naturforschung. B, A Journal of Chemical Sciences"},{"key":"966_CR26","doi-asserted-by":"publisher","first-page":"1104","DOI":"10.1016\/j.carres.2008.01.032","volume":"343","author":"CA Nascimento Do","year":"2008","unstructured":"Do Nascimento, C.A., L.M. Li\u00e3o, L. Kato, C.C. da Silva, C.M.A. Tanaka, I.T.A. Schuquel, and C.M.A. de Oliveira. 2008. A tetrahydro-b-carboline trisaccharide from Palicourea coriacea (Cham.) K. Schum. Carbohydrate Research 343: 1104\u20131107. \nhttps:\/\/doi.org\/10.1016\/j.carres.2008.01.032\n\n.","journal-title":"Carbohydrate Research"},{"key":"966_CR27","doi-asserted-by":"publisher","first-page":"4798","DOI":"10.1016\/j.tetlet.2014.06.090","volume":"55","author":"VA Kerber","year":"2014","unstructured":"Kerber, V.A., C.S. Passos, L.C.K. Junior, J.C. Quirion, X. Pannecoucke, I.S. Maire, and A.T. Henriques. 2014. Three new monoterpene indole alkaloids from Psychotria umbellata Thonn. Tetrahedron Letters 55: 4798\u20134800. \nhttps:\/\/doi.org\/10.1016\/j.tetlet.2014.06.090\n\n.","journal-title":"Tetrahedron Letters"},{"key":"966_CR28","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1016\/j.phytol.2012.05.013","volume":"5","author":"A Berger","year":"2012","unstructured":"Berger, A., H. Fasshuber, J. Schinnerl, L. Brecker, and H. Greger. 2012. Various types of tryptamine-iridoid alkaloids from Palicourea acuminata (=Psychotria acuminata, Rubiaceae). Phytochemistry Letters 5: 558\u2013562. \nhttps:\/\/doi.org\/10.1016\/j.phytol.2012.05.013\n\n.","journal-title":"Phytochemistry Letters"},{"key":"966_CR29","unstructured":"Bruneton, J. 1991. Elementos de Fitoqu\u00edmica y de Farmacognosia. AS\/Espanha: Ed. Acribia. 594p."},{"key":"966_CR30","doi-asserted-by":"publisher","first-page":"2058","DOI":"10.1016\/j.phytochem.2006.07.002","volume":"67","author":"A Seyoum","year":"2006","unstructured":"Seyoum, A., K. Asres, and F.K. El-Fiky. 2006. Structure\u2013radical scavenging activity relationships of flavonoids. Phytochemistry 67: 2058\u20132070. \nhttps:\/\/doi.org\/10.1016\/j.phytochem.2006.07.002\n\n.","journal-title":"Phytochemistry"},{"key":"966_CR31","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.tifs.2017.07.008","volume":"67","author":"B Gull\u00f3n","year":"2017","unstructured":"Gull\u00f3n, B., T.A.L. Chau, M.T. Moreira, J.M. Lema, and G. Eibes. 2017. Rutin: a review on extraction, identification and purification methods, biological activities and approaches to enhance its bioavailability. Trends in Food Science & Technology 67: 220\u2013235. \nhttps:\/\/doi.org\/10.1016\/j.tifs.2017.07.008\n\n.","journal-title":"Trends in Food Science & Technology"},{"key":"966_CR32","doi-asserted-by":"publisher","first-page":"1063","DOI":"10.1517\/13543784.2013.805744","volume":"22","author":"S Sharma","year":"2013","unstructured":"Sharma, S., A. Ali, J. Ali, J.K. Sahni, and S. Baboota. 2013. Rutin: therapeutic potential and recent advances in drug delivery. Expert Opinion on Investigational Drugs 22: 1063\u20131079. \nhttps:\/\/doi.org\/10.1517\/13543784.2013.805744\n\n.","journal-title":"Expert Opinion on Investigational Drugs"},{"key":"966_CR33","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/S0014-5793(97)00467-5","volume":"409","author":"C Manach","year":"1997","unstructured":"Manach, C., C. Morand, C. Demign\u00e9, O. Texier, F. R\u00e9g\u00e9rat, and C. R\u00e9m\u00e9sy. 1997. Bioavailability of rutin and quercetin in rats. FEBS Letters 409: 12\u201316. \nhttps:\/\/doi.org\/10.1016\/S0014-5793(97)00467-5\n\n.","journal-title":"FEBS Letters"},{"key":"966_CR34","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3164\/jcbn.40.92.","volume":"40","author":"M Srinivasan","year":"2007","unstructured":"Srinivasan, M., A.R. Sudheer, and V.P. Menon. 2007. Ferulic acid: therapeutic potential through its antioxidant property. Journal of Clinical Biochemistry and Nutrition 40: 92\u2013100. \nhttps:\/\/doi.org\/10.3164\/jcbn.40.92.","journal-title":"Journal of Clinical Biochemistry and Nutrition"},{"issue":"8","key":"966_CR35","doi-asserted-by":"publisher","first-page":"695","DOI":"10.2174\/138955711796268750","volume":"11","author":"M Touaibia","year":"2011","unstructured":"Touaibia, M., J. Jean-Fran\u00e7ois, and J. Doiron. 2011. Caffeic acid, a versatile pharmacophore: an overview. Mini-Reviews in Medicinal Chemistry 11 (8): 695\u2013713. \nhttps:\/\/doi.org\/10.2174\/138955711796268750\n\n.","journal-title":"Mini-Reviews in Medicinal Chemistry"},{"key":"966_CR36","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.tox.2005.09.011","volume":"217","author":"G Ilhami","year":"2006","unstructured":"Ilhami, G. 2006. Antioxidant activity of caffeic acid (3,4-dihydroxycinnamic acid). Toxicology 217: 213\u2013220. \nhttps:\/\/doi.org\/10.1016\/j.tox.2005.09.011\n\n.","journal-title":"Toxicology"},{"key":"966_CR37","doi-asserted-by":"publisher","first-page":"1456","DOI":"10.1016\/S0891-5849(00)00252-5","volume":"28","author":"K Hensley","year":"2000","unstructured":"Hensley, K., K.A. Robinson, S.P. Gabbita, S. Salsman, and R.A. Floyd. 2000. Reactive oxygen species, cell signaling and cell injury. Free Radical Biology & Medicine 28: 1456\u20131462. \nhttps:\/\/doi.org\/10.1016\/S0891-5849(00)00252-5\n\n.","journal-title":"Free Radical Biology & Medicine"},{"key":"966_CR38","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/AIA.0b013e318034194e","volume":"45","author":"JM Zhang","year":"2007","unstructured":"Zhang, J.M., and J. An. 2007. Cytokines, inflammation and pain. International Anesthesiology Clinics 45: 27\u201337. \nhttps:\/\/doi.org\/10.1097\/AIA.0b013e318034194e\n\n.","journal-title":"International Anesthesiology Clinics"},{"key":"966_CR39","doi-asserted-by":"publisher","first-page":"2062","DOI":"10.1021\/np200232s","volume":"74","author":"CM Oliveira De","year":"2011","unstructured":"De Oliveira, C.M., F.R. Nonato, F.O. de Lima, R.D. Couto, J.P. David, J.M. David, M.B. Soares, and C.F. Villarreal. 2011. Antinociceptive properties of bergenin. Journal of Natural Products 74: 2062\u20132068. \nhttps:\/\/doi.org\/10.1021\/np200232s\n\n.","journal-title":"Journal of Natural Products"},{"key":"966_CR40","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/path.1711040103","volume":"104","author":"M Rosa Di","year":"1971","unstructured":"Di Rosa, M., J.P. Giroud, and D.A. Willoughby. 1971. Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. The Journal of Pathology 104: 15\u201344. \nhttps:\/\/doi.org\/10.1002\/path.1711040103\n\n.","journal-title":"The Journal of Pathology"},{"key":"966_CR41","doi-asserted-by":"publisher","first-page":"336","DOI":"10.1076\/phbi.40.5.336.8453","volume":"40","author":"FL Both","year":"2002","unstructured":"Both, F.L., V.A. Kerber, A.T. Henriques, and E. Elisabetsky. 2002. Analgesic properties of umbellatine from Psychotria umbellata. Pharmaceutical Biology 40: 336\u2013341. \nhttps:\/\/doi.org\/10.1076\/phbi.40.5.336.8453\n\n.","journal-title":"Pharmaceutical Biology"},{"key":"966_CR42","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1021\/np049695y","volume":"68","author":"FL Both","year":"2005","unstructured":"Both, F.L., L. Meneghini, V.A. Kerber, A.T. Henriques, and E. Elisabetsky. 2005. Psychopharmacological profile of the alkaloid psychollatine as a 5HT2A\/C serotonina modulator. Journal of Natural Products 68: 374\u2013380. \nhttps:\/\/doi.org\/10.1021\/np049695y\n\n.","journal-title":"Journal of Natural Products"},{"key":"966_CR43","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1021\/np050291v","volume":"69","author":"FL Both","year":"2006","unstructured":"Both, F.L., L. Meneghini, V.A. Kerber, A.T. Henriques, and E. Elisabetsky. 2006. Role of glutamate and dopamine receptors in the psychopharmacological profile of the \u00edndole alkaloid psychollatine. Journal of Natural Products 69: 342\u2013345. \nhttps:\/\/doi.org\/10.1021\/np050291v\n\n.","journal-title":"Journal of Natural Products"},{"key":"966_CR44","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1016\/j.phytochem.2012.11.015","volume":"86","author":"CS Passos","year":"2013","unstructured":"Passos, C.S., C.A. Sim\u00f5es-Pires, A. Nurisso, T.C. Soldi, L. Kato, C.M. de Oliveira, E.O. de Faria, L. Marcourt, C. Gottfried, P.A. Carrupt, and A.T. Henriques. 2013. Indole alkaloids of Psychotria as multifunctional cholinesterase and monoamine oxidases inhibitors. Phytochemistry 86: 8\u201320. \nhttps:\/\/doi.org\/10.1016\/j.phytochem.2012.11.015\n\n.","journal-title":"Phytochemistry"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-019-00966-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-019-00966-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-019-00966-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,3,15]],"date-time":"2020-03-15T00:12:10Z","timestamp":1584231130000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-019-00966-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,16]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["966"],"URL":"https:\/\/doi.org\/10.1007\/s10753-019-00966-7","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,16]]},"assertion":[{"value":"16 March 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This work was found to comply with the ethical concepts required by the National Council for Animal Experiments Control (CONCEA), with current legislation and other provisions of the ethics investigations that directly involve the use of animals and all protocols and procedures were approved according to the Ethics Committee on Animal Use the Federal University of Grande Dourados, Mato Grosso do Sul, Brazil (CEUA\/UFGD) with authorization number 17\/2017.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}