{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T22:45:45Z","timestamp":1773528345737,"version":"3.50.1"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,3,2]],"date-time":"2019-03-02T00:00:00Z","timestamp":1551484800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100007847","name":"Jilin Province Natural Science Foundation","doi-asserted-by":"crossref","award":["D5111223428"],"award-info":[{"award-number":["D5111223428"]}],"id":[{"id":"10.13039\/100007847","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s10753-019-00993-4","type":"journal-article","created":{"date-parts":[[2019,3,2]],"date-time":"2019-03-02T01:58:52Z","timestamp":1551491932000},"page":"1326-1335","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Amelioration of Lipopolysaccharide-Induced Nephrotic Proteinuria by NFAT5 Depletion Involves Suppressed NF-\u03baB Activity"],"prefix":"10.1007","volume":"42","author":[{"given":"Shubo","family":"Zhai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meina","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baichao","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanyan","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,3,2]]},"reference":[{"issue":"1","key":"993_CR1","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1038\/s41467-017-00498-4","volume":"8","author":"M Liu","year":"2017","unstructured":"Liu, M., K. Liang, J. Zhen, M. Zhou, X. Wang, Z. Wang, X. Wei, Y. Zhang, Y. Sun, Z. Zhou, H. Su, C. Zhang, N. Li, C. Gao, J. Peng, and F. Yi. 2017. Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling. Nature Communications 8 (1): 413. \n                    https:\/\/doi.org\/10.1038\/s41467-017-00498-4\n                    \n                  .","journal-title":"Nature Communications"},{"issue":"10141","key":"993_CR2","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1016\/S0140-6736(18)30536-1","volume":"392","author":"DG Noone","year":"2018","unstructured":"Noone, D.G., K. Iijima, and R. Parekh. 2018. Idiopathic nephrotic syndrome in children. Lancet 392 (10141): 61\u201374. \n                    https:\/\/doi.org\/10.1016\/S0140-6736(18)30536-1\n                    \n                  .","journal-title":"Lancet"},{"issue":"4","key":"993_CR3","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1007\/s10157-003-0259-6","volume":"7","author":"K Asanuma","year":"2003","unstructured":"Asanuma, K., and P. Mundel. 2003. The role of podocytes in glomerular pathobiology. Clinical and Experimental Nephrology 7 (4): 255\u2013259. \n                    https:\/\/doi.org\/10.1007\/s10157-003-0259-6\n                    \n                  .","journal-title":"Clinical and Experimental Nephrology"},{"issue":"12","key":"993_CR4","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1038\/sj.ki.5002222","volume":"71","author":"RC Wiggins","year":"2007","unstructured":"Wiggins, R.C. 2007. The spectrum of podocytopathies: a unifying view of glomerular diseases. Kidney International 71 (12): 1205\u20131214. \n                    https:\/\/doi.org\/10.1038\/sj.ki.5002222\n                    \n                  .","journal-title":"Kidney International"},{"issue":"2","key":"993_CR5","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1046\/j.1523-1755.2001.059002415.x","volume":"59","author":"C Guijarro","year":"2001","unstructured":"Guijarro, C., and J. Egido. 2001. Transcription factor-kappa B (NF-kappa B) and renal disease. Kidney International 59 (2): 415\u2013424. \n                    https:\/\/doi.org\/10.1046\/j.1523-1755.2001.059002415.x\n                    \n                  .","journal-title":"Kidney International"},{"issue":"1\u20132","key":"993_CR6","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.cell.2016.12.012","volume":"168","author":"Q Zhang","year":"2017","unstructured":"Zhang, Q., M.J. Lenardo, and D. Baltimore. 2017. 30 years of NF-kappaB: a blossoming of relevance to human pathobiology. Cell 168 (1\u20132): 37\u201357. \n                    https:\/\/doi.org\/10.1016\/j.cell.2016.12.012\n                    \n                  .","journal-title":"Cell"},{"issue":"3","key":"993_CR7","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1046\/j.1523-1755.2001.059003923.x","volume":"59","author":"SJ Mudge","year":"2001","unstructured":"Mudge, S.J., K. Paizis, R.B. Auwardt, R.J. Thomas, and D.A. Power. 2001. Activation of nuclear factor-kappa B by podocytes in the autologous phase of passive Heymann nephritis. Kidney International 59 (3): 923\u2013931. \n                    https:\/\/doi.org\/10.1046\/j.1523-1755.2001.059003923.x\n                    \n                  .","journal-title":"Kidney International"},{"issue":"2","key":"993_CR8","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1007\/s00428-005-0061-9","volume":"448","author":"L Zheng","year":"2006","unstructured":"Zheng, L., R. Sinniah, and S.I. Hsu. 2006. In situ glomerular expression of activated NF-kappaB in human lupus nephritis and other non-proliferative proteinuric glomerulopathy. Virchows Archiv 448 (2): 172\u2013183. \n                    https:\/\/doi.org\/10.1007\/s00428-005-0061-9\n                    \n                  .","journal-title":"Virchows Archiv"},{"issue":"4","key":"993_CR9","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1159\/000348803","volume":"37","author":"T Shimo","year":"2013","unstructured":"Shimo, T., Y. Adachi, S. Yamanouchi, S. Tsuji, T. Kimata, K. Umezawa, M. Okigaki, J. Takaya, S. Ikehara, and K. Kaneko. 2013. A novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin, ameliorates puromycin aminonucleoside-induced nephrosis in mice. American Journal of Nephrology 37 (4): 302\u2013309. \n                    https:\/\/doi.org\/10.1159\/000348803\n                    \n                  .","journal-title":"American Journal of Nephrology"},{"issue":"1","key":"993_CR10","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1007\/s10157-016-1268-6","volume":"21","author":"M Yamashita","year":"2017","unstructured":"Yamashita, M., T. Yoshida, S. Suzuki, K. Homma, and M. Hayashi. 2017. Podocyte-specific NF-kappaB inhibition ameliorates proteinuria in adriamycin-induced nephropathy in mice. Clinical and Experimental Nephrology 21 (1): 16\u201326. \n                    https:\/\/doi.org\/10.1007\/s10157-016-1268-6\n                    \n                  .","journal-title":"Clinical and Experimental Nephrology"},{"issue":"1","key":"993_CR11","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/S1074-7613(01)00165-0","volume":"15","author":"C Lopez-Rodriguez","year":"2001","unstructured":"Lopez-Rodriguez, C., J. Aramburu, L. Jin, A.S. Rakeman, M. Michino, and A. Rao. 2001. Bridging the NFAT and NF-kappaB families: NFAT5 dimerization regulates cytokine gene transcription in response to osmotic stress. Immunity 15 (1): 47\u201358.","journal-title":"Immunity"},{"issue":"19","key":"993_CR12","doi-asserted-by":"publisher","first-page":"3459","DOI":"10.1091\/mbc.E10-02-0133","volume":"21","author":"I Roth","year":"2010","unstructured":"Roth, I., V. Leroy, H.M. Kwon, P.Y. Martin, E. Feraille, and U. Hasler. 2010. Osmoprotective transcription factor NFAT5\/TonEBP modulates nuclear factor-kappaB activity. Molecular Biology of the Cell 21 (19): 3459\u20133474. \n                    https:\/\/doi.org\/10.1091\/mbc.E10-02-0133\n                    \n                  .","journal-title":"Molecular Biology of the Cell"},{"issue":"7","key":"993_CR13","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1080\/02713683.2016.1270327","volume":"42","author":"I Chung","year":"2017","unstructured":"Chung, I., Y.S. Hah, S. Ju, J.H. Kim, W.S. Yoo, H.Y. Cho, J.M. Yoo, S.W. Seo, W.S. Choi, and S.J. Kim. 2017. Ultraviolet B radiation stimulates the interaction between nuclear factor of activated T cells 5 (NFAT5) and nuclear factor-kappa B (NF-kappaB) in human lens epithelial cells. Current Eye Research 42 (7): 987\u2013994. \n                    https:\/\/doi.org\/10.1080\/02713683.2016.1270327\n                    \n                  .","journal-title":"Current Eye Research"},{"issue":"6","key":"993_CR14","doi-asserted-by":"publisher","first-page":"5033","DOI":"10.3892\/mmr.2016.5860","volume":"14","author":"C Li","year":"2016","unstructured":"Li, C., M. Liu, L. Bo, W. Liu, Q. Liu, X. Chen, D. Xu, Z. Li, and F. Jin. 2016. NFAT5 participates in seawater inhalation induced acute lung injury via modulation of NF-kappaB activity. Molecular Medicine Reports 14 (6): 5033\u20135040. \n                    https:\/\/doi.org\/10.3892\/mmr.2016.5860\n                    \n                  .","journal-title":"Molecular Medicine Reports"},{"issue":"122","key":"993_CR15","doi-asserted-by":"publisher","first-page":"ra39","DOI":"10.1126\/scisignal.2000678","volume":"3","author":"SY Zhang","year":"2010","unstructured":"Zhang, S.Y., M. Kamal, K. Dahan, A. Pawlak, V. Ory, D. Desvaux, V. Audard, M. Candelier, F. BenMohamed, M. Matignon, C. Christov, X. Decrouy, V. Bernard, G. Mangiapan, P. Lang, G. Guellaen, P. Ronco, and D. Sahali. 2010. C-mip impairs podocyte proximal signaling and induces heavy proteinuria. Science Signaling 3 (122): ra39. \n                    https:\/\/doi.org\/10.1126\/scisignal.2000678\n                    \n                  .","journal-title":"Science Signaling"},{"issue":"1","key":"993_CR16","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s12079-012-0184-0","volume":"7","author":"T Srivastava","year":"2013","unstructured":"Srivastava, T., M. Sharma, K.H. Yew, R. Sharma, R.S. Duncan, M.A. Saleem, E.T. McCarthy, A. Kats, P.A. Cudmore, U.S. Alon, and C.J. Harrison. 2013. LPS and PAN-induced podocyte injury in an in vitro model of minimal change disease: changes in TLR profile. Journal of Cell Communication and Signaling 7 (1): 49\u201360. \n                    https:\/\/doi.org\/10.1007\/s12079-012-0184-0\n                    \n                  .","journal-title":"Journal of Cell Communication and Signaling"},{"issue":"1","key":"993_CR17","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1038\/nm1696","volume":"14","author":"C Wei","year":"2008","unstructured":"Wei, C., C.C. Moller, M.M. Altintas, J. Li, K. Schwarz, S. Zacchigna, L. Xie, A. Henger, H. Schmid, M.P. Rastaldi, P. Cowan, M. Kretzler, R. Parrilla, M. Bendayan, V. Gupta, B. Nikolic, R. Kalluri, P. Carmeliet, P. Mundel, and J. Reiser. 2008. Modification of kidney barrier function by the urokinase receptor. Nature Medicine 14 (1): 55\u201363. \n                    https:\/\/doi.org\/10.1038\/nm1696\n                    \n                  .","journal-title":"Nature Medicine"},{"issue":"3","key":"993_CR18","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1038\/ki.2014.71","volume":"86","author":"DV Ilatovskaya","year":"2014","unstructured":"Ilatovskaya, D.V., O. Palygin, V. Chubinskiy-Nadezhdin, Y.A. Negulyaev, R. Ma, L. Birnbaumer, and A. Staruschenko. 2014. Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli. Kidney International 86 (3): 506\u2013514. \n                    https:\/\/doi.org\/10.1038\/ki.2014.71\n                    \n                  .","journal-title":"Kidney International"},{"issue":"6","key":"993_CR19","doi-asserted-by":"publisher","first-page":"2473","DOI":"10.1111\/j.1523-1755.2005.00723.x","volume":"68","author":"RF Ransom","year":"2005","unstructured":"Ransom, R.F., N.G. Lam, M.A. Hallett, S.J. Atkinson, and W.E. Smoyer. 2005. Glucocorticoids protect and enhance recovery of cultured murine podocytes via actin filament stabilization. Kidney International 68 (6): 2473\u20132483. \n                    https:\/\/doi.org\/10.1111\/j.1523-1755.2005.00723.x\n                    \n                  .","journal-title":"Kidney International"},{"key":"993_CR20","doi-asserted-by":"publisher","first-page":"28282","DOI":"10.1038\/srep28282","volume":"6","author":"CM Borges","year":"2016","unstructured":"Borges, C.M., A. Papadimitriou, D.A. Duarte, J.M. Lopes de Faria, and J.B. Lopes de Faria. 2016. The use of green tea polyphenols for treating residual albuminuria in diabetic nephropathy: A double-blind randomised clinical trial. Scientific Reports 6: 28282. \n                    https:\/\/doi.org\/10.1038\/srep28282\n                    \n                  .","journal-title":"Scientific Reports"},{"issue":"2","key":"993_CR21","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1038\/nm0209-133a","volume":"15","author":"WD Comper","year":"2009","unstructured":"Comper, W.D. 2009. Is the LPS-mediated proteinuria mouse model relevant to human kidney disease? Nature Medicine 15 (2): 133; author reply 133-134. \n                    https:\/\/doi.org\/10.1038\/nm0209-133a\n                    \n                  .","journal-title":"Nature Medicine"},{"issue":"6368","key":"993_CR22","doi-asserted-by":"publisher","first-page":"1332","DOI":"10.1126\/science.aal4178","volume":"358","author":"Y Zhou","year":"2017","unstructured":"Zhou, Y., P. Castonguay, E.H. Sidhom, A.R. Clark, M. Dvela-Levitt, S. Kim, J. Sieber, N. Wieder, J.Y. Jung, S. Andreeva, J. Reichardt, F. Dubois, S.C. Hoffmann, J.M. Basgen, M.S. Montesinos, A. Weins, A.C. Johnson, E.S. Lander, M.R. Garrett, C.R. Hopkins, and A. Greka. 2017. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science 358 (6368): 1332\u20131336. \n                    https:\/\/doi.org\/10.1126\/science.aal4178\n                    \n                  .","journal-title":"Science"},{"issue":"4","key":"993_CR23","doi-asserted-by":"publisher","first-page":"e60546","DOI":"10.1371\/journal.pone.0060546","volume":"8","author":"L Fang","year":"2013","unstructured":"Fang, L., Y. Zhou, H. Cao, P. Wen, L. Jiang, W. He, C. Dai, and J. Yang. 2013. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS One 8 (4): e60546. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0060546\n                    \n                  .","journal-title":"PLoS One"},{"key":"993_CR24","doi-asserted-by":"publisher","first-page":"185","DOI":"10.1016\/j.freeradbiomed.2015.02.031","volume":"84","author":"AK Mashmoushi","year":"2015","unstructured":"Mashmoushi, A.K., and J.C. Oates. 2015. Lipopolysaccharide induces inducible nitric oxide synthase-dependent podocyte dysfunction via a hypoxia-inducible factor 1alpha and cell division control protein 42 and Ras-related C3 botulinum toxin substrate 1 pathway. Free Radical Biology & Medicine 84: 185\u2013195. \n                    https:\/\/doi.org\/10.1016\/j.freeradbiomed.2015.02.031\n                    \n                  .","journal-title":"Free Radical Biology & Medicine"},{"key":"993_CR25","doi-asserted-by":"publisher","first-page":"27589","DOI":"10.1038\/srep27589","volume":"6","author":"Y Qiao","year":"2016","unstructured":"Qiao, Y., A.L. Berg, P. Wang, Y. Ge, S. Quan, S. Zhou, H. Wang, Z. Liu, and R. Gong. 2016. MC1R is dispensable for the proteinuria reducing and glomerular protective effect of melanocortin therapy. Scientific Reports 6: 27589. \n                    https:\/\/doi.org\/10.1038\/srep27589\n                    \n                  .","journal-title":"Scientific Reports"},{"issue":"4","key":"993_CR26","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1046\/j.1523-1755.2001.00941.x","volume":"60","author":"SA Mezzano","year":"2001","unstructured":"Mezzano, S.A., M. Barria, M.A. Droguett, M.E. Burgos, L.G. Ardiles, C. Flores, and J. Egido. 2001. Tubular NF-kappaB and AP-1 activation in human proteinuric renal disease. Kidney International 60 (4): 1366\u20131377. \n                    https:\/\/doi.org\/10.1046\/j.1523-1755.2001.00941.x\n                    \n                  .","journal-title":"Kidney International"},{"issue":"8","key":"993_CR27","doi-asserted-by":"publisher","first-page":"1254","DOI":"10.1681\/ASN.2010020218","volume":"21","author":"AB Sanz","year":"2010","unstructured":"Sanz, A.B., M.D. Sanchez-Nino, A.M. Ramos, J.A. Moreno, B. Santamaria, M. Ruiz-Ortega, J. Egido, and A. Ortiz. 2010. NF-kappaB in renal inflammation. Journal of the American Society of Nephrology 21 (8): 1254\u20131262. \n                    https:\/\/doi.org\/10.1681\/ASN.2010020218\n                    \n                  .","journal-title":"Journal of the American Society of Nephrology"},{"issue":"5","key":"993_CR28","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1536\/ihj.51.348","volume":"51","author":"YS Kim","year":"2010","unstructured":"Kim, Y.S., J.S. Kim, J.S. Kwon, M.H. Jeong, J.G. Cho, J.C. Park, J.C. Kang, and Y. Ahn. 2010. BAY 11-7082, a nuclear factor-kappaB inhibitor, reduces inflammation and apoptosis in a rat cardiac ischemia-reperfusion injury model. International Heart Journal 51 (5): 348\u2013353.","journal-title":"International Heart Journal"},{"issue":"6","key":"993_CR29","doi-asserted-by":"publisher","first-page":"1221","DOI":"10.1016\/j.kint.2016.01.012","volume":"89","author":"M Nagata","year":"2016","unstructured":"Nagata, M. 2016. Podocyte injury and its consequences. Kidney International 89 (6): 1221\u20131230. \n                    https:\/\/doi.org\/10.1016\/j.kint.2016.01.012\n                    \n                  .","journal-title":"Kidney International"},{"issue":"4","key":"993_CR30","doi-asserted-by":"publisher","first-page":"F1141","DOI":"10.1152\/ajprenal.00288.2005","volume":"292","author":"S Ohga","year":"2007","unstructured":"Ohga, S., K. Shikata, K. Yozai, S. Okada, D. Ogawa, H. Usui, J. Wada, Y. Shikata, and H. Makino. 2007. Thiazolidinedione ameliorates renal injury in experimental diabetic rats through anti-inflammatory effects mediated by inhibition of NF-kappaB activation. American Journal of Physiology Renal Physiology 292 (4): F1141\u2013F1150. \n                    https:\/\/doi.org\/10.1152\/ajprenal.00288.2005\n                    \n                  .","journal-title":"American Journal of Physiology Renal Physiology"},{"issue":"2","key":"993_CR31","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1084\/jem.20111569","volume":"209","author":"M Buxade","year":"2012","unstructured":"Buxade, M., G. Lunazzi, J. Minguillon, S. Iborra, R. Berga-Bolanos, M. Del Val, J. Aramburu, and C. Lopez-Rodriguez. 2012. Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5. The Journal of Experimental Medicine 209 (2): 379\u2013393. \n                    https:\/\/doi.org\/10.1084\/jem.20111569\n                    \n                  .","journal-title":"The Journal of Experimental Medicine"},{"issue":"40","key":"993_CR32","doi-asserted-by":"publisher","first-page":"16091","DOI":"10.1073\/pnas.1215934110","volume":"110","author":"R Berga-Bolanos","year":"2013","unstructured":"Berga-Bolanos, R., M. Alberdi, M. Buxade, J. Aramburu, and C. Lopez-Rodriguez. 2013. NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte development. Proceedings of the National Academy of Sciences of the United States of America 110 (40): 16091\u201316096. \n                    https:\/\/doi.org\/10.1073\/pnas.1215934110\n                    \n                  .","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"13","key":"993_CR33","doi-asserted-by":"publisher","first-page":"7214","DOI":"10.1073\/pnas.96.13.7214","volume":"96","author":"C Lopez-Rodriguez","year":"1999","unstructured":"Lopez-Rodriguez, C., J. Aramburu, A.S. Rakeman, and A. Rao. 1999. NFAT5, a constitutively nuclear NFAT protein that does not cooperate with Fos and Jun. Proceedings of the National Academy of Sciences of the United States of America 96 (13): 7214\u20137219.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"10","key":"993_CR34","doi-asserted-by":"publisher","first-page":"F1473","DOI":"10.1152\/ajprenal.00031.2012","volume":"303","author":"S Brahler","year":"2012","unstructured":"Brahler, S., C. Ising, H. Hagmann, M. Rasmus, M. Hoehne, C. Kurschat, T. Kisner, H. Goebel, S. Shankland, K. Addicks, F. Thaiss, B. Schermer, M. Pasparakis, T. Benzing, and P.T. Brinkkoetter. 2012. Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. American Journal of Physiology Renal Physiology 303 (10): F1473\u2013F1485. \n                    https:\/\/doi.org\/10.1152\/ajprenal.00031.2012\n                    \n                  .","journal-title":"American Journal of Physiology Renal Physiology"},{"issue":"7","key":"993_CR35","doi-asserted-by":"publisher","first-page":"e19186","DOI":"10.1371\/journal.pone.0019186","volume":"6","author":"MC Mak","year":"2011","unstructured":"Mak, M.C., K.M. Lam, P.K. Chan, Y.B. Lau, W.H. Tang, P.K. Yeung, B.C. Ko, S.M. Chung, and S.K. Chung. 2011. Embryonic lethality in mice lacking the nuclear factor of activated T cells 5 protein due to impaired cardiac development and function. PLoS One 6 (7): e19186. \n                    https:\/\/doi.org\/10.1371\/journal.pone.0019186\n                    \n                  .","journal-title":"PLoS One"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-019-00993-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-019-00993-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-019-00993-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,29]],"date-time":"2020-02-29T19:11:44Z","timestamp":1583003504000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-019-00993-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,2]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["993"],"URL":"https:\/\/doi.org\/10.1007\/s10753-019-00993-4","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,2]]},"assertion":[{"value":"2 March 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"This study was approved by the Ethics Committee of The First Hospital of Jilin University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"The authors declare that they have no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}