{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T13:13:22Z","timestamp":1770902002045,"version":"3.50.1"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T00:00:00Z","timestamp":1556582400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81672093"],"award-info":[{"award-number":["81672093"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81770979"],"award-info":[{"award-number":["81770979"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012620","name":"Taishan Scholar Foundation of Shandong Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012620","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1007\/s10753-019-01000-6","type":"journal-article","created":{"date-parts":[[2019,4,30]],"date-time":"2019-04-30T13:33:28Z","timestamp":1556631208000},"page":"1389-1400","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Regulation of KDM2B and Brg1 on Inflammatory Response of Nasal Mucosa in CRSwNP"],"prefix":"10.1007","volume":"42","author":[{"given":"C. C.","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Q.","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F. L.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X. J.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X. X.","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2019,4,30]]},"reference":[{"key":"1000_CR1","unstructured":"Fokkens WJ, Lund VJ, Mullol J, Bachert C, Alobid I, Baroody F, et al. 2012. European position paper on rhinosinusitis and nasal polyps 2012. Rhinology Supplement 3. preceding table of contents, 1\u2013298."},{"key":"1000_CR2","first-page":"690","volume":"44","author":"PP Cao","year":"2014","unstructured":"Cao, P.P., Y.N. Zhang, B. Liao, et al. 2014. Increased local IgE production induced by common aeroallergens and phenotypic alteration of mast cells in Chinese eosinophilic, but not non-eosinophilic, chronic rhinosinusitis with nasal polyps. Allergy 44: 690\u2013700.","journal-title":"Allergy"},{"key":"1000_CR3","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1111\/j.1398-9995.2011.02637.x","volume":"66","author":"L Ba","year":"2011","unstructured":"Ba, L., N. Zhang, J. Meng, J. Zhang, P. Lin, P. Zhou, S. Liu, and C. Bachert. 2011. The association between bacterial colonization and inflammatory pattern in Chinese chronic rhinosinusitis patients with nasal polyps. Allergy 66: 1296\u20131303.","journal-title":"Allergy"},{"issue":"6","key":"1000_CR4","doi-asserted-by":"publisher","first-page":"549","DOI":"10.2500\/ajr.2008.22.3228","volume":"22","author":"RC Kern","year":"2008","unstructured":"Kern, R.C., D.B. Conley, W. Walsh, R. Chandra, A. Kato, A. Tripathi-Peters, et al. 2008. Perspectives on the etiology of chronic rhinosinusitis: an immune barrier hypothesis. American Journal of Rhinology 22 (6): 549\u2013559.","journal-title":"American Journal of Rhinology"},{"issue":"9","key":"1000_CR5","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.1111\/j.1398-9995.2008.01785.x","volume":"63","author":"AB Vroling","year":"2008","unstructured":"Vroling, A.B., W.J. Fokkens, and C.M. van Drunen. 2008. How epithelial cells detect danger: aiding the immune response. Allergy. 63 (9): 1110\u20131123.","journal-title":"Allergy."},{"issue":"6","key":"1000_CR6","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.1016\/j.jaci.2008.03.002","volume":"121","author":"A Kato","year":"2008","unstructured":"Kato, A., A. Peters, L. Suh, R. Carter, K.E. Harris, R. Chandra, et al. 2008. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. The Journal of Allergy and Clinical Immunology 121 (6): 1385\u20131392 92 e1\u20132.","journal-title":"The Journal of Allergy and Clinical Immunology"},{"key":"1000_CR7","volume-title":"Allergy and allergic diseases","author":"PC Avila","year":"2008","unstructured":"Avila, P.C., and R.P. Schleimer. 2008. Airway epithelium. In Allergy and allergic diseases, ed. A.B. Kay, A.P. Kaplan, J. Bousquet, and P.G. Holt, 2nd ed. Wiley-Blackwell: Hoboken.","edition":"2"},{"issue":"5","key":"1000_CR8","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1111\/j.1398-9995.2005.00753.x","volume":"60","author":"ML Kowalski","year":"2005","unstructured":"Kowalski, M.L., A. Lewandowska-Polak, J. Wozniak, A. Ptasinska, A. Jankowski, M. Wagrowska-Danilewicz, M. Danilewicz, and R. Pawliczak. 2005. Association of stem cell factor expression in nasal polyp epithelial cells with aspirin sensitivity and asthma. Allergy 60 (5): 631\u2013637.","journal-title":"Allergy"},{"issue":"4","key":"1000_CR9","first-page":"413","volume":"47","author":"Y Nishi","year":"2009","unstructured":"Nishi, Y., S. Takeno, T. Ishino, and K. Hirakawa. 2009. Glucocorticoids suppress NF-kappaB activation induced by LPS and PGN in paranasal sinus epithelial cells. Rhinology 47 (4): 413\u2013418.","journal-title":"Rhinology"},{"issue":"9","key":"1000_CR10","doi-asserted-by":"publisher","first-page":"e0161013","DOI":"10.1371\/journal.pone.0161013","volume":"11","author":"J Xu","year":"2016","unstructured":"Xu, J., R. Han, D.W. Kim, J.H. Mo, Y. Jin, K.S. Rha, and Y.M. Kim. 2016. Role of interleukin-10 on nasal polypogenesis in patients with chronic rhinosinusitis with nasal polyps. PLoS One 11 (9): e0161013.","journal-title":"PLoS One"},{"issue":"1","key":"1000_CR11","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1111\/j.1365-2222.2005.02403.x","volume":"36","author":"J Mullol","year":"2006","unstructured":"Mullol, J., J. Roca-Ferrer, I. Alobid, L. Pujols, A. Valero, A. Xaubet, M. Bernal-Sprekelsen, and C. Picado. 2006 Jan. Effect of desloratadine on epithelial cell granulocyte-macrophage colony- stimulating factor secretion and eosinophil survival. Clinical and Experimental Allergy. 36 (1): 52\u201358.","journal-title":"Clinical and Experimental Allergy."},{"issue":"2","key":"1000_CR12","doi-asserted-by":"crossref","first-page":"168","DOI":"10.4193\/Rhino10.099","volume":"49","author":"F Sachse","year":"2011","unstructured":"Sachse, F., K. Becker, T.J. Basel, D. Weiss, and C. Rudack. 2011. IKK-2 inhibitor TPCA-1 represses nasal epithelial inflammation in vitro. Rhinology. 49 (2): 168\u2013173.","journal-title":"Rhinology."},{"key":"1000_CR13","doi-asserted-by":"publisher","first-page":"545","DOI":"10.1146\/annurev.biochem.67.1.545","volume":"67","author":"JL Workman","year":"1998","unstructured":"Workman, J.L., and R.E. Kingston. 1998. Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annual Review of Biochemistry 67: 545\u2013579.","journal-title":"Annual Review of Biochemistry"},{"key":"1000_CR14","first-page":"143","volume":"274","author":"W Wang","year":"2003","unstructured":"Wang, W. 2003. The SWI\/SNF family of ATP-dependent chromatin remodelers: similar mechanisms for diverse functions. Current Topics in Microbiology and Immunology 274: 143\u2013169.","journal-title":"Current Topics in Microbiology and Immunology"},{"key":"1000_CR15","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1038\/nri1501","volume":"4","author":"T Chi","year":"2004","unstructured":"Chi, T. 2004. A BAF-centred view of the immune system. Nature Reviews. Immunology 4: 965\u2013977.","journal-title":"Nature Reviews. Immunology"},{"key":"1000_CR16","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1002\/cbic.201000455","volume":"12","author":"N Liu","year":"2011","unstructured":"Liu, N., A. Balliano, and J.J. Hayes. 2011. Mechanism(s) of SWI\/SNF-induced nucleosome mobilization. Chembiochem 12: 196\u2013204.","journal-title":"Chembiochem"},{"key":"1000_CR17","doi-asserted-by":"publisher","first-page":"1512","DOI":"10.1128\/MCB.00920-10","volume":"31","author":"S De","year":"2011","unstructured":"De, S., A.L. Wurster, P. Precht, W.H. Wood, K.G. Becker, and M.J. Pazin. 2011. Dynamic Brg1 recruitment during T helper differentiation and activation reveals distal regulatory elements. Molecular and Cellular Biology 31: 1512\u20131527.","journal-title":"Molecular and Cellular Biology"},{"key":"1000_CR18","doi-asserted-by":"publisher","first-page":"7274","DOI":"10.1128\/MCB.00835-08","volume":"28","author":"AL Wurster","year":"2008","unstructured":"Wurster, A.L., and M.J. Pazin. 2008. Brg1-mediated chromatin remodeling regulates differentiation and gene expression of T helper cells. Molecular and Cellular Biology 28: 7274\u20137285.","journal-title":"Molecular and Cellular Biology"},{"issue":"4","key":"1000_CR19","doi-asserted-by":"publisher","first-page":"a019521","DOI":"10.1101\/cshperspect.a019521","volume":"8","author":"JE Audia","year":"2016","unstructured":"Audia, J.E., and R.M. Campbell. 2016. Histone modifications and cancer. Cold Spring Harbor Perspectives in Biology 8 (4): a019521.","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"key":"1000_CR20","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1038\/ni.1619","volume":"9","author":"Z Ni","year":"2008","unstructured":"Ni, Z., M. Abou El Hassan, Z. Xu, T. Yu, and R. Bremner. 2008. The chromatin-remodeling enzyme Brg1 coordinates CIITA induction through many interdependent distal enhancers. Nature Immunology 9: 785\u2013793.","journal-title":"Nature Immunology"},{"key":"1000_CR21","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/ncb2483","volume":"14","author":"G Liang","year":"2012","unstructured":"Liang, G., J. He, and Y. Zhang. 2012. Kdm2b promotes induced pluripotent stem cell generation by facilitating gene activation early in reprogramming. Nature Cell Biology 14: 457\u2013466.","journal-title":"Nature Cell Biology"},{"key":"1000_CR22","doi-asserted-by":"publisher","first-page":"1169","DOI":"10.1038\/nsmb.1499","volume":"15","author":"J He","year":"2008","unstructured":"He, J., E.M. Kallin, Y. Tsukada, and Y. Zhang. 2008. The H3K36 demethylase Jhdm1b\/Kdm2b regulates cell proliferation and senescence through p15(Ink4b). Nature Structural & Molecular Biology 15: 1169\u20131175.","journal-title":"Nature Structural & Molecular Biology"},{"key":"1000_CR23","doi-asserted-by":"publisher","first-page":"30984","DOI":"10.1074\/jbc.M112.341040","volume":"287","author":"A Janzer","year":"2012","unstructured":"Janzer, A., K. Stamm, A. Becker, A. Zimmer, R. Buettner, and J. Kirfel. 2012. The H3K4me3 histone demethylase Fbxl10 is a regulator of chemokine expression, cellular morphology, and the metabolome of fibroblasts. The Journal of Biological Chemistry 287: 30984\u201330992.","journal-title":"The Journal of Biological Chemistry"},{"key":"1000_CR24","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1038\/nature06255","volume":"450","author":"D Frescas","year":"2007","unstructured":"Frescas, D., D. Guardavaccaro, F. Bassermann, R. Koyama-Nasu, and M. Pagano. 2007. JHDM1B\/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes. Nature 450: 309\u2013313.","journal-title":"Nature"},{"key":"1000_CR25","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1016\/j.molcel.2013.01.016","volume":"49","author":"X Wu","year":"2013","unstructured":"Wu, X., J.V. Johansen, and K. Helin. 2013. Fbxl10\/Kdm2b recruits polycomb repressive complex 1 to CpG islands and regulates H2A ubiquitylation. Molecular Cell 49: 1134\u20131146.","journal-title":"Molecular Cell"},{"key":"1000_CR26","doi-asserted-by":"publisher","first-page":"1445","DOI":"10.1016\/j.cell.2014.05.004","volume":"157","author":"NP Blackledge","year":"2014","unstructured":"Blackledge, N.P., A.M. Farcas, T. Kondo, H.W. King, J.F. McGouran, L.L. Hanssen, S. Ito, S. Cooper, K. Kondo, Y. Koseki, T. Ishikura, H.K. Long, T.W. Sheahan, N. Brockdorff, B.M. Kessler, H. Koseki, and R.J. Klose. 2014. Variant PRC1 complex-dependent H2A ubiquitylation drives PRC2 recruitment and polycomb domain formation. Cell 157: 1445\u20131459.","journal-title":"Cell"},{"key":"1000_CR27","first-page":"727","volume":"123","author":"A Tzatsos","year":"2013","unstructured":"Tzatsos, A., P. Paskaleva, F. Ferrari, V. Deshpande, S. Stoykova, G. Contino, K.K. Wong, F. Lan, P. Trojer, P.J. Park, and N. Bardeesy. 2013. KDM2B promotes pancreatic cancer via polycomb-dependent and -independent transcriptional programs. The Journal of Clinical Investigation 123: 727\u2013739.","journal-title":"The Journal of Clinical Investigation"},{"key":"1000_CR28","doi-asserted-by":"publisher","first-page":"3935","DOI":"10.1158\/0008-5472.CAN-13-2733","volume":"74","author":"F Kottakis","year":"2014","unstructured":"Kottakis, F., P. Foltopoulou, I. Sanidas, P. Keller, A. Wronski, B.T. Dake, S.A. Ezell, Z. Shen, S.P. Naber, P.W. Hinds, E. McNiel, C. Kuperwasser, and P.N. Tsichlis. 2014. NDY1\/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells. Cancer Research 74: 3935\u20133946.","journal-title":"Cancer Research"},{"key":"1000_CR29","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1172\/JCI84014","volume":"126","author":"J Andricovich","year":"2016","unstructured":"Andricovich, J., Y. Kai, W. Peng, A. Foudi, and A. Tzatsos. 2016. Histone demethylase KDM2B regulates lineage commitment in normal and malignant hematopoiesis. The Journal of Clinical Investigation 126: 905\u2013920.","journal-title":"The Journal of Clinical Investigation"},{"key":"1000_CR30","doi-asserted-by":"publisher","first-page":"3869","DOI":"10.1182\/blood-2010-10-312736","volume":"117","author":"J He","year":"2011","unstructured":"He, J., A.T. Nguyen, and Y. Zhang. 2011. KDM2b\/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia. Blood 117: 3869\u20133880.","journal-title":"Blood"},{"key":"1000_CR31","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1128\/CMR.00014-10","volume":"24","author":"M Vareille","year":"2011","unstructured":"Vareille, M., E. Kieninger, M.R. Edwards, and N. Regamey. 2011. The airway epithelium: soldier in the fight against respiratory viruses. Clinical Microbiology Reviews 24: 210\u2013229.","journal-title":"Clinical Microbiology Reviews"},{"issue":"10","key":"1000_CR32","doi-asserted-by":"publisher","first-page":"4980","DOI":"10.4049\/jimmunol.1400313","volume":"193","author":"HM Hsiao","year":"2014","unstructured":"Hsiao, H.M., T.H. Thatcher, E.P. Levy, R.A. Fulton, K.M. Owens, R.P. Phipps, and P.J. Sime. 2014. Resolvin D1 attenuates polyinosinic-polycytidylic acid-induced inflammatory signaling in human airway epithelial cells via TAK1. Journal of Immunology 193 (10): 4980\u20134987. https:\/\/doi.org\/10.4049\/jimmunol.1400313 .","journal-title":"Journal of Immunology"},{"key":"1000_CR33","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1016\/S0092-8674(02)00654-2","volume":"108","author":"GJ Narlikar","year":"2002","unstructured":"Narlikar, G.J., H.Y. Fan, and R.E. Kingston. 2002. Cooperation between complexes that regulate chromatin structure and transcription. Cell 108: 475\u2013487.","journal-title":"Cell"},{"key":"1000_CR34","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1146\/annurev.biochem.77.062706.153223","volume":"78","author":"CR Clapier","year":"2009","unstructured":"Clapier, C.R., and B.R. Cairns. 2009. The biology of chromatin remodeling complexes. Annual Review of Biochemistry 78: 273\u2013304.","journal-title":"Annual Review of Biochemistry"},{"key":"1000_CR35","doi-asserted-by":"publisher","first-page":"2813","DOI":"10.1084\/jem.20080938","volume":"205","author":"A Jani","year":"2008","unstructured":"Jani, A., M. Wan, J. Zhang, K. Cui, J. Wu, P. Preston-Hurlburt, R. Khatri, K. Zhao, and T. Chi. 2008. A novel genetic strategy reveals unexpected roles of the Swi-Snf-like chromatin-remodeling BAF complex in thymocyte development. The Journal of Experimental Medicine 205: 2813\u20132825.","journal-title":"The Journal of Experimental Medicine"},{"key":"1000_CR36","doi-asserted-by":"publisher","first-page":"11258","DOI":"10.1073\/pnas.0809485106","volume":"106","author":"H Gao","year":"2009","unstructured":"Gao, H., K. Lukin, J. Ramirez, S. Fields, D. Lopez, and J. Hagman. 2009. Opposing effects of SWI\/SNF and Mi-2\/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5. Proceedings of the National Academy of Sciences of the United States of America 106: 11258\u201311263.","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"1000_CR37","doi-asserted-by":"publisher","first-page":"e00205","DOI":"10.7554\/eLife.00205","volume":"1","author":"AM Farcas","year":"2012","unstructured":"Farcas, A.M., N.P. Blackledge, I. Sudbery, H.K. Long, J.F. McGouran, N.R. Rose, S. Lee, D. Sims, A. Cerase, T.W. Sheahan, H. Koseki, N. Brockdorff, C.P. Ponting, B.M. Kessler, and R.J. Klose. 2012. KDM2B links the polycomb repressive complex 1 (PRC1) to recognition of CpG islands. eLife 1: e00205.","journal-title":"eLife"},{"key":"1000_CR38","doi-asserted-by":"publisher","first-page":"820","DOI":"10.1074\/mcp.M600275-MCP200","volume":"6","author":"C S\u00e1nchez","year":"2007","unstructured":"S\u00e1nchez, C., I. S\u00e1nchez, J.A. Demmers, P. Rodriguez, J. Strouboulis, and M. Vidal. 2007. Proteomics analysis of Ring1B\/Rnf2 interactors identifies a novel complex with the Fbxl10\/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Molecular & Cellular Proteomics 6: 820\u2013834.","journal-title":"Molecular & Cellular Proteomics"},{"key":"1000_CR39","doi-asserted-by":"publisher","first-page":"6880","DOI":"10.1128\/MCB.00630-06","volume":"26","author":"MD Gearhart","year":"2006","unstructured":"Gearhart, M.D., C.M. Corcoran, J.A. Wamstad, and V.J. Bardwell. 2006. Polycomb group and SCF ubiquitin ligases are found in a novel BCOR complex that is recruited to BCL6 targets. Molecular and Cellular Biology 26: 6880\u20136889.","journal-title":"Molecular and Cellular Biology"},{"issue":"2","key":"1000_CR40","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1038\/s41419-017-0090-8","volume":"19","author":"Z Chen","year":"2018","unstructured":"Chen, Z., X. Lu, D. Jia, Y. Jing, D. Chen, Q. Wang, F. Zhao, J. Li, M. Yao, W. Cong, and X. He. 2018. Hepatic SMARCA4 predicts HCC recurrence and promotes tumour cell proliferation by regulating SMAD6 expression. Cell Death & Disease 19 (2): 59.","journal-title":"Cell Death & Disease"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-019-01000-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10753-019-01000-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-019-01000-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T05:03:58Z","timestamp":1663391038000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10753-019-01000-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,30]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["1000"],"URL":"https:\/\/doi.org\/10.1007\/s10753-019-01000-6","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,30]]},"assertion":[{"value":"30 April 2019","order":1,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"All authors declared that no conflict of interest exists.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}