{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T20:41:33Z","timestamp":1789245693389,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T00:00:00Z","timestamp":1602806400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T00:00:00Z","timestamp":1602806400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871293"],"award-info":[{"award-number":["81871293"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800070"],"award-info":[{"award-number":["81800070"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81572442"],"award-info":[{"award-number":["81572442"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s10753-020-01350-6","type":"journal-article","created":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T17:02:35Z","timestamp":1602867755000},"page":"536-548","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["CGRP-Mediated Prolactin Upregulation: a Possible Pathomechanism in IgG4-Related Disease"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1766-9395","authenticated-orcid":false,"given":"Qicai","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunfeng","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingquan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbin","family":"Rui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoting","family":"Lv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,10,16]]},"reference":[{"key":"1350_CR1","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1038\/nrrheum.2013.183","volume":"10","author":"M Yamamoto","year":"2014","unstructured":"Yamamoto, M., H. Takahashi, and Y. Shinomura. 2014. Mechanisms and assessment of IgG4-related disease: Lessons for the rheumatologist. Nat Rev Rheumatol 10: 148\u2013159.","journal-title":"Nat Rev Rheumatol"},{"key":"1350_CR2","doi-asserted-by":"publisher","first-page":"534","DOI":"10.1136\/gut.2006.105528","volume":"56","author":"GO Ceyhan","year":"2007","unstructured":"Ceyhan, G.O., F. Bergmann, M. Kadihasanoglu, M. Erkan, W. Park, U. Hinz, T. Giese, M.W. Muller, M.W. Buchler, N.A. Giese, and H. Friess. 2007. The neurotrophic factor artemin influences the extent of neural damage and growth in chronic pancreatitis. Gut 56: 534\u2013544.","journal-title":"Gut"},{"key":"1350_CR3","doi-asserted-by":"publisher","first-page":"e2591","DOI":"10.1038\/cddis.2017.32","volume":"8","author":"QC Liu","year":"2017","unstructured":"Liu, Q.C., F. Chen, C.Y. Wu, F. Gao, Z.H. Zhuang, J.T. Chen, B. Cai, T. Zhang, L. Guo, L.Q. Lin, C.F. Zhao, and X.H. Lin. 2017. CALCB splice region pathogenic variants leading to plasma cell neurotropic enrichment in type 1 autoimmune pancreatitis. Cell Death Dis 8: e2591.","journal-title":"Cell Death Dis"},{"key":"1350_CR4","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1159\/000212099","volume":"9","author":"L Schneider","year":"2009","unstructured":"Schneider, L., W. Hartwig, T. Flemming, T. Hackert, F. Fortunato, M. Heck, M.M. Gebhard, P.P. Nawroth, A. Bierhaus, M.W. B\u00fcchler, and J. Werner. 2009. Protective effects and anti-inflammatory pathways of exogenous calcitonin gene-related peptide in severe necrotizing pancreatitis. Pancreatology 9: 662\u2013669.","journal-title":"Pancreatology"},{"key":"1350_CR5","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1038\/nm.2932","volume":"18","author":"M Minamiyama","year":"2012","unstructured":"Minamiyama, M., M. Katsuno, H. Adachi, H. Doi, N. Kondo, M. Iida, S. Ishigaki, Y. Fujioka, S. Matsumoto, Y. Miyazaki, F. Tanaka, H. Kurihara, and G. Sobue. 2012. Naratriptan mitigates CGRP1-associated motor neuron degeneration caused by an expanded polyglutamine repeat tract. Nat Med 18: 1531\u20131538.","journal-title":"Nat Med"},{"key":"1350_CR6","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1111\/ajt.14515","volume":"18","author":"SS Chavan","year":"2018","unstructured":"Chavan, S.S., P. Ma, and I.M. Chiu. 2018. Neuro-immune interactions in inflammation and host defense: Implications for transplantation. Am J Transplant 18: 556\u2013563.","journal-title":"Am J Transplant"},{"key":"1350_CR7","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1159\/000125411","volume":"51","author":"A Fahim","year":"1990","unstructured":"Fahim, A., V. Rettori, and S.M. McCann. 1990. The role of calcitonin gene-related peptide in the control of growth hormone and prolactin release. Neuroendocrinology 51: 688\u2013693.","journal-title":"Neuroendocrinology"},{"key":"1350_CR8","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s10620-007-9848-7","volume":"53","author":"BJ Thompson","year":"2008","unstructured":"Thompson, B.J., M.K. Washington, U. Kurre, M. Singh, E.Y. Rula, and R.B. Emeson. 2008. Protective roles of alpha-calcitonin and beta-calcitonin gene-related peptide in spontaneous and experimentally induced colitis. Dig Dis Sci 53: 229\u2013241.","journal-title":"Dig Dis Sci"},{"key":"1350_CR9","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1089\/jir.2019.0184","volume":"40","author":"X Lv","year":"2020","unstructured":"Lv, X., F. Gao, S. Zhang, S. Zhang, X. Zhou, F. Ding, J. Wang, Q. Chen, M. Chen, and Q. Liu. 2020. Maladjustment of \u03b2-CGRP\/\u03b1-CGRP regulation of AQP5 promotes transition of alveolar epithelial cell apoptosis to pulmonary fibrosis. J Interferon Cytokine Res. 40: 377\u2013388.","journal-title":"J Interferon Cytokine Res."},{"key":"1350_CR10","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.molimm.2017.08.020","volume":"91","author":"JX Duan","year":"2017","unstructured":"Duan, J.X., Y. Zhou, A.Y. Zhou, X.X. Guan, T. Liu, H.H. Yang, H. Xie, and P. Chen. 2017. Calcitonin gene-related peptide exerts anti-inflammatory property through regulating murine macrophages polarization in vitro. Mol Immunol 91: 105\u2013113.","journal-title":"Mol Immunol"},{"key":"1350_CR11","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1111\/j.1471-4159.2006.04319.x","volume":"100","author":"RH Quarles","year":"2007","unstructured":"Quarles, R.H. 2007. Myelin-associated glycoprotein (MAG): Past, present and beyond. J Neurochem 100: 1431\u20131448.","journal-title":"J Neurochem"},{"key":"1350_CR12","doi-asserted-by":"publisher","first-page":"E3689","DOI":"10.1073\/pnas.1619386114","volume":"114","author":"R Herrendorff","year":"2017","unstructured":"Herrendorff, R., P. H\u00e4nggi, H. Pfister, F. Yang, D. Demeestere, F. Hunziker, S. Frey, N. Schaeren-Wiemers, A.J. Steck, and B. Ernst. 2017. Selective in vivo removal of pathogenic anti-MAG autoantibodies, an antigen-specific treatment option for anti-MAG neuropathy. Proc Natl Acad Sci USA 114: E3689\u2013E3698.","journal-title":"Proc Natl Acad Sci USA"},{"key":"1350_CR13","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.pneurobio.2010.09.004","volume":"93","author":"N Takahashi","year":"2011","unstructured":"Takahashi, N., T. Sakurai, K.L. Davis, and J.D. Buxbaum. 2011. Linking oligodendrocyte and myelin dysfunction to neurocircuitry abnormalities in schizophrenia. Prog Neurobiol 93: 13\u201324.","journal-title":"Prog Neurobiol"},{"key":"1350_CR14","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1016\/S1474-4422(17)30126-6","volume":"16","author":"MA Giamberardino","year":"2017","unstructured":"Giamberardino, M.A., and R. Costantini. 2017. Challenging chronic migraine: Targeting the CGRP receptor. Lancet Neurol 16: 410\u2013411.","journal-title":"Lancet Neurol"},{"key":"1350_CR15","doi-asserted-by":"publisher","first-page":"5475","DOI":"10.1167\/iovs.12-9935","volume":"53","author":"R Matsuda","year":"2012","unstructured":"Matsuda, R., T. Kezuka, C. Nishiyama, Y. Usui, Y. Matsunaga, Y. Okunuki, N. Yamakawa, H. Ogawa, K. Okumura, and H. Goto. 2012. Suppression of murine experimental autoimmune optic neuritis by mature dendritic cells transfected with calcitonin gene-related peptide gene. Invest Ophthalmol Vis Sci 53: 5475\u20135485.","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1350_CR16","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1038\/s41593-018-0324-9","volume":"22","author":"T Zhou","year":"2019","unstructured":"Zhou, T., Y. Zheng, L. Sun, S.R. Badea, Y. Jin, Y. Liu, A.J. Rolfe, H. Sun, X. Wang, Z. Cheng, Z. Huang, N. Zhao, X. Sun, J. Li, J. Fan, C. Lee, T.L. Megraw, W. Wu, G. Wang, and Y. Ren. 2019. Microvascular endothelial cells engulf myelin debris and promote macrophage recruitment and fibrosis after neural injury. Nat Neurosci 22: 421\u2013435.","journal-title":"Nat Neurosci"},{"key":"1350_CR17","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1038\/s41582-018-0003-1","volume":"14","author":"L Edvinsson","year":"2018","unstructured":"Edvinsson, L., K.A. Haanes, K. Warfvinge, and D.N. Krause. 2018. CGRP as the target of new migraine therapies-successful translation from bench to clinic. Nat Rev Neurol 14: 338\u2013350.","journal-title":"Nat Rev Neurol"},{"key":"1350_CR18","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.nbd.2009.05.011","volume":"35","author":"C Ringer","year":"2009","unstructured":"Ringer, C., E. Weihe, and B. Schutz. 2009. Pre-symptomatic alterations in subcellular betaCGRP distribution in motor neurons precede astrogliosis in ALS mice. Neurobiol Dis 35: 286\u2013295.","journal-title":"Neurobiol Dis"},{"key":"1350_CR19","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1038\/s41467-017-01525-0","volume":"8","author":"E Benedetti","year":"2017","unstructured":"Benedetti, E., M. Pu\u010di\u0107-Bakovi\u0107, T. Keser, A. Wahl, A. Hassinen, J.Y. Yang, L. Liu, I. Trbojevi\u0107-Akma\u010di\u0107, G. Razdorov, J. \u0160tambuk, L. Klari\u0107, I. Ugrina, M.H.J. Selman, M. Wuhrer, I. Rudan, O. Polasek, C. Hayward, H. Grallert, K. Strauch, A. Peters, T. Meitinger, C. Gieger, M. Vilaj, G.J. Boons, K.W. Moremen, T. Ovchinnikova, N. Bovin, S. Kellokumpu, F.J. Theis, G. Lauc, and J. Krumsiek. 2017. Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway. Nat Commun 8: 1483.","journal-title":"Nat Commun"},{"key":"1350_CR20","first-page":"BR418","volume":"9","author":"A Dembi\u0144ski","year":"2003","unstructured":"Dembi\u0144ski, A., Z. Warzecha, P. Ceranowicz, J. Jaworek, R. Sendur, A. Knafel, M. Dembi\u0144ski, J. Bilski, W.W. Pawlik, R. Tomaszewska, J. Stachura, and S.J. Konturek. 2003. Stimulation of sensory nerves and CGRP attenuate pancreatic damage in ischemia\/reperfusion induced pancreatitis. Med Sci Monit 9: BR418\u2013BR425.","journal-title":"Med Sci Monit"},{"key":"1350_CR21","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.1038\/s41467-017-01841-5","volume":"8","author":"R Simeoli","year":"2017","unstructured":"Simeoli, R., K. Montague, H.R. Jones, L. Castaldi, D. Chambers, J.H. Kelleher, V. Vacca, T. Pitcher, J. Grist, H. al-Ahdal, L.F. Wong, M. Perretti, J. Lai, P. Mouritzen, P. Heppenstall, and M. Malcangio. 2017. Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma. Nat Commun 8: 1778.","journal-title":"Nat Commun"},{"key":"1350_CR22","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.autrev.2014.11.005","volume":"14","author":"M Costanza","year":"2015","unstructured":"Costanza, M., N. Binart, L. Steinman, and R. Pedotti. 2015. Prolactin: A versatile regulator of inflammation and autoimmune pathology. Autoimmun Rev 14: 223\u2013230.","journal-title":"Autoimmun Rev"},{"key":"1350_CR23","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.4049\/jimmunol.1301128","volume":"191","author":"M Costanza","year":"2013","unstructured":"Costanza, M., S. Musio, M. Abou-Hamdan, N. Binart, and R. Pedotti. 2013. Prolactin is not required for the development of severe chronic experimental autoimmune encephalomyelitis. J Immunol 191: 2082\u20132088.","journal-title":"J Immunol"},{"key":"1350_CR24","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1089\/jir.2018.0020","volume":"38","author":"LH Peng","year":"2018","unstructured":"Peng, L.H., X.Q. Qin, R.R. Tan, C. Liu, H.J. Liu, and X. Qu. 2018. Calcitonin gene-related peptide regulates the potential antigen uptake ability of human bronchial epithelial cells. J Interferon Cytokine Res. 38: 463\u2013468.","journal-title":"J Interferon Cytokine Res."},{"key":"1350_CR25","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1038\/nm.4501","volume":"24","author":"P Baral","year":"2018","unstructured":"Baral, P., B.D. Umans, L. Li, A. Wallrapp, M. Bist, T. Kirschbaum, Y. Wei, Y. Zhou, V.K. Kuchroo, P.R. Burkett, B.G. Yipp, S.D. Liberles, and I.M. Chiu. 2018. Nociceptor sensory neurons suppress neutrophil and \u03b3\u03b4 T cell responses in bacterial lung infections and lethal pneumonia. Nat Med 24: 417\u2013416.","journal-title":"Nat Med"},{"key":"1350_CR26","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1038\/nrendo.2015.36","volume":"11","author":"V Bernard","year":"2015","unstructured":"Bernard, V., J. Young, P. Chanson, and N. Binart. 2015. New insights in prolactin: pathological implications. Nat Rev Endocrinol 11: 265\u2013275.","journal-title":"Nat Rev Endocrinol"},{"key":"1350_CR27","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1038\/nrendo.2015.168","volume":"12","author":"W Savino","year":"2016","unstructured":"Savino, W., D.A. Mendes-da-Cruz, A. Lepletier, and M. Dardenne. 2016. Hormonal control of T-cell development in health and disease. Nat Rev Endocrinol 12: 77\u201389.","journal-title":"Nat Rev Endocrinol"},{"key":"1350_CR28","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1038\/s41593-018-0324-9","volume":"22","author":"T Zhou","year":"2019","unstructured":"Zhou, T., Y. Zheng, L. Sun, S.R. Badea, Y. Jin, Y. Liu, A.J. Rolfe, H. Sun, X. Wang, Z. Cheng, Z. Huang, N. Zhao, X. Sun, J. Li, J. Fan, C. Lee, T.L. Megraw, W. Wu, G. Wang, and Y. Ren. 2019. Microvascular endothelial cells engulf myelin debris and promote macrophage recruitment and fibrosis after neural injury. Nat Neurosci 22: 421\u2013435.","journal-title":"Nat Neurosci"},{"key":"1350_CR29","doi-asserted-by":"publisher","first-page":"42413","DOI":"10.1038\/srep42413","volume":"7","author":"S Furukawa","year":"2017","unstructured":"Furukawa, S., M. Moriyama, K. Miyake, H. Nakashima, A. Tanaka, T. Maehara, M. Iizuka-Koga, H. Tsuboi, J.N. Hayashida, N. Ishiguro, M. Yamauchi, T. Sumida, and S. Nakamura. 2017. Interleukin-33 produced by M2 macrophages and other immune cells contributes to Th2 immune reaction of IgG4-related disease. Sci Rep. 7: 42413.","journal-title":"Sci Rep."},{"key":"1350_CR30","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.clim.2014.10.008","volume":"156","author":"S Furukawa","year":"2015","unstructured":"Furukawa, S., M. Moriyama, A. Tanaka, T. Maehara, H. Tsuboi, M. Iizuka, J.N. Hayashida, M. Ohta, T. Saeki, K. Notohara, T. Sumida, and S. Nakamura. 2015. Preferential M2 macrophages contribute to fibrosis in IgG4-related dacryoadenitis and sialoadenitis, so-called Mikulicz\u2019s disease. Clin Immunol. 156: 9\u201318.","journal-title":"Clin Immunol."},{"key":"1350_CR31","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.4161\/19420862.2014.975657","volume":"6","author":"JF Swisher","year":"2014","unstructured":"Swisher, J.F., D.A. Haddad, A.G. McGrath, et al. 2014. IgG4 can induce an M2-like phenotype in human monocyte-derived macrophages through Fc\u03b3RI. MAbs. 6: 1377\u20131384.","journal-title":"MAbs."},{"key":"1350_CR32","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1080\/14397595.2018.1436029","volume":"28","author":"M Yamamoto","year":"2018","unstructured":"Yamamoto, M., K. Takano, R. Kamekura, C. Suzuki, S. Ichimiya, T. Himi, H. Nakase, and H. Takahashi. 2018. Stage classification of IgG4-related dacryoadenitis and sialadenitis by the serum cytokine environment. Mod Rheumatol. 28: 1004\u20131008.","journal-title":"Mod Rheumatol."},{"key":"1350_CR33","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1016\/j.jaci.2015.12.1330","volume":"138","author":"JM Drijvers","year":"2016","unstructured":"Drijvers, J.M., J. Daccache, M.N. Carruthers, et al. 2016. Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease. J Allergy Clin Immunol. 138: 825\u2013838.","journal-title":"J Allergy Clin Immunol."},{"key":"1350_CR34","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1016\/j.humpath.2013.07.047","volume":"45","author":"S Yokoi","year":"2014","unstructured":"Yokoi, S., Y. Kawagashira, K. Ohyama, M. Iijima, H. Koike, H. Watanabe, A. Tatematsu, S. Nakamura, and G. Sobue. 2014. Mononeuritis multiplex with tumefactive cellular infiltration in a patient with reactive lymphoid hyperplasia with increased immunoglobulin G4-positive cells. Hum Pathol. 45: 427\u2013430.","journal-title":"Hum Pathol."},{"key":"1350_CR35","doi-asserted-by":"publisher","first-page":"324","DOI":"10.1016\/j.chom.2018.01.018","volume":"23","author":"A Gluschko","year":"2018","unstructured":"Gluschko, A., M. Herb, K. Wiegmann, O. Krut, W.F. Neiss, O. Uterm\u00f6hlen, M. Kr\u00f6nke, and M. Schramm. 2018. The \u03b22 Integrin Mac-1 induces protective LC3-associated phagocytosis of Listeria monocytogenes. Cell Host Microbe. 23: 324\u2013337.","journal-title":"Cell Host Microbe."},{"key":"1350_CR36","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1080\/15548627.2018.1475816","volume":"14","author":"M Herb","year":"2018","unstructured":"Herb, M., A. Gluschko, and M. Schramm. 2018. LC3-associated phagocytosis initiated by integrin ITGAM-ITGB2\/Mac-1 enhances immunity to Listeria monocytogenes. Autophagy. 14: 1462\u20131464.","journal-title":"Autophagy."},{"key":"1350_CR37","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1038\/nm0198-078","volume":"4","author":"J Liu","year":"1998","unstructured":"Liu, J., M.W. Marino, G. Wong, D. Grail, A. Dunn, J. Bettadapura, A.J. Slavin, L. Old, and C.C.A. Bernard. 1998. TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination. Nat Med. 4: 78\u201383.","journal-title":"Nat Med."}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-020-01350-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10753-020-01350-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-020-01350-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T18:46:56Z","timestamp":1698259616000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10753-020-01350-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,16]]},"references-count":37,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["1350"],"URL":"https:\/\/doi.org\/10.1007\/s10753-020-01350-6","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,16]]},"assertion":[{"value":"21 August 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 September 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"The data collection scheme and research carried out were approved by the Medical ethics committee of the First Affiliated Hospital of Fujian Medical University. The protocol was approved by the Medical ethics committee of the First Affiliated Hospital of Fujian Medical University.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}}]}}