{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T17:30:54Z","timestamp":1787679054416,"version":"build-2784847793"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T00:00:00Z","timestamp":1629763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T00:00:00Z","timestamp":1629763200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"National Key Research and Development Project","award":["2018YFC1705304"],"award-info":[{"award-number":["2018YFC1705304"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s10753-021-01544-6","type":"journal-article","created":{"date-parts":[[2021,8,24]],"date-time":"2021-08-24T06:03:38Z","timestamp":1629785018000},"page":"267-278","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Involvement of miR-214-3p\/FOXM1 Axis During the Progression of Psoriasis"],"prefix":"10.1007","volume":"45","author":[{"given":"Jin","family":"Zhao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingjun","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liuqing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6107-5784","authenticated-orcid":false,"given":"Rongyi","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,8,24]]},"reference":[{"issue":"9997","key":"1544_CR1","doi-asserted-by":"publisher","first-page":"983","DOI":"10.1016\/S0140-6736(14)61909-7","volume":"386","author":"W-H Boehncke","year":"2015","unstructured":"Boehncke, W.-H., and M.P. Sch\u00f6n. 2015. Psoriasis. The Lancet 386 (9997): 983\u2013994.","journal-title":"The Lancet"},{"key":"1544_CR2","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1146\/annurev-immunol-032713-120225","volume":"32","author":"MA Lowes","year":"2014","unstructured":"Lowes, M.A., M. Suarez-Farinas, and J.G. Krueger. 2014. Immunology of psoriasis. Annual Review of Immunology 32: 227\u2013255.","journal-title":"Annual Review of Immunology"},{"issue":"4","key":"1544_CR3","doi-asserted-by":"publisher","first-page":"596","DOI":"10.1016\/j.immuni.2011.08.001","volume":"35","author":"Y Cai","year":"2011","unstructured":"Cai, Y., et al. 2011. Pivotal role of dermal IL-17-producing gammadelta T cells in skin inflammation. Immunity 35 (4): 596\u2013610.","journal-title":"Immunity"},{"key":"1544_CR4","doi-asserted-by":"crossref","unstructured":"Tan Gana, N.H.,\u00a0A.F. Victoriano, and\u00a0T.\u00a0Okamoto.\u00a02012.\u00a0Evaluation of online miRNA resources for biomedical applications. Genes Cells\u00a017 (1): 11\u201327.","DOI":"10.1111\/j.1365-2443.2011.01564.x"},{"issue":"4","key":"1544_CR5","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1177\/0300985813502820","volume":"51","author":"M Bhaskaran","year":"2014","unstructured":"Bhaskaran, M., and M. Mohan. 2014. MicroRNAs: History, biogenesis, and their evolving role in animal development and disease. Veterinary Pathology 51 (4): 759\u2013774.","journal-title":"Veterinary Pathology"},{"issue":"1","key":"1544_CR6","doi-asserted-by":"publisher","first-page":"111","DOI":"10.3892\/ol.2017.6102","volume":"14","author":"T Zhang","year":"2017","unstructured":"Zhang, T., et al. 2017. MicroRNA-4530 promotes angiogenesis by targeting VASH1 in breast carcinoma cells. Oncology Letters 14 (1): 111\u2013118.","journal-title":"Oncology Letters"},{"issue":"5","key":"1544_CR7","doi-asserted-by":"publisher","first-page":"685","DOI":"10.7150\/ijbs.7.685","volume":"7","author":"X Yang","year":"2011","unstructured":"Yang, X., et al. 2011. miR-21 promotes keratinocyte migration and re-epithelialization during wound healing. International Journal of Biological Sciences 7 (5): 685\u2013690.","journal-title":"International Journal of Biological Sciences"},{"issue":"7","key":"1544_CR8","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.1038\/jid.2011.55","volume":"131","author":"N Xu","year":"2011","unstructured":"Xu, N., et al. 2011. MiR-125b, a MicroRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. Journal of Investigative Dermatology 131 (7): 1521\u20131529.","journal-title":"Journal of Investigative Dermatology"},{"issue":"6","key":"1544_CR9","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1172\/JCI97426","volume":"128","author":"R Wu","year":"2018","unstructured":"Wu, R., et al. 2018. MicroRNA-210 overexpression promotes psoriasis-like inflammation by inducing Th1 and Th17 cell differentiation. Journal of Clinical Investigation 128 (6): 2551\u20132568.","journal-title":"Journal of Clinical Investigation"},{"issue":"6","key":"1544_CR10","doi-asserted-by":"publisher","first-page":"1676","DOI":"10.1038\/jid.2015.48","volume":"135","author":"D Li","year":"2015","unstructured":"Li, D., et al. 2015. MicroRNA-31 promotes skin wound healing by enhancing keratinocyte proliferation and migration. Journal of Investigative Dermatology 135 (6): 1676\u20131685.","journal-title":"Journal of Investigative Dermatology"},{"key":"1544_CR11","doi-asserted-by":"publisher","first-page":"7652","DOI":"10.1038\/ncomms8652","volume":"6","author":"S Yan","year":"2015","unstructured":"Yan, S., et al. 2015. NF-kappaB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nature Communications 6: 7652.","journal-title":"Nature Communications"},{"key":"1544_CR12","doi-asserted-by":"crossref","unstructured":"Lerman, G., et al.\u00a02014. The crosstalk between IL-22 signaling and miR-197 in human keratinocytes. PLoS One\u00a09 (9): p. e107467.","DOI":"10.1371\/journal.pone.0107467"},{"issue":"2","key":"1544_CR13","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/j.jdermsci.2020.03.006","volume":"98","author":"Z Yu","year":"2020","unstructured":"Yu, Z., et al. 2020. High-throughput transcriptome and pathogenesis analysis of clinical psoriasis. Journal of Dermatological Science 98 (2): 109\u2013118.","journal-title":"Journal of Dermatological Science"},{"issue":"2","key":"1544_CR14","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1111\/bjd.13721","volume":"173","author":"L Raaby","year":"2015","unstructured":"Raaby, L., et al. 2015. Changes in mRNA expression precede changes in microRNA expression in lesional psoriatic skin during treatment with adalimumab. British Journal of Dermatology 173 (2): 436\u2013447.","journal-title":"British Journal of Dermatology"},{"issue":"207","key":"1544_CR15","first-page":"42792","volume":"7","author":"Fergal C Kelleher","year":"2015","unstructured":"Kelleher, Fergal C., and H.O.S., . 2015. FOXM1 in sarcoma: Role in cell cycle, pluripotency genes and stem cell pathways. Oncotarget 7 (207): 42792\u201342804.","journal-title":"Oncotarget"},{"issue":"3","key":"1544_CR16","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/S0960-7404(03)00006-9","volume":"12","author":"MS Kahlenberg","year":"2003","unstructured":"Kahlenberg, M.S., et al. 2003. Molecular prognostics in colorectal cancer. Surgical Oncology 12 (3): 173\u2013186.","journal-title":"Surgical Oncology"},{"issue":"11","key":"1544_CR17","first-page":"1193","volume":"9","author":"WS Samowitz","year":"2000","unstructured":"Samowitz, W.S., et al. 2000. Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: A population-based study. Cancer Epidemiology Biomarkers and Prevention 9 (11): 1193\u20131197.","journal-title":"Cancer Epidemiology Biomarkers and Prevention"},{"issue":"1","key":"1544_CR18","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/0960-7404(92)90062-P","volume":"1","author":"AM Kluftinger","year":"1992","unstructured":"Kluftinger, A.M., et al. 1992. Correlation of epidermal growth factor receptor and c-erbB2 oncogene product to known prognostic indicators of colorectal cancer. Surgical Oncology 1 (1): 97\u2013105.","journal-title":"Surgical Oncology"},{"issue":"3","key":"1544_CR19","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1097\/00130404-200605000-00012","volume":"12","author":"P Kountourakis","year":"2006","unstructured":"Kountourakis, P., et al. 2006. Clinicopathologic significance of EGFR and Her-2\/neu in colorectal adenocarcinomas. Cancer Journal 12 (3): 229\u2013236.","journal-title":"Cancer Journal"},{"key":"1544_CR20","doi-asserted-by":"crossref","unstructured":"Pereira, C.B.L., et al.\u00a02013. Prognostic and predictive significance of MYC and KRAS alterations in breast cancer from women treated with neoadjuvant chemotherapy. PLoS ONE\u00a08 (3).","DOI":"10.1371\/journal.pone.0060576"},{"key":"1544_CR21","doi-asserted-by":"crossref","unstructured":"Banin Hirata, B.K., et al.\u00a02014. Molecular markers for breast cancer: prediction on tumor behavior. Disease Markers 2014.","DOI":"10.1155\/2014\/513158"},{"key":"1544_CR22","doi-asserted-by":"crossref","unstructured":"Yang, P., et al.\u00a02013. The impact of p53 in predicting clinical outcome of breast cancer patients with visceral metastasis. Scientific Reports\u00a03.","DOI":"10.1038\/srep02246"},{"key":"1544_CR23","first-page":"1","volume":"5","author":"N Jaiswal","year":"2014","unstructured":"Jaiswal, N., S. Chakraborty, and A. Nag. 2014. Biology of FOXM1 and its emerging role in cancer therapy. J Proteins Proteomics 5: 1\u201324.","journal-title":"J Proteins Proteomics"},{"key":"1544_CR24","doi-asserted-by":"crossref","unstructured":"Tian, S., et al.\u00a02012. Meta-analysis derived (MAD) transcriptome of psoriasis defines the \"core\" pathogenesis of disease. PLoS One\u00a07 (9): p. e44274.","DOI":"10.1371\/journal.pone.0044274"},{"issue":"4","key":"1544_CR25","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1016\/j.immuni.2018.03.019","volume":"48","author":"M Xu","year":"2018","unstructured":"Xu, M., et al. 2018. An interleukin-25-mediated autoregulatory circuit in keratinocytes plays a pivotal role in psoriatic skin inflammation. Immunity 48 (4): 787-798.e4.","journal-title":"Immunity"},{"issue":"318","key":"1544_CR26","first-page":"13","volume":"10","author":"QH Lili Jiang","year":"2010","unstructured":"Lili Jiang, Q.H. 2010. Siyang Zhang, Hsa-miR-125a-3p and hsa-miR-125a-5p are downregulated in non-small cell lung cancer and have inverse effects on invasion and migration of lung cancer cells. BMC Cancer 10 (318): 13.","journal-title":"BMC Cancer"},{"key":"1544_CR27","doi-asserted-by":"crossref","unstructured":"Yin, F., et al.\u00a02015. MiR-125a-3p regulates glioma apoptosis and invasion by regulating Nrg1. PLoS One\u00a010(1): p. e0116759.","DOI":"10.1371\/journal.pone.0116759"},{"issue":"3","key":"1544_CR28","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1002\/gcc.20837","volume":"50","author":"M Hisaoka","year":"2011","unstructured":"Hisaoka, M., et al. 2011. Identification of altered MicroRNA expression patterns in synovial sarcoma. Genes Chromosomes and Cancer 50 (3): 137\u2013145.","journal-title":"Genes Chromosomes and Cancer"},{"issue":"5","key":"1544_CR29","first-page":"1385","volume":"38","author":"X Xu","year":"2011","unstructured":"Xu, X., et al. 2011. Microarray-based analysis: Identification of hypoxia-regulated microRNAs in retinoblastoma cells. International Journal of Oncology 38 (5): 1385\u20131393.","journal-title":"International Journal of Oncology"},{"key":"1544_CR30","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s40169-015-0054-5","volume":"4","author":"WR Swindell","year":"2015","unstructured":"Swindell, W.R., et al. 2015. Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites. Clinical and Translational Medicine 4: 13.","journal-title":"Clinical and Translational Medicine"},{"issue":"3","key":"1544_CR31","doi-asserted-by":"publisher","first-page":"245","DOI":"10.1158\/1535-7163.MCT-12-0712","volume":"12","author":"M Halasi","year":"2013","unstructured":"Halasi, M., and A.L. Gartel. 2013. FOX(M1) news\u2013it is cancer. Molecular Cancer Therapeutics 12 (3): 245\u2013254.","journal-title":"Molecular Cancer Therapeutics"},{"issue":"35","key":"1544_CR32","doi-asserted-by":"publisher","first-page":"25167","DOI":"10.1074\/jbc.M603906200","volume":"281","author":"PA Madureira","year":"2006","unstructured":"Madureira, P.A., et al. 2006. The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer cells. Journal of Biological Chemistry 281 (35): 25167\u201325176.","journal-title":"Journal of Biological Chemistry"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-021-01544-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10753-021-01544-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-021-01544-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T22:18:07Z","timestamp":1643667487000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10753-021-01544-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,24]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["1544"],"URL":"https:\/\/doi.org\/10.1007\/s10753-021-01544-6","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-196410\/v1","asserted-by":"object"}]},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,24]]},"assertion":[{"value":"21 December 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 August 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 August 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"DECLARATIONS"}},{"value":"All animal experiments were approved under the guidelines of the Animal Experimental Ethics Committee of the Hubei University of Chinese Medicine.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Concent to Participate"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Concent for Publication"}},{"value":"The authors declare no competing interests.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}