{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:25:26Z","timestamp":1793139926668,"version":"4.5.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T00:00:00Z","timestamp":1669334400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1007\/s10753-022-01757-3","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T21:31:33Z","timestamp":1669411893000},"page":"584-597","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Radial Extracorporeal Shock Wave Therapy Combined with Resveratrol Derivative Alleviates Chronic Nonbacterial Prostatitis in Rats"],"prefix":"10.1007","volume":"46","author":[{"given":"Zhengyao","family":"Song","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zichen","family":"Bian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaozhao","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,11,25]]},"reference":[{"key":"1757_CR1","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1016\/j.pop.2010.04.007","volume":"37","author":"K Ramakrishnan","year":"2010","unstructured":"Ramakrishnan, K., and R. Salinas. 2010. Prostatitis: Acute and chronic. Primary Care 37: 547\u201363. https:\/\/doi.org\/10.1016\/j.pop.2010.04.007 (viii-ix).","journal-title":"Primary Care"},{"key":"1757_CR2","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1038\/pcan.2016.8","volume":"19","author":"A Polackwich","year":"2016","unstructured":"Polackwich, A., and D. Shoskes. 2016. Chronic prostatitis\/chronic pelvic pain syndrome: A review of evaluation and therapy. Prostate Cancer and Prostatic Diseases 19: 132\u2013138. https:\/\/doi.org\/10.1038\/pcan.2016.8.","journal-title":"Prostate Cancer and Prostatic Diseases"},{"key":"1757_CR3","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1038\/nrurol.2014.63","volume":"11","author":"S Murphy","year":"2014","unstructured":"Murphy, S., A. Schaeffer, and P. Thumbikat. 2014. Immune mediators of chronic pelvic pain syndrome. Nature Reviews. Urology 11: 259\u2013269. https:\/\/doi.org\/10.1038\/nrurol.2014.63.","journal-title":"Nature Reviews. Urology"},{"key":"1757_CR4","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1080\/15622975.2018.1533994","volume":"21","author":"C Lien","year":"2020","unstructured":"Lien, C., C. Chung, C. Lin, and C. Chang. 2020. Increased risk of prostatitis in male patients with depression. The World Journal of Biological Psychiatry: The Official Journal of the World Federation of Societies of Biological Psychiatry 21: 111\u2013118. https:\/\/doi.org\/10.1080\/15622975.2018.1533994.","journal-title":"The World Journal of Biological Psychiatry: The Official Journal of the World Federation of Societies of Biological Psychiatry"},{"key":"1757_CR5","doi-asserted-by":"publisher","first-page":"116","DOI":"10.2174\/1568026619666190301173958","volume":"19","author":"R Kataria","year":"2019","unstructured":"Kataria, R., and A. Khatkar. 2019. Resveratrol in various pockets: A review. Current Topics in Medicinal Chemistry 19: 116\u2013122. https:\/\/doi.org\/10.2174\/1568026619666190301173958.","journal-title":"Current Topics in Medicinal Chemistry"},{"key":"1757_CR6","doi-asserted-by":"publisher","first-page":"3542","DOI":"10.3390\/molecules27113542","volume":"27","author":"N Zhou","year":"2022","unstructured":"Zhou, N., Y. Tian, H. Wu, Y. Cao, R. Li, and K. Zou. 2022. Protective effect of resveratrol on immortalized duck intestinal epithelial cells exposed to H(2)O(2). Molecules 27: 3542. https:\/\/doi.org\/10.3390\/molecules27113542.","journal-title":"Molecules"},{"key":"1757_CR7","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1080\/10408347.2019.1637242","volume":"50","author":"B Fiod Riccio","year":"2020","unstructured":"Fiod Riccio, B., B. Fonseca-Santos, P. Colerato Ferrari, and M. Chorilli. 2020. Transcharacteristics, biological properties and analytical methods of -resveratrol: A review. Critical Reviews in Analytical Chemistry 50: 339\u2013358. https:\/\/doi.org\/10.1080\/10408347.2019.1637242.","journal-title":"Critical Reviews in Analytical Chemistry"},{"key":"1757_CR8","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1002\/med.21565","volume":"39","author":"A Singh","year":"2019","unstructured":"Singh, A., R. Singh, S. Verma, V. Rai, C. Kaschula, P. Maiti, and S. Gupta. 2019. Health benefits of resveratrol: Evidence from clinical studies. Medicinal Research Reviews 39: 1851\u20131891. https:\/\/doi.org\/10.1002\/med.21565.","journal-title":"Medicinal Research Reviews"},{"key":"1757_CR9","doi-asserted-by":"publisher","first-page":"1523","DOI":"10.3390\/ijms20071523","volume":"20","author":"J Breuss","year":"2019","unstructured":"Breuss, J., A. Atanasov, and P. Uhrin. 2019. Resveratrol and its effects on the vascular system. International Journal of Molecular Sciences 20: 1523. https:\/\/doi.org\/10.3390\/ijms20071523.","journal-title":"International Journal of Molecular Sciences"},{"key":"1757_CR10","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.3390\/nu9111231","volume":"9","author":"M Yousef","year":"2017","unstructured":"Yousef, M., I. Vlachogiannis, and E. Tsiani. 2017. Effects of resveratrol against lung cancer: In vitro and in vivo studies. Nutrients 9: 1231. https:\/\/doi.org\/10.3390\/nu9111231.","journal-title":"Nutrients"},{"key":"1757_CR11","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1007\/s10787-018-00555-4","volume":"27","author":"Q Yang","year":"2019","unstructured":"Yang, Q., Y. He, X. Zhong, W. Xie, and J. Zhou. 2019. Resveratrol ameliorates gouty inflammation via upregulation of sirtuin 1 to promote autophagy in gout patients. Inflammopharmacology 27: 47\u201356. https:\/\/doi.org\/10.1007\/s10787-018-00555-4.","journal-title":"Inflammopharmacology"},{"key":"1757_CR12","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1093\/abbs\/gmu135","volume":"47","author":"C Ma","year":"2015","unstructured":"Ma, C., Y. Wang, L. Dong, M. Li, and W. Cai. 2015. Anti-inflammatory effect of resveratrol through the suppression of NF-\u03baB and JAK\/STAT signaling pathways. Acta Biochimica et Biophysica Sinica 47: 207\u2013213. https:\/\/doi.org\/10.1093\/abbs\/gmu135.","journal-title":"Acta Biochimica et Biophysica Sinica"},{"key":"1757_CR13","doi-asserted-by":"publisher","first-page":"1864","DOI":"10.7150\/ijms.44443","volume":"17","author":"E Vicari","year":"2020","unstructured":"Vicari, E., A. Arancio, V. Catania, B. Vicari, G. Sidoti, R. Castiglione, and M. Malaguarnera. 2020. Resveratrol reduces inflammation-related prostate fibrosis. International Journal of Medical Sciences 17: 1864\u20131870. https:\/\/doi.org\/10.7150\/ijms.44443.","journal-title":"International Journal of Medical Sciences"},{"key":"1757_CR14","doi-asserted-by":"publisher","first-page":"1395","DOI":"10.3892\/mmr.2017.6721","volume":"16","author":"Y Yu","year":"2017","unstructured":"Yu, Y., J. Jiang, Y. He, W. Wang, C. Shen, and B. Yang. 2017. Resveratrol improves urinary dysfunction in rats with chronic prostatitis and suppresses the activity of the stem cell factor\/c-Kit signaling pathway. Molecular Medicine Reports 16: 1395\u20131400. https:\/\/doi.org\/10.3892\/mmr.2017.6721.","journal-title":"Molecular Medicine Reports"},{"key":"1757_CR15","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1111\/j.1749-6632.2010.05842.x","volume":"1215","author":"T Walle","year":"2011","unstructured":"Walle, T. 2011. Bioavailability of resveratrol. Annals of the New York Academy of Sciences 1215: 9\u201315. https:\/\/doi.org\/10.1111\/j.1749-6632.2010.05842.x.","journal-title":"Annals of the New York Academy of Sciences"},{"key":"1757_CR16","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s13105-020-00735-3","volume":"76","author":"I Milton-Lask\u00edbar","year":"2020","unstructured":"Milton-Lask\u00edbar, I., S. G\u00f3mez-Zorita, N. Arias, N. Romo-Miguel, M. Gonz\u00e1lez, A. Fern\u00e1ndez-Quintela, and M. Portillo. 2020. Effects of resveratrol and its derivative pterostilbene on brown adipose tissue thermogenic activation and on white adipose tissue browning process. Journal of Physiology and Biochemistry 76: 269\u2013278. https:\/\/doi.org\/10.1007\/s13105-020-00735-3.","journal-title":"Journal of Physiology and Biochemistry"},{"key":"1757_CR17","first-page":"397","volume":"94","author":"B Ben Khalifa","year":"2016","unstructured":"Ben Khalifa, B., S. Naouar, W. Gazzah, B. Salem, and R. El Kamel. 2016. Predictive factors of extracorporeal shock wave lithotripsy success for urinary stones. La Tunisie Medicale 94: 397\u2013400.","journal-title":"La Tunisie Medicale"},{"key":"1757_CR18","doi-asserted-by":"publisher","first-page":"2470","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.08.019","volume":"26","author":"P Guo","year":"2017","unstructured":"Guo, P., F. Gao, T. Zhao, W. Sun, B. Wang, and Z. Li. 2017. Positive effects of extracorporeal shock wave therapy on spasticity in poststroke patients: A meta-analysis. Journal of Stroke and Cerebrovascular Diseases: The Official Journal of National Stroke Association 26: 2470\u20132476. https:\/\/doi.org\/10.1016\/j.jstrokecerebrovasdis.2017.08.019.","journal-title":"Journal of Stroke and Cerebrovascular Diseases: The Official Journal of National Stroke Association"},{"key":"1757_CR19","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1002\/nau.24017","volume":"38","author":"P Yuan","year":"2019","unstructured":"Yuan, P., D. Ma, Y. Zhang, X. Gao, Z. Liu, R. Li, T. Wang, S. Wang, J. Liu, and X. Liu. 2019. Efficacy of low-intensity extracorporeal shock wave therapy for the treatment of chronic prostatitis\/chronic pelvic pain syndrome: A systematic review and meta-analysis. Neurourology and Urodynamics 38: 1457\u20131466. https:\/\/doi.org\/10.1002\/nau.24017.","journal-title":"Neurourology and Urodynamics"},{"key":"1757_CR20","doi-asserted-by":"publisher","first-page":"1296","DOI":"10.1002\/pros.20791","volume":"68","author":"J Bernoulli","year":"2008","unstructured":"Bernoulli, J., E. Yatkin, Y. Konkol, E.M. Talvitie, R. Santti, and T. Streng. 2008. Prostatic inflammation and obstructive voiding in the adult Noble rat: Impact of the testosterone to estradiol ratio in serum. Prostate 68: 1296\u20131306. https:\/\/doi.org\/10.1002\/pros.20791.","journal-title":"Prostate"},{"key":"1757_CR21","doi-asserted-by":"publisher","first-page":"2256","DOI":"10.1002\/2211-5463.13230","volume":"11","author":"C Hou","year":"2021","unstructured":"Hou, C., L. Lu, Z. Liu, Y. Lian, and J. Xiao. 2021. Resveratrol reduces drug resistance of SCLC cells by suppressing the inflammatory microenvironment and the STAT3\/VEGF pathway. FEBS Open Bio 11: 2256\u20132265. https:\/\/doi.org\/10.1002\/2211-5463.13230.","journal-title":"FEBS Open Bio"},{"key":"1757_CR22","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-022-01704-2","author":"Y Luo","year":"2022","unstructured":"Luo, Y., X. Yu, P. Zhao, J. Huang, and X. Huang. 2022. Effects of resveratrol on tight junction proteins and the Notch1 pathway in an HT-29 cell model of inflammation induced by lipopolysaccharide. Inflammation. https:\/\/doi.org\/10.1007\/s10753-022-01704-2.","journal-title":"Inflammation"},{"key":"1757_CR23","doi-asserted-by":"publisher","first-page":"918","DOI":"10.3892\/mmr.2017.7960","volume":"17","author":"H Zeng","year":"2018","unstructured":"Zeng, H., Y. He, Y. Yu, J. Zhang, X. Zeng, F. Gong, Q. Liu, and B. Yang. 2018. Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression. Molecular Medicine Reports 17: 918\u2013924. https:\/\/doi.org\/10.3892\/mmr.2017.7960.","journal-title":"Molecular Medicine Reports"},{"key":"1757_CR24","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.etap.2017.06.025","volume":"54","author":"Y He","year":"2017","unstructured":"He, Y., H. Zeng, Y. Yu, J. Zhang, X. Duan, X. Zeng, F. Gong, Q. Liu, and B. Yang. 2017. Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis. Environmental Toxicology and Pharmacology 54: 120\u2013124. https:\/\/doi.org\/10.1016\/j.etap.2017.06.025.","journal-title":"Environmental Toxicology and Pharmacology"},{"key":"1757_CR25","doi-asserted-by":"publisher","unstructured":"Qian, X., Z. Gu, W,\u00a0 Guan, J. Qi.\u00a02021. Resveratrol could attenuate prostatic inflammation in rats with oestradiol-induced chronic prostatitis. 53:e14004. https:\/\/doi.org\/10.1111\/and.14004.","DOI":"10.1111\/and.14004"},{"key":"1757_CR26","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1002\/pros.24227","volume":"81","author":"T Igarashi","year":"2021","unstructured":"Igarashi, T., P. Tyagi, and S. Mizoguchi. 2021. Therapeutic effects of nerve growth factor-targeting therapy on bladder overactivity in rats with prostatic inflammation. Prostate 81: 1303\u20131309. https:\/\/doi.org\/10.1002\/pros.24227.","journal-title":"Prostate"},{"key":"1757_CR27","doi-asserted-by":"publisher","first-page":"1187","DOI":"10.3390\/biomedicines10051187","volume":"10","author":"M Jurczyk","year":"2022","unstructured":"Jurczyk, M., and J. Kasperczyk. 2022. Nanoparticles loaded with docetaxel and resveratrol as an advanced tool for cancer therapy. Biomedicines 10: 1187. https:\/\/doi.org\/10.3390\/biomedicines10051187.","journal-title":"Biomedicines"},{"key":"1757_CR28","doi-asserted-by":"publisher","first-page":"706","DOI":"10.3945\/an.115.011627","volume":"7","author":"S Weiskirchen","year":"2016","unstructured":"Weiskirchen, S., and R. Weiskirchen. 2016. Resveratrol: how much wine do you have to drink to stay healthy? Advances in Nutrition (Bethesda, Md.) 7: 706\u201318. https:\/\/doi.org\/10.3945\/an.115.011627.","journal-title":"Advances in Nutrition (Bethesda, Md.)"},{"key":"1757_CR29","doi-asserted-by":"publisher","first-page":"17154","DOI":"10.3390\/molecules191117154","volume":"19","author":"J Smoliga","year":"2014","unstructured":"Smoliga, J., and O. Blanchard. 2014. Enhancing the delivery of resveratrol in humans: If low bioavailability is the problem, what is the solution? Molecules (Basel, Switzerland) 19: 17154\u201317172. https:\/\/doi.org\/10.3390\/molecules191117154.","journal-title":"Molecules (Basel, Switzerland)"},{"key":"1757_CR30","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1111\/j.1749-6632.2010.05871.x","volume":"1215","author":"D Delmas","year":"2011","unstructured":"Delmas, D., V. Aires, E. Limagne, P. Dutartre, F. Mazu\u00e9, F. Ghiringhelli, and N. Latruffe. 2011. Transport, stability, and biological activity of resveratrol. Annals of the New York Academy of Sciences 1215: 48\u201359. https:\/\/doi.org\/10.1111\/j.1749-6632.2010.05871.x.","journal-title":"Annals of the New York Academy of Sciences"},{"key":"1757_CR31","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1186\/s12891-018-2204-6","volume":"19","author":"C Liao","year":"2018","unstructured":"Liao, C., G. Xie, J. Tsauo, H. Chen, and T. Liou. 2018. Efficacy of extracorporeal shock wave therapy for knee tendinopathies and other soft tissue disorders: A meta-analysis of randomized controlled trials. BMC Musculoskeletal Disorders 19: 278. https:\/\/doi.org\/10.1186\/s12891-018-2204-6.","journal-title":"BMC Musculoskeletal Disorders"},{"key":"1757_CR32","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1016\/j.juro.2011.05.073","volume":"186","author":"P Shen","year":"2011","unstructured":"Shen, P., M. Jiang, J. Yang, X. Li, Y. Li, W. Wei, Y. Dai, H. Zeng, and J. Wang. 2011. Use of ureteral stent in extracorporeal shock wave lithotripsy for upper urinary calculi: A systematic review and meta-analysis. The Journal of Urology 186: 1328\u20131335. https:\/\/doi.org\/10.1016\/j.juro.2011.05.073.","journal-title":"The Journal of Urology"},{"key":"1757_CR33","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1111\/andr.13027","volume":"9","author":"B Feng","year":"2021","unstructured":"Feng, B., Z. Dong, Y. Wang, G. Yan, E. Yang, H. Cheng, C. Liang, Z. Hao, X. Zhang, Z. Song, Z. Jiang, M. Chen, Z. Yue, and Z. Wang. 2021. Li-ESWT treatment reduces inflammation, oxidative stress, and pain via the PI3K\/AKT\/FOXO1 pathway in autoimmune prostatitis rat models. Andrology 9: 1593\u20131602. https:\/\/doi.org\/10.1111\/andr.13027.","journal-title":"Andrology"},{"key":"1757_CR34","doi-asserted-by":"publisher","first-page":"1498","DOI":"10.1002\/pros.23880","volume":"79","author":"S Jeon","year":"2019","unstructured":"Jeon, S., G. Zhu, E. Kwon, K. Lee, H. Cho, U. Ha, S. Hong, J. Lee, W. Bae, and S. Kim. 2019. Extracorporeal shock wave therapy decreases COX-2 by inhibiting TLR4-NF\u03baB pathway in a prostatitis rat model. The Prostate 79: 1498\u20131504. https:\/\/doi.org\/10.1002\/pros.23880.","journal-title":"The Prostate"},{"key":"1757_CR35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0244295","volume":"15","author":"P Birowo","year":"2020","unstructured":"Birowo, P., E. Rangganata, N. Rasyid, and W. Atmoko. 2020. Efficacy and safety of extracorporeal shockwave therapy for the treatment of chronic non-bacterial prostatitis: A systematic review and meta-analysis. PLoS ONE 15: e0244295. https:\/\/doi.org\/10.1371\/journal.pone.0244295.","journal-title":"PLoS ONE"},{"key":"1757_CR36","doi-asserted-by":"publisher","first-page":"4777","DOI":"10.3390\/ijms20194777","volume":"20","author":"HJ Wang","year":"2019","unstructured":"Wang, H.J., P. Tyagi, and Y.M. Chen. 2019. Low energy shock wave therapy inhibits inflammatory molecules and suppresses prostatic pain and hypersensitivity in a capsaicin induced prostatitis model in rats. International Journal of Molecular Science 20: 4777. https:\/\/doi.org\/10.3390\/ijms20194777.","journal-title":"International Journal of Molecular Science"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-022-01757-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10753-022-01757-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-022-01757-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,27]],"date-time":"2023-03-27T01:23:07Z","timestamp":1679880187000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10753-022-01757-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,25]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["1757"],"URL":"https:\/\/doi.org\/10.1007\/s10753-022-01757-3","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,25]]},"assertion":[{"value":"6 April 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 June 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 October 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 November 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All programs were carried out under the authorization of the Ethics Committee of the First Affiliated Hospital of Anhui Medical University.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}