{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T09:10:15Z","timestamp":1789722615134,"version":"4.0.1"},"reference-count":53,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T00:00:00Z","timestamp":1681344000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T00:00:00Z","timestamp":1681344000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s10753-023-01804-7","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T20:02:35Z","timestamp":1681329755000},"page":"1133-1143","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["LPS-aggravated Ferroptosis via Disrupting Circadian Rhythm by Bmal1\/AKT\/p53 in Sepsis-Induced Myocardial Injury"],"prefix":"10.1007","volume":"46","author":[{"given":"Hao","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kong-qin","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-tao","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Long-hai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-gao","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-hao","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"issue":"10219","key":"1804_CR1","doi-asserted-by":"publisher","first-page":"200","DOI":"10.1016\/S0140-6736(19)32989-7","volume":"395","author":"KE Rudd","year":"2020","unstructured":"Rudd, K.E., S.C. Johnson, K.M. Agesa, K.A. Shackelford, D. Tsoi, D.R. Kievlan, D.V. Colombara, K.S. Ikuta, N. Kissoon, S. Finfer, et al. 2020. Global, regional, and national sepsis incidence and mortality, 1990\u20132017: analysis for the Global Burden of Disease Study. Lancet 395 (10219): 200\u2013211.","journal-title":"Lancet"},{"issue":"1","key":"1804_CR2","doi-asserted-by":"publisher","first-page":"321","DOI":"10.3390\/ijms22010321","volume":"22","author":"AC Manetti","year":"2020","unstructured":"Manetti, A.C., A. Maiese, M.D. Paolo, A. De Matteis, R. La Russa, E. Turillazzi, P. Frati, and V. Fineschi. 2020. MicroRNAs and sepsis-induced cardiac dysfunction: a systematic review. International Journal of Molecular Sciences 22 (1): 321.","journal-title":"International Journal of Molecular Sciences"},{"issue":"4","key":"1804_CR3","doi-asserted-by":"publisher","first-page":"e91","DOI":"10.1016\/j.jemermed.2022.06.002","volume":"63","author":"RV Tucker","year":"2022","unstructured":"Tucker, R.V., K. Williams, N. Theyyunni, and C.M. Fung. 2022. Sepsis-induced cardiomyopathy detected with focused cardiac ultrasound in the emergency department. The Journal of Emergency Medicine 63 (4): e91\u2013e99.","journal-title":"The Journal of Emergency Medicine"},{"issue":"11","key":"1804_CR4","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.6502","volume":"10","author":"J Higny","year":"2022","unstructured":"Higny, J., P. Bulpa, and Y. Berners. 2022. Strain echocardiography in a sepsis-induced cardiomyopathy. Clinical Case Reports 10 (11): e6502.","journal-title":"Clinical Case Reports"},{"key":"1804_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113199","volume":"152","author":"X Xiong","year":"2022","unstructured":"Xiong, X., L. Lu, Z. Wang, J. Ma, Y. Shao, Y. Liu, M. Zhai, P. Jin, J. Yang, Q. Zheng, et al. 2022. Irisin attenuates sepsis-induced cardiac dysfunction by attenuating inflammation-induced pyroptosis through a mitochondrial ubiquitin ligase-dependent mechanism. Biomedicine & Pharmacotherapy 152: 113199.","journal-title":"Biomedicine & Pharmacotherapy"},{"issue":"19","key":"1804_CR6","doi-asserted-by":"publisher","first-page":"2992","DOI":"10.3390\/cells11192992","volume":"11","author":"Z Chen","year":"2022","unstructured":"Chen, Z., Z. Cao, F. Gui, M. Zhang, X. Wu, H. Peng, B. Yu, W. Li, F. Ai, and J. Zhang. 2022. TMEM43 protects against sepsis-induced cardiac injury via inhibiting ferroptosis in mice. Cells 11 (19): 2992.","journal-title":"Cells"},{"issue":"1","key":"1804_CR7","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1038\/s41420-022-01099-x","volume":"8","author":"H Shen","year":"2022","unstructured":"Shen, H., K. Xie, M. Li, Q. Yang, and X. Wang. 2022. N(6)-methyladenosine (m(6)A) methyltransferase METTL3 regulates sepsis-induced myocardial injury through IGF2BP1\/HDAC4 dependent manner. Cell Death Discovery 8 (1): 322.","journal-title":"Cell Death Discovery"},{"key":"1804_CR8","doi-asserted-by":"publisher","first-page":"7858746","DOI":"10.1155\/2021\/7858746","volume":"2021","author":"D Zhao","year":"2021","unstructured":"Zhao, D., C. Wang, X. Liu, N. Liu, S. Zhuang, Q. Zhang, X. Bao, S. Xu, X. Zhou, Q. Meng, et al. 2021. CircN4bp1 facilitates sepsis-induced acute respiratory distress syndrome through mediating macrophage polarization via the miR-138-5p\/EZH2 axis. Mediators of Inflammation 2021: 7858746.","journal-title":"Mediators of Inflammation"},{"key":"1804_CR9","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2021.684348","volume":"8","author":"J Li","year":"2021","unstructured":"Li, J., Y. Zhang, D. Zhang, and Y. Li. 2021. The role of long non-coding RNAs in sepsis-induced cardiac dysfunction. Frontiers in Cardiovascular Medicine 8: 684348.","journal-title":"Frontiers in Cardiovascular Medicine"},{"issue":"10","key":"1804_CR10","doi-asserted-by":"publisher","first-page":"3916","DOI":"10.1053\/j.jvca.2022.04.025","volume":"36","author":"DL Plack","year":"2022","unstructured":"Plack, D.L., O. Royer, E.J. Couture, and C.G.S. Nabzdyk. 2022. Sepsis-induced cardiomyopathy reviewed: the case for early consideration of mechanical support. Journal of cardiothoracic and vascular anesthesia 36 (10): 3916\u20133926.","journal-title":"Journal of cardiothoracic and vascular anesthesia"},{"issue":"1","key":"1804_CR11","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1186\/s13613-021-00833-5","volume":"11","author":"G Lachmann","year":"2021","unstructured":"Lachmann, G., B. Ananthasubramaniam, V.A. Wunsch, L.M. Scherfig, C. von Haefen, C. Knaak, A. Edel, L. Ehlen, B. Koller, A. Goldmann, et al. 2021. Circadian rhythms in septic shock patients. Annals of Intensive Care 11 (1): 64.","journal-title":"Annals of Intensive Care"},{"issue":"3","key":"1804_CR12","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1038\/nri3386","volume":"13","author":"C Scheiermann","year":"2013","unstructured":"Scheiermann, C., Y. Kunisaki, and P.S. Frenette. 2013. Circadian control of the immune system. Nature Reviews Immunology 13 (3): 190\u2013198.","journal-title":"Nature Reviews Immunology"},{"issue":"5","key":"1804_CR13","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1097\/SHK.0000000000001433","volume":"53","author":"C Acuna-Fernandez","year":"2020","unstructured":"Acuna-Fernandez, C., J.S. Marin, M.E. Diaz-Casado, I. Rusanova, B. Darias-Delbey, L. Perez-Guillama, J. Florido-Ruiz, and D. Acuna-Castroviejo. 2020. Daily changes in the expression of clock genes in sepsis and their relation with sepsis outcome and urinary excretion of 6-sulfatoximelatonin. Shock 53 (5): 550\u2013559.","journal-title":"Shock"},{"issue":"2","key":"1804_CR14","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3109\/07420521003769111","volume":"27","author":"Y Yamamura","year":"2010","unstructured":"Yamamura, Y., I. Yano, T. Kudo, and S. Shibata. 2010. Time-dependent inhibitory effect of lipopolysaccharide injection on Per1 and Per2 gene expression in the mouse heart and liver. Chronobiology International 27 (2): 213\u2013232.","journal-title":"Chronobiology International"},{"issue":"12","key":"1804_CR15","doi-asserted-by":"publisher","first-page":"3389","DOI":"10.1021\/acschembio.2c00445","volume":"17","author":"JP Liu","year":"2022","unstructured":"Liu, J.P., S.Y. Cen, Z. Xue, T.X. Wang, Y. Gao, J. Zheng, C. Zhang, J. Hu, S. Nie, Y. Xiong, et al. 2022. Class of disulfide compounds that suppress ferroptosis by stabilizing GPX4. ACS Chemical Biology 17 (12): 3389\u20133406.","journal-title":"ACS Chemical Biology"},{"key":"1804_CR16","doi-asserted-by":"publisher","first-page":"1010918","DOI":"10.3389\/fnut.2022.1010918","volume":"9","author":"Y Zhang","year":"2022","unstructured":"Zhang, Y., Y. Zhang, R. Yao, X. He, L. Zhao, X. Zuo, B. Lu, and Z. Pang. 2022. Ferroptosis-related differentially expressed genes serve as new biomarkers in ischemic stroke and identification of therapeutic drugs. Frontiers in Nutrition 9: 1010918.","journal-title":"Frontiers in Nutrition"},{"key":"1804_CR17","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1016\/j.freeradbiomed.2020.08.009","volume":"160","author":"N Li","year":"2020","unstructured":"Li, N., W. Wang, H. Zhou, Q. Wu, M. Duan, C. Liu, H. Wu, W. Deng, D. Shen, and Q. Tang. 2020. Ferritinophagy-mediated ferroptosis is involved in sepsis-induced cardiac injury. Free Radical Biology & Medicine 160: 303\u2013318.","journal-title":"Free Radical Biology & Medicine"},{"key":"1804_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109540","volume":"120","author":"J Hu","year":"2019","unstructured":"Hu, J., Y. Xue, K. Tang, J. Fan, J. Du, W. Li, S. Chen, C. Liu, W. Ji, J. Liang, et al. 2019. The protective effects of hydrogen sulfide on the myocardial ischemia via regulating Bmal1. Biomedicine & Pharmacotherapy 120: 109540.","journal-title":"Biomedicine & Pharmacotherapy"},{"issue":"38","key":"1804_CR19","doi-asserted-by":"publisher","first-page":"42791","DOI":"10.1021\/acsami.2c00707","volume":"14","author":"C Wu","year":"2022","unstructured":"Wu, C., Z. Shen, Y. Lu, F. Sun, and H. Shi. 2022. p53 promotes ferroptosis in macrophages treated with Fe(3)O(4) nanoparticles. ACS Applied Materials & Interfaces 14 (38): 42791\u201342803.","journal-title":"ACS Applied Materials & Interfaces"},{"issue":"5","key":"1804_CR20","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1080\/17435390.2020.1731857","volume":"14","author":"YH Pei","year":"2020","unstructured":"Pei, Y.H., J. Chen, X. Wu, Y. He, W. Qin, S.Y. He, N. Chang, H. Jiang, J. Zhou, P. Yu, et al. 2020. LncRNA PEAMIR inhibits apoptosis and inflammatory response in PM2.5 exposure aggravated myocardial ischemia\/reperfusion injury as a competing endogenous RNA of miR-29b-3p. Nanotoxicology 14 (5): 638\u2013653.","journal-title":"Nanotoxicology"},{"key":"1804_CR21","doi-asserted-by":"publisher","first-page":"1232103","DOI":"10.1155\/2016\/1232103","volume":"2016","author":"YH Pei","year":"2016","unstructured":"Pei, Y.H., J. Chen, L. Xie, X.M. Cai, R.H. Yang, X. Wang, and J.B. Gong. 2016. Hydroxytyrosol protects against myocardial ischemia\/reperfusion injury through a PI3K\/Akt-dependent mechanism. Mediators of Inflammation 2016: 1232103.","journal-title":"Mediators of Inflammation"},{"key":"1804_CR22","doi-asserted-by":"publisher","first-page":"963689720945677","DOI":"10.1177\/0963689720945677","volume":"29","author":"C Zhang","year":"2020","unstructured":"Zhang, C., H. Wang, G.C.F. Chan, Y. Zhou, X. Lai, and M. Lian. 2020. Extracellular vesicles derived from human umbilical cord mesenchymal stromal cells protect cardiac cells against hypoxia\/reoxygenation injury by inhibiting endoplasmic reticulum stress via activation of the PI3K\/Akt pathway. Cell Transplantation 29: 963689720945677.","journal-title":"Cell Transplantation"},{"issue":"3","key":"1804_CR23","doi-asserted-by":"crossref","first-page":"1523","DOI":"10.1109\/TCBB.2020.3040368","volume":"19","author":"C Wang","year":"2022","unstructured":"Wang, C., H. Liu, Z. Miao, and J. Zhou. 2022. Circadian rhythm regulated by tumor suppressor p53 and time delay in unstressed cells. IEEE\/ACM Transactions on Computational Biology and Bioinformatics 19 (3): 1523\u20131530.","journal-title":"IEEE\/ACM Transactions on Computational Biology and Bioinformatics"},{"issue":"9","key":"1804_CR24","doi-asserted-by":"publisher","first-page":"8067","DOI":"10.18632\/aging.103124","volume":"12","author":"Y Zhang","year":"2020","unstructured":"Zhang, Y., A. Devocelle, L. Souza, A. Foudi, S. Tenreira Bento, C. Desterke, R. Sherrard, A. Ballesta, R. Adam, J. Giron-Michel, et al. 2020. BMAL1 knockdown triggers different colon carcinoma cell fates by altering the delicate equilibrium between AKT\/mTOR and P53\/P21 pathways. Aging (Albany NY) 12 (9): 8067\u20138083.","journal-title":"Aging (Albany NY)"},{"issue":"6","key":"1804_CR25","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1111\/j.1471-4159.2009.05931.x","volume":"108","author":"ML Ko","year":"2009","unstructured":"Ko, M.L., K. Jian, L. Shi, and G.Y. Ko. 2009. Phosphatidylinositol 3 kinase-Akt signaling serves as a circadian output in the retina. Journal of Neurochemistry 108 (6): 1607\u20131620.","journal-title":"Journal of Neurochemistry"},{"issue":"6","key":"1804_CR26","doi-asserted-by":"publisher","first-page":"2109","DOI":"10.3892\/or.2013.2381","volume":"29","author":"CH Jung","year":"2013","unstructured":"Jung, C.H., E.M. Kim, J.K. Park, S.G. Hwang, S.K. Moon, W.J. Kim, and H.D. Um. 2013. Bmal1 suppresses cancer cell invasion by blocking the phosphoinositide 3-kinase-Akt-MMP-2 signaling pathway. Oncology Reports 29 (6): 2109\u20132113.","journal-title":"Oncology Reports"},{"key":"1804_CR27","doi-asserted-by":"publisher","first-page":"30922","DOI":"10.1038\/srep30922","volume":"6","author":"R Xu","year":"2016","unstructured":"Xu, R., Y. Sun, Z. Chen, Y. Yao, and G. Ma. 2016. Hypoxic preconditioning inhibits hypoxia-induced apoptosis of cardiac progenitor cells via the PI3K\/Akt-DNMT1-p53 pathway. Science and Reports 6: 30922.","journal-title":"Science and Reports"},{"key":"1804_CR28","doi-asserted-by":"publisher","first-page":"487","DOI":"10.3389\/fncel.2019.00487","volume":"13","author":"M Malcolm","year":"2019","unstructured":"Malcolm, M., L. Saad, L.G. Penazzi, and E. Garbarino-Pico. 2019. Processing bodies oscillate in neuro 2A cells. Frontiers in Cellular Neuroscience 13: 487.","journal-title":"Frontiers in Cellular Neuroscience"},{"key":"1804_CR29","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.656086","volume":"8","author":"WL Xu","year":"2021","unstructured":"Xu, W.L., S. Liu, N. Li, L.F. Ye, M. Zha, C.Y. Li, Y. Zhao, Q. Pu, J.J. Bao, X.J. Chen, et al. 2021. Quercetin antagonizes glucose fluctuation induced renal injury by inhibiting aerobic glycolysis via HIF-1alpha\/miR-210\/ISCU\/FeS pathway. Frontiers in Medicine 8: 656086.","journal-title":"Frontiers in Medicine"},{"key":"1804_CR30","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.13983","volume":"10","author":"S Cui","year":"2022","unstructured":"Cui, S., K. Niu, Y. Xie, S. Li, W. Zhu, L. Yu, and H. Tan. 2022. Screening of potential key ferroptosis-related genes in sepsis. PeerJ 10: e13983.","journal-title":"PeerJ"},{"key":"1804_CR31","doi-asserted-by":"publisher","first-page":"956361","DOI":"10.3389\/fimmu.2022.956361","volume":"13","author":"XL Lei","year":"2022","unstructured":"Lei, X.L., G.Y. Zhao, R. Guo, and N. Cui. 2022. Ferroptosis in sepsis: the mechanism, the role and the therapeutic potential. Frontiers in Immunology 13: 956361.","journal-title":"Frontiers in Immunology"},{"issue":"11","key":"1804_CR32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0167004","volume":"11","author":"NP Boeddha","year":"2016","unstructured":"Boeddha, N.P., G.J. Driessen, M.H. Cnossen, J.A. Hazelzet, and M. Emonts. 2016. Circadian variation of plasminogen-activator-inhibitor-1 levels in children with meningococcal sepsis. PLoS ONE 11 (11): e0167004.","journal-title":"PLoS ONE"},{"issue":"7","key":"1804_CR33","doi-asserted-by":"publisher","first-page":"1144","DOI":"10.1513\/AnnalsATS.201602-125FR","volume":"13","author":"KK Truong","year":"2016","unstructured":"Truong, K.K., M.T. Lam, M.A. Grandner, C.S. Sassoon, and A. Malhotra. 2016. Timing matters: circadian rhythm in sepsis, obstructive lung disease, obstructive sleep apnea, and cancer. Annals of the American Thoracic Society 13 (7): 1144\u20131154.","journal-title":"Annals of the American Thoracic Society"},{"key":"1804_CR34","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.948290","volume":"13","author":"Q Li","year":"2022","unstructured":"Li, Q., Z. Chen, C. Yang, L. Wang, J. Ma, T. He, H. Li, and Z. Quan. 2022. Role of ferroptosis-associated genes in ankylosing spondylitis and immune cell infiltration. Frontiers in Genetics 13: 948290.","journal-title":"Frontiers in Genetics"},{"key":"1804_CR35","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.884362","volume":"13","author":"J Zhang","year":"2022","unstructured":"Zhang, J., Y. Zheng, Y. Wang, J. Wang, A. Sang, X. Song, and X. Li. 2022. YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis. Frontiers in Immunology 13: 884362.","journal-title":"Frontiers in Immunology"},{"key":"1804_CR36","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.13757","volume":"10","author":"Q Chen","year":"2022","unstructured":"Chen, Q., L. Liu, and S. Ni. 2022. Screening of ferroptosis-related genes in sepsis-induced liver failure and analysis of immune correlation. PeerJ 10: e13757.","journal-title":"PeerJ"},{"key":"1804_CR37","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.109162","volume":"112","author":"W Qiu","year":"2022","unstructured":"Qiu, W., S. An, T. Wang, J. Li, B. Yu, Z. Zeng, Z. Chen, B. Lin, X. Lin, and Y. Gao. 2022. Melatonin suppresses ferroptosis via activation of the Nrf2\/HO-1 signaling pathway in the mouse model of sepsis-induced acute kidney injury. International Immunopharmacology 112: 109162.","journal-title":"International Immunopharmacology"},{"issue":"24","key":"1804_CR38","doi-asserted-by":"publisher","first-page":"3453","DOI":"10.2174\/1381612821666150706105602","volume":"21","author":"CJ Madrid-Navarro","year":"2015","unstructured":"Madrid-Navarro, C.J., R. Sanchez-Galvez, A. Martinez-Nicolas, R. Marina, J.A. Garcia, J.A. Madrid, and M.A. Rol. 2015. Disruption of circadian rhythms and delirium, sleep impairment and sepsis in critically ill patients. Potential therapeutic implications for increased light-dark contrast and melatonin therapy in an ICU environment. Current Pharmaceutical Design 21 (24): 3453\u20133468.","journal-title":"Current Pharmaceutical Design"},{"issue":"1","key":"1804_CR39","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1248\/bpb.b20-00694","volume":"44","author":"H Yoshioka","year":"2021","unstructured":"Yoshioka, H., S. Tominaga, M. Nishikawa, Y. Shinohara, M. Nakao, M. Yoshikawa, T. Maeda, and N. Miura. 2021. Different renal chronotoxicity of bromobenzene and its intermediate metabolites in mice. Biological and Pharmaceutical Bulletin 44 (1): 150\u2013153.","journal-title":"Biological and Pharmaceutical Bulletin"},{"key":"1804_CR40","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.773181","volume":"11","author":"ML Mul Fedele","year":"2021","unstructured":"Mul Fedele, M.L., C.A. Senna, I. Aiello, D.A. Golombek, and N. Paladino. 2021. Circadian rhythms in bacterial sepsis pathology: what we know and what we should know. Frontiers in Cellular and Infection Microbiology 11: 773181.","journal-title":"Frontiers in Cellular and Infection Microbiology"},{"issue":"8","key":"1804_CR41","doi-asserted-by":"publisher","first-page":"4750","DOI":"10.1128\/IAI.00287-06","volume":"74","author":"J Liu","year":"2006","unstructured":"Liu, J., G. Malkani, X. Shi, M. Meyer, S. Cunningham-Runddles, X. Ma, and Z.S. Sun. 2006. The circadian clock period 2 gene regulates gamma interferon production of NK cells in host response to lipopolysaccharide-induced endotoxic shock. Infection and Immunity 74 (8): 4750\u20134756.","journal-title":"Infection and Immunity"},{"issue":"1","key":"1804_CR42","doi-asserted-by":"publisher","first-page":"193","DOI":"10.4049\/jimmunol.1701677","volume":"201","author":"EL Heipertz","year":"2018","unstructured":"Heipertz, E.L., J. Harper, C.A. Lopez, E. Fikrig, M.E. Hughes, and W.E. Walker. 2018. Circadian rhythms influence the severity of sepsis in mice via a TLR2-dependent, leukocyte-intrinsic mechanism. The Journal of Immunology 201 (1): 193\u2013201.","journal-title":"The Journal of Immunology"},{"issue":"1","key":"1804_CR43","doi-asserted-by":"publisher","first-page":"2745","DOI":"10.1038\/s41467-021-22961-z","volume":"12","author":"SS Geiger","year":"2021","unstructured":"Geiger, S.S., J. Traba, N. Richoz, T.K. Farley, S.R. Brooks, F. Petermann, L. Wang, F.J. Gonzalez, M.N. Sack, and R.M. Siegel. 2021. Feeding-induced resistance to acute lethal sepsis is dependent on hepatic BMAL1 and FXR signalling. Nature Communications 12 (1): 2745.","journal-title":"Nature Communications"},{"issue":"23","key":"1804_CR44","doi-asserted-by":"publisher","first-page":"7231","DOI":"10.1073\/pnas.1501327112","volume":"112","author":"AM Curtis","year":"2015","unstructured":"Curtis, A.M., C.T. Fagundes, G. Yang, E.M. Palsson-McDermott, P. Wochal, A.F. McGettrick, N.H. Foley, J.O. Early, L. Chen, H. Zhang, et al. 2015. Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. Proceedings of the National Academy of Sciences 112 (23): 7231\u20137236.","journal-title":"Proceedings of the National Academy of Sciences"},{"issue":"7","key":"1804_CR45","doi-asserted-by":"publisher","first-page":"eaaw2238","DOI":"10.1126\/sciadv.aaw2238","volume":"5","author":"M Yang","year":"2019","unstructured":"Yang, M., P. Chen, J. Liu, S. Zhu, G. Kroemer, D.J. Klionsky, M.T. Lotze, H.J. Zeh, R. Kang, and D. Tang. 2019. Clockophagy is a novel selective autophagy process favoring ferroptosis. Science Advances 5 (7): eaaw2238.","journal-title":"Science Advances"},{"key":"1804_CR46","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2022.101360","volume":"18","author":"Y Yang","year":"2022","unstructured":"Yang, Y., H. Tang, J. Zheng, and K. Yang. 2022. The PER1\/HIF-1alpha negative feedback loop promotes ferroptosis and inhibits tumor progression in oral squamous cell carcinoma. Translational Oncology 18: 101360.","journal-title":"Translational Oncology"},{"issue":"3","key":"1804_CR47","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/j.bbrc.2020.02.142","volume":"525","author":"Y Liu","year":"2020","unstructured":"Liu, Y., Y. Wang, J. Liu, R. Kang, and D. Tang. 2020. The circadian clock protects against ferroptosis-induced sterile inflammation. Biochemical and Biophysical Research Communications 525 (3): 620\u2013625.","journal-title":"Biochemical and Biophysical Research Communications"},{"issue":"1","key":"1804_CR48","doi-asserted-by":"publisher","first-page":"19082","DOI":"10.1038\/s41598-019-55663-0","volume":"9","author":"MC Beker","year":"2019","unstructured":"Beker, M.C., B. Caglayan, A.B. Caglayan, T. Kelestemur, E. Yalcin, A. Caglayan, U. Kilic, A.T. Baykal, R.J. Reiter, and E. Kilic. 2019. Interaction of melatonin and Bmal1 in the regulation of PI3K\/AKT pathway components and cellular survival. Science and Reports 9 (1): 19082.","journal-title":"Science and Reports"},{"key":"1804_CR49","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.841410","volume":"13","author":"S Li","year":"2022","unstructured":"Li, S., Z. Lei, X. Yang, M. Zhao, Y. Hou, D. Wang, S. Tang, J. Li, and J. Yu. 2022. Propofol protects myocardium from ischemia\/reperfusion injury by inhibiting ferroptosis through the AKT\/p53 signaling pathway. Frontiers in Pharmacology 13: 841410.","journal-title":"Frontiers in Pharmacology"},{"key":"1804_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2019.105782","volume":"75","author":"LJ Sun","year":"2019","unstructured":"Sun, L.J., W. Qiao, Y.J. Xiao, L. Cui, X. Wang, and W.D. Ren. 2019. Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K\/AKT\/NF-kappaB pathway. International Immunopharmacology 75: 105782.","journal-title":"International Immunopharmacology"},{"key":"1804_CR51","doi-asserted-by":"crossref","unstructured":"Zhang, L., B. Li, W. Li, J. Jiang, W. Chen, H. Yang, and D. Pan. 2022. miR-107 attenuates sepsis-induced myocardial injury by targeting PTEN and activating the PI3K\/AKT signaling pathway. Cells Tissues Organs.","DOI":"10.1159\/000525476"},{"issue":"6","key":"1804_CR52","doi-asserted-by":"publisher","first-page":"371","DOI":"10.3892\/etm.2022.11298","volume":"23","author":"H Zhang","year":"2022","unstructured":"Zhang, H., X. Wu, Y. Tao, and G. Lu. 2022. Berberine attenuates sepsis-induced cardiac dysfunction by upregulating the Akt\/eNOS pathway in mice. Experimental and Therapeutic Medicine 23 (6): 371.","journal-title":"Experimental and Therapeutic Medicine"},{"key":"1804_CR53","doi-asserted-by":"crossref","first-page":"e23261","DOI":"10.1002\/jbt.23261","volume":"37","author":"F Yarmohammadi","year":"2022","unstructured":"Yarmohammadi, F., Z. Ebrahimian, and G. Karimi. 2022. MicroRNAs target the PI3K\/Akt\/p53 and the Sirt1\/Nrf2 signaling pathways in doxorubicin-induced cardiotoxicity. Journal of Biochemical and Molecular Toxicology 37: e23261.","journal-title":"Journal of Biochemical and Molecular Toxicology"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-023-01804-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10753-023-01804-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-023-01804-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T01:14:21Z","timestamp":1729214061000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10753-023-01804-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,13]]},"references-count":53,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["1804"],"URL":"https:\/\/doi.org\/10.1007\/s10753-023-01804-7","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,13]]},"assertion":[{"value":"20 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 March 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}