{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:06:21Z","timestamp":1777633581062,"version":"3.51.4"},"reference-count":60,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T00:00:00Z","timestamp":1690243200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100018537","name":"National Science and Technology Major Project","doi-asserted-by":"publisher","award":["2018ZX10723203"],"award-info":[{"award-number":["2018ZX10723203"]}],"id":[{"id":"10.13039\/501100018537","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81800506"],"award-info":[{"award-number":["81800506"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81970523"],"award-info":[{"award-number":["81970523"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","award":["2019JJ40494"],"award-info":[{"award-number":["2019JJ40494"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","award":["2020JJ5886"],"award-info":[{"award-number":["2020JJ5886"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","award":["2021JJ70148"],"award-info":[{"award-number":["2021JJ70148"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","award":["2020JJ4906"],"award-info":[{"award-number":["2020JJ4906"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of\u00a0Hunan Province","doi-asserted-by":"publisher","award":["2020JJ4877"],"award-info":[{"award-number":["2020JJ4877"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s10753-023-01854-x","type":"journal-article","created":{"date-parts":[[2023,7,25]],"date-time":"2023-07-25T08:01:59Z","timestamp":1690272119000},"page":"1602-1611","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["The Hepatic Nerves Regulated Inflammatory Effect in the Process of Liver Injury: Is Nerve the Key Treating Target for Liver Inflammation?"],"prefix":"10.1007","volume":"46","author":[{"given":"Kaili","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zebing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhihong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Panpan","family":"Yi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yayu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meifang","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Quan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingwang","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,7,25]]},"reference":[{"key":"1854_CR1","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.1002\/hep.32055","volume":"74","author":"BM Miller","year":"2021","unstructured":"Miller, B.M., I.M. Oderberg, and W. Goessling. 2021. Hepatic nervous system in development, regeneration, and disease. Hepatology 74: 3513\u20133522.","journal-title":"Hepatology"},{"key":"1854_CR2","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.1002\/jcp.25307","volume":"231","author":"MR Pereira","year":"2016","unstructured":"Pereira, M.R., and P.E. Leite. 2016. The involvement of parasympathetic and sympathetic nerve in the inflammatory reflex. Journal of Cellular Physiology 231: 1862\u20131869.","journal-title":"Journal of Cellular Physiology"},{"key":"1854_CR3","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2119\/molmed.2014.00143","volume":"20","author":"N Terrando","year":"2015","unstructured":"Terrando, N., T. Yang, J.K. Ryu, P.T. Newton, C. Monaco, M. Feldmann, et al. 2015. Stimulation of the alpha7 nicotinic acetylcholine receptor protects against neuroinflammation after tibia fracture and endotoxemia in mice. Molecular Medicine 20: 667\u2013675.","journal-title":"Molecular Medicine"},{"issue":"3","key":"1854_CR4","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1159\/000362240","volume":"22","author":"E Sanchez-Aleman","year":"2015","unstructured":"Sanchez-Aleman, E., A. Quintanar-Stephano, G. Escobedo, R. Campos-Esparza Mdel, R. Campos-Rodriguez, and J. Ventura-Juarez. 2015. Vagotomy induces deregulation of the inflammatory response during the development of amoebic liver abscess in hamsters. NeuroImmunoModulation 22 (3): 166\u2013180.","journal-title":"NeuroImmunoModulation"},{"key":"1854_CR5","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1038\/ni1229","volume":"6","author":"WJ de Jonge","year":"2005","unstructured":"de Jonge, W.J., E.P. van der Zanden, F.O. The, M.F. Bijlsma, D.J. van Westerloo, R.J. Bennink, et al. 2005. Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway. Nature Immunology 6: 844\u2013851.","journal-title":"Nature Immunology"},{"key":"1854_CR6","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1007\/s00535-016-1304-z","volume":"52","author":"T Nishio","year":"2017","unstructured":"Nishio, T., K. Taura, K. Iwaisako, Y. Koyama, K. Tanabe, G. Yamamoto, et al. 2017. Hepatic vagus nerve regulates Kupffer cell activation via alpha7 nicotinic acetylcholine receptor in nonalcoholic steatohepatitis. Journal of Gastroenterology 52: 965\u2013976.","journal-title":"Journal of Gastroenterology"},{"key":"1854_CR7","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.jhep.2012.02.028","volume":"57","author":"A Leroux","year":"2012","unstructured":"Leroux, A., G. Ferrere, V. Godie, F. Cailleux, M.L. Renoud, F. Gaudin, et al. 2012. Toxic lipids stored by Kupffer cells correlates with their pro-inflammatory phenotype at an early stage of steatohepatitis. Journal of Hepatology 57: 141\u2013149.","journal-title":"Journal of Hepatology"},{"key":"1854_CR8","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1056\/NEJMra1503519","volume":"377","author":"AM Diehl","year":"2017","unstructured":"Diehl, A.M., and C. Day. 2017. Cause, pathogenesis, and treatment of nonalcoholic steatohepatitis. New England Journal of Medicine 377: 2063\u20132072.","journal-title":"New England Journal of Medicine"},{"key":"1854_CR9","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/path.4829","volume":"241","author":"JK Lau","year":"2017","unstructured":"Lau, J.K., X. Zhang, and J. Yu. 2017. Animal models of non-alcoholic fatty liver disease: Current perspectives and recent advances. The Journal of Pathology 241: 36\u201344.","journal-title":"The Journal of Pathology"},{"key":"1854_CR10","doi-asserted-by":"crossref","first-page":"1836","DOI":"10.1002\/hep.24001","volume":"52","author":"H Tilg","year":"2010","unstructured":"Tilg, H., and A.R. Moschen. 2010. Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis. Hepatology 52: 1836\u20131846.","journal-title":"Hepatology"},{"key":"1854_CR11","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/nrendo.2012.189","volume":"8","author":"VA Pavlov","year":"2012","unstructured":"Pavlov, V.A., and K.J. Tracey. 2012. The vagus nerve and the inflammatory reflex\u2013linking immunity and metabolism. Nature Reviews. Endocrinology 8: 743\u2013754.","journal-title":"Nature Reviews. Endocrinology"},{"key":"1854_CR12","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.pharmthera.2010.02.002","volume":"126","author":"GW Lambert","year":"2010","unstructured":"Lambert, G.W., N.E. Straznicky, E.A. Lambert, J.B. Dixon, and M.P. Schlaich. 2010. Sympathetic nervous activation in obesity and the metabolic syndrome\u2013causes, consequences and therapeutic implications. Pharmacology & Therapeutics 126: 159\u2013172.","journal-title":"Pharmacology & Therapeutics"},{"key":"1854_CR13","doi-asserted-by":"crossref","first-page":"4565","DOI":"10.1113\/JP277994","volume":"597","author":"C Hurr","year":"2019","unstructured":"Hurr, C., H. Simonyan, D.A. Morgan, K. Rahmouni, and C.N. Young. 2019. Liver sympathetic denervation reverses obesity-induced hepatic steatosis. Journal of Physiology 597: 4565\u20134580.","journal-title":"Journal of Physiology"},{"key":"1854_CR14","doi-asserted-by":"crossref","unstructured":"Lyudmila, V., S.I. Borovikova. 2019.Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature 458\u201362.","DOI":"10.1038\/35013070"},{"key":"1854_CR15","first-page":"R328","volume":"321","author":"H Torres","year":"2021","unstructured":"Torres, H., C. Huesing, D.H. Burk, A.J.R. Molinas, W.L. Neuhuber, H.R. Berthoud, et al. 2021. Sympathetic innervation of the mouse kidney and liver arising from prevertebral ganglia. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology 321: R328\u2013R337.","journal-title":"American Journal of Physiology: Regulatory, Integrative and Comparative Physiology"},{"key":"1854_CR16","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1002\/cphy.c120018","volume":"3","author":"KJ Jensen","year":"2013","unstructured":"Jensen, K.J., G. Alpini, and S. Glaser. 2013. Hepatic nervous system and neurobiology of the liver. Comprehensive Physiology 3: 655\u2013665.","journal-title":"Comprehensive Physiology"},{"key":"1854_CR17","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/ar.a.20087","volume":"280","author":"RS McCuskey","year":"2004","unstructured":"McCuskey, R.S. 2004. Anatomy of efferent hepatic nerves. The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology 280: 821\u2013826.","journal-title":"The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology"},{"key":"1854_CR18","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/nn.4477","volume":"20","author":"VA Pavlov","year":"2017","unstructured":"Pavlov, V.A., and K.J. Tracey. 2017. Neural regulation of immunity: Molecular mechanisms and clinical translation. Nature Neuroscience 20: 156\u2013166.","journal-title":"Nature Neuroscience"},{"key":"1854_CR19","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1152\/ajpgi.00195.2018","volume":"315","author":"CN Metz","year":"2018","unstructured":"Metz, C.N., and V.A. Pavlov. 2018. Vagus nerve cholinergic circuitry to the liver and the gastrointestinal tract in the neuroimmune communicatome. American Journal of Physiology. Gastrointestinal and Liver Physiology 315: 651\u2013658.","journal-title":"American Journal of Physiology. Gastrointestinal and Liver Physiology"},{"key":"1854_CR20","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/j.immuni.2017.06.008","volume":"46","author":"SS Chavan","year":"2017","unstructured":"Chavan, S.S., V.A. Pavlov, and K.J. Tracey. 2017. Mechanisms and therapeutic relevance of neuro-immune communication. Immunity 46: 927\u2013942.","journal-title":"Immunity"},{"issue":"6","key":"1854_CR21","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/j.1365-2796.2009.02098.x","volume":"265","author":"M Rosas-Ballina","year":"2009","unstructured":"Rosas-Ballina, M., and K.J. Tracey. 2009. Cholinergic control of inflammation. Journal of Internal Medicine 265 (6): 663\u2013679.","journal-title":"Journal of Internal Medicine"},{"key":"1854_CR22","doi-asserted-by":"crossref","unstructured":"Bonaz, B., V. Sinniger, S. Pellissier. 2019. Vagus nerve stimulation at the interface of brain-gut interactions.\u00a0Cold Spring Harbor Perspectives in Medicine\u00a09(8).","DOI":"10.1101\/cshperspect.a034199"},{"key":"1854_CR23","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.bbi.2019.06.041","volume":"81","author":"RC Fonseca","year":"2019","unstructured":"Fonseca, R.C., G.S. Bassi, C.C. Brito, L.B. Rosa, B.A. David, A.M. Araujo, et al. 2019. Vagus nerve regulates the phagocytic and secretory activity of resident macrophages in the liver. Brain, Behavior, and Immunity 81: 444\u2013454.","journal-title":"Brain, Behavior, and Immunity"},{"key":"1854_CR24","doi-asserted-by":"crossref","unstructured":"Fernandez, R., G. Nardocci, C. Navarro, E.P. Reyes, C. Acuna-Castillo, P.P. Cortes. 2014. Neural reflex regulation of systemic inflammation: potential new targets for sepsis therapy.\u00a0Frontiers in Physiology\u00a05:489\u201398.","DOI":"10.3389\/fphys.2014.00489"},{"key":"1854_CR25","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1038\/s12276-022-00921-x","volume":"55","author":"HH Kim","year":"2023","unstructured":"Kim, H.H., Y.R. Shim, S.E. Choi, M.H. Kim, G. Lee, H.J. You, et al. 2023. Catecholamine induces Kupffer cell apoptosis via growth differentiation factor 15 in alcohol-associated liver disease. Experimental & Molecular Medicine 55: 158\u2013170.","journal-title":"Experimental & Molecular Medicine"},{"key":"1854_CR26","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1136\/gut.2004.058818","volume":"54","author":"Y Chida","year":"2005","unstructured":"Chida, Y., N. Sudo, A. Takaki, and C. Kubo. 2005. The hepatic sympathetic nerve plays a critical role in preventing Fas induced liver injury in mice. Gut 54: 994\u20131002.","journal-title":"Gut"},{"key":"1854_CR27","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1146\/annurev-immunol-042617-053158","volume":"36","author":"VA Pavlov","year":"2018","unstructured":"Pavlov, V.A., S.S. Chavan, and K.J. Tracey. 2018. Molecular and functional neuroscience in immunity. Annual Review of Immunology 36: 783\u2013812.","journal-title":"Annual Review of Immunology"},{"key":"1854_CR28","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0065-1281(98)80011-1","volume":"100","author":"II Stoyanova","year":"1998","unstructured":"Stoyanova, I.I., and M.V. Gulubova. 1998. Peptidergic nerve fibres in the human liver. Acta Histochemica 100: 245\u2013256.","journal-title":"Acta Histochemica"},{"key":"1854_CR29","doi-asserted-by":"crossref","first-page":"137","DOI":"10.4254\/wjh.v6.i3.137","volume":"6","author":"LA Streba","year":"2014","unstructured":"Streba, L.A., C.C. Vere, A.G. Ionescu, C.T. Streba, and I. Rogoveanu. 2014. Role of intrahepatic innervation in regulating the activity of liver cells. World Journal of Hepatology 6: 137\u2013143.","journal-title":"World Journal of Hepatology"},{"key":"1854_CR30","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1078\/0065-1281-00568","volume":"102","author":"II Stoyanova","year":"2000","unstructured":"Stoyanova, I.I., and M.V. Gulubova. 2000. Immunocytochemical study on the liver innervation in patients with cirrhosis. Acta Histochemica 102: 391\u2013402.","journal-title":"Acta Histochemica"},{"key":"1854_CR31","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1053\/j.gastro.2014.06.043","volume":"147","author":"F Marra","year":"2014","unstructured":"Marra, F., and F. Tacke. 2014. Roles for chemokines in liver disease. Gastroenterology 147: 577\u2013594.","journal-title":"Gastroenterology"},{"key":"1854_CR32","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41467-020-20170-8","volume":"12","author":"M Liu","year":"2021","unstructured":"Liu, M., S. Cao, L. He, J. Gao, J.P. Arab, H. Cui, et al. 2021. Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis. Nature Communications 12: 14.","journal-title":"Nature Communications"},{"key":"1854_CR33","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.4049\/jimmunol.174.2.1055","volume":"174","author":"M Heydtmann","year":"2005","unstructured":"Heydtmann, M., P.F. Lalor, J.A. Eksteen, S.G. Hubscher, M. Briskin, and D.H. Adams. 2005. CXC chemokine ligand 16 promotes integrin-mediated adhesion of liver-infiltrating lymphocytes to cholangiocytes and hepatocytes within the inflamed human liver. The Journal of Immunology 174: 1055\u20131062.","journal-title":"The Journal of Immunology"},{"key":"1854_CR34","doi-asserted-by":"crossref","unstructured":"Nagata, N., G. Chen, L. Xu, and H. Ando. 2022. An update on the chemokine system in the development of NAFLD. Medicina (Kaunas) 58(761\u2013771).","DOI":"10.3390\/medicina58060761"},{"key":"1854_CR35","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1182\/blood-2008-07-170787","volume":"113","author":"L Landsman","year":"2009","unstructured":"Landsman, L., L. Bar-On, A. Zernecke, K.W. Kim, R. Krauthgamer, E. Shagdarsuren, et al. 2009. CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood 113: 963\u2013972.","journal-title":"Blood"},{"key":"1854_CR36","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-981-10-8684-7_4","volume":"1061","author":"YS Roh","year":"2018","unstructured":"Roh, Y.S., and E. Seki. 2018. Chemokines and chemokine receptors in the development of NAFLD. Advances in Experimental Medicine and Biology 1061: 45\u201353.","journal-title":"Advances in Experimental Medicine and Biology"},{"key":"1854_CR37","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1002\/hep.23795","volume":"52","author":"T Aoyama","year":"2010","unstructured":"Aoyama, T., S. Inokuchi, D.A. Brenner, and E. Seki. 2010. CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. Hepatology 52: 1390\u20131400.","journal-title":"Hepatology"},{"key":"1854_CR38","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1097\/TP.0000000000002690","volume":"103","author":"S Chaudhry","year":"2019","unstructured":"Chaudhry, S., J. Emond, and A. Griesemer. 2019. Immune cell trafficking to the liver. Transplantation 103: 1323\u20131337.","journal-title":"Transplantation"},{"key":"1854_CR39","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.jss.2014.12.006","volume":"194","author":"AN Kandilis","year":"2015","unstructured":"Kandilis, A.N., I.P. Papadopoulou, J. Koskinas, G. Sotiropoulos, and D.G. Tiniakos. 2015. Liver innervation and hepatic function: New insights. Journal of Surgical Research 194: 511\u2013519.","journal-title":"Journal of Surgical Research"},{"key":"1854_CR40","doi-asserted-by":"crossref","unstructured":"Ishii, K., M. Shimizu, H. Karube, A. Shibuya, H. Shibata, M. Okudaira, H. Nagata, and M. Tsuchiya. 1992. Inhibitory effect of noradrenaline on acute liver injury induced by carbon tetrachloride in the rat. Journal of Autonomic Nervous System.","DOI":"10.1016\/0165-1838(92)90246-D"},{"key":"1854_CR41","doi-asserted-by":"crossref","first-page":"3190617","DOI":"10.1155\/2016\/3190617","volume":"2016","author":"JC Lin","year":"2016","unstructured":"Lin, J.C., Y.J. Peng, S.Y. Wang, M.J. Lai, T.H. Young, D.M. Salter, et al. 2016. Sympathetic nervous system control of carbon tetrachloride-induced oxidative stress in liver through alpha-adrenergic signaling. Oxidative Medicine and Cellular Longevity 2016: 3190617.","journal-title":"Oxidative Medicine and Cellular Longevity"},{"key":"1854_CR42","first-page":"18","volume":"10","author":"JC Lin","year":"2015","unstructured":"Lin, J.C., Y.J. Peng, S.Y. Wang, T.H. Young, D.M. Salter, and H.S. Lee. 2015. Role of the sympathetic nervous system in carbon tetrachloride-induced hepatotoxicity and systemic inflammation. PLoS ONE 10: 18.","journal-title":"PLoS ONE"},{"key":"1854_CR43","first-page":"11","volume":"2016","author":"JC Lin","year":"2016","unstructured":"Lin, J.C., Y.J. Peng, S.Y. Wang, M.J. Lai, T.H. Young, D.M. Salter, et al. 2016. Sympathetic nervous system control of carbon tetrachloride-induced oxidative stress in liver through alpha-adrenergic signaling. Oxidative Medicine and Cellular Longevity 2016: 11.","journal-title":"Oxidative Medicine and Cellular Longevity"},{"key":"1854_CR44","doi-asserted-by":"crossref","first-page":"G811","DOI":"10.1152\/ajpgi.00047.2019","volume":"317","author":"SB Lee","year":"2019","unstructured":"Lee, S.B., H.G. Kim, J.S. Lee, W.Y. Kim, M.M. Lee, Y.H. Kim, et al. 2019. Intermittent restraint-induced sympathetic activation attenuates hepatic steatosis and inflammation in a high-fat diet-fed mouse model. American Journal of Physiology. Gastrointestinal and Liver Physiology 317: G811\u2013G823.","journal-title":"American Journal of Physiology. Gastrointestinal and Liver Physiology"},{"key":"1854_CR45","doi-asserted-by":"crossref","unstructured":"Nakade, Y., M. Yoneda, K. Nakamura, I. Makino, A. Terano. 2002. Involvement of endogenous CRF in carbon tetrachlorideinduced acute liver injury in rats. The\u00a0American Journal of Physiology-Regulatory,\u00a0Integrative\u00a0and Comparative Physiology\u00a0282:1782\u20138.","DOI":"10.1152\/ajpregu.00514.2001"},{"key":"1854_CR46","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1124\/jpet.116.233841","volume":"359","author":"J Zhang","year":"2016","unstructured":"Zhang, J., L. Zhang, X. Sun, Y. Yang, L. Kong, C. Lu, et al. 2016. Acetylcholinesterase Inhibitors for Alzheimer\u2019s disease treatment ameliorate acetaminophen-induced liver injury in mice via central cholinergic system regulation. Journal of Pharmacology and Experimental Therapeutics 359: 374\u2013382.","journal-title":"Journal of Pharmacology and Experimental Therapeutics"},{"key":"1854_CR47","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.1007\/s00268-005-0073-2","volume":"29","author":"SB Akinci","year":"2005","unstructured":"Akinci, S.B., N. Ulu, O.Z. Yondem, P. Firat, M.O. Guc, M. Kanbak, et al. 2005. Effect of neostigmine on organ injury in murine endotoxemia: Missing facts about the cholinergic antiinflammatory pathway. World Journal of Surgery 29: 1483\u20131489.","journal-title":"World Journal of Surgery"},{"key":"1854_CR48","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1471-230X-14-148","volume":"14","author":"N Steinebrunner","year":"2014","unstructured":"Steinebrunner, N., C. Mogler, S. Vittas, B. Hoyler, C. Sandig, W. Stremmel, et al. 2014. Pharmacologic cholinesterase inhibition improves survival in acetaminophen-induced acute liver failure in the mouse. BMC Gastroenterology 14: 148\u2013156.","journal-title":"BMC Gastroenterology"},{"key":"1854_CR49","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1166\/jnn.2018.13933","volume":"18","author":"OME Abdel-Salam","year":"2018","unstructured":"Abdel-Salam, O.M.E., E.R. Youness, R.S.E. Esmail, N.A. Mohammed, Y.A. Khadrawy, A.A. Sleem, et al. 2018. Protection by neostigmine and atropine against brain and liver injury induced by acute malathion exposure. Journal of Nanoscience and Nanotechnology 18: 510\u2013521.","journal-title":"Journal of Nanoscience and Nanotechnology"},{"key":"1854_CR50","doi-asserted-by":"crossref","first-page":"2919","DOI":"10.1002\/art.23807","volume":"58","author":"JM Waldburger","year":"2008","unstructured":"Waldburger, J.M., D.L. Boyle, M. Edgar, L.S. Sorkin, Y.A. Levine, V.A. Pavlov, et al. 2008. Spinal p38 MAP kinase regulates peripheral cholinergic outflow. Arthritis and Rheumatism 58: 2919\u20132921.","journal-title":"Arthritis and Rheumatism"},{"key":"1854_CR51","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1074\/jbc.RA118.003443","volume":"293","author":"MC Maldifassi","year":"2018","unstructured":"Maldifassi, M.C., C. Martin-Sanchez, G. Atienza, J.L. Cedillo, F. Arnalich, A. Bordas, et al. 2018. Interaction of the alpha7-nicotinic subunit with its human-specific duplicated dupalpha7 isoform in mammalian cells: Relevance in human inflammatory responses. Journal of Biological Chemistry 293: 27.","journal-title":"Journal of Biological Chemistry"},{"key":"1854_CR52","volume":"321","author":"MH Hur","year":"2023","unstructured":"Hur, M.H., W. Song, D.H. Cheon, Y. Chang, Y.Y. Cho, Y.B. Lee, et al. 2023. Chemogenetic stimulation of the parasympathetic nervous system lowers hepatic lipid accumulation and inflammation in a nonalcoholic steatohepatitis mouse model. Life Sciences 321: 121533.","journal-title":"Life Sciences"},{"key":"1854_CR53","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1007\/s11255-014-0766-2","volume":"46","author":"R Ologunde","year":"2014","unstructured":"Ologunde, R., H. Zhao, K. Lu, and D. Ma. 2014. Organ cross talk and remote organ damage following acute kidney injury. International Urology and Nephrology 46: 2337\u20132345.","journal-title":"International Urology and Nephrology"},{"key":"1854_CR54","first-page":"9","volume":"117","author":"Y Lai","year":"2019","unstructured":"Lai, Y., J. Deng, M. Wang, M. Wang, L. Zhou, G. Meng, et al. 2019. Vagus nerve stimulation protects against acute liver injury induced by renal ischemia reperfusion via antioxidant stress and anti-inflammation. Biomedicine & Pharmacotherapy 117: 9.","journal-title":"Biomedicine & Pharmacotherapy"},{"key":"1854_CR55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jcp.27682","volume":"234","author":"J Sha","year":"2019","unstructured":"Sha, J., X. Feng, Y. Chen, H. Zhang, B. Li, X. Hu, et al. 2019. Dexmedetomidine improves acute stress-induced liver injury in rats by regulating MKP-1, inhibiting NF-kappaB pathway and cell apoptosis. Journal of Cellular Physiology 234: 1\u201311.","journal-title":"Journal of Cellular Physiology"},{"key":"1854_CR56","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/s41420-023-01400-6","volume":"9","author":"B Mukhopadhyay","year":"2023","unstructured":"Mukhopadhyay, B., K. Holovac, K. Schuebel, P. Mukhopadhyay, R. Cinar, S. Iyer, et al. 2023. The endocannabinoid system promotes hepatocyte progenitor cell proliferation and maturation by modulating cellular energetics. Cell Death Discov. 9: 104.","journal-title":"Cell Death Discov."},{"key":"1854_CR57","doi-asserted-by":"crossref","first-page":"874","DOI":"10.1002\/ar.a.20081","volume":"280","author":"JA Oben","year":"2004","unstructured":"Oben, J.A., and A.M. Diehl. 2004. Sympathetic nervous system regulation of liver repair. The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology 280: 874\u2013883.","journal-title":"The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology"},{"key":"1854_CR58","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1053\/jhep.2003.50371","volume":"38","author":"JA Oben","year":"2003","unstructured":"Oben, J.A., T. Roskams, S. Yang, H. Lin, N. Sinelli, Z. Li, et al. 2003. Sympathetic nervous system inhibition increases hepatic progenitors and reduces liver injury. Hepatology 38: 664\u2013673.","journal-title":"Hepatology"},{"key":"1854_CR59","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1159\/000065594","volume":"66","author":"T Kiba","year":"2002","unstructured":"Kiba, T. 2002. The role of the autonomic nervous system in liver regeneration and apoptosis\u2013recent developments. Digestion 66: 79\u201388.","journal-title":"Digestion"},{"key":"1854_CR60","doi-asserted-by":"crossref","unstructured":"Kamimura, K., R. Inoue, T. Nagoya, N. Sakai, R. Goto, M. Ko, Y. Niwa, and S. Terai. 2018. Autonomic nervous system network and liver regeneration. World Journal of Gastroenterology 24:1583\u2013678.","DOI":"10.3748\/wjg.v24.i15.1616"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-023-01854-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10753-023-01854-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-023-01854-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,24]],"date-time":"2024-10-24T23:03:01Z","timestamp":1729810981000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10753-023-01854-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,25]]},"references-count":60,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["1854"],"URL":"https:\/\/doi.org\/10.1007\/s10753-023-01854-x","relation":{},"ISSN":["0360-3997","1573-2576"],"issn-type":[{"value":"0360-3997","type":"print"},{"value":"1573-2576","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,25]]},"assertion":[{"value":"4 March 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 May 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}