{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:50:14Z","timestamp":1761864614614,"version":"build-2065373602"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T00:00:00Z","timestamp":1724803200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammation"],"DOI":"10.1007\/s10753-024-02131-1","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T07:02:29Z","timestamp":1724828549000},"page":"1003-1014","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Oral Administration of Piperine Ameliorates Experimental Autoimmune Uveitis"],"prefix":"10.1007","volume":"48","author":[{"given":"Alireza","family":"Ghavami","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2579-6618","authenticated-orcid":false,"given":"Seyyed Meysam","family":"Abtahi Froushani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aliasghar","family":"Tehrani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"issue":"4","key":"2131_CR1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062071","volume":"8","author":"CB Fang","year":"2013","unstructured":"Fang, C.B., D.X. Zhou, S.X. Zhan, Y. He, Z. Lin, C. Huang, and J. Li. 2013. Amelioration of experimental autoimmune uveitis by leflunomide in Lewis rats. PLoS ONE 8 (4): e62071. https:\/\/doi.org\/10.1371\/journal.pone.0062071.","journal-title":"PLoS ONE"},{"key":"2131_CR2","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.756423","volume":"12","author":"N Chen","year":"2021","unstructured":"Chen, N., S. Chen, Z. Zhang, X. Cui, L. Wu, K. Guo, et al. 2021. Overexpressing Kallistatin aggravates experimental autoimmune uveitis through Promoting Th17 differentiation. Frontiers in Immunology 12: 756423. https:\/\/doi.org\/10.3389\/fimmu.2021.756423.","journal-title":"Frontiers in Immunology"},{"key":"2131_CR3","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.744396","volume":"12","author":"K Glover","year":"2021","unstructured":"Glover, K., D. Mishra, and T.R.R. Singh. 2021. Epidemiology of ocular manifestations in autoimmune disease. Frontiers in Immunology 12: 744396. https:\/\/doi.org\/10.3389\/fimmu.2021.744396.","journal-title":"Frontiers in Immunology"},{"issue":"7","key":"2131_CR4","first-page":"475","volume":"21","author":"L Gamalero","year":"2019","unstructured":"Gamalero, L., G. Simonini, G. Ferrara, S. Polizzi, T. Giani, and R. Cimaz. 2019. Evidence-based treatment for uveitis. The Israel Medical Association Journal 21 (7): 475\u2013479.","journal-title":"The Israel Medical Association Journal"},{"key":"2131_CR5","doi-asserted-by":"publisher","first-page":"1773","DOI":"10.3389\/fimmu.2018.01773","volume":"9","author":"M Kasper","year":"2018","unstructured":"Kasper, M., K. Walscheid, B. Laffer, D. Bauer, M. Busch, L. Wildsch\u00fctz, et al. 2018. The phenotype of monocytes in anterior uveitis depends on the HLA-B27 status. Frontiers in Immunology 9: 1773. https:\/\/doi.org\/10.3389\/fimmu.2018.01773.","journal-title":"Frontiers in Immunology"},{"key":"2131_CR6","doi-asserted-by":"publisher","unstructured":"Gilger, B. C. 2022. Developing advanced therapeutics through the study of naturally occurring immune-mediated ocular disease in domestic animals. American Journal of Veterinary Research 83(11): najvr.22.08.0145.\u00a0https:\/\/doi.org\/10.2460\/ajvr.22.08.0145.","DOI":"10.2460\/ajvr.22.08.0145"},{"issue":"3\u20134","key":"2131_CR7","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1007\/s11259-016-9659-4","volume":"40","author":"GP Simeonova","year":"2016","unstructured":"Simeonova, G.P., S.Z. Krastev, and R.S. Simeonov. 2016. Immunological and pathological investigations in equine experimental uveitis. Veterinary Research Communications 40 (3\u20134): 107\u2013115. https:\/\/doi.org\/10.1007\/s11259-016-9659-4.","journal-title":"Veterinary Research Communications"},{"key":"2131_CR8","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.preteyeres.2018.02.003","volume":"65","author":"M Diedrichs-M\u00f6hring","year":"2018","unstructured":"Diedrichs-M\u00f6hring, M., U. Kaufmann, and G. Wildner. 2018. The immunopathogenesis of chronic and relapsing autoimmune uveitis - Lessons from experimental rat models. Progress in Retinal and Eye Research 65: 107\u2013126. https:\/\/doi.org\/10.1016\/j.preteyeres.2018.02.003.","journal-title":"Progress in Retinal and Eye Research"},{"issue":"3","key":"2131_CR9","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1007\/s10787-022-00957-5","volume":"30","author":"S Etemadi","year":"2022","unstructured":"Etemadi, S., S.M. Abtahi Froushani, S.M. Hashemi Asl, and A. Mahmoudian. 2022. Combined atorvastatin and pentoxifylline in ameliorating inflammation induced by complete Freund\u2019s adjuvant. Inflammopharmacology 30 (3): 935\u2013944. https:\/\/doi.org\/10.1007\/s10787-022-00957-5.","journal-title":"Inflammopharmacology"},{"key":"2131_CR10","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.117037","volume":"239","author":"S Golbahari","year":"2019","unstructured":"Golbahari, S., and S.M. Abtahi Froushani. 2019. Synergistic benefits of Nicotine and Thymol in alleviating experimental rheumatoid arthritis. Life Sciences 239: 117037. https:\/\/doi.org\/10.1016\/j.lfs.2019.117037.","journal-title":"Life Sciences"},{"issue":"3","key":"2131_CR11","doi-asserted-by":"publisher","first-page":"211","DOI":"10.4103\/0301-4738.156914","volume":"63","author":"S Bansal","year":"2015","unstructured":"Bansal, S., V.A. Barathi, D. Iwata, and R. Agrawal. 2015. Experimental autoimmune uveitis and other animal models of uveitis: An update. Indian Journal of Ophthalmology 63 (3): 211\u2013218. https:\/\/doi.org\/10.4103\/0301-4738.156914.","journal-title":"Indian Journal of Ophthalmology"},{"key":"2131_CR12","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/978-1-60761-720-4_22","volume":"900","author":"RK Agarwal","year":"2012","unstructured":"Agarwal, R.K., P.B. Silver, and R.R. Caspi. 2012. Rodent models of experimental autoimmune uveitis. Methods in Molecular Biology 900: 443\u2013469. https:\/\/doi.org\/10.1007\/978-1-60761-720-4_22.","journal-title":"Methods in Molecular Biology"},{"issue":"11","key":"2131_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4103\/0973-7847.95849","volume":"6","author":"BB Petrovska","year":"2012","unstructured":"Petrovska, B.B. 2012. Historical review of medicinal plants\u2019 usage. Pharmacognosy Reviews 6 (11): 1\u20135. https:\/\/doi.org\/10.4103\/0973-7847.95849.","journal-title":"Pharmacognosy Reviews"},{"issue":"2","key":"2131_CR14","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1002\/ptr.6855","volume":"35","author":"IU Haq","year":"2021","unstructured":"Haq, I.U., M. Imran, M. Nadeem, T. Tufail, T.A. Gondal, and M.S. Mubarak. 2021. Piperine: A review of its biological effects. Phytotherapy Research 35 (2): 680\u2013700. https:\/\/doi.org\/10.1002\/ptr.6855.","journal-title":"Phytotherapy Research"},{"issue":"11","key":"2131_CR15","doi-asserted-by":"publisher","first-page":"1227","DOI":"10.22038\/ijbms.2017.9487","volume":"20","author":"SA Sudjarwo","year":"2017","unstructured":"Sudjarwo, S.A., K. Eraiko, G.W. Sudjarwo, and Koerniasari. 2017. Protective effects of piperine on lead acetate induced-nephrotoxicity in rats. Iranian Journal of Basic Medical Sciences 20 (11): 1227\u201331. https:\/\/doi.org\/10.22038\/ijbms.2017.9487.","journal-title":"Iranian Journal of Basic Medical Sciences"},{"issue":"2","key":"2131_CR16","doi-asserted-by":"publisher","first-page":"185","DOI":"10.2478\/acph-2021-0015","volume":"71","author":"CR Quijia","year":"2021","unstructured":"Quijia, C.R., V.H. Araujo, and M. Chorilli. 2021. Piperine: Chemical, biological and nanotechnological applications. Acta Pharmaceutica 71 (2): 185\u2013213. https:\/\/doi.org\/10.2478\/acph-2021-0015.","journal-title":"Acta Pharmaceutica"},{"key":"2131_CR17","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.toxlet.2015.11.025","volume":"242","author":"G Rodgers","year":"2016","unstructured":"Rodgers, G., C.D. Doucette, D.A. Soutar, R.S. Liwski, and D.W. Hoskin. 2016. Piperine impairs the migration and T cell-activating function of dendritic cells. Toxicology Letters 242: 23\u201333. https:\/\/doi.org\/10.1016\/j.toxlet.2015.11.025.","journal-title":"Toxicology Letters"},{"issue":"1","key":"2131_CR18","doi-asserted-by":"publisher","first-page":"617","DOI":"10.4238\/2012.March.14.5","volume":"11","author":"S Chuchawankul","year":"2012","unstructured":"Chuchawankul, S., N. Khorana, and Y. Poovorawan. 2012. Piperine inhibits cytokine production by human peripheral blood mononuclear cells. Genetics and Molecular Research 11 (1): 617\u2013627. https:\/\/doi.org\/10.4238\/2012.March.14.5.","journal-title":"Genetics and Molecular Research"},{"issue":"11","key":"2131_CR19","doi-asserted-by":"publisher","first-page":"5473","DOI":"10.1007\/s12035-021-02497-5","volume":"58","author":"R Nasrnezhad","year":"2021","unstructured":"Nasrnezhad, R., S. Halalkhor, F. Sadeghi, and F. Pourabdolhossein. 2021. Piperine improves experimental autoimmune encephalomyelitis (EAE) in Lewis rats through its neuroprotective, anti-inflammatory, and antioxidant effects. Molecular Neurobiology 58 (11): 5473\u20135493. https:\/\/doi.org\/10.1007\/s12035-021-02497-5.","journal-title":"Molecular Neurobiology"},{"key":"2131_CR20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2023.104752","volume":"391\u2013392","author":"QN Baito","year":"2023","unstructured":"Baito, Q.N., H.M. Jaafar, and T.A.M. Mohammad. 2023. Piperine suppresses inflammatory fibroblast-like synoviocytes derived from rheumatoid arthritis patients Via NF-\u03baB inhibition. Cellular Immunology 391\u2013392: 104752. https:\/\/doi.org\/10.1016\/j.cellimm.2023.104752.","journal-title":"Cellular Immunology"},{"key":"2131_CR21","doi-asserted-by":"publisher","first-page":"15.6.1","DOI":"10.1002\/0471142735.im1506s53","volume":"15","author":"RR Caspi","year":"2003","unstructured":"Caspi, R.R. 2003. Experimental autoimmune uveoretinitis in the rat and mouse. Curr Protoc Immunol 15: 15.6.1\u20136.20. https:\/\/doi.org\/10.1002\/0471142735.im1506s53.","journal-title":"Curr Protoc Immunol"},{"issue":"4","key":"2131_CR22","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1016\/j.jfo.2011.05.003","volume":"35","author":"A Arroul-Lammali","year":"2012","unstructured":"Arroul-Lammali, A., Z. Djeraba, M. Belkhelfa, H. Belguendouz, D. Hartani, O.S. Lahlou-Boukoffa, and C. Touil-Boukoffa. 2012. Early involvement of nitric oxide in mechanisms of pathogenesis of experimental autoimmune uveitis induced by interphotoreceptor retinoid-binding protein (IRBP). Journal Francais d\u2019Ophtalmologie 35 (4): 251\u2013259. https:\/\/doi.org\/10.1016\/j.jfo.2011.05.003.","journal-title":"Journal Francais d'Ophtalmologie"},{"issue":"3\u20134","key":"2131_CR23","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/s0891-5849(99)00067-2","volume":"27","author":"F Bosch-Morell","year":"1999","unstructured":"Bosch-Morell, F., J. Rom\u00e1, F.J. Puertas, N. Mar\u00edn, M. D\u00edaz-Llopis, and F.J. Romero. 1999. Efficacy of the antioxidant ebselen in experimental uveitis. Free Radical Biology & Medicine 27 (3\u20134): 388\u2013391. https:\/\/doi.org\/10.1016\/s0891-5849(99)00067-2.","journal-title":"Free Radical Biology & Medicine"},{"issue":"3","key":"2131_CR24","doi-asserted-by":"publisher","first-page":"901","DOI":"10.3892\/etm.2014.2146","volume":"9","author":"K Asghar","year":"2015","unstructured":"Asghar, K., M.T. Ashiq, B. Zulfiqar, A. Mahroo, K. Nasir, and S. Murad. 2015. Indoleamine 2,3-dioxygenase expression and activity in patients with hepatitis C virus-induced liver cirrhosis. Experimental and Therapeutic Medicine 9 (3): 901\u2013904. https:\/\/doi.org\/10.3892\/etm.2014.2146.","journal-title":"Experimental and Therapeutic Medicine"},{"issue":"2","key":"2131_CR25","doi-asserted-by":"publisher","first-page":"504","DOI":"10.1016\/j.etap.2014.12.021","volume":"39","author":"A Kumar","year":"2015","unstructured":"Kumar, A., D. Sasmal, and N. Sharma. 2015. Immunomodulatory role of piperine in deltamethrin induced thymic apoptosis and altered immune functions. Environmental Toxicology and Pharmacology. 39 (2): 504\u2013514. https:\/\/doi.org\/10.1016\/j.etap.2014.12.021.","journal-title":"Environmental Toxicology and Pharmacology."},{"key":"2131_CR26","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1016\/j.biopha.2017.01.002","volume":"87","author":"V Dhivya","year":"2017","unstructured":"Dhivya, V., L.B. Priya, H.T. Chirayil, S. Sathiskumar, C.Y. Huang, and V.V. Padma. 2017. Piperine modulates isoproterenol induced myocardial ischemia through antioxidant and anti-dyslipidemic effect in male Wistar rats. Biomedicine & Pharmacotherapy 87: 705\u2013713. https:\/\/doi.org\/10.1016\/j.biopha.2017.01.002.","journal-title":"Biomedicine & Pharmacotherapy"},{"issue":"9\u201310","key":"2131_CR27","first-page":"453","volume":"57","author":"S Gawe\u0142","year":"2004","unstructured":"Gawe\u0142, S., M. Wardas, E. Niedworok, and P. Wardas. 2004. Malondialdehyde (MDA) as a lipid peroxidation marker. Wiadomosci Lekarskie 57 (9\u201310): 453\u2013455.","journal-title":"Wiadomosci Lekarskie"},{"issue":"3","key":"2131_CR28","doi-asserted-by":"publisher","first-page":"905","DOI":"10.1016\/s0002-9440(10)64913-9","volume":"160","author":"J Liversidge","year":"2002","unstructured":"Liversidge, J., A. Dick, and S. Gordon. 2002. Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas\/Fas-ligand interactions in experimental autoimmune uveitis. American Journal of Pathology 160 (3): 905\u2013916. https:\/\/doi.org\/10.1016\/s0002-9440(10)64913-9.","journal-title":"American Journal of Pathology"},{"key":"2131_CR29","doi-asserted-by":"publisher","first-page":"827407","DOI":"10.3389\/fvets.2022.827407","volume":"9","author":"HI Ahmad","year":"2022","unstructured":"Ahmad, H.I., A. Jabbar, N. Mushtaq, Z. Javed, M.U. Hayyat, J. Bashir, et al. 2022. Immune tolerance vs. immune resistance: The interaction between host and pathogens in infectious diseases. Frontiers in Veterinary Science 9: 827407. https:\/\/doi.org\/10.3389\/fvets.2022.827407.","journal-title":"Frontiers in Veterinary Science"},{"issue":"3","key":"2131_CR30","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/j.jaci.2014.11.001","volume":"135","author":"F Annunziato","year":"2015","unstructured":"Annunziato, F., C. Romagnani, and S. Romagnani. 2015. The 3 major types of innate and adaptive cell-mediated effector immunity. The Journal of Allergy and Clinical Immunology 135 (3): 626\u2013635. https:\/\/doi.org\/10.1016\/j.jaci.2014.11.001.","journal-title":"The Journal of Allergy and Clinical Immunology"},{"issue":"2","key":"2131_CR31","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1128\/cmr.00084-18","volume":"32","author":"P Zimmermann","year":"2019","unstructured":"Zimmermann, P., and N. Curtis. 2019. Factors That Influence the Immune Response to Vaccination. Clinical Microbiology Reviews 32 (2): 10. https:\/\/doi.org\/10.1128\/cmr.00084-18.","journal-title":"Clinical Microbiology Reviews"},{"issue":"14","key":"2131_CR32","doi-asserted-by":"publisher","first-page":"7517","DOI":"10.3390\/ijms22147517","volume":"22","author":"S Wu","year":"2021","unstructured":"Wu, S., R. Ma, Y. Zhong, Z. Chen, H. Zhou, M. Zhou, et al. 2021. Deficiency of IL-27 signaling exacerbates experimental autoimmune Uveitis with Elevated Uveitogenic Th1 and Th17 Responses. International Journal of Molecular Sciences 22 (14): 7517. https:\/\/doi.org\/10.3390\/ijms22147517.","journal-title":"International Journal of Molecular Sciences"},{"issue":"10","key":"2131_CR33","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.1084\/jem.20141678","volume":"212","author":"WP Chong","year":"2015","unstructured":"Chong, W.P., N. van Panhuys, J. Chen, P.B. Silver, Y. Jittayasothorn, M.J. Mattapallil, et al. 2015. NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-\u03b3-IL-27 axis. Journal of Experimental Medicine 212 (10): 1739\u20131752. https:\/\/doi.org\/10.1084\/jem.20141678.","journal-title":"Journal of Experimental Medicine"},{"issue":"1","key":"2131_CR34","doi-asserted-by":"publisher","first-page":"54","DOI":"10.3109\/08820139.2013.825269","volume":"43","author":"SM Abtahi Froushani","year":"2014","unstructured":"Abtahi Froushani, S.M., N. Delirezh, R. Hobbenaghi, and G. Mosayebi. 2014. Synergistic effects of atorvastatin and all-trans retinoic acid in ameliorating animal model of multiple sclerosis. Immunological Investigations 43 (1): 54\u201368. https:\/\/doi.org\/10.3109\/08820139.2013.825269.","journal-title":"Immunological Investigations"},{"issue":"5","key":"2131_CR35","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1250","volume":"13","author":"X Liu","year":"2023","unstructured":"Liu, X., Y. Su, Z. Huang, J. Lv, C. Gu, Z. Li, et al. 2023. Sleep loss potentiates Th17-cell pathogenicity and promotes autoimmune uveitis. Clinical and Translational Medicine 13 (5): e1250. https:\/\/doi.org\/10.1002\/ctm2.1250.","journal-title":"Clinical and Translational Medicine"},{"key":"2131_CR36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2024.03.013","author":"C Gu","year":"2024","unstructured":"Gu, C., Y. Liu, J. Lv, C. Zhang, Z. Huang, Q. Jiang, et al. 2024. Kurarinone regulates Th17\/Treg balance and ameliorates autoimmune uveitis via Rac1 inhibition. Journal of Advanced Research. https:\/\/doi.org\/10.1016\/j.jare.2024.03.013.","journal-title":"Journal of Advanced Research"},{"issue":"5","key":"2131_CR37","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1007\/s00417-019-04255-9","volume":"257","author":"B Matta","year":"2019","unstructured":"Matta, B., P.S. Bora, A.J. Neuhouser, and N.S. Bora. 2019. Inhibitory role of transforming growth factor \u03b22 in experimental autoimmune anterior uveitis. Graefes Archive for Clinical and Experimental Ophthalmology 257 (5): 953\u2013960. https:\/\/doi.org\/10.1007\/s00417-019-04255-9.","journal-title":"Graefes Archive for Clinical and Experimental Ophthalmology"},{"issue":"11","key":"2131_CR38","doi-asserted-by":"publisher","first-page":"2577","DOI":"10.1002\/jcb.25202","volume":"116","author":"CD Doucette","year":"2015","unstructured":"Doucette, C.D., G. Rodgers, R.S. Liwski, and D.W. Hoskin. 2015. Piperine from black pepper inhibits activation-induced proliferation and effector function of T lymphocytes. Journal of Cellular Biochemistry 116 (11): 2577\u20132588. https:\/\/doi.org\/10.1002\/jcb.25202.","journal-title":"Journal of Cellular Biochemistry"},{"issue":"3","key":"2131_CR39","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3390\/vaccines3030703","volume":"3","author":"JC Mbongue","year":"2015","unstructured":"Mbongue, J.C., D.A. Nicholas, T.W. Torrez, N.S. Kim, A.F. Firek, and W.H. Langridge. 2015. The Role of Indoleamine 2, 3-Dioxygenase in immune suppression and autoimmunity. Vaccines (Basel). 3 (3): 703\u2013729. https:\/\/doi.org\/10.3390\/vaccines3030703.","journal-title":"Vaccines (Basel)."},{"issue":"12","key":"2131_CR40","doi-asserted-by":"publisher","first-page":"2959","DOI":"10.1007\/s11064-020-03144-6","volume":"45","author":"MS Zarzecki","year":"2020","unstructured":"Zarzecki, M.S., L. Cattelan Souza, R. Giacomeli, M.R.P. Silva, M. Prigol, S.P. Boeira, and C.R. Jesse. 2020. Involvement of Indoleamine-2,3-Dioxygenase and kynurenine pathway in experimental autoimmune encephalomyelitis in mice. Neurochemical Research 45 (12): 2959\u20132977. https:\/\/doi.org\/10.1007\/s11064-020-03144-6.","journal-title":"Neurochemical Research"},{"issue":"7","key":"2131_CR41","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1007\/s00262-014-1549-4","volume":"63","author":"GC Prendergast","year":"2014","unstructured":"Prendergast, G.C., C. Smith, S. Thomas, L. Mandik-Nayak, L. Laury-Kleintop, R. Metz, and A.J. Muller. 2014. Indoleamine 2,3-dioxygenase pathways of pathogenic inflammation and immune escape in cancer. Cancer Immunology, Immunotherapy 63 (7): 721\u2013735. https:\/\/doi.org\/10.1007\/s00262-014-1549-4.","journal-title":"Cancer Immunology, Immunotherapy"},{"issue":"9","key":"2131_CR42","doi-asserted-by":"publisher","first-page":"10132","DOI":"10.3390\/molecules180910132","volume":"18","author":"MG Iachininoto","year":"2013","unstructured":"Iachininoto, M.G., E.R. Nuzzolo, G. Bonanno, A. Mariotti, A. Procoli, F. Locatelli, et al. 2013. Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells. Molecules 18 (9): 10132\u201310145. https:\/\/doi.org\/10.3390\/molecules180910132.","journal-title":"Molecules"},{"issue":"7","key":"2131_CR43","doi-asserted-by":"publisher","first-page":"2342","DOI":"10.1016\/j.fct.2012.04.024","volume":"50","author":"HG Kim","year":"2012","unstructured":"Kim, H.G., E.H. Han, W.S. Jang, J.H. Choi, T. Khanal, B.H. Park, et al. 2012. Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-\u03baB, C\/EBP and AP-1 signaling pathways in murine macrophages. Food and Chemical Toxicology 50 (7): 2342\u20132348. https:\/\/doi.org\/10.1016\/j.fct.2012.04.024.","journal-title":"Food and Chemical Toxicology"}],"container-title":["Inflammation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-024-02131-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10753-024-02131-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10753-024-02131-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,8]],"date-time":"2025-07-08T14:05:05Z","timestamp":1751983505000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10753-024-02131-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,28]]},"references-count":43,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2025,6]]}},"alternative-id":["2131"],"URL":"https:\/\/doi.org\/10.1007\/s10753-024-02131-1","relation":{},"ISSN":["1573-2576"],"issn-type":[{"type":"electronic","value":"1573-2576"}],"subject":[],"published":{"date-parts":[[2024,8,28]]},"assertion":[{"value":"13 June 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2024","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 August 2024","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2024","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All procedures concerning animal experiments were approved by our University Ethics.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval"}},{"value":"Written informed consent was obtained from the participants\u2019 legal guardians.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Participate"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}