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The use of human blood samples was approved by the Medical Institutional Ethics Committee of Qilu Hospital, Shandong University, China (Approval No. KYLL-2020(KS)-537), and informed consent was obtained from all donors.All animal procedures adhered to protocols approved by the Animal Care and Use Committee of Shandong University (Approval No. DWLL-2021-143).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Clinical trial number"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"149"}}