{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:15:15Z","timestamp":1792635315082,"version":"4.5.0"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T00:00:00Z","timestamp":1476403200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1007\/s10787-016-0290-3","type":"journal-article","created":{"date-parts":[[2016,10,14]],"date-time":"2016-10-14T02:18:57Z","timestamp":1476411537000},"page":"363-375","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":38,"title":["Amelioration of oxidative and inflammatory changes by Swertia chirayita leaves in experimental arthritis"],"prefix":"10.1007","volume":"24","author":[{"given":"Harsha","family":"Lad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Bhatnagar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,10,14]]},"reference":[{"key":"290_CR1","first-page":"21","volume":"32","author":"S Banerjee","year":"2000","unstructured":"Banerjee S, Sur TK, Mandal S, Das PK, Sikdar S (2000) Assessment of anti-inflammatory effects of Swertia chirata in acute and chronic experimental models in male albino rats. Ind J Pharmacol 32:21\u201324","journal-title":"Ind J Pharmacol"},{"key":"290_CR2","doi-asserted-by":"crossref","first-page":"2784","DOI":"10.1073\/pnas.95.6.2784","volume":"95","author":"BS Berlett","year":"1998","unstructured":"Berlett BS, Levine RL, Stadtman ER (1998) Carbon dioxide stimulates peroxynitrite-mediated nitration of tyrosine residues and inhibits oxidation of methionine residues of glutamine synthetase: both modifications mimic effects of adenylylation. Proc Nat Acad Sci (USA) 95:2784\u20132789","journal-title":"Proc Nat Acad Sci (USA)"},{"key":"290_CR3","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1139\/y93-111","volume":"71","author":"TM Bray","year":"1993","unstructured":"Bray TM, Taylor CG (1993) Tissue glutathione, nutrition and oxidative stress. Can J Physiol Pharmacol 71:746\u2013751","journal-title":"Can J Physiol Pharmacol"},{"key":"290_CR4","doi-asserted-by":"crossref","first-page":"2157","DOI":"10.1016\/j.lfs.2003.09.047","volume":"74","author":"Y Cai","year":"2004","unstructured":"Cai Y, Luo Q, Sun M, Corke H (2004) Antioxidant activity and phenolic compounds of 112 traditional Chinese medicinal plants associated with anticancer. Life Sci 74:2157\u20132184","journal-title":"Life Sci"},{"key":"290_CR5","first-page":"93","volume":"99","author":"SM Caparroz-Assef","year":"1998","unstructured":"Caparroz-Assef SM, Bersani-Amado CA, Nascimento EA, Kelmer-Bracht AM, Ishii-Iwamoto EL (1998) Effects of the nonsteroidal anti-inflammatory drug nimesulide on energy metabolism in livers from adjuvant-induced arthritic rats. Res Commun Mol Pathol Pharmacol 99:93\u2013116","journal-title":"Res Commun Mol Pathol Pharmacol"},{"key":"290_CR6","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S1357-4310(00)01757-3","volume":"6","author":"NL Carteron","year":"2000","unstructured":"Carteron NL (2000) Cytokines in rheumatoid arthritis: trials and tribulations. Mol Med Today 6:315\u2013323","journal-title":"Mol Med Today"},{"key":"290_CR7","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1600-051X.1997.tb00760.x","volume":"24","author":"IL Chapple","year":"1997","unstructured":"Chapple IL (1997) Reactive oxygen species and antioxidants in inflammatory diseases. J Clin Periodontol 24:287\u2013296","journal-title":"J Clin Periodontol"},{"key":"290_CR8","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/(SICI)1099-1573(199703)11:2<152::AID-PTR45>3.0.CO;2-L","volume":"11","author":"CT Chou","year":"1997","unstructured":"Chou CT (1997) The anti-inflammatory effect of Tripterygium wilfordii Hook F on adjuvant-induced paw edema in rats and inflammatory mediators release. Phytother Res 11:152\u2013154","journal-title":"Phytother Res"},{"key":"290_CR9","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.freeradbiomed.2012.12.003","volume":"58","author":"JF Comar","year":"2013","unstructured":"Comar JF, Nakanishi AB, de Oliveira AL, Wendt MMN, Amado CAB, Iwamoto ELI, Peralta RM, Bracht AA (2013) Oxidative state of the liver of rats with adjuvant-induced arthritis. Free Radic Biol Med 58:144\u2013153","journal-title":"Free Radic Biol Med"},{"key":"290_CR10","first-page":"31","volume":"5","author":"SC Das","year":"2012","unstructured":"Das SC, Bhadra S, Roy S, Saha SK, Md Islam S, Bachar SC (2012) Analgesic and anti-inflammatory activities of ethanolic root extract of Swertia chirata (Gentianaceae). Jordan J Biol Sci 5:31\u201336","journal-title":"Jordan J Biol Sci"},{"key":"290_CR11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1152\/physrev.00018.2001","volume":"82","author":"W Droge","year":"2002","unstructured":"Droge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82:47\u201395","journal-title":"Physiol Rev"},{"key":"290_CR12","first-page":"317","volume":"4","author":"AK Dutta","year":"2012","unstructured":"Dutta AK, Gope PS, Makhnoon S, Md Rahman S, Siddiquee MA, Kabir Y (2012) Effect of Solvent extraction on Phenolic content, Antioxidant and \u03b1-Amylase Inhibition activities of Swertia chirata. Int J Drug Dev Res 4:317\u2013325","journal-title":"Int J Drug Dev Res"},{"key":"290_CR13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1186\/1472-6882-10-56","volume":"10","author":"S Ekambaram","year":"2010","unstructured":"Ekambaram S, Perumal SS, Subramanian V (2010) Evaluation of antiarthritic activity of Strychnos potatoum Linn seeds in Freund\u2019s adjuvant induced arthritic rat model. Complement Altern Med 10:56","journal-title":"Complement Altern Med"},{"key":"290_CR14","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0891-5849(91)90192-6","volume":"11","author":"H Esterbauer","year":"1991","unstructured":"Esterbauer H, Schaur RJ, Zollner H (1991) Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med 11:81\u2013128","journal-title":"Free Radic Biol Med"},{"key":"290_CR15","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1002\/(SICI)1099-0844(199912)17:4<271::AID-CBF839>3.0.CO;2-P","volume":"17","author":"Z Fedatto Jr","year":"1999","unstructured":"Fedatto Z Jr, Ishiii-Iwamoto EL, Amado CB, Vicentini G, D\u2019urso-Panerari A, Bracht A, Kelmer-Bracht AM (1999) Gluconeogenesis in the liver of arthritic rats. Cell Biochem Funct 17:271\u2013278","journal-title":"Cell Biochem Funct"},{"key":"290_CR16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1111\/j.1365-2249.2008.03634.x","volume":"152","author":"LI Filippin","year":"2008","unstructured":"Filippin LI, Vercelino R, Marroni NP, Xavier RM (2008) Redox signaling and the inflammatory response in rheumatoid arthritis. Clin Exp Immunol 152:415\u2013422","journal-title":"Clin Exp Immunol"},{"key":"290_CR17","doi-asserted-by":"crossref","first-page":"232","DOI":"10.3109\/s10165-005-0412-z","volume":"15","author":"DM Findlay","year":"2005","unstructured":"Findlay DM, Haynes DR (2005) Mechanisms of bone loss in rheumatoid arthritis. Mod Rheumatol 15:232\u2013240","journal-title":"Mod Rheumatol"},{"key":"290_CR18","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/10409239509083491","volume":"30","author":"ID Hayes","year":"1995","unstructured":"Hayes ID, Pulford DJ (1995) The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit Rev Biochem Mol Biol 30:445\u2013600","journal-title":"Crit Rev Biochem Mol Biol"},{"key":"290_CR19","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1186\/ar1447","volume":"6","author":"CA Hitchon","year":"2004","unstructured":"Hitchon CA, El-Gabalawy HS (2004) Oxidation in rheumatoid arthritis. Arthritis Res Ther 6:265\u2013278","journal-title":"Arthritis Res Ther"},{"key":"290_CR20","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1021\/jf030723c","volume":"53","author":"D Huang","year":"2005","unstructured":"Huang D, Ou B, Prior RL (2005) The chemistry behind antioxidant capacity assays. J Agric Food Chem 53:1841\u20131856","journal-title":"J Agric Food Chem"},{"key":"290_CR21","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1365-2249.1994.tb06574.x","volume":"97","author":"AC Issekutz","year":"1994","unstructured":"Issekutz AC, Meager A, Otternesst I, Issekutz TB (1994) The role of tumor necrosis factor-alpha and IL-1 in polymorphonuclear leucocyte and T lymphocyte recruitment to joint inflammation in adjuvant arthritis. Clin Exp Immunol 97:26\u201332","journal-title":"Clin Exp Immunol"},{"key":"290_CR22","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/(SICI)1099-1573(199902)13:1<24::AID-PTR378>3.0.CO;2-L","volume":"13","author":"M Karan","year":"1999","unstructured":"Karan M, Vashisht K, Handa SS (1999) Anti-hepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats. Phytother Res 13:24\u201330","journal-title":"Phytother Res"},{"key":"290_CR23","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/S0171-2985(83)80048-5","volume":"165","author":"Y Keisari","year":"1983","unstructured":"Keisari Y, Braun L, Flescher E (1983) The oxidative burst and related phenomena in mouse macrophages elicited by different sterile inflammatory stimuli. Immunobiology 165:78\u201389","journal-title":"Immunobiology"},{"key":"290_CR24","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/ar86","volume":"2","author":"RW Kinne","year":"2000","unstructured":"Kinne RW, Brauer R, Stuhlmuller B, Kinne EP, Burmester GR (2000) Macrophages in rheumatoid arthritis. Arthritis Res 2:189\u2013202","journal-title":"Arthritis Res"},{"key":"290_CR25","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s10067-006-0318-y","volume":"26","author":"T Kitamura","year":"2007","unstructured":"Kitamura T, Hashimoto J, Murase T, Tomita T, Hattori T, Yashikawa H, Sugamoto K (2007) Radiographic study of joint destruction patterns in rheumatoid elbow. Clin Rheumatol 26:515\u2013519","journal-title":"Clin Rheumatol"},{"key":"290_CR26","doi-asserted-by":"crossref","first-page":"5751","DOI":"10.1016\/S0021-9258(19)83842-5","volume":"257","author":"Y Kono","year":"1982","unstructured":"Kono Y, Fridovich I (1982) Superoxide radical inhibits catalase. J Biol Chem 257:5751\u20135754","journal-title":"J Biol Chem"},{"key":"290_CR27","first-page":"48","volume":"3","author":"RV Kumar","year":"2011","unstructured":"Kumar RV, Kumar S, Shashidhara S, Anitha S, Manjula M (2011) Comparison of the antioxidant capacity of an important hepatoprotective plants. Int J Pharm Sci Drug Res 3:48\u201351","journal-title":"Int J Pharm Sci Drug Res"},{"key":"290_CR28","first-page":"81","volume":"7","author":"H Lad","year":"2015","unstructured":"Lad H, Dixit D, Joshi A, Bhatnagar D (2015) Antioxidant and antiinflammatory effects of Vitex negundo on Freund\u2019s complete adjuvant induced arthritis. Int J Pharm Pharm Sci 7:81\u201385","journal-title":"Int J Pharm Pharm Sci"},{"key":"290_CR29","doi-asserted-by":"publisher","first-page":"217","DOI":"10.1007\/s13596-016-0234-x","volume":"16","author":"H Lad","year":"2016","unstructured":"Lad H, Joshi A, Dixit D, Sharma H, Bhatnagar D (2016) Antioxidant, genoprotective and immunomodulatory potential of Vitex negundo leaves in experimental arthritis. Orient Pharm Exp Med 16:217\u2013224. doi: 10.1007\/s13596-016-0234-x","journal-title":"Orient Pharm Exp Med"},{"key":"290_CR30","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/0076-6879(90)86141-H","volume":"186","author":"RL Levine","year":"1990","unstructured":"Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shaltiel S, Stadtman ER (1990) Determination of carbonyl content in modified proteins. Method Enzymol 186:464\u2013478","journal-title":"Method Enzymol"},{"key":"290_CR31","first-page":"316","volume":"34","author":"H Makinen","year":"2007","unstructured":"Makinen H, Kautiainen H, Hannonen P, Mottonen T, Leirisalo- Repo M, Laasonen L, Korpela M, Blafield H, Hakola M, Sokka T (2007) Sustained remission and reduced radiographic progression with combination disease modifying anti-rheumatic drugs in early rheumatoid arthritis. J Rheumatol 34:316\u2013321","journal-title":"J Rheumatol"},{"key":"290_CR32","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1002\/1529-0131(200012)43:12<2668::AID-ANR6>3.0.CO;2-E","volume":"43","author":"C Mindrescu","year":"2000","unstructured":"Mindrescu C, Thorbecke GJ, Klein MJ, Vilcek J, Wisniewski HG (2000) Amelioration of collagen-induced arthritis in DBA\/1\u00a0J mice by recombinant TSG-6, a tumor necrosis factor\/interleukin-1-inducible protein. Arthritis Rheum 43:2668\u20132677","journal-title":"Arthritis Rheum"},{"key":"290_CR33","doi-asserted-by":"crossref","first-page":"4589","DOI":"10.1242\/jcs.02579","volume":"118","author":"PN Moynagh","year":"2005","unstructured":"Moynagh PN (2005) The NF-kappa B pathway. J Cell Sci 118:4589\u20134592","journal-title":"J Cell Sci"},{"key":"290_CR34","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/art.1780390116","volume":"39","author":"D Mulherin","year":"1996","unstructured":"Mulherin D (1996) Synovial tissue macrophage populations and articular damage in rheumatoid arthritis. Arthritis Rheum 39:115\u2013124","journal-title":"Arthritis Rheum"},{"key":"290_CR35","doi-asserted-by":"crossref","first-page":"3367","DOI":"10.1016\/j.fct.2011.09.026","volume":"49","author":"R Nagalekshmi","year":"2011","unstructured":"Nagalekshmi R, Aditya MA, Chandrasekharan DK, Nair CKK (2011) Hepatoprotective activity of Andrographis paniculata and Swertia chirayita. Food Chem Toxicol 49:3367\u20133373","journal-title":"Food Chem Toxicol"},{"key":"290_CR36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3923\/crc.2011.1.15","volume":"3","author":"JS Negi","year":"2011","unstructured":"Negi JS, Singh P, Rawat B (2011) Chemical constituents and biological importance of Swertia: a review. Curr Res Chem 3:1\u201315","journal-title":"Curr Res Chem"},{"key":"290_CR37","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.jep.2014.01.035","volume":"152","author":"DD Obiri","year":"2014","unstructured":"Obiri DD, Osafo N, Ayande PG, Antwi AO (2014) Xylopia aethiopica (Annonaceae) fruit extract suppresses Freund\u2019s adjuvant-induced arthritis in Sprague-Dawley rats. J Ethnopharmacol 152:522\u20135231","journal-title":"J Ethnopharmacol"},{"key":"290_CR38","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s002960050097","volume":"19","author":"HS Ozturk","year":"1999","unstructured":"Ozturk HS, Cimen MY, Cimen OB, Kacmaz M, Durak I (1999) Oxidant\/antioxidant status of plasma samples from patients with rheumatoid arthritis. Rheumatol Int 19:35\u201337","journal-title":"Rheumatol Int"},{"key":"290_CR39","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3126\/eco.v17i0.4118","volume":"17","author":"S Phoboo","year":"2010","unstructured":"Phoboo S, Pinto MS, Bhowmik PC, Jha PK, Shetty K (2010) Quantification of major phytochemicals of Swertia chirayita, a medicinal plant from nepal. Ecoprint 17:59\u201368","journal-title":"Ecoprint"},{"key":"290_CR40","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s10787-009-8044-0","volume":"17","author":"M Ratheesh","year":"2009","unstructured":"Ratheesh M, Shyni GL, Helen A (2009) Methanolic extract of Ruta graveolens L inhibits inflammation and oxidative stress in adjuvant induced model of arthritis in rats. Inflammopharmacology 17:100\u2013105","journal-title":"Inflammopharmacology"},{"key":"290_CR41","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/ptr.1436","volume":"18","author":"P Saha","year":"2004","unstructured":"Saha P, Mandal S, Das A, Das PC, Das S (2004) Evaluation of anti-carcinogenic activity of Swertia chirata Buch. Ham, an Indian medicinal plant on DMBA-induced mouse skin carcinogenesis model. Phytother Res 18:373\u2013378","journal-title":"Phytother Res"},{"key":"290_CR42","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1002\/1529-0131(200112)44:12<2909::AID-ART479>3.0.CO;2-#","volume":"44","author":"D Salvemini","year":"2001","unstructured":"Salvemini D, Mazzon E, Dugo L, Serraino I, De SA, Caputi AP, Cuzzocrea S (2001) Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic. Arthritis Rheum 44:2909\u20132921","journal-title":"Arthritis Rheum"},{"key":"290_CR43","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1007\/s00011-014-0717-5","volume":"63","author":"S Saravanan","year":"2014","unstructured":"Saravanan S, Islam VI, Thirugnanasambantham K, Pazhanivel N, Raghuraman N, Paulraj MG, Ignacimuthu S (2014a) Swertiamarin ameliorates inflammation and osteoclastogenesis intermediates in IL-1\u03b2 induced rat fibroblast-like synoviocytes. Inflamm Res 63:451\u2013462","journal-title":"Inflamm Res"},{"key":"290_CR44","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/j.ejps.2014","volume":"2","author":"S Saravanan","year":"2014","unstructured":"Saravanan S, Islam VI, Babu NP, Pandikumar P, Thirugnanasambantham K, Chellappandian M, Raj CS, Paulraj MG, Ignacimuthu S (2014b) Swertiamarin attenuates inflammation mediators via modulating NF-\u03baB\/I \u03baB and JAK2\/STAT3 transcription factors in adjuvant induced arthritis. Eur J Pharm Sci 2:70\u201386. doi: 10.1016\/j.ejps.2014","journal-title":"Eur J Pharm Sci"},{"key":"290_CR45","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/S0140-6736(10)60826-4","volume":"376","author":"D Scott","year":"2010","unstructured":"Scott D, Wolfe F, Huizinga TWJ (2010) Rheumatoid arthritis. Lancet 376:1094\u20131108","journal-title":"Lancet"},{"key":"290_CR46","doi-asserted-by":"crossref","first-page":"3395","DOI":"10.1016\/j.fct.2011.08.013","volume":"49","author":"S Sharma","year":"2011","unstructured":"Sharma S, Sahu D, Das HR, Sharma D (2011) Amelioration of collagen-induced arthritis by Salix nigra bark extract via suppression of pro-inflammatory cytokines and oxidative stress. Food Chem Toxicol 49:3395\u20133406","journal-title":"Food Chem Toxicol"},{"key":"290_CR47","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1007\/s11916-013-0327-x","volume":"17","author":"O Summ","year":"2013","unstructured":"Summ O, Evers S (2013) Mechanism of action of indomethacin in indomethacin-responsive headaches. Curr Pain Headache Rep 17:327","journal-title":"Curr Pain Headache Rep"},{"key":"290_CR48","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1007\/s00296-001-0163-x","volume":"21","author":"S Taysi","year":"2002","unstructured":"Taysi S, Polat F, Gul M, Sari RA, Bakan E (2002) Lipid peroxidation, some extracellular antioxidants, and antioxidant enzymes in serum of patients with rheumatoid arthritis. Rheumatol Int 21:200\u2013204","journal-title":"Rheumatol Int"},{"key":"290_CR49","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","volume":"39","author":"M Valko","year":"2007","unstructured":"Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J (2007) Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 39:44\u201384","journal-title":"Int J Biochem Cell Biol"},{"key":"290_CR50","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.bmc.2010.10.053","volume":"19","author":"SH Venkatesha","year":"2011","unstructured":"Venkatesha SH, Berman BM, Moudgil KD (2011) Herbal medicinal products target defined biochemical and molecular mediators of inflammatory autoimmune arthritis. Bioorg Med Chem 19:21\u201329","journal-title":"Bioorg Med Chem"},{"key":"290_CR51","first-page":"647","volume":"7","author":"VK Verma","year":"2013","unstructured":"Verma VK, Sarwa KK, Kumar A, Md Zaman K (2013) Comparison of hepatoprotective activity of Swertia chirayita and Andrographis paniculata plant of North East India against CCl4 induced hepatotoxic rats. J Pharm Res 7:647\u2013653","journal-title":"J Pharm Res"},{"key":"290_CR52","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3109\/10408369009105897","volume":"28","author":"JS Warren","year":"1990","unstructured":"Warren JS (1990) Interleukins and tumor necrosis factor in inflammation. Crit Rev Clin Lab Sci 28:37\u201359","journal-title":"Crit Rev Clin Lab Sci"},{"key":"290_CR54","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.cbi.2007.06.032","volume":"169","author":"AS Yadav","year":"2007","unstructured":"Yadav AS, Bhatnagar D (2007) Chemo-preventive effect of Star anise in N-nitrosodiethylamine initiated and phenobarbital promoted hepato-carcinogenesis. Chem Biol Interact 169:207\u2013214","journal-title":"Chem Biol Interact"},{"key":"290_CR55","doi-asserted-by":"crossref","first-page":"569","DOI":"10.2174\/1381612053381927","volume":"11","author":"M Yingyu","year":"2005","unstructured":"Yingyu M, Pope RM (2005) The role of macrophages in rheumatoid arthritis. Curr Pharm Des 11:569\u2013580","journal-title":"Curr Pharm Des"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-016-0290-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10787-016-0290-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-016-0290-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,10]],"date-time":"2022-07-10T10:19:46Z","timestamp":1657448386000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10787-016-0290-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,14]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["290"],"URL":"https:\/\/doi.org\/10.1007\/s10787-016-0290-3","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,14]]}}}