{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T23:44:35Z","timestamp":1780443875480,"version":"3.54.1"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T00:00:00Z","timestamp":1599696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Fapesp","doi-asserted-by":"crossref","award":["Proc. 15\/03726-8 and 06\/06079-4"],"award-info":[{"award-number":["Proc. 15\/03726-8 and 06\/06079-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s10787-020-00752-0","type":"journal-article","created":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T17:03:05Z","timestamp":1599757385000},"page":"439-450","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Blutaparon portulacoides ethanolic extract reduced IL-1\u03b2 and inflammatory parameters induced by the Mycobacterium complex and carrageenan in mice"],"prefix":"10.1007","volume":"29","author":[{"given":"Roberto Mikio","family":"Kassuya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joyce Alencar Santos","family":"Radai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Fernando Benitez","family":"Macorini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viktor Krejci","family":"Nunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcos Jos\u00e9","family":"Salvador","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia Regina Ter\u00e7o","family":"Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Juliano","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00falio","family":"Croda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arielle Cristina","family":"Arena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8998-9219","authenticated-orcid":false,"given":"C\u00e2ndida Aparecida Leite","family":"Kassuya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,9,10]]},"reference":[{"key":"752_CR1","doi-asserted-by":"publisher","first-page":"2649","DOI":"10.1152\/jn.1999.82.5.2649","volume":"82","author":"D Andrew","year":"1999","unstructured":"Andrew D, Greenspan JD (1999) Mechanical and heat sensitization of cutaneous nociceptors after peripheral inflammation in the rat. J Neurop 82:2649\u20132656","journal-title":"J Neurop"},{"key":"752_CR2","first-page":"53915","volume":"5","author":"M Andrade","year":"2015","unstructured":"Andrade M, Benfeito S, Soares P et al (2015) Fine-tuning of the hydrophobicity of caffeic acid: studies on the antimicrobial activity against Staphylococcus aureus and Escherichia coli. Roy Soc Chem Advanc 5:53915\u201353925","journal-title":"Roy Soc Chem Advanc"},{"key":"752_CR3","doi-asserted-by":"crossref","unstructured":"Bertier RM, Dias RVC, Batista JS, Soto-Blanco B (2008) Intoxica\u00e7\u00e3o por pirrixiu (Blutaparon portulacoides) em ovinos. Arq Inst Biol 99\u2013102","DOI":"10.1590\/1808-1657v75p0992008"},{"key":"752_CR4","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1002\/iid3.9","volume":"1","author":"M-L Bourigault","year":"2013","unstructured":"Bourigault M-L, Segueni N, Rose S et al (2013) Relative contribution of IL-1\u03b1, IL-1\u03b2 and TNF to the host response to Mycobacterium tuberculosis and attenuated M. bovis BCG. Immun Inflamm Dis 1:47\u201362","journal-title":"Immun Inflamm Dis"},{"key":"752_CR5","unstructured":"Brasil. Minist\u00e9rio da Sa\u00fade (2009) Portal da Sa\u00fade. Programa Nacional de Plantas Medicinais e Fitoter\u00e1picos. https:\/\/portalsaude.saude.gov.br\/images\/pdf\/2015\/janeiro\/05\/ programa-nacional-plantas-medicinais-fitoter--picos-pnpmf.pdf"},{"key":"752_CR6","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/nri.2017.1","volume":"17","author":"DW Cain","year":"2017","unstructured":"Cain DW, Cidlowski JA (2017) Immune regulation by glucocorticoids. Nat Rev Immunol 17:233\u2013247","journal-title":"Nat Rev Immunol"},{"key":"752_CR7","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1016\/j.fct.2014.01.008","volume":"65","author":"F Campos","year":"2014","unstructured":"Campos F, Santos UP, Macorini LFB et al (2014) Antimicrobial, antioxidant and cytotoxic activities of propolis from Melipona orbignyi (Hymenoptera, Apidae). Food Chem Toxicol 65:374\u2013380","journal-title":"Food Chem Toxicol"},{"key":"752_CR8","doi-asserted-by":"crossref","unstructured":"Choi JH, Park SH, Jung JK et al (2017) Caffeic acid cyclohexylamide rescues lethal inflammation in septic mice through inhibition of I\u03baB kinase in innate immune process. Sci Report 41180","DOI":"10.1038\/srep41180"},{"key":"752_CR9","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1093\/jac\/dkr444","volume":"67","author":"MC Cholo","year":"2012","unstructured":"Cholo MC, Steel HC, Fourie PB et al (2012) Clofazimine: Current status and future prospects. J Antimicrob Chemotherap 67:290\u2013298","journal-title":"J Antimicrob Chemotherap"},{"key":"752_CR10","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1007\/s10787-016-0287-y","volume":"24","author":"S Choudhary","year":"2016","unstructured":"Choudhary S, Mourya A, Ahuja S et al (2016) Plausible anti-inflammatory mechanism of resveratrol and caffeic acid against chronic stress-induced insulin resistance in mice. Inflammopharmacol 24:347\u2013361","journal-title":"Inflammopharmacol"},{"key":"752_CR11","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1128\/CMR.10.4.742","volume":"10","author":"JH Curfs","year":"1997","unstructured":"Curfs JH, Meis JFJ, Hoogkamp-Korstange A (1997) A primer on cytokines: sources, receptors, effects, and inducers. Clinic Microb Rev 10:742\u2013780","journal-title":"Clinic Microb Rev"},{"issue":"12","key":"752_CR12","doi-asserted-by":"publisher","first-page":"2922","DOI":"10.1128\/AAC.43.12.2922","volume":"43","author":"MH Cynamon","year":"1999","unstructured":"Cynamon MH, Zhang Y, Harpster T, Cheng S, DeStefano MS (1999) High-dose isoniazid therapy for isoniazid-resistant murine Mycobacterium tuberculosis infection. Antimicrob Agents Chemother 43(12):2922\u20132924","journal-title":"Antimicrob Agents Chemother"},{"issue":"2","key":"752_CR13","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1016\/S0304-3959(00)00276-1","volume":"87","author":"I Decosterd","year":"2000","unstructured":"Decosterd I, Woolf CJ (2000) Spared nerve injury: an animal model of persistent peripheral neuropathic pain. Pain 87(2):149\u2013158","journal-title":"Pain"},{"issue":"10","key":"752_CR14","doi-asserted-by":"publisher","first-page":"1474","DOI":"10.3109\/13880209.2014.986687","volume":"53","author":"D Dey","year":"2015","unstructured":"Dey D, Ray R, Hazra B (2015) Antimicrobial activity of pomegranate fruit constituents against drug-resistant Mycobacterium tuberculosis and \u03b2-lactamase producing Klebsiella pneumoniae. Pharm Biol 53(10):1474\u20131480","journal-title":"Pharm Biol"},{"issue":"1","key":"752_CR15","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1002\/path.1711040103","volume":"104","author":"ML Di Rosa","year":"1971","unstructured":"Di Rosa ML, Giroud JP, Willoughby DA (1971) Studies of the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J Pathol 104(1):15\u201329","journal-title":"J Pathol"},{"issue":"1","key":"752_CR16","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1016\/S0031-9422(99)00390-8","volume":"53","author":"EO Ferreira","year":"2000","unstructured":"Ferreira EO, Dias DA (2000) A methylenedioxyflavonol from aerial parts of Blutaparon portulacoides. Phytochemistry 53(1):145\u2013147","journal-title":"Phytochemistry"},{"issue":"22","key":"752_CR17","doi-asserted-by":"publisher","first-page":"3441","DOI":"10.1002\/rcm.5248","volume":"25","author":"F Ferreres","year":"2011","unstructured":"Ferreres F, Gil-Izquierdo A, Valent\u00e3o P, Andrade PB (2011) Structural characterization of phenolics and betacyanins in Gomphrena globosa by high-performance liquid chromatography-diode array detection\/electrospray ionization multi-stage mass spectrometry. Rapid Commun Mass Spectrom 25(22):3441\u20133446","journal-title":"Rapid Commun Mass Spectrom"},{"issue":"1","key":"752_CR18","first-page":"e01413","volume":"62","author":"C Genestet","year":"2017","unstructured":"Genestet C, Ader F, Pichat C et al (2017) Assessing the combined antibacterial effect of isoniazid and rifampin on four Mycobacterium tuberculosis strains using In Vitro experiments and response-surface modeling. Antimicrob Agents Chemother 62(1):e01413\u2013e1417","journal-title":"Antimicrob Agents Chemother"},{"issue":"24","key":"752_CR19","doi-asserted-by":"publisher","first-page":"4599","DOI":"10.1111\/bph.14867","volume":"176","author":"SR Khan","year":"2019","unstructured":"Khan SR, Manialawy Y, Siraki AG (2019) Isoniazid and host immune system interactions: A proposal for a novel comprehensive mode of action. Br J Pharmacol 176(24):4599\u20134608","journal-title":"Br J Pharmacol"},{"issue":"5","key":"752_CR20","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1016\/j.tube.2013.05.002","volume":"93","author":"N Krishnan","year":"2013","unstructured":"Krishnan N, Robertson BD, Thwaites G (2013) Pathways of IL-1\u03b2 secretion by macrophages infected with clinical Mycobacterium tuberculosis strains. Tuberc (Edinb) 93(5):538\u2013547","journal-title":"Tuberc (Edinb)"},{"key":"752_CR21","doi-asserted-by":"publisher","first-page":"112418","DOI":"10.1016\/j.jep.2019.112418","volume":"249","author":"AM Kuraoka-Oliveira","year":"2020","unstructured":"Kuraoka-Oliveira AM, Radai JAS, Leit\u00e3o MM, Lima Cardoso CA, Silva-Filho SE, Leite Kassuya CA (2020) Anti-inflammatory and anti-arthritic activity in extract from the leaves of Eriobotrya japonica. J Ethnopharmacol 249:112418","journal-title":"J Ethnopharmacol"},{"key":"752_CR22","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.imbio.2017.10.046","volume":"223","author":"N Lampiasi","year":"2018","unstructured":"Lampiasi N, Montana G (2018) An in vitro inflammation model to study the Nrf2 and NF-\u03baB crosstalk in presence of ferulic acid as modulator. Immunobiology 223:349\u2013355","journal-title":"Immunobiology"},{"key":"752_CR23","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.intimp.2017.02.007","volume":"45","author":"YM Liu","year":"2017","unstructured":"Liu YM, Shen JD, Xu LP et al (2017) Ferulic acid inhibits neuro-inflammation in mice exposed to chronic unpredictable mild stress. Int Immunopharmacol 45:128\u2013134","journal-title":"Int Immunopharmacol"},{"issue":"2","key":"752_CR24","doi-asserted-by":"publisher","first-page":"392","DOI":"10.3109\/14756366.2011.650168","volume":"28","author":"A Maresca","year":"2013","unstructured":"Maresca A, Vullo D, Scozzafava A et al (2013) Inhibition of the \u03b2-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids. J Enzyme Inhib Med Chem 28(2):392\u2013396","journal-title":"J Enzyme Inhib Med Chem"},{"issue":"Sup6","key":"752_CR25","doi-asserted-by":"publisher","first-page":"S4","DOI":"10.12968\/jowc.2018.27.Sup6.S4","volume":"27","author":"DJ Marmitt","year":"2018","unstructured":"Marmitt DJ, Bitencourt S, Silva ADCE et al (2018) The healing properties of medicinal plants used in the Brazilian public health system: a systematic review. J Wound Care 27(Sup6):S4\u2013S13","journal-title":"J Wound Care"},{"key":"752_CR26","unstructured":"Marson CV, Boas EV, Zamuner S, Salvador MJ (2009) Preparo de uma formula\u00e7\u00e3o t\u00f3pica e avalia\u00e7\u00e3o antiinflamat\u00f3ria do extrato Blutaparon portulacoides. In: XIII Encontro Latino de Inicia\u00e7\u00e3o Cient\u00edfica, IX Encontro Latino Americano de P\u00f3s Gradua\u00e7\u00e3o e III Encontro Latino de Inicia\u00e7\u00e3o Cient\u00edfica Junior"},{"key":"752_CR27","doi-asserted-by":"publisher","first-page":"612","DOI":"10.3892\/br.2017.909","volume":"6","author":"S Mathur","year":"2017","unstructured":"Mathur S, Hoskins C (2017) Drug development: Lessons from nature. Biomed Report 6:612\u2013614","journal-title":"Biomed Report"},{"key":"752_CR28","first-page":"115","volume":"225","author":"CJ Morris","year":"2003","unstructured":"Morris CJ (2003) Carrageenan-induced paw edema in the rat and mouse. Methods Mol Biol 225:115\u2013121","journal-title":"Methods Mol Biol"},{"key":"752_CR29","unstructured":"National Committee for Clinical Laboratory Standards (NCCLS) (2002) Performance standards for antimicrobial susceptibility testing. Inf Supplements. 100\u2013112"},{"issue":"4","key":"752_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.4172\/2161-1068.1000251","volume":"7","author":"BV Nikonenko","year":"2017","unstructured":"Nikonenko BV, Bocharova IV, Korotetskaya MV, Averbakh MM, Apt AS (2017) Efficacy of isoniazid therapy in mice with different genetic susceptibility to infection. Mycobact Dis 7(4):1\u20134","journal-title":"Mycobact Dis"},{"key":"752_CR31","unstructured":"OECD (2008) Organisation for Economic Co-operation and Development In: CHEMICALS, O. G. F. T. T. O. (Ed.). Guideline 425: Acute Oral Toxicity \u2013 Up-and-Down-Procedure (UDP), Paris: Head of Publications Service, 27"},{"issue":"04","key":"752_CR32","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1055\/s-2003-38885","volume":"69","author":"DBD Oliveira","year":"2003","unstructured":"Oliveira DBD, de Almeida AP, Gabriela L et al (2003) First isolation of a symmetrical glycosylated methylene bis flavonoid. Planta Med 69(04):382\u2013384","journal-title":"Planta Med"},{"issue":"8","key":"752_CR33","doi-asserted-by":"publisher","first-page":"2720","DOI":"10.1128\/AAC.46.8.2720-2722.2002","volume":"46","author":"JC Palomino","year":"2002","unstructured":"Palomino JC, Martin A, Camacho M et al (2002) Resazurin microtiter assay plate: simple and inexpensive method for detection of drug resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother 46(8):2720\u20132722","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"752_CR34","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1590\/S1678-91992009000300013","volume":"15","author":"IC Pereira","year":"2009","unstructured":"Pereira IC, Barbosa AM, Salvador MJ et al (2009) Anti-inflammatory activity of Blutaparon portulacoides ethanolic extract against the inflammatory reaction induced by Bothrops jararacussu venom and isolated myotoxins BTHTX-I and II. J Venom Anim Toxins incl Trop Dis 15(3):527\u2013545","journal-title":"J Venom Anim Toxins incl Trop Dis"},{"key":"752_CR35","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1590\/1519-6984.177447","volume":"79","author":"IDSL Pio","year":"2019","unstructured":"Pio IDSL, Lavor AL, Damasceno CMD et al (2019) Traditional knowledge and uses of medicinal plants by the inhabitants of the islands of the S\u00e3o Francisco river, Brazil and preliminary analysis of Rhaphiodon echinus (Lamiaceae). Braz J Biol 79:87\u201399","journal-title":"Braz J Biol"},{"issue":"2","key":"752_CR36","doi-asserted-by":"publisher","first-page":"331","DOI":"10.1038\/sj.bjp.0705650","volume":"142","author":"I Posadas","year":"2004","unstructured":"Posadas I, Bucci M, Roviezzo F et al (2004) Carrageenan-induced mouse paw oedema is biphasic, age-weight dependent and displays differential nitric oxide cyclooxygenase-2 expression. Br J Pharmacol 142(2):331\u2013338","journal-title":"Br J Pharmacol"},{"issue":"6","key":"752_CR37","doi-asserted-by":"publisher","first-page":"566","DOI":"10.1078\/09447110260573227","volume":"9","author":"MJ Salvador","year":"2002","unstructured":"Salvador MJ, Ferreira EO, Pral EM et al (2002) Bioactivity of crude extracts and some constituents of Blutaparon portulacoides (Amaranthaceae). Phytomedicine 9(6):566\u2013571","journal-title":"Phytomedicine"},{"key":"752_CR38","doi-asserted-by":"publisher","DOI":"10.2174\/978160805114411201010124","volume-title":"Bioactive chemical constituents and biotechnological production of secondary metabolites in Amaranthaceae Plants","author":"MJ Salvador","year":"2012","unstructured":"Salvador MJ, Andreazza NL, Pascoal ACRF et al (2012) Bioactive chemical constituents and biotechnological production of secondary metabolites in Amaranthaceae Plants. Bentham Science Publishers Ltd, Gomphreneae Tribe. Benth"},{"key":"752_CR39","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1016\/j.toxrep.2017.10.005","volume":"31","author":"U Saleem","year":"2017","unstructured":"Saleem U, Amin S, Ahmad B et al (2017) Acute oral toxicity evaluation of aqueous ethanolic extract of Saccharum munja Roxb. roots in albino mice as per OECD 425 TG. Toxicol Reports 31:580\u2013585","journal-title":"Toxicol Reports"},{"key":"752_CR40","first-page":"99","volume":"09","author":"JC Siqueira","year":"1987","unstructured":"Siqueira JC (1987) Import\u00e2ncia aliment\u00edcia e medicinal das amarant\u00e1ceas do Brasil. Act Biologica Leopold 09:99","journal-title":"Act Biologica Leopold"},{"issue":"5","key":"752_CR41","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1006\/mcpr.1993.1058","volume":"7","author":"CA Spargo","year":"1993","unstructured":"Spargo CA, Haaland PD, Jurgensen SR et al (1993) Chemiluminescent detection of strand displacement amplified DNA from species comprising the Mycobacterium tuberculosis complex. Mol Cell Probes 7(5):395\u2013404","journal-title":"Mol Cell Probes"},{"key":"752_CR42","doi-asserted-by":"publisher","first-page":"2069","DOI":"10.3389\/fimmu.2018.02069","volume":"9","author":"G Teskey","year":"2018","unstructured":"Teskey G, Cao R, Islamoglu H et al (2018) The synergistic effects of the glutathione precursor, NAC and first-line antibiotics in the granulomatous response against Mycobacterium tuberculosis. Front Immunol 9:2069","journal-title":"Front Immunol"},{"key":"752_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3390\/molecules22061001","volume":"22","author":"CH Tseng","year":"2017","unstructured":"Tseng CH, Tung CW, Wu CH et al (2017) Discovery of Indeno[1,2-c]quinoline derivatives as potent dual antituberculosis and anti-inflammatory agents. Molecules 22:1\u201315","journal-title":"Molecules"},{"issue":"3","key":"752_CR44","doi-asserted-by":"publisher","first-page":"711","DOI":"10.3181\/00379727-143-37397","volume":"143","author":"R Vinegar","year":"1973","unstructured":"Vinegar R, Truax JF, Selph JL (1973) Some quantitative temporal characteristics of carrageenin-induced pleurisy in the rat. Proc Soc Exp Biol Med 143(3):711\u2013714","journal-title":"Proc Soc Exp Biol Med"},{"issue":"3","key":"752_CR45","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1590\/S0100-879X2004000300017","volume":"37","author":"GG Vivancos","year":"2004","unstructured":"Vivancos GG, Verri WA, Cunha TM et al (2004) An electronic pressure-meter nociception paw test for rats. Braz J Med Biol Res 37(3):391\u2013399","journal-title":"Braz J Med Biol Res"},{"issue":"1","key":"752_CR46","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1038\/s41467-017-00930-9","volume":"8","author":"Z Xiahou","year":"2017","unstructured":"Xiahou Z, Wang X, Shen J et al (2017) NMI and IFP35 serve as proinflammatory DAMPs during cellular infection and injury. Nat Commun 8(1):950","journal-title":"Nat Commun"},{"key":"752_CR47","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1016\/j.pbb.2015.02.016","volume":"132","author":"ML Yrbas","year":"2015","unstructured":"Yrbas ML, Morucci F, Alonso R, Gorzalczany S (2015) Pharmacological mechanism underlying the antinociceptive activity of vanillic acid. Pharmacol Biochem Behav 132:88\u201395","journal-title":"Pharmacol Biochem Behav"},{"key":"752_CR48","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/AIA.0b013e318034194e","volume":"45","author":"JM Zhang","year":"2007","unstructured":"Zhang JM, An J (2007) Cytokines, inflammation and pain. Int Anesthesiol Clin 45:27\u201337","journal-title":"Int Anesthesiol Clin"},{"issue":"1","key":"752_CR49","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s13318-012-0106-9","volume":"38","author":"Y Zhou","year":"2013","unstructured":"Zhou Y, Jiao Y, Wei YH et al (2013) Effects of pyridoxine on the intestinal absorption and pharmacokinetics of isoniazid in rats. Eur J Drug Metab Pharmacokinet 38(1):5\u201313","journal-title":"Eur J Drug Metab Pharmacokinet"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-020-00752-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-020-00752-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-020-00752-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,17]],"date-time":"2022-04-17T22:04:36Z","timestamp":1650233076000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-020-00752-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,10]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["752"],"URL":"https:\/\/doi.org\/10.1007\/s10787-020-00752-0","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,10]]},"assertion":[{"value":"8 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standard"}},{"value":"The author(s) confirm that this article content has no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}