{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T01:40:02Z","timestamp":1780537202305,"version":"3.54.1"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T00:00:00Z","timestamp":1650844800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T00:00:00Z","timestamp":1650844800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100019135","name":"Universitas Bengkulu","doi-asserted-by":"crossref","award":["1811\/UN30.15\/PG\/2021"],"award-info":[{"award-number":["1811\/UN30.15\/PG\/2021"]}],"id":[{"id":"10.13039\/100019135","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1007\/s10787-022-00982-4","type":"journal-article","created":{"date-parts":[[2022,4,25]],"date-time":"2022-04-25T10:03:56Z","timestamp":1650881036000},"page":"2139-2144","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Gastroprotective activities of Peperomia pellucida L. and Pachyrhizus erosus L. extracts combination on ethanol-induced rats"],"prefix":"10.1007","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8052-8646","authenticated-orcid":false,"given":"Reza","family":"Pertiwi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agung Giri","family":"Samudra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noval Kurnia","family":"Wati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aanisah","family":"Hanuun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salprima","family":"Yudha S","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doni","family":"Notriawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Risky Hadi","family":"Wibowo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,4,25]]},"reference":[{"key":"982_CR1","volume-title":"Goodman & Gillman\u2019s the pharmacological basis of theurapeutics","author":"LL Brunton","year":"2006","unstructured":"Brunton LL, Lazo JS, Parker KL (2006) Goodman & Gillman\u2019s the pharmacological basis of theurapeutics. McGraw Hill, New York"},{"key":"982_CR2","first-page":"726","volume-title":"Pharmacodynamic basic of herbal medicine","author":"N Ebadi","year":"2007","unstructured":"Ebadi N (2007) Pharmacodynamic basic of herbal medicine. CRC Press, London New York-Washington D.C, p 726"},{"issue":"124","key":"982_CR3","first-page":"1","volume":"49","author":"R Indraswary","year":"2011","unstructured":"Indraswary R (2011) Effects of concentration of fennel fruit extract (Foeniculum vulgare Mill) Topical on Epitheliization of Wound Healing Gingiva Labial Rat Sprague Dawley in Vivo. Majalah Ilmiah Sultan Agung 49(124):1\u201314","journal-title":"Majalah Ilmiah Sultan Agung"},{"issue":"1","key":"982_CR4","doi-asserted-by":"publisher","first-page":"58","DOI":"10.3390\/antiox11010058","volume":"11","author":"V Jaiswal","year":"2021","unstructured":"Jaiswal V, Chauhan S, Lee HJ (2021) The bioactivity and phytochemicals of Pachyrhizus erosus (L.) Urb.: a multifunctional underutilized crop plant. Antioxidants 11(1):58","journal-title":"Antioxidants"},{"issue":"3","key":"982_CR5","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1177\/039463200802100304","volume":"21","author":"D Kalogeromitros","year":"2008","unstructured":"Kalogeromitros D, Makris M, Chliva C, Aggelides X, Kempuraj D, Theoharides TC (2008) A quercetin containing supplement reduces niacin-induced flush in humans. Int J Immunopathol Pharmacol 21(3):509\u2013514","journal-title":"Int J Immunopathol Pharmacol"},{"key":"982_CR6","volume-title":"Harrison\u2019s gastroenterology and hepatology","author":"DL Longo","year":"2010","unstructured":"Longo DL, Fauci AS (2010) Harrison\u2019s gastroenterology and hepatology. The McGraw-Hill Companies Inc, New York"},{"key":"982_CR7","unstructured":"Lukitaningsih E (2009) The Exploration of Whitening and Sun Screening Compounds in Bengkoang Roots (Pachyrhizus erosus). Thesis. Deutschen Akademischen Austauschdienstes) Wurzburg"},{"key":"982_CR8","doi-asserted-by":"publisher","first-page":"312","DOI":"10.12928\/pharmaciana.v11i3.20104","volume":"11","author":"R Pertiwi","year":"2021","unstructured":"Pertiwi R, Hanuun A, Kurniawati N, Siti Khodijah P, Fita Lestari D, Fitriani D, Notriawan D (2021) The effect of Raphanus sativus and Pachyrhizus erosus juice combination on the ethanol-induced gastric of mice. Pharmaciana 11:312\u2013320. https:\/\/doi.org\/10.12928\/pharmaciana.v11i3.20104","journal-title":"Pharmaciana"},{"key":"982_CR9","doi-asserted-by":"publisher","first-page":"56","DOI":"10.20473\/jfiki.v5i22018.56-61","volume":"5","author":"R Pertiwi","year":"2019","unstructured":"Pertiwi R, Saputra HM (2019) The effect of bengkuang bulbs (Pachyrhizus erosus L.) on the histopathology picture of the gastric of Mencit (Mus musculus L.) with a peptic ulcer model. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia 5:56\u201361. https:\/\/doi.org\/10.20473\/jfiki.v5i22018.56-61","journal-title":"Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia"},{"key":"982_CR10","volume-title":"Scientific rampage flowers FK UKI (Nomor 7)","author":"F Rachmawati","year":"2018","unstructured":"Rachmawati F, Rantelino V (2018) Scientific rampage flowers FK UKI (Nomor 7). Fakultas Kedokteran Universitas Kristen Indonesia, Jakarta"},{"issue":"9","key":"982_CR11","doi-asserted-by":"publisher","first-page":"11327","DOI":"10.3390\/molecules180911327","volume":"18","author":"R Rojas-Mart\u00ednez","year":"2013","unstructured":"Rojas-Mart\u00ednez R, Arrieta J, Cruz-Antonio L, Arrieta-Baez D, Vel\u00e1zquez-M\u00e9ndez AM, S\u00e1nchez-Mendoza ME (2013) Dillapiole, isolated from Peperomia pellucida, shows gastroprotector activity against ethanol-induced gastric lesions in Wistar rats. Molecules 18(9):11327\u201311337","journal-title":"Molecules"},{"key":"982_CR12","first-page":"678","volume":"2","author":"AH Roslida","year":"2009","unstructured":"Roslida AH, Aini NZ (2009) Evaluation of gastroprotective effect of the ethanolic extract of Peperomia pellucida (L) Kunth. Pharmacologyonline 2:678\u2013686","journal-title":"Pharmacologyonline"},{"issue":"2","key":"982_CR13","first-page":"75","volume":"16","author":"MN Saptarini","year":"2011","unstructured":"Saptarini MN, Suryasaputra D (2011) Analysis of Pepino cider antiulser protection ratio (Solanum muricatum Aiton) using mice as a model of animal trial. Majalah Obat Tradisional 16(2):75\u201380","journal-title":"Majalah Obat Tradisional"},{"issue":"6","key":"982_CR14","doi-asserted-by":"publisher","first-page":"657","DOI":"10.3109\/00365521.2015.1019918","volume":"50","author":"P Sipponen","year":"2015","unstructured":"Sipponen P, Maaros HI (2015) Chronic Gastritis. Scand J Gastroenterol 50(6):657\u2013667","journal-title":"Scand J Gastroenterol"},{"issue":"3","key":"982_CR15","doi-asserted-by":"publisher","first-page":"3203","DOI":"10.3390\/ijms13033203","volume":"13","author":"FH Souza","year":"2012","unstructured":"Souza FH, Jesus NZ, Gomes IF, Almeida LTJ, Morais Lima GR, Barbosa Filho JM (2012) Tannins, peptic ulcers and related mechanisms. Int J Mol Sci 13(3):3203\u20133228","journal-title":"Int J Mol Sci"},{"issue":"6","key":"982_CR16","doi-asserted-by":"publisher","first-page":"614","DOI":"10.1108\/01443570210427659","volume":"22","author":"KC Tan","year":"2002","unstructured":"Tan KC, Lyman SB, Wisner JD (2002) Supply chain management: a strategic perspective. Int J Oper Prod Manag 22(6):614\u2013631","journal-title":"Int J Oper Prod Manag"},{"key":"982_CR17","unstructured":"Tarigan P (2001) Tukak Gaster. Buku Ajar Penyakit Dalam. Pusat Penerbitan Fakultas Kedokteran, vol 1, pp 338\u2013344 (Jakarta)"},{"issue":"2","key":"982_CR18","doi-asserted-by":"publisher","first-page":"73","DOI":"10.24198\/ijpst.v7i2.22416","volume":"7","author":"W Widyaningsih","year":"2020","unstructured":"Widyaningsih W, Afdaliah SN, dan (2020) Gastroprotective effect of green algae extract (Ulva lactuca L) on gastric rats. Indones J Pharm Sci Technol 7(2):73\u201380","journal-title":"Indones J Pharm Sci Technol"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-022-00982-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-022-00982-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-022-00982-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T21:11:01Z","timestamp":1669410661000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-022-00982-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,25]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,12]]}},"alternative-id":["982"],"URL":"https:\/\/doi.org\/10.1007\/s10787-022-00982-4","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,25]]},"assertion":[{"value":"8 March 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 April 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This study was performed in line with the principles of the International Association for the Study of Pain (IASP) Guidelines for the Use of Animals in Research. Approval was granted by the Ethics Committee of the University of Bengkulu\u00a0(18 Oct 2021\/No: 240\/UN30.14.9\/LT\/2021).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}