{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T20:13:39Z","timestamp":1792700019498,"version":"4.5.0"},"reference-count":94,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T00:00:00Z","timestamp":1686873600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s10787-023-01257-2","type":"journal-article","created":{"date-parts":[[2023,6,16]],"date-time":"2023-06-16T07:02:22Z","timestamp":1686898942000},"page":"1761-1778","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Emerging trends in combination strategies with phototherapy in advanced psoriasis management"],"prefix":"10.1007","volume":"31","author":[{"given":"Ratnam","family":"Sreya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Nene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vrushali","family":"Pathade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashi Bala","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0723-4363","authenticated-orcid":false,"given":"Saurabh","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,16]]},"reference":[{"key":"1257_CR1","first-page":"519","volume":"51","author":"T Afifi","year":"2005","unstructured":"Afifi T, de Gannes G, Huang C, Zhou Y (2005) Topical therapies for psoriasis: evidence-based review. Can Fam Phys 51:519\u2013525","journal-title":"Can Fam Phys"},{"key":"1257_CR2","doi-asserted-by":"publisher","first-page":"546","DOI":"10.3109\/09546634.2016.1163318","volume":"27","author":"P Aggarwal","year":"2016","unstructured":"Aggarwal P, Aggarwal K, Jain VK (2016) Tacalcitol: a useful adjunct to narrow band ultraviolet B phototherapy in psoriasis. J Dermatol Treat 27:546\u2013551. https:\/\/doi.org\/10.3109\/09546634.2016.1163318","journal-title":"J Dermatol Treat"},{"key":"1257_CR3","doi-asserted-by":"publisher","first-page":"1531","DOI":"10.1111\/ijd.12444","volume":"53","author":"HR Al-Hamamy","year":"2014","unstructured":"Al-Hamamy HR, Al-Mashhadani SA, Mustafa IN (2014) Comparative study of the effect of narrowband ultraviolet B phototherapy plus methotrexate vs. narrowband ultraviolet B alone and methotrexate alone in the treatment of plaque-type psoriasis. Int J Dermatol 53:1531\u20131535. https:\/\/doi.org\/10.1111\/ijd.12444","journal-title":"Int J Dermatol"},{"key":"1257_CR4","unstructured":"Arndt KA, Leboit PE, Wintroub BU, Stein Gold LF (2016) Topical therapies for psoriasis: improving management strategies and patient adherence (guest editor)"},{"key":"1257_CR5","first-page":"957","volume":"16","author":"J Bagel","year":"2017","unstructured":"Bagel J, Nelson E, Keegan BR (2017) Apremilast and narrowband ultraviolet-B combination therapy for treating moderate-to-severe plaque psoriasis. J Drugs Dermatol 16:957\u2013962","journal-title":"J Drugs Dermatol"},{"key":"1257_CR6","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1080\/09546634.2016.1177162","volume":"28","author":"S Bajaj","year":"2017","unstructured":"Bajaj S, Gautam RK, Khurana A et al (2017) Effect of narrow band ultraviolet B phototherapy on T helper 17 cell specific cytokines (interleukins-17, 22 and 23) in psoriasis vulgaris. J Dermatol Treat 28:14\u201317. https:\/\/doi.org\/10.1080\/09546634.2016.1177162","journal-title":"J Dermatol Treat"},{"key":"1257_CR7","first-page":"9","volume":"5","author":"DMW Balak","year":"2014","unstructured":"Balak DMW (2014) Fumaric acid esters in the management of psoriasis. Psoriasis Targets Ther 5:9\u201323","journal-title":"Psoriasis Targets Ther"},{"key":"1257_CR8","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1016\/j.cyto.2014.12.014","volume":"73","author":"J Baliwag","year":"2015","unstructured":"Baliwag J, Barnes DH, Johnston A (2015) Cytokines in psoriasis. Cytokine 73:342\u2013350","journal-title":"Cytokine"},{"key":"1257_CR9","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1016\/j.jphotobiol.2016.05.023","volume":"161","author":"A Batycka-Baran","year":"2016","unstructured":"Batycka-Baran A, Besgen P, Wolf R et al (2016) The effect of phototherapy on systemic inflammatory process in patients with plaque psoriasis. J Photochem Photobiol B 161:396\u2013401. https:\/\/doi.org\/10.1016\/j.jphotobiol.2016.05.023","journal-title":"J Photochem Photobiol B"},{"key":"1257_CR10","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1002\/der2.84","volume":"2","author":"CR Buechler","year":"2021","unstructured":"Buechler CR, Veenstra J, Stein Gold L (2021) New topical therapies for psoriasis. Dermatol Rev 2:262\u2013268. https:\/\/doi.org\/10.1002\/der2.84","journal-title":"Dermatol Rev"},{"key":"1257_CR11","doi-asserted-by":"publisher","first-page":"547","DOI":"10.12968\/bjon.2020.29.10.547","volume":"29","author":"J Campbell","year":"2020","unstructured":"Campbell J (2020) Safe and effective use of phototherapy and photochemotherapy in the treatment of psoriasis. Br J Nurs 29:547\u2013552. https:\/\/doi.org\/10.12968\/bjon.2020.29.10.547","journal-title":"Br J Nurs"},{"key":"1257_CR12","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/s41423-019-0291-4","volume":"17","author":"L Chen","year":"2020","unstructured":"Chen L, Shen Z (2020) Tissue-resident memory T cells and their biological characteristics in the recurrence of inflammatory skin disorders. Cell Mol Immunol 17:64\u201375","journal-title":"Cell Mol Immunol"},{"key":"1257_CR13","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3899\/jrheum.200124","volume":"96","author":"LC Coates","year":"2020","unstructured":"Coates LC, Merola JF, Grieb SM et al (2020) Methotrexate in psoriasis and psoriatic arthritis. J Rheumatol 96:31\u201335. https:\/\/doi.org\/10.3899\/jrheum.200124","journal-title":"J Rheumatol"},{"key":"1257_CR14","doi-asserted-by":"publisher","first-page":"392","DOI":"10.5114\/pdia.2014.47121","volume":"31","author":"M Czarnecka-Operacz","year":"2014","unstructured":"Czarnecka-Operacz M, Sadowska-Przytocka A (2014) The possibilities and principles of methotrexate treatment of psoriasis\u2014the updated knowledge. Postepy Dermatol Alergol 31:392\u2013400. https:\/\/doi.org\/10.5114\/pdia.2014.47121","journal-title":"Postepy Dermatol Alergol"},{"key":"1257_CR15","doi-asserted-by":"publisher","first-page":"582","DOI":"10.1002\/cbin.11137","volume":"43","author":"MS D\u2019Arcy","year":"2019","unstructured":"D\u2019Arcy MS (2019) Cell death: a review of the major forms of apoptosis, necrosis and autophagy. Cell Biol Int 43:582\u2013592","journal-title":"Cell Biol Int"},{"key":"1257_CR16","doi-asserted-by":"publisher","first-page":"1286","DOI":"10.1038\/s41590-018-0256-2","volume":"19","author":"T Dainichi","year":"2018","unstructured":"Dainichi T, Kitoh A, Otsuka A et al (2018) The epithelial immune microenvironment (EIME) in atopic dermatitis and psoriasis. Nat Immunol 19:1286\u20131298","journal-title":"Nat Immunol"},{"key":"1257_CR17","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1590\/abd1806-4841.20186723","volume":"93","author":"S Dayal","year":"2018","unstructured":"Dayal S, Kaura R, Sahu P, Jain VK (2018) Tazarotene gel with narrow-band UVB phototherapy: a synergistic combination in psoriasis. An Bras Dermatol 93:385\u2013390. https:\/\/doi.org\/10.1590\/abd1806-4841.20186723","journal-title":"An Bras Dermatol"},{"key":"1257_CR18","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.ejps.2016.10.025","volume":"96","author":"S Doppalapudi","year":"2017","unstructured":"Doppalapudi S, Jain A, Chopra DK, Khan W (2017) Psoralen loaded liposomal nanocarriers for improved skin penetration and efficacy of topical PUVA in psoriasis. Eur J Pharm Sci 96:515\u2013529. https:\/\/doi.org\/10.1016\/j.ejps.2016.10.025","journal-title":"Eur J Pharm Sci"},{"key":"1257_CR19","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/980419","author":"S Dubois Declercq","year":"2013","unstructured":"Dubois Declercq S, Pouliot R (2013) Promising new treatments for psoriasis. Sci World J. https:\/\/doi.org\/10.1155\/2013\/980419","journal-title":"Sci World J"},{"key":"1257_CR20","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1016\/j.jaad.2019.04.042","volume":"81","author":"CA Elmets","year":"2019","unstructured":"Elmets CA, Lim HW, Stoff B et al (2019) Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis with phototherapy. J Am Acad Dermatol 81:775\u2013804. https:\/\/doi.org\/10.1016\/j.jaad.2019.04.042","journal-title":"J Am Acad Dermatol"},{"key":"1257_CR21","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1111\/cei.13449","volume":"201","author":"JM Fletcher","year":"2020","unstructured":"Fletcher JM, Moran B, Petrasca A, Smith CM (2020) IL-17 in inflammatory skin diseases psoriasis and hidradenitis suppurativa. Clin Exp Immunol 201:121\u2013134","journal-title":"Clin Exp Immunol"},{"key":"1257_CR22","unstructured":"Gagan Jot Kaur SBPSUKN (2023) Randomized double blinded placebo controlled comparative study of topical steroid plus bath PUVA versus bath PUVA and placebo cream. J Pak Assoc Dermatol"},{"key":"1257_CR23","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1111\/phpp.12125","volume":"30","author":"P Gahalaut","year":"2014","unstructured":"Gahalaut P, Soodan PS, Mishra N et al (2014) Clinical efficacy of psoralen + sunlight vs. combination of isotretinoin and psoralen + sunlight for the treatment of chronic plaque-type psoriasis vulgaris: a randomized hospital-based study. Photodermatol Photoimmunol Photomed 30:294\u2013301. https:\/\/doi.org\/10.1111\/phpp.12125","journal-title":"Photodermatol Photoimmunol Photomed"},{"key":"1257_CR24","doi-asserted-by":"publisher","first-page":"664","DOI":"10.1080\/09546634.2018.1544702","volume":"30","author":"M Ghiasi","year":"2019","unstructured":"Ghiasi M, Ebrahimi S, Lajevardi V et al (2019) Efficacy and safety of pioglitazone plus phototherapy versus phototherapy in patients with plaque type psoriasis: a double blinded randomized controlled trial. J Dermatol Treat 30:664\u2013667. https:\/\/doi.org\/10.1080\/09546634.2018.1544702","journal-title":"J Dermatol Treat"},{"key":"1257_CR25","doi-asserted-by":"publisher","first-page":"79","DOI":"10.4103\/ijdd.ijdd_26_20","volume":"7","author":"A Gnaneshwar Rao","year":"2021","unstructured":"Gnaneshwar Rao A, Jagadevapuram K (2021) Comparative study of PUVA and NB-UVB in the management of chronic plaque psoriasis. Indian J Drugs Dermatol 7:79. https:\/\/doi.org\/10.4103\/ijdd.ijdd_26_20","journal-title":"Indian J Drugs Dermatol"},{"key":"1257_CR26","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24071388","author":"C Gomez","year":"2019","unstructured":"Gomez C, Muangnoi C, Sorasitthiyanukarn FN et al (2019) Synergistic effects of photo-irradiation and curcumin-chitosan\/alginate nanoparticles on tumor necrosis factor-alpha-induced psoriasis-like proliferation of keratinocytes. Molecules. https:\/\/doi.org\/10.3390\/molecules24071388","journal-title":"Molecules"},{"key":"1257_CR27","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1080\/09546630701364768","volume":"19","author":"AB Gottlieb","year":"2008","unstructured":"Gottlieb AB, Chao C, Dann F (2008) Psoriasis comorbidities. J Dermatol Treat 19:5\u201321","journal-title":"J Dermatol Treat"},{"key":"1257_CR28","doi-asserted-by":"publisher","first-page":"532","DOI":"10.1016\/j.clindermatol.2016.05.002","volume":"34","author":"A Grzybowski","year":"2016","unstructured":"Grzybowski A, Sak J, Pawlikowski J (2016) A brief report on the history of phototherapy. Clin Dermatol 34:532\u2013537. https:\/\/doi.org\/10.1016\/j.clindermatol.2016.05.002","journal-title":"Clin Dermatol"},{"key":"1257_CR29","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1016\/j.clindermatol.2007.08.007","volume":"25","author":"JE Gudjonsson","year":"2007","unstructured":"Gudjonsson JE, Elder JT (2007) Psoriasis: epidemiology. Clin Dermatol 25:535\u2013546. https:\/\/doi.org\/10.1016\/j.clindermatol.2007.08.007","journal-title":"Clin Dermatol"},{"key":"1257_CR30","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1111\/bjd.19747","volume":"185","author":"H Hamm","year":"2021","unstructured":"Hamm H, Wilsmann-Theis D, Tsianakas A et al (2021) Efficacy and safety of fumaric acid esters in young patients aged 10\u201317 years with moderate-to-severe plaque psoriasis: a randomized, double-blinded, placebo-controlled trial. Br J Dermatol 185:62\u201373. https:\/\/doi.org\/10.1111\/bjd.19747","journal-title":"Br J Dermatol"},{"key":"1257_CR31","doi-asserted-by":"publisher","first-page":"30","DOI":"10.18231\/j.ijced.2020.008","volume":"6","author":"R Hassan","year":"2020","unstructured":"Hassan R, Ali S, Kallan F et al (2020) A study to compare the efficacy and safety of narrow band-UVB alone as well as in combination with topical calcipotriol in patients with psoriasis vulgaris. IP Indian J Clin Exp Dermatol 6:30\u201334. https:\/\/doi.org\/10.18231\/j.ijced.2020.008","journal-title":"IP Indian J Clin Exp Dermatol"},{"key":"1257_CR32","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1038\/s41577-019-0162-3","volume":"19","author":"AW Ho","year":"2019","unstructured":"Ho AW, Kupper TS (2019) T cells and the skin: from protective immunity to inflammatory skin disorders. Nat Rev Immunol 19:490\u2013502","journal-title":"Nat Rev Immunol"},{"key":"1257_CR33","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1046\/j.1365-2230.2001.00828.x","volume":"26","author":"H H\u00f6nigsmann","year":"2001","unstructured":"H\u00f6nigsmann H (2001) Phototherapy for psoriasis. Clin Exp Dermatol 26:343\u2013350. https:\/\/doi.org\/10.1046\/j.1365-2230.2001.00828.x","journal-title":"Clin Exp Dermatol"},{"key":"1257_CR34","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1039\/c2pp25120e","volume":"12","author":"H H\u00f6nigsmann","year":"2013","unstructured":"H\u00f6nigsmann H (2013) History of phototherapy in dermatology. Photochem Photobiol Sci 12:16\u201321","journal-title":"Photochem Photobiol Sci"},{"key":"1257_CR35","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1111\/j.1468-3083.2009.03358.x","volume":"24","author":"EJ Horn","year":"2010","unstructured":"Horn EJ, Domm S, Katz HI et al (2010) Topical corticosteroids in psoriasis: strategies for improving safety. J Eur Acad Dermatol Venereol 24:119\u2013124","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1257_CR36","doi-asserted-by":"publisher","first-page":"100041","DOI":"10.1016\/j.crphar.2021.100041","volume":"2","author":"H Jain","year":"2021","unstructured":"Jain H, Bhat AR, Dalvi H et al (2021) Repurposing approved therapeutics for new indication: addressing unmet needs in psoriasis treatment. Curr Res Pharmacol Drug Discov 2:100041","journal-title":"Curr Res Pharmacol Drug Discov"},{"key":"1257_CR37","doi-asserted-by":"publisher","unstructured":"Jankowiak Beata Kowalewska El B, Krajewska-Ku\u0142ak Dzmitry Khvorikzbieta F (2020) Stigmatization and quality of life in patients with psoriasis. Dermatol Ther. https:\/\/doi.org\/10.6084\/m9.figshare.11890032","DOI":"10.6084\/m9.figshare.11890032"},{"key":"1257_CR38","first-page":"106324","volume":"62","author":"SL Jyothi","year":"2021","unstructured":"Jyothi SL, Krishna KL, Ameena Shirin VK et al (2021) Drug delivery systems for the treatment of psoriasis: current status and prospects. J Drug Deliv Sci Technol 62:106324","journal-title":"J Drug Deliv Sci Technol"},{"key":"1257_CR39","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1111\/1346-8138.14096","volume":"45","author":"M Kamata","year":"2018","unstructured":"Kamata M, Tada Y (2018) Safety of biologics in psoriasis. J Dermatol 45:279\u2013286","journal-title":"J Dermatol"},{"key":"1257_CR40","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1111\/ijd.14246","volume":"58","author":"SB Kaushik","year":"2019","unstructured":"Kaushik SB, Lebwohl MG (2019) Review of safety and efficacy of approved systemic psoriasis therapies. Int J Dermatol 58:649\u2013658","journal-title":"Int J Dermatol"},{"key":"1257_CR41","doi-asserted-by":"publisher","first-page":"12","DOI":"10.3126\/njdvl.v13i1.14298","volume":"13","author":"DK Khadka","year":"2016","unstructured":"Khadka DK, Agrawal S, Dhali TK (2016) Methotrexate plus narrow band ultraviolet B (NBUVB) versus methotrexate alone in the treatment of moderate to severe plaque psoriasis: a randomized clinical trial. Nepal J Dermatol Venereol Leprol 13:12\u201323. https:\/\/doi.org\/10.3126\/njdvl.v13i1.14298","journal-title":"Nepal J Dermatol Venereol Leprol"},{"key":"1257_CR42","first-page":"278","volume":"63","author":"WB Kim","year":"2017","unstructured":"Kim WB, Jerome D, Yeung J (2017) Diagnosis and management of psoriasis. Can Fam Phys 63:278\u2013285","journal-title":"Can Fam Phys"},{"key":"1257_CR43","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1067\/mjd.2000.107940","volume":"43","author":"JYM Koo","year":"2000","unstructured":"Koo JYM, Lowe NJ, Lew-Kaya DA et al (2000) Tazarotene plus UVB phototherapy in the treatment of psoriasis. J Am Acad Dermatol 43:821\u2013828. https:\/\/doi.org\/10.1067\/mjd.2000.107940","journal-title":"J Am Acad Dermatol"},{"key":"1257_CR44","doi-asserted-by":"publisher","first-page":"443","DOI":"10.1007\/s00403-018-1832-x","volume":"310","author":"Z Kwan","year":"2018","unstructured":"Kwan Z, Bong YB, Tan LL et al (2018) Determinants of quality of life and psychological status in adults with psoriasis. Arch Dermatol Res 310:443\u2013451. https:\/\/doi.org\/10.1007\/s00403-018-1832-x","journal-title":"Arch Dermatol Res"},{"key":"1257_CR45","doi-asserted-by":"publisher","first-page":"1999","DOI":"10.1517\/14656566.2010.492778","volume":"11","author":"PM Laws","year":"2010","unstructured":"Laws PM, Young HS (2010) Topical treatment of psoriasis. Expert Opin Pharmacother 11:1999\u20132009","journal-title":"Expert Opin Pharmacother"},{"key":"1257_CR46","doi-asserted-by":"publisher","first-page":"649","DOI":"10.1067\/mjd.2001.117047","volume":"45","author":"M Lebwohl","year":"2001","unstructured":"Lebwohl M, Ali S (2001) Treatment of psoriasis. Part 2. Systemic therapies. J Am Acad Dermatol 45:649\u2013664. https:\/\/doi.org\/10.1067\/mjd.2001.117047","journal-title":"J Am Acad Dermatol"},{"key":"1257_CR47","doi-asserted-by":"publisher","first-page":"6414","DOI":"10.3390\/ijms14036414","volume":"14","author":"CH Lee","year":"2013","unstructured":"Lee CH, Wu SB, Hong CH et al (2013) Molecular mechanisms of UV-induced apoptosis and its effects on skin residential cells: the implication in UV-based phototherapy. Int J Mol Sci 14:6414\u20136435. https:\/\/doi.org\/10.3390\/ijms14036414","journal-title":"Int J Mol Sci"},{"key":"1257_CR48","first-page":"169","volume":"22","author":"HJ Lee","year":"2021","unstructured":"Lee HJ, Hong YJ, Kim M (2021) Angiogenesis in chronic inflammatory skin disorders. Int J Mol Sci 22:169","journal-title":"Int J Mol Sci"},{"key":"1257_CR49","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3109\/09546634.2013.860210","volume":"26","author":"E Levin","year":"2015","unstructured":"Levin E, Debbaneh M, Malakouti M et al (2015) Supraerythemogenic excimer laser in combination with clobetasol spray and calcitriol ointment for the treatment of generalized plaque psoriasis: interim results of an open label pilot study. J Dermatol Treat 26:16\u201318. https:\/\/doi.org\/10.3109\/09546634.2013.860210","journal-title":"J Dermatol Treat"},{"key":"1257_CR50","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.1007\/s11010-022-04417-0","volume":"477","author":"X Lin","year":"2022","unstructured":"Lin X, Meng X, Song Z, Lin J (2022) Peroxisome proliferator-activator receptor \u03b3 and psoriasis, molecular and cellular biochemistry. Mol Cell Biochem 477:1905\u20131920. https:\/\/doi.org\/10.1007\/s11010-022-04417-0","journal-title":"Mol Cell Biochem"},{"key":"1257_CR51","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1038\/nature05663","volume":"445","author":"MA Lowes","year":"2007","unstructured":"Lowes MA, Bowcock AM, Krueger JG (2007) Pathogenesis and therapy of psoriasis. Nature 445:866\u2013873","journal-title":"Nature"},{"key":"1257_CR52","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1146\/annurev-immunol-032713-120225","volume":"32","author":"MA Lowes","year":"2014","unstructured":"Lowes MA, Su\u00e1rez-Fari\u00f1as M, Krueger JG (2014) Immunology of psoriasis. Annu Rev Immunol 32:227\u2013255","journal-title":"Annu Rev Immunol"},{"key":"1257_CR53","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1111\/ced.12408","volume":"39","author":"M Lynch","year":"2014","unstructured":"Lynch M, Tobin AM, Ahern T et al (2014a) Sitagliptin for severe psoriasis. Clin Exp Dermatol 39:841\u2013842","journal-title":"Clin Exp Dermatol"},{"key":"1257_CR54","doi-asserted-by":"publisher","DOI":"10.1186\/s13063-016-1157-z","author":"M Lynch","year":"2016","unstructured":"Lynch M, Ahern TB, Timoney I et al (2016) Dipeptidyl peptidase-4 inhibition and narrow-band ultraviolet-B light in psoriasis (DINUP): study protocol for a randomised controlled trial. Trials. https:\/\/doi.org\/10.1186\/s13063-016-1157-z","journal-title":"Trials"},{"key":"1257_CR55","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1111\/j.1468-3083.2009.03486.x","volume":"24","author":"R Mahajan","year":"2010","unstructured":"Mahajan R, Kaur I, Kanwar A (2010) Methotrexate\/narrowband UVB phototherapy combination vs. narrowband UVB phototherapy in the treatment of chronic plaque-type psoriasis\u2014a randomized single-blinded placebo-controlled study. J Eur Acad Dermatol Venereol 24:595\u2013600. https:\/\/doi.org\/10.1111\/j.1468-3083.2009.03486.x","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1257_CR56","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.clindermatol.2009.04.003","volume":"28","author":"H Matz","year":"2010","unstructured":"Matz H (2010) Phototherapy for psoriasis: what to choose and how to use: facts and controversies. Clin Dermatol 28:73\u201380. https:\/\/doi.org\/10.1016\/j.clindermatol.2009.04.003","journal-title":"Clin Dermatol"},{"key":"1257_CR57","doi-asserted-by":"publisher","first-page":"287","DOI":"10.1111\/1346-8138.14213","volume":"45","author":"A Morita","year":"2018","unstructured":"Morita A (2018) Current developments in phototherapy for psoriasis. J Dermatol 45:287\u2013292","journal-title":"J Dermatol"},{"key":"1257_CR58","doi-asserted-by":"publisher","first-page":"362","DOI":"10.1046\/j.1365-2230.2001.00835.x","volume":"26","author":"U Mrowietz","year":"2001","unstructured":"Mrowietz U (2001) Advances in systemic therapy for psoriasis. Clin Exp Dermatol 26:362\u2013367. https:\/\/doi.org\/10.1046\/j.1365-2230.2001.00835.x","journal-title":"Clin Exp Dermatol"},{"key":"1257_CR59","doi-asserted-by":"crossref","unstructured":"Nadia A, Elsherif 1 IMESAE-D (2015) Narrow band UVB monotherapy versus topical calcipotriol ointment combined with narrow band UVB phototherapy for treatment of psoriasis vulgaris. Ibnosina J Med Biomed Sci","DOI":"10.4103\/1947-489X.210269"},{"key":"1257_CR60","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1016\/j.clindermatol.2007.08.003","volume":"25","author":"L Naldi","year":"2007","unstructured":"Naldi L, Gambini D (2007) The clinical spectrum of psoriasis. Clin Dermatol 25:510\u2013518. https:\/\/doi.org\/10.1016\/j.clindermatol.2007.08.003","journal-title":"Clin Dermatol"},{"key":"1257_CR61","doi-asserted-by":"publisher","unstructured":"Nast A, Boehncke W-H, Mrowietz U et al (2012) S3-Guidelines on the treatment of psoriasis vulgaris (English version). Update guidelines on the treatment of psoriasis vulgaris S1 1 preface. JDDG. https:\/\/doi.org\/10.1111\/j.1610-0379.2012.07919.x","DOI":"10.1111\/j.1610-0379.2012.07919.x"},{"key":"1257_CR62","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1586\/17469872.1.1.63","volume":"1","author":"AL Neimann","year":"2006","unstructured":"Neimann AL, Porter SB, Gelfand JM (2006a) The epidemiology of psoriasis. Expert Rev Dermatol 1:63\u201375. https:\/\/doi.org\/10.1586\/17469872.1.1.63","journal-title":"Expert Rev Dermatol"},{"key":"1257_CR63","doi-asserted-by":"publisher","first-page":"829","DOI":"10.1016\/j.jaad.2006.08.040","volume":"55","author":"AL Neimann","year":"2006","unstructured":"Neimann AL, Shin DB, Wang X et al (2006b) Prevalence of cardiovascular risk factors in patients with psoriasis. J Am Acad Dermatol 55:829\u2013835. https:\/\/doi.org\/10.1016\/j.jaad.2006.08.040","journal-title":"J Am Acad Dermatol"},{"key":"1257_CR64","doi-asserted-by":"publisher","DOI":"10.7241\/ourd.20153.76","author":"SB Nejad","year":"2015","unstructured":"Nejad SB, Ghadim HH, Ezzati A et al (2015) Comparison between the effects of Daivonex cream alone and its combination with narrowband ultraviolet B in treatment of psoriasis. Our Dermatol Online. https:\/\/doi.org\/10.7241\/ourd.20153.76","journal-title":"Our Dermatol Online"},{"key":"1257_CR65","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.pbiomolbio.2006.02.009","volume":"92","author":"M Norval","year":"2006","unstructured":"Norval M (2006) The mechanisms and consequences of ultraviolet-induced immunosuppression. Prog Biophys Mol Biol 92:108\u2013118","journal-title":"Prog Biophys Mol Biol"},{"key":"1257_CR66","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1111\/1346-8138.14139","volume":"45","author":"E Ogawa","year":"2018","unstructured":"Ogawa E, Sato Y, Minagawa A, Okuyama R (2018) Pathogenesis of psoriasis and development of treatment. J Dermatol 45:264\u2013272","journal-title":"J Dermatol"},{"key":"1257_CR88","unstructured":"Ontario Health (Quality) (2020) Home narrowband ultraviolet B phototherapy for photoresponsive skin conditions: A health technology assessment"},{"key":"1257_CR67","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1046\/j.1365-2133.1999.140S54001.x","volume":"140","author":"ORTONNE","year":"1999","unstructured":"ORTONNE (1999) Recent developments in the understanding of the pathogenesis of psoriasis. Br J Dermatol 140:1\u20137. https:\/\/doi.org\/10.1046\/j.1365-2133.1999.140S54001.x","journal-title":"Br J Dermatol"},{"key":"1257_CR68","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1111\/j.1365-4632.2011.05257.x","volume":"51","author":"\u0130 \u00d6zkan","year":"2012","unstructured":"\u00d6zkan \u0130, K\u00f6se O, \u00d6zmen \u0130, Arca E (2012) Efficacy and safety of non-laser, targeted UVB phototherapy alone and in combination with psoralen gel or calcipotriol ointment in the treatment of localized, chronic, plaque-type psoriasis. Int J Dermatol 51:609\u2013613. https:\/\/doi.org\/10.1111\/j.1365-4632.2011.05257.x","journal-title":"Int J Dermatol"},{"key":"1257_CR69","unstructured":"Peter Kozub M (2011) Systemic therapy of psoriasis: methotrexate"},{"key":"1257_CR70","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1111\/j.1468-3083.2011.04061.x","volume":"25","author":"K Reich","year":"2011","unstructured":"Reich K, Bewley A (2011) What is new in topical therapy for psoriasis? J Eur Acad Dermatol Venereol 25:15\u201320","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"1257_CR71","doi-asserted-by":"crossref","unstructured":"Reichrath J, Holick MF (2018) Psoriasis and other skin diseases. In: Vitamin D. Elsevier, London, pp 1037\u20131051","DOI":"10.1016\/B978-0-12-809963-6.00109-7"},{"key":"1257_CR72","doi-asserted-by":"publisher","first-page":"6","DOI":"10.3390\/ijms20061475","volume":"20","author":"A Rendon","year":"2019","unstructured":"Rendon A, Sch\u00e4kel K (2019) Psoriasis pathogenesis and treatment. Int J Mol Sci 20:6","journal-title":"Int J Mol Sci"},{"key":"1257_CR73","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1590\/abd1806-4841.20186981","volume":"93","author":"A Salman","year":"2018","unstructured":"Salman A, Yucelten AD, Sarac E et al (2018) Impact of psoriasis in the quality of life of children, adolescents and their families: a cross-sectional study. An Bras Dermatol 93:819\u2013823. https:\/\/doi.org\/10.1590\/abd1806-4841.20186981","journal-title":"An Bras Dermatol"},{"key":"1257_CR74","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s40257-014-0064-x","volume":"15","author":"LF Sandoval","year":"2014","unstructured":"Sandoval LF, Pierce A, Feldman SR (2014) Systemic therapies for psoriasis: an evidence-based update. Am J Clin Dermatol 15:165\u2013180","journal-title":"Am J Clin Dermatol"},{"key":"1257_CR75","doi-asserted-by":"publisher","unstructured":"Sascha DMWB, Aurora G, Laura Salgado-Boquete P (2020) Long-term safety of oral systemic therapies for psoriasis: a comprehensive review of the literature. Dermatol Ther. https:\/\/doi.org\/10.6084\/m9.figshare.12409523","DOI":"10.6084\/m9.figshare.12409523"},{"key":"1257_CR76","doi-asserted-by":"publisher","first-page":"1764","DOI":"10.3389\/fimmu.2019.01764","volume":"10","author":"MP Sch\u00f6n","year":"2019","unstructured":"Sch\u00f6n MP (2019) Adaptive and innate immunity in psoriasis and other inflammatory disorders. Front Immunol 10:1764","journal-title":"Front Immunol"},{"key":"1257_CR77","doi-asserted-by":"publisher","first-page":"735","DOI":"10.1007\/s12013-013-9563-2","volume":"67","author":"OG Shaker","year":"2013","unstructured":"Shaker OG, Khairallah M, Rasheed HM et al (2013) Antiangiogenic effect of methotrexate and PUVA on psoriasis. Cell Biochem Biophys 67:735\u2013742. https:\/\/doi.org\/10.1007\/s12013-013-9563-2","journal-title":"Cell Biochem Biophys"},{"key":"1257_CR78","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1136\/bmj.333.7564.380","volume":"333","author":"CH Smith","year":"2006","unstructured":"Smith CH, Barker JNWN (2006) Psoriasis and its management. BMJ 333:380\u2013384. https:\/\/doi.org\/10.1136\/bmj.333.7564.380","journal-title":"BMJ"},{"key":"1257_CR79","doi-asserted-by":"publisher","first-page":"528","DOI":"10.3109\/09546634.2015.1034069","volume":"26","author":"A Soliman","year":"2015","unstructured":"Soliman A, Nofal EA, Nofal A et al (2015) Combination therapy of methotrexate plus NBUVB phototherapy is more effective than methotrexate monotherapy in the treatment of chronic plaque psoriasis. J Dermatol Treat 26:528\u2013534. https:\/\/doi.org\/10.3109\/09546634.2015.1034069","journal-title":"J Dermatol Treat"},{"key":"1257_CR80","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.jaad.2020.04.095","volume":"84","author":"AE Torres","year":"2021","unstructured":"Torres AE, Lyons AB, Hamzavi IH, Lim HW (2021) Role of phototherapy in the era of biologics. J Am Acad Dermatol 84:479\u2013485","journal-title":"J Am Acad Dermatol"},{"key":"1257_CR81","doi-asserted-by":"publisher","first-page":"235","DOI":"10.4103\/2229-5178.209622","volume":"8","author":"R Torsekar","year":"2017","unstructured":"Torsekar R, Gautam M (2017) Topical therapies in psoriasis. Indian Dermatol Online J 8:235. https:\/\/doi.org\/10.4103\/2229-5178.209622","journal-title":"Indian Dermatol Online J"},{"key":"1257_CR82","doi-asserted-by":"publisher","first-page":"682","DOI":"10.1111\/bjd.16106","volume":"178","author":"S Tzaneva","year":"2018","unstructured":"Tzaneva S, Geroldinger A, Trattner H, Tanew A (2018) Fumaric acid esters in combination with a 6-week course of narrowband ultraviolet B provides an accelerated response compared with fumaric acid esters monotherapy in patients with moderate-to-severe plaque psoriasis: a randomized prospective clinical study. Br J Dermatol 178:682\u2013688. https:\/\/doi.org\/10.1111\/bjd.16106","journal-title":"Br J Dermatol"},{"key":"1257_CR83","doi-asserted-by":"publisher","first-page":"561018","DOI":"10.1155\/2012\/561018","volume":"2012","author":"L Uva","year":"2012","unstructured":"Uva L, Miguel D, Pinheiro C et al (2012) Mechanisms of action of topical corticosteroids in psoriasis. Int J Endocrinol 2012:561018","journal-title":"Int J Endocrinol"},{"key":"1257_CR84","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1046\/j.1365-2249.2004.02310.x","volume":"135","author":"H Valdimarsson","year":"2004","unstructured":"Valdimarsson H, Gudjonsson JE, Johnston A et al (2004) Immunopathogenic mechanisms in psoriasis. Clin Exp Immunol 135:1\u20138. https:\/\/doi.org\/10.1046\/j.1365-2249.2004.02310.x","journal-title":"Clin Exp Immunol"},{"key":"1257_CR85","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1001\/jamadermatol.2020.2311","volume":"156","author":"MEC van Winden","year":"2020","unstructured":"van Winden MEC, van der Schoot LS, van de L\u2019Isle AM et al (2020) Effectiveness and safety of systemic therapy for psoriasis in older adults a systematic review. JAMA Dermatol 156:1229\u20131239","journal-title":"JAMA Dermatol"},{"key":"1257_CR86","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s13671-018-0209-x","volume":"7","author":"VM Verallo-Rowell","year":"2018","unstructured":"Verallo-Rowell VM, Katalbas SS, Evangelista MTP, Dayrit JF (2018) Review update on topical therapy for psoriasis. Curr Dermatol Rep 7:24\u201336","journal-title":"Curr Dermatol Rep"},{"key":"1257_CR87","doi-asserted-by":"publisher","first-page":"17","DOI":"10.3390\/jcm10173822","volume":"10","author":"TT Vu","year":"2021","unstructured":"Vu TT, Koguchi-Yoshioka H, Watanabe R (2021) Skin-resident memory t cells: pathogenesis and implication for the treatment of psoriasis. J Clin Med 10:17","journal-title":"J Clin Med"},{"key":"1257_CR89","doi-asserted-by":"publisher","first-page":"180","DOI":"10.1111\/ddg.12837","volume":"15","author":"P Weisenseel","year":"2017","unstructured":"Weisenseel P, Reich K, Griemberg W et al (2017) Wirksamkeit und Sicherheit von Fumars\u00e4ureestern in Kombination mit Phototherapie bei Patienten mit moderater bis schwerer Plaque-Psoriasis (FAST). JDDG-J German Soc Dermatol 15:180\u2013186. https:\/\/doi.org\/10.1111\/ddg.12837","journal-title":"JDDG-J German Soc Dermatol"},{"key":"1257_CR90","doi-asserted-by":"publisher","first-page":"6","DOI":"10.2310\/7750.2012.11124","volume":"17","author":"T Wong","year":"2013","unstructured":"Wong T, Hsu L, Liao W (2013a) Phototherapy in psoriasis: a review of mechanisms of action. J Cutan Med Surg 17:6\u201312. https:\/\/doi.org\/10.2310\/7750.2012.11124","journal-title":"J Cutan Med Surg"},{"key":"1257_CR91","volume-title":"Imaging technologies and transdermal delivery in skin disorders","author":"W-M Woo","year":"2019","unstructured":"Woo W-M (2019) Imaging technologies and transdermal delivery in skin disorders. Wiley, New York"},{"key":"1257_CR92","doi-asserted-by":"publisher","first-page":"13328","DOI":"10.1038\/s41598-021-92599-w","volume":"11","author":"C Xi","year":"2021","unstructured":"Xi C, Xiong C, Wang H et al (2021) Combination of retinoids and narrow-band ultraviolet B inhibits matrix metalloproteinase 13 expression in HaCaT keratinocytes and a mouse model of psoriasis. Sci Rep 11:13328. https:\/\/doi.org\/10.1038\/s41598-021-92599-w","journal-title":"Sci Rep"},{"key":"1257_CR93","doi-asserted-by":"publisher","first-page":"553","DOI":"10.1586\/1744666X.2015.1026894","volume":"11","author":"O Y\u00e9lamos","year":"2015","unstructured":"Y\u00e9lamos O, Puig L (2015) Systemic methotrexate for the treatment of psoriasis. Expert Rev Clin Immunol 11:553\u2013563. https:\/\/doi.org\/10.1586\/1744666X.2015.1026894","journal-title":"Expert Rev Clin Immunol"},{"key":"1257_CR94","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/s10103-017-2360-1","volume":"33","author":"P Zhang","year":"2018","unstructured":"Zhang P, Wu MX (2018) A clinical review of phototherapy for psoriasis. Lasers Med Sci 33:173\u2013180","journal-title":"Lasers Med Sci"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-023-01257-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-023-01257-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-023-01257-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,17]],"date-time":"2023-07-17T11:24:22Z","timestamp":1689593062000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-023-01257-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,16]]},"references-count":94,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["1257"],"URL":"https:\/\/doi.org\/10.1007\/s10787-023-01257-2","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,16]]},"assertion":[{"value":"17 April 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have not disclosed any competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Enquiries about data availability should be directed to the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Data availability"}}]}}