{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:54:17Z","timestamp":1772240057869,"version":"3.50.1"},"reference-count":92,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T00:00:00Z","timestamp":1730505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T00:00:00Z","timestamp":1730505600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Natural Science Foundation of Chongqing China","award":["CSTB2022NSCQ-MSX1493"],"award-info":[{"award-number":["CSTB2022NSCQ-MSX1493"]}]},{"name":"Chongqing University of Technology Postgraduate Quality Development Action Plan Funding Results","award":["gzlcx20243220"],"award-info":[{"award-number":["gzlcx20243220"]}]},{"name":"Chongqing Post-graduate Research Innovation Project","award":["CYS240719"],"award-info":[{"award-number":["CYS240719"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1007\/s10787-024-01587-9","type":"journal-article","created":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T11:03:22Z","timestamp":1730545402000},"page":"183-194","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Thiostrepton: multifaceted biological activities and its applications in treatment of inflammatory diseases"],"prefix":"10.1007","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9209-9609","authenticated-orcid":false,"given":"Aiminuer","family":"Asikaer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cai","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,11,2]]},"reference":[{"issue":"4","key":"1587_CR1","doi-asserted-by":"publisher","first-page":"1338","DOI":"10.1128\/aac.01096-10","volume":"55","author":"MN Aminake","year":"2011","unstructured":"Aminake MN, Schoof S, Sologub L, Leubner M, Kirschner M, Arndt HD, Pradel G (2011) Thiostrepton and derivatives exhibit antimalarial and gametocytocidal activity by dually targeting parasite proteasome and apicoplast. Antimicrob Agents Chemother 55(4):1338\u20131348. https:\/\/doi.org\/10.1128\/aac.01096-10","journal-title":"Antimicrob Agents Chemother"},{"issue":"5229","key":"1587_CR2","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/225233a0","volume":"225","author":"B Anderson","year":"1970","unstructured":"Anderson B, Hodgkin DC, Viswamitra MA (1970) The structure of thiostrepton. Nature 225(5229):233\u2013235. https:\/\/doi.org\/10.1038\/225233a0","journal-title":"Nature"},{"key":"1587_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2021.174661","author":"C Bailly","year":"2022","unstructured":"Bailly C (2022) The bacterial thiopeptide thiostrepton. An update of its mode of action, pharmacological properties and applications. Eur J Pharmacol. https:\/\/doi.org\/10.1016\/j.ejphar.2021.174661","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"1587_CR4","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1007\/bf01975121","volume":"36","author":"F Benazet","year":"1980","unstructured":"Benazet F, Cartier M, Florent J, Godard C, Jung G, Lunel J, Ninet L (1980) Nosiheptide, a sulfur-containing peptide antibiotic isolated from Streptomyces actuosus 40037. Experientia 36(4):414\u2013416. https:\/\/doi.org\/10.1007\/bf01975121","journal-title":"Experientia"},{"issue":"8","key":"1587_CR5","doi-asserted-by":"publisher","first-page":"2027","DOI":"10.4049\/jimmunol.2100175","volume":"207","author":"S Bhaumik","year":"2021","unstructured":"Bhaumik S, Mickael ME, Moran M, Spell M, Basu R (2021) ROR\u03b3t promotes Foxp3 expression by antagonizing the effector program in colonic regulatory T cells. J Immunol 207(8):2027\u20132038. https:\/\/doi.org\/10.4049\/jimmunol.2100175","journal-title":"J Immunol"},{"issue":"3","key":"1587_CR6","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1038\/s41429-020-00387-x","volume":"74","author":"DCK Chan","year":"2021","unstructured":"Chan DCK, Burrows LL (2021) Thiopeptides: antibiotics with unique chemical structures and diverse biological activities. J Antibiot (Tokyo) 74(3):161\u2013175. https:\/\/doi.org\/10.1038\/s41429-020-00387-x","journal-title":"J Antibiot (Tokyo)"},{"issue":"1","key":"1587_CR7","first-page":"63","volume":"6","author":"MJ Cron","year":"1956","unstructured":"Cron MJ, Whitehead DG, Hooper IR, Heinemann B, Lein J (1956) Bryamycin, a new antibiotic. Antibiot Chemother (Northfield) 6(1):63\u201367","journal-title":"Antibiot Chemother (Northfield)"},{"issue":"1","key":"1587_CR8","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1038\/s41467-021-21344-8","volume":"12","author":"E Dekel","year":"2021","unstructured":"Dekel E, Yaffe D, Rosenhek-Goldian I, Ben-Nissan G, Ofir-Birin Y, Morandi MI, Regev-Rudzki N (2021) 20S proteasomes secreted by the malaria parasite promote its growth. Nat Commun 12(1):1172. https:\/\/doi.org\/10.1038\/s41467-021-21344-8","journal-title":"Nat Commun"},{"issue":"11","key":"1587_CR9","doi-asserted-by":"publisher","first-page":"10387","DOI":"10.1007\/s11033-022-07751-0","volume":"49","author":"F Demirtas Korkmaz","year":"2022","unstructured":"Demirtas Korkmaz F, Dogan Turacli I, Esendagli G, Ekmekci A (2022) Effects of thiostrepton alone or in combination with selumetinib on triple-negative breast cancer metastasis. Mol Biol Rep 49(11):10387\u201310397. https:\/\/doi.org\/10.1007\/s11033-022-07751-0","journal-title":"Mol Biol Rep"},{"key":"1587_CR10","first-page":"554","volume":"3","author":"R Donovick","year":"1955","unstructured":"Donovick R, Pagano JF, Stout HA, Weinstein MJ (1955) Thiostrepton, a new antibiotic. I. in vitro studies. Antibiot Annu 3:554\u2013559","journal-title":"Antibiot Annu"},{"key":"1587_CR11","first-page":"560","volume":"3","author":"JD Dutcher","year":"1955","unstructured":"Dutcher JD, Vandeputte J (1955) Thiostrepton, a new antibiotic. II. isolation and chemical characterization. Antibiot Annu 3:560\u2013561","journal-title":"Antibiot Annu"},{"key":"1587_CR12","doi-asserted-by":"publisher","DOI":"10.1097\/mpa.0000000000002314","author":"M Ebrahim","year":"2024","unstructured":"Ebrahim M, Werge MP, Novovic S, Amin NEL, Karstensen JG, J\u00f8rgensen HL (2024) Prediction of admission to intensive care unit and 1-year mortality after acute pancreatitis with walled-off pancreatic necrosis: a retrospective, single-center cohort study. Pancreas. https:\/\/doi.org\/10.1097\/mpa.0000000000002314","journal-title":"Pancreas"},{"issue":"19","key":"1587_CR13","doi-asserted-by":"publisher","first-page":"4199","DOI":"10.1158\/0008-5472.Can-20-1158","volume":"80","author":"N El-Nikhely","year":"2020","unstructured":"El-Nikhely N, Karger A, Sarode P, Singh I, Weigert A, Wietelmann A, Savai R (2020) Metastasis-associated protein 2 represses NF-\u03baB to reduce lung tumor growth and inflammation. Cancer Res 80(19):4199\u20134211. https:\/\/doi.org\/10.1158\/0008-5472.Can-20-1158","journal-title":"Cancer Res"},{"key":"1587_CR14","doi-asserted-by":"publisher","first-page":"4035516","DOI":"10.1155\/2023\/4035516","volume":"2023","author":"K Esparza","year":"2023","unstructured":"Esparza K, Oliveira SD, Castellon M, Minshall RD, Onyuksel H (2023) Thiostrepton-nanomedicine, a TLR9 inhibitor, attenuates sepsis-induced inflammation in mice. Mediators Inflamm 2023:4035516. https:\/\/doi.org\/10.1155\/2023\/4035516","journal-title":"Mediators Inflamm"},{"key":"1587_CR15","doi-asserted-by":"publisher","first-page":"136","DOI":"10.1016\/j.bcp.2017.04.014","volume":"136","author":"X Feng","year":"2017","unstructured":"Feng X, Yu W, Li X, Zhou F, Zhang W, Shen Q, Shen P (2017) Apigenin, a modulator of PPAR\u03b3, attenuates HFD-induced NAFLD by regulating hepatocyte lipid metabolism and oxidative stress via Nrf2 activation. Biochem Pharmacol 136:136\u2013149. https:\/\/doi.org\/10.1016\/j.bcp.2017.04.014","journal-title":"Biochem Pharmacol"},{"issue":"1","key":"1587_CR16","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1038\/cr.2010.173","volume":"21","author":"T Gantke","year":"2011","unstructured":"Gantke T, Sriskantharajah S, Ley SC (2011) Regulation and function of TPL-2, an I\u03baB kinase-regulated MAP kinase kinase kinase. Cell Res 21(1):131\u2013145. https:\/\/doi.org\/10.1038\/cr.2010.173","journal-title":"Cell Res"},{"issue":"12","key":"1587_CR17","doi-asserted-by":"publisher","first-page":"3135","DOI":"10.1158\/0008-5472.Can-16-3566","volume":"77","author":"AL Gartel","year":"2017","unstructured":"Gartel AL (2017) FOXM1 in cancer: interactions and vulnerabilities. Cancer Res 77(12):3135\u20133139. https:\/\/doi.org\/10.1158\/0008-5472.Can-16-3566","journal-title":"Cancer Res"},{"key":"1587_CR18","doi-asserted-by":"publisher","DOI":"10.1016\/j.rgmxen.2023.11.001","author":"O G\u00f3mez Escudero","year":"2024","unstructured":"G\u00f3mez Escudero O (2024) Enterocolitis and other immunotherapy and targeted therapy-related gastrointestinal manifestations: a review for gastroenterologist. Rev Gastroenterol Mex (Engl Ed). https:\/\/doi.org\/10.1016\/j.rgmxen.2023.11.001","journal-title":"Rev Gastroenterol Mex (Engl Ed)"},{"issue":"12","key":"1587_CR19","doi-asserted-by":"publisher","first-page":"1631","DOI":"10.1038\/s41590-019-0526-7","volume":"20","author":"T Hasegawa","year":"2019","unstructured":"Hasegawa T, Kikuta J, Sudo T, Matsuura Y, Matsui T, Simmons S, Ishii M (2019) Identification of a novel arthritis-associated osteoclast precursor macrophage regulated by FoxM1. Nat Immunol 20(12):1631\u20131643. https:\/\/doi.org\/10.1038\/s41590-019-0526-7","journal-title":"Nat Immunol"},{"issue":"12","key":"1587_CR20","doi-asserted-by":"publisher","first-page":"593","DOI":"10.1038\/ja.2012.77","volume":"65","author":"NM Haste","year":"2012","unstructured":"Haste NM, Thienphrapa W, Tran DN, Loesgen S, Sun P, Nam SJ, Hensler ME (2012) Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo) 65(12):593\u2013598. https:\/\/doi.org\/10.1038\/ja.2012.77","journal-title":"J Antibiot (Tokyo)"},{"key":"1587_CR21","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21134777","author":"F He","year":"2020","unstructured":"He F, Ru X, Wen T (2020) NRF2, a transcription factor for stress response and beyond. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms21134777","journal-title":"Int J Mol Sci"},{"issue":"12","key":"1587_CR22","doi-asserted-by":"publisher","first-page":"e13330","DOI":"10.1111\/cpr.13330","volume":"55","author":"Y He","year":"2022","unstructured":"He Y, Wu Z, Chen S, Wang J, Zhu L, Xie J, Zou S (2022) Activation of the pattern recognition receptor NOD1 in periodontitis impairs the osteogenic capacity of human periodontal ligament stem cells via p38\/MAPK signalling. Cell Prolif 55(12):e13330. https:\/\/doi.org\/10.1111\/cpr.13330","journal-title":"Cell Prolif"},{"issue":"9","key":"1587_CR23","doi-asserted-by":"publisher","first-page":"725","DOI":"10.1038\/nchem.1114","volume":"3","author":"NS Hegde","year":"2011","unstructured":"Hegde NS, Sanders DA, Rodriguez R, Balasubramanian S (2011) The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nat Chem 3(9):725\u2013731. https:\/\/doi.org\/10.1038\/nchem.1114","journal-title":"Nat Chem"},{"issue":"1","key":"1587_CR24","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/s1369-5274(98)80142-2","volume":"1","author":"D Heumann","year":"1998","unstructured":"Heumann D, Glauser MP, Calandra T (1998) Molecular basis of host-pathogen interaction in septic shock. Curr Opin Microbiol 1(1):49\u201355. https:\/\/doi.org\/10.1016\/s1369-5274(98)80142-2","journal-title":"Curr Opin Microbiol"},{"issue":"2","key":"1587_CR25","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1182\/blood-2010-05-284737","volume":"117","author":"M Hirai","year":"2011","unstructured":"Hirai M, Kadowaki N, Kitawaki T, Fujita H, Takaori-Kondo A, Fukui R, Uchiyama T (2011) Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis. Blood 117(2):500\u2013509. https:\/\/doi.org\/10.1182\/blood-2010-05-284737","journal-title":"Blood"},{"issue":"2","key":"1587_CR26","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1007\/s10637-019-00779-3","volume":"38","author":"YB Hsu","year":"2020","unstructured":"Hsu YB, Lan MC, Kuo YL, Huang CF, Lan MY (2020) A preclinical evaluation of thiostrepton, a natural antibiotic, in nasopharyngeal carcinoma. Invest New Drugs 38(2):264\u2013273. https:\/\/doi.org\/10.1007\/s10637-019-00779-3","journal-title":"Invest New Drugs"},{"issue":"12","key":"1587_CR27","doi-asserted-by":"publisher","first-page":"8184","DOI":"10.1111\/jcmm.14689","volume":"23","author":"TH Huang","year":"2019","unstructured":"Huang TH, Wu ATH, Cheng TS, Lin KT, Lai CJ, Hsieh HW, Chen KY (2019) In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non-small-cell lung cancer. J Cell Mol Med 23(12):8184\u20138195. https:\/\/doi.org\/10.1111\/jcmm.14689","journal-title":"J Cell Mol Med"},{"issue":"1","key":"1587_CR28","doi-asserted-by":"publisher","first-page":"5925","DOI":"10.1038\/s41467-022-33492-6","volume":"13","author":"H Huang","year":"2022","unstructured":"Huang H, Pan W, Wang Y, Kim HS, Shao D, Huang B, Leong KW (2022) Nanoparticulate cell-free DNA scavenger for treating inflammatory bone loss in periodontitis. Nat Commun 13(1):5925. https:\/\/doi.org\/10.1038\/s41467-022-33492-6","journal-title":"Nat Commun"},{"key":"1587_CR29","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202302048","author":"Y Iguchi","year":"2024","unstructured":"Iguchi Y, Takahashi Y, Li J, Araki K, Amakusa Y, Kawakami Y, Katsuno M (2024) I\u03baB kinase phosphorylates cytoplasmic TDP-43 and promotes its proteasome degradation. J Cell Biol. https:\/\/doi.org\/10.1083\/jcb.202302048","journal-title":"J Cell Biol"},{"key":"1587_CR30","unstructured":"Ishii M, Kikuta J, Hasegawa T (2021) Therapeutic agent for arthritis, US2021393734 [P\/OL]"},{"issue":"3","key":"1587_CR31","doi-asserted-by":"publisher","first-page":"323","DOI":"10.2174\/1871520618666180108100211","volume":"19","author":"P Jin","year":"2019","unstructured":"Jin P, Chen X, Yu G, Li Z, Zhang Q, Zhang JV (2019) The clinical and experimental research on the treatment of endometriosis with thiostrepton. Anticancer Agents Med Chem 19(3):323\u2013329. https:\/\/doi.org\/10.2174\/1871520618666180108100211","journal-title":"Anticancer Agents Med Chem"},{"key":"1587_CR32","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24244511","author":"TH Kim","year":"2019","unstructured":"Kim TH, Hanh BTB, Kim G, Lee DG, Park JW, Lee SE, Jang J (2019) Thiostrepton: a novel therapeutic drug candidate for mycobacterium abscessus infection. Molecules. https:\/\/doi.org\/10.3390\/molecules24244511","journal-title":"Molecules"},{"key":"1587_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2021.114718","volume":"192","author":"YS Kwon","year":"2021","unstructured":"Kwon YS, Lee MG, Baek J, Kim NY, Jang H, Kim S (2021) Acyl-CoA synthetase-4 mediates radioresistance of breast cancer cells by regulating FOXM1. Biochem Pharmacol 192:114718. https:\/\/doi.org\/10.1016\/j.bcp.2021.114718","journal-title":"Biochem Pharmacol"},{"issue":"8","key":"1587_CR34","doi-asserted-by":"publisher","first-page":"3912","DOI":"10.4049\/jimmunol.1500194","volume":"195","author":"CY Lai","year":"2015","unstructured":"Lai CY, Yeh DW, Lu CH, Liu YL, Huang LR, Kao CY, Chuang TH (2015) Identification of thiostrepton as a novel inhibitor for psoriasis-like inflammation induced by TLR7\u20139. J Immunol 195(8):3912\u20133921. https:\/\/doi.org\/10.4049\/jimmunol.1500194","journal-title":"J Immunol"},{"key":"1587_CR35","doi-asserted-by":"publisher","first-page":"7807313","DOI":"10.1155\/2017\/7807313","volume":"2017","author":"CY Lai","year":"2017","unstructured":"Lai CY, Su YW, Lin KI, Hsu LC, Chuang TH (2017) Natural modulators of endosomal toll-like receptor-mediated psoriatic skin inflammation. J Immunol Res 2017:7807313. https:\/\/doi.org\/10.1155\/2017\/7807313","journal-title":"J Immunol Res"},{"issue":"616","key":"1587_CR36","doi-asserted-by":"publisher","first-page":"eabj1008","DOI":"10.1126\/scitranslmed.abj1008","volume":"13","author":"LKM Lam","year":"2021","unstructured":"Lam LKM, Murphy S, Kokkinaki D, Venosa A, Sherrill-Mix S, Casu C, Mangalmurti NS (2021) DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia. Sci Transl Med 13(616):eabj1008. https:\/\/doi.org\/10.1126\/scitranslmed.abj1008","journal-title":"Sci Transl Med"},{"issue":"1","key":"1587_CR37","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1002\/path.4829","volume":"241","author":"JK Lau","year":"2017","unstructured":"Lau JK, Zhang X, Yu J (2017) Animal models of non-alcoholic fatty liver disease: current perspectives and recent advances. J Pathol 241(1):36\u201344. https:\/\/doi.org\/10.1002\/path.4829","journal-title":"J Pathol"},{"issue":"1","key":"1587_CR38","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1039\/c0mb00129e","volume":"7","author":"C Li","year":"2011","unstructured":"Li C, Zhang F, Kelly WL (2011) Heterologous production of thiostrepton A and biosynthetic engineering of thiostrepton analogs. Mol Biosyst 7(1):82\u201390. https:\/\/doi.org\/10.1039\/c0mb00129e","journal-title":"Mol Biosyst"},{"key":"1587_CR39","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1016\/j.freeradbiomed.2020.01.184","volume":"152","author":"H Li","year":"2020","unstructured":"Li H, Sun T, Liu C, Cao Y, Liu X (2020) Photobiomodulation (450 nm) alters the infection of periodontitis bacteria via the ROS\/MAPK\/mTOR signaling pathway. Free Radic Biol Med 152:838\u2013853. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2020.01.184","journal-title":"Free Radic Biol Med"},{"key":"1587_CR40","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12071363","author":"J Li","year":"2023","unstructured":"Li J, Arest S, Olszowy B, Gordon J, Barrero CA, Perez-Leal O (2023) CRISPR\/Cas9-based screening of FDA-approved drugs for NRF2 activation: a novel approach to discover therapeutics for non-alcoholic fatty liver disease. Antioxidants (Basel). https:\/\/doi.org\/10.3390\/antiox12071363","journal-title":"Antioxidants (Basel)"},{"issue":"9","key":"1587_CR41","doi-asserted-by":"publisher","first-page":"8551","DOI":"10.1021\/acsnano.3c00906","volume":"17","author":"Z Li","year":"2023","unstructured":"Li Z, Feng Y, Zhang S, Li T, Li H, Wang D, Chen X (2023) A multifunctional nanoparticle mitigating cytokine storm by scavenging multiple inflammatory mediators of Sepsis. ACS Nano 17(9):8551\u20138563. https:\/\/doi.org\/10.1021\/acsnano.3c00906","journal-title":"ACS Nano"},{"issue":"Pt 1","key":"1587_CR42","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1016\/j.freeradbiomed.2022.09.018","volume":"193","author":"SX Liu","year":"2022","unstructured":"Liu SX, Zhou Y, Zhao L, Zhou LS, Sun J, Liu GJ, Zhou YN (2022) Thiostrepton confers protection against reactive oxygen species-related apoptosis by restraining FOXM1-triggerred development of gastric cancer. Free Radic Biol Med 193(Pt 1):385\u2013404. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2022.09.018","journal-title":"Free Radic Biol Med"},{"key":"1587_CR43","doi-asserted-by":"publisher","first-page":"102570","DOI":"10.1016\/j.redox.2022.102570","volume":"59","author":"P Liu","year":"2023","unstructured":"Liu P, Anandhan A, Chen J, Shakya A, Dodson M, Ooi A, Zhang DD (2023) Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease. Redox Biol 59:102570. https:\/\/doi.org\/10.1016\/j.redox.2022.102570","journal-title":"Redox Biol"},{"key":"1587_CR44","doi-asserted-by":"publisher","first-page":"106583","DOI":"10.1016\/j.oraloncology.2023.106583","volume":"147","author":"ZQ Liu","year":"2023","unstructured":"Liu ZQ, Zhao YN, Wu YS, Zhang BY, Chen EN, Peng QH, OuYang PY (2023) Immunochemotherapy alone or immunochemotherapy plus subsequent locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma. Oral Oncol 147:106583. https:\/\/doi.org\/10.1016\/j.oraloncology.2023.106583","journal-title":"Oral Oncol"},{"key":"1587_CR45","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2024.02.003","author":"J Liu","year":"2024","unstructured":"Liu J, Kang R, Tang D (2024) Lipopolysaccharide delivery systems in innate immunity. Trends Immunol. https:\/\/doi.org\/10.1016\/j.it.2024.02.003","journal-title":"Trends Immunol"},{"issue":"5","key":"1587_CR46","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.tube.2009.07.002","volume":"89","author":"KE Lougheed","year":"2009","unstructured":"Lougheed KE, Taylor DL, Osborne SA, Bryans JS, Buxton RS (2009) New anti-tuberculosis agents amongst known drugs. Tuberculosis (Edinb) 89(5):364\u2013370. https:\/\/doi.org\/10.1016\/j.tube.2009.07.002","journal-title":"Tuberculosis (Edinb)"},{"issue":"11","key":"1587_CR47","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1038\/s41423-023-01085-y","volume":"20","author":"Y Luo","year":"2023","unstructured":"Luo Y, Liu C, Luo Y, Zhang X, Li J, Hu C, Yang S (2023) Thiostrepton alleviates experimental colitis by promoting ROR\u03b3t ubiquitination and modulating dysbiosis. Cell Mol Immunol 20(11):1352\u20131366. https:\/\/doi.org\/10.1038\/s41423-023-01085-y","journal-title":"Cell Mol Immunol"},{"key":"1587_CR48","doi-asserted-by":"publisher","DOI":"10.1007\/s40615-024-01968-4","author":"KN Ly","year":"2024","unstructured":"Ly KN, Yin S, Spradling PR (2024) Disparities in social vulnerability and premature mortality among decedents with hepatitis B, United States, 2010\u20132019. J Racial Ethn Health Disparities. https:\/\/doi.org\/10.1007\/s40615-024-01968-4","journal-title":"J Racial Ethn Health Disparities"},{"key":"1587_CR49","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112094","volume":"133","author":"J Lyu","year":"2024","unstructured":"Lyu J, Shen S, Hao Y, Zhou M, Tao J (2024) The impact of Thiopeptide antibiotics on inflammatory responses in periodontal tissues through the regulation of the MAPK pathway. Int Immunopharmacol 133:112094. https:\/\/doi.org\/10.1016\/j.intimp.2024.112094","journal-title":"Int Immunopharmacol"},{"issue":"1","key":"1587_CR50","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1159\/000531397","volume":"31","author":"MV Machado","year":"2024","unstructured":"Machado MV (2024) The growing landscape of NAFLD-associated hepatocellular carcinoma and its impact in surveillance. GE Port J Gastroenterol 31(1):14\u201323. https:\/\/doi.org\/10.1159\/000531397","journal-title":"GE Port J Gastroenterol"},{"issue":"2","key":"1587_CR51","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s11154-020-09621-1","volume":"22","author":"S Maier","year":"2021","unstructured":"Maier S, Wieland A, Cree-Green M, Nadeau K, Sullivan S, Lanaspa MA, Jensen T (2021) Lean NAFLD: an underrecognized and challenging disorder in medicine. Rev Endocr Metab Disord 22(2):351\u2013366. https:\/\/doi.org\/10.1007\/s11154-020-09621-1","journal-title":"Rev Endocr Metab Disord"},{"key":"1587_CR52","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.bbi.2012.10.014","volume":"28","author":"T Maslanik","year":"2013","unstructured":"Maslanik T, Mahaffey L, Tannura K, Beninson L, Greenwood BN, Fleshner M (2013) The inflammasome and danger associated molecular patterns (DAMPs) are implicated in cytokine and chemokine responses following stressor exposure. Brain Behav Immun 28:54\u201362. https:\/\/doi.org\/10.1016\/j.bbi.2012.10.014","journal-title":"Brain Behav Immun"},{"issue":"6","key":"1587_CR53","doi-asserted-by":"publisher","first-page":"771","DOI":"10.1016\/j.cell.2010.03.006","volume":"140","author":"R Medzhitov","year":"2010","unstructured":"Medzhitov R (2010) Inflammation 2010: new adventures of an old flame. Cell 140(6):771\u2013776. https:\/\/doi.org\/10.1016\/j.cell.2010.03.006","journal-title":"Cell"},{"issue":"10","key":"1587_CR54","doi-asserted-by":"publisher","first-page":"1984","DOI":"10.1016\/j.ajpath.2020.07.010","volume":"190","author":"ME Mickael","year":"2020","unstructured":"Mickael ME, Bhaumik S, Basu R (2020) Retinoid-related orphan receptor ROR\u03b3t in CD4(+) T-cell-mediated intestinal homeostasis and inflammation. Am J Pathol 190(10):1984\u20131999. https:\/\/doi.org\/10.1016\/j.ajpath.2020.07.010","journal-title":"Am J Pathol"},{"issue":"18","key":"1587_CR55","doi-asserted-by":"publisher","first-page":"7992","DOI":"10.1021\/ja00071a009","volume":"115","author":"U Mocek","year":"1993","unstructured":"Mocek U, Zeng Z, O\u2019Hagan D, Zhou P, Fan LDG, Beale JM, Floss HG (1993) Biosynthesis of the modified peptide antibiotic thiostrepton in Streptomyces azureus and Streptomyces laurentii. J Am Chem Soc 115(18):7992\u20138001. https:\/\/doi.org\/10.1021\/ja00071a009","journal-title":"J Am Chem Soc"},{"key":"1587_CR56","unstructured":"Muir LA, Barreto A (1977) Control of lactic acidosis in ruminants, US4061732 [P\/OL]"},{"key":"1587_CR57","doi-asserted-by":"publisher","DOI":"10.1111\/bph.16246","author":"S Murakami","year":"2023","unstructured":"Murakami S, Kusano Y, Okazaki K, Akaike T, Motohashi H (2023) NRF2 signalling in cytoprotection and metabolism. Br J Pharmacol. https:\/\/doi.org\/10.1111\/bph.16246","journal-title":"Br J Pharmacol"},{"key":"1587_CR58","doi-asserted-by":"publisher","DOI":"10.3390\/biom12060824","author":"F Nassir","year":"2022","unstructured":"Nassir F (2022) NAFLD: mechanisms, treatments, and biomarkers. Biomolecules. https:\/\/doi.org\/10.3390\/biom12060824","journal-title":"Biomolecules"},{"issue":"50","key":"1587_CR59","doi-asserted-by":"publisher","first-page":"12414","DOI":"10.1002\/anie.201205576","volume":"51","author":"KC Nicolaou","year":"2012","unstructured":"Nicolaou KC (2012) How thiostrepton was made in the laboratory. Angew Chem Int Ed Engl 51(50):12414\u201312436. https:\/\/doi.org\/10.1002\/anie.201205576","journal-title":"Angew Chem Int Ed Engl"},{"issue":"2","key":"1587_CR60","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0017110","volume":"6","author":"B Pandit","year":"2011","unstructured":"Pandit B, Gartel AL (2011) Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells. PLoS ONE 6(2):e17110. https:\/\/doi.org\/10.1371\/journal.pone.0017110","journal-title":"PLoS ONE"},{"key":"1587_CR61","doi-asserted-by":"publisher","DOI":"10.1128\/aac.02328-19","author":"W Peng","year":"2020","unstructured":"Peng W, Hong Z, Chen X, Gao H, Dai Z, Zhao J, Deng K (2020) Thiostrepton reactivates latent HIV-1 through the p-TEFb and NF-\u03baB pathways mediated by heat shock response. Antimicrob Agents Chemother. https:\/\/doi.org\/10.1128\/aac.02328-19","journal-title":"Antimicrob Agents Chemother"},{"issue":"3","key":"1587_CR62","doi-asserted-by":"publisher","first-page":"394","DOI":"10.1016\/j.bcp.2005.04.030","volume":"70","author":"RF Place","year":"2005","unstructured":"Place RF, Noonan EJ, Giardina C (2005) HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha. Biochem Pharmacol 70(3):394\u2013406. https:\/\/doi.org\/10.1016\/j.bcp.2005.04.030","journal-title":"Biochem Pharmacol"},{"issue":"7","key":"1587_CR63","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1016\/0968-0896(96)00126-5","volume":"4","author":"ND Priestley","year":"1996","unstructured":"Priestley ND, Smith TM, Shipley PR, Floss HG (1996) Studies on the biosynthesis of thiostrepton: 4-(1-hydroxyethyl)quinoline-2-carboxylate as a free intermediate on the pathway to the quinaldic acid moiety. Bioorg Med Chem 4(7):1135\u20131147. https:\/\/doi.org\/10.1016\/0968-0896(96)00126-5","journal-title":"Bioorg Med Chem"},{"key":"1587_CR64","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20061475","author":"A Rendon","year":"2019","unstructured":"Rendon A, Sch\u00e4kel K (2019) Psoriasis pathogenesis and treatment. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms20061475","journal-title":"Int J Mol Sci"},{"key":"1587_CR65","doi-asserted-by":"publisher","DOI":"10.3390\/cells10010110","author":"A Reza","year":"2021","unstructured":"Reza A, Yuan YG (2021) MicroRNAs mediated regulation of the ribosomal proteins and its consequences on the global translation of proteins. Cells. https:\/\/doi.org\/10.3390\/cells10010110","journal-title":"Cells"},{"issue":"2","key":"1587_CR66","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1089\/apc.2007.0034","volume":"22","author":"DJ Riedel","year":"2008","unstructured":"Riedel DJ, Gebo KA, Moore RD, Lucas GM (2008) A ten-year analysis of the incidence and risk factors for acute pancreatitis requiring hospitalization in an urban HIV clinical cohort. AIDS Patient Care STDS 22(2):113\u2013121. https:\/\/doi.org\/10.1089\/apc.2007.0034","journal-title":"AIDS Patient Care STDS"},{"issue":"8","key":"1587_CR67","first-page":"815","volume":"3","author":"MJ Rogers","year":"1997","unstructured":"Rogers MJ, Bukhman YV, McCutchan TF, Draper DE (1997) Interaction of thiostrepton with an RNA fragment derived from the plastid-encoded ribosomal RNA of the malaria parasite. RNA 3(8):815\u2013820","journal-title":"RNA"},{"key":"1587_CR68","doi-asserted-by":"publisher","first-page":"154561","DOI":"10.1016\/j.phymed.2022.154561","volume":"109","author":"B Shen","year":"2023","unstructured":"Shen B, Wang Y, Cheng J, Peng Y, Zhang Q, Li Z, Feng H (2023) Pterostilbene alleviated NAFLD via AMPK\/mTOR signaling pathways and autophagy by promoting Nrf2. Phytomedicine 109:154561. https:\/\/doi.org\/10.1016\/j.phymed.2022.154561","journal-title":"Phytomedicine"},{"key":"1587_CR69","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2022.140400","volume":"454","author":"M Shin","year":"2023","unstructured":"Shin M, Choi YE, Yan L, Goh S-H, Choi Y (2023) FOXM1 inhibitor-loaded nanoliposomes for enhanced immunotherapy against cancer. Chem Eng J 454:140400. https:\/\/doi.org\/10.1016\/j.cej.2022.140400","journal-title":"Chem Eng J"},{"key":"1587_CR70","unstructured":"Shoichi S, Tsuneo Y, Takahiro S (1988) Production of Thiostrepton, JP63000296 [P\/OL]"},{"issue":"2","key":"1587_CR71","doi-asserted-by":"publisher","first-page":"455","DOI":"10.1128\/jb.142.2.455-461.1980","volume":"142","author":"J Thompson","year":"1980","unstructured":"Thompson J, Cundliffe E (1980) Resistance to thiostrepton, siomycin, and sporangiomycin in actinomycetes that produce them. J Bacteriol 142(2):455\u2013461. https:\/\/doi.org\/10.1128\/jb.142.2.455-461.1980","journal-title":"J Bacteriol"},{"key":"1587_CR72","doi-asserted-by":"publisher","first-page":"10888","DOI":"10.1038\/ncomms10888","volume":"7","author":"MJ Tosiek","year":"2016","unstructured":"Tosiek MJ, Fiette L, El Daker S, Eberl G, Freitas AA (2016) IL-15-dependent balance between Foxp3 and ROR\u03b3t expression impacts inflammatory bowel disease. Nat Commun 7:10888. https:\/\/doi.org\/10.1038\/ncomms10888","journal-title":"Nat Commun"},{"key":"1587_CR73","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25042077","author":"D V\u0103lean","year":"2024","unstructured":"V\u0103lean D, Zaharie R, \u021aaulean R, Usatiuc L, Zaharie F (2024) Recent trends in non-invasive methods of diagnosis and evaluation of inflammatory bowel disease: a short review. Int J Mol Sci. https:\/\/doi.org\/10.3390\/ijms25042077","journal-title":"Int J Mol Sci"},{"issue":"1","key":"1587_CR74","doi-asserted-by":"publisher","first-page":"360","DOI":"10.1093\/nar\/gkr623","volume":"40","author":"JD Walter","year":"2012","unstructured":"Walter JD, Hunter M, Cobb M, Traeger G, Spiegel PC (2012) Thiostrepton inhibits stable 70S ribosome binding and ribosome-dependent GTPase activation of elongation factor G and elongation factor 4. Nucleic Acids Res 40(1):360\u2013370. https:\/\/doi.org\/10.1093\/nar\/gkr623","journal-title":"Nucleic Acids Res"},{"issue":"12","key":"1587_CR75","doi-asserted-by":"publisher","first-page":"2287","DOI":"10.1158\/1535-7163.Mct-11-0536","volume":"10","author":"M Wang","year":"2011","unstructured":"Wang M, Gartel AL (2011) Micelle-encapsulated thiostrepton as an effective nanomedicine for inhibiting tumor growth and for suppressing FOXM1 in human xenografts. Mol Cancer Ther 10(12):2287\u20132297. https:\/\/doi.org\/10.1158\/1535-7163.Mct-11-0536","journal-title":"Mol Cancer Ther"},{"issue":"3","key":"1587_CR76","doi-asserted-by":"publisher","first-page":"184","DOI":"10.4161\/cbt.13.3.18875","volume":"13","author":"M Wang","year":"2012","unstructured":"Wang M, Gartel AL (2012) Combination with bortezomib enhances the antitumor effects of nanoparticle-encapsulated thiostrepton. Cancer Biol Ther 13(3):184\u2013189. https:\/\/doi.org\/10.4161\/cbt.13.3.18875","journal-title":"Cancer Biol Ther"},{"key":"1587_CR77","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2019-000462","author":"Y Wang","year":"2020","unstructured":"Wang Y, Xie W, Humeau J, Chen G, Liu P, Pol J, Kroemer G (2020) Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy. J Immunother Cancer. https:\/\/doi.org\/10.1136\/jitc-2019-000462","journal-title":"J Immunother Cancer"},{"issue":"6","key":"1587_CR78","doi-asserted-by":"publisher","first-page":"2508","DOI":"10.1016\/j.xphs.2021.01.018","volume":"110","author":"S Wongkhieo","year":"2021","unstructured":"Wongkhieo S, Numdee K, Lam EWF, Choowongkomon K, Kongsema M, Khongkow M (2021) Liposomal thiostrepton formulation and its effect on breast cancer growth inhibition. J Pharm Sci 110(6):2508\u20132516. https:\/\/doi.org\/10.1016\/j.xphs.2021.01.018","journal-title":"J Pharm Sci"},{"key":"1587_CR79","doi-asserted-by":"publisher","first-page":"274","DOI":"10.1016\/j.biopha.2018.05.135","volume":"105","author":"C Yan","year":"2018","unstructured":"Yan C, Zhang Y, Zhang X, Aa J, Wang G, Xie Y (2018) Curcumin regulates endogenous and exogenous metabolism via Nrf2-FXR-LXR pathway in NAFLD mice. Biomed Pharmacother 105:274\u2013281. https:\/\/doi.org\/10.1016\/j.biopha.2018.05.135","journal-title":"Biomed Pharmacother"},{"key":"1587_CR80","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.116911","volume":"176","author":"I Yang","year":"2024","unstructured":"Yang I, Jeong NH, Choi YA, Kwon TK, Lee S, Khang D, Kim SH (2024) Monotropein mitigates atopic dermatitis-like skin inflammation through JAK\/STAT signaling pathway inhibition. Biomed Pharmacother 176:116911. https:\/\/doi.org\/10.1016\/j.biopha.2024.116911","journal-title":"Biomed Pharmacother"},{"issue":"7","key":"1587_CR81","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1038\/s41419-022-05082-3","volume":"13","author":"W Zhang","year":"2022","unstructured":"Zhang W, Gong M, Zhang W, Mo J, Zhang S, Zhu Z, Wang Z (2022) Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3\/GPX4 signalling. Cell Death Dis 13(7):630. https:\/\/doi.org\/10.1038\/s41419-022-05082-3","journal-title":"Cell Death Dis"},{"key":"1587_CR82","doi-asserted-by":"publisher","first-page":"1338918","DOI":"10.3389\/fimmu.2023.1338918","volume":"14","author":"H Zhang","year":"2023","unstructured":"Zhang H, Shi Y, Lin C, He C, Wang S, Li Q, Li M (2023) Overcoming cancer risk in inflammatory bowel disease: new insights into preventive strategies and pathogenesis mechanisms including interactions of immune cells, cancer signaling pathways, and gut microbiota. Front Immunol 14:1338918. https:\/\/doi.org\/10.3389\/fimmu.2023.1338918","journal-title":"Front Immunol"},{"issue":"9","key":"1587_CR83","doi-asserted-by":"publisher","first-page":"6171","DOI":"10.1021\/acs.est.1c00515","volume":"55","author":"H Zhao","year":"2021","unstructured":"Zhao H, Wang Y, Liu Y, Yin K, Wang D, Li B, Xing M (2021) ROS-induced hepatotoxicity under cypermethrin: involvement of the crosstalk between Nrf2\/Keap1 and NF-\u03baB\/i\u03baB-\u03b1 pathways regulated by proteasome. Environ Sci Technol 55(9):6171\u20136183. https:\/\/doi.org\/10.1021\/acs.est.1c00515","journal-title":"Environ Sci Technol"},{"issue":"50","key":"1587_CR84","doi-asserted-by":"publisher","first-page":"14318","DOI":"10.1073\/pnas.1612607113","volume":"113","author":"Q Zheng","year":"2016","unstructured":"Zheng Q, Wang S, Duan P, Liao R, Chen D, Liu W (2016) An \u03b1\/\u03b2-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening\/macrocyclization. Proc Natl Acad Sci USA 113(50):14318\u201314323. https:\/\/doi.org\/10.1073\/pnas.1612607113","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"1587_CR85","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1186\/s13046-019-1504-5","volume":"39","author":"S Zheng","year":"2020","unstructured":"Zheng S, Zhou C, Wang Y, Li H, Sun Y, Shen Z (2020) TRIM6 promotes colorectal cancer cells proliferation and response to thiostrepton by TIS21\/FoxM1. J Exp Clin Cancer Res 39(1):23. https:\/\/doi.org\/10.1186\/s13046-019-1504-5","journal-title":"J Exp Clin Cancer Res"},{"issue":"1","key":"1587_CR86","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s12902-024-01562-z","volume":"24","author":"C Zheng","year":"2024","unstructured":"Zheng C, Zheng Y, Zheng Z (2024) Therapeutic plasma exchange decreases serum triglyceride level rapidly and reduces early recurrence rate but no advantages in improving outcomes for patients with hyperlipidemic acute pancreatitis: a retrospective propensity score matching analysis based on twenty year\u2019s experience. BMC Endocr Disord 24(1):32. https:\/\/doi.org\/10.1186\/s12902-024-01562-z","journal-title":"BMC Endocr Disord"},{"issue":"18","key":"1587_CR87","doi-asserted-by":"publisher","first-page":"7274","DOI":"10.1021\/ja00200a065","volume":"111","author":"P Zhou","year":"1989","unstructured":"Zhou P, O\u2019Hagan D, Mocek U, Zeng Z, Yuen LD, Frenzel T, Floss HG (1989) Biosynthesis of the antibiotic thiostrepton. Methylation of tryptophan in the formation of the quinaldic acid moiety by transfer of the methionine methyl group with net retention of configuration. J Am Chem Soci 111(18):7274\u20137276. https:\/\/doi.org\/10.1021\/ja00200a065","journal-title":"J Am Chem Soci"},{"issue":"9","key":"1587_CR88","doi-asserted-by":"publisher","first-page":"e107181","DOI":"10.1371\/journal.pone.0107181","volume":"9","author":"J Zhou","year":"2014","unstructured":"Zhou J, Qian C, Zhao M, Yu X, Kang Y, Ma X, Du B (2014) Epidemiology and outcome of severe sepsis and septic shock in intensive care units in mainland China. PLoS One 9(9):e107181. https:\/\/doi.org\/10.1371\/journal.pone.0107181","journal-title":"PLoS One"},{"issue":"1","key":"1587_CR89","doi-asserted-by":"publisher","first-page":"e12957","DOI":"10.1111\/cpr.12957","volume":"54","author":"M Zhou","year":"2021","unstructured":"Zhou M, Hu H, Han Y, Li J, Zhang Y, Tang S, Zhang X (2021) Long non-coding RNA 01126 promotes periodontitis pathogenesis of human periodontal ligament cells via miR-518a-5p\/HIF-1\u03b1\/MAPK pathway. Cell Prolif 54(1):e12957. https:\/\/doi.org\/10.1111\/cpr.12957","journal-title":"Cell Prolif"},{"issue":"7","key":"1587_CR90","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1177\/0960327120984225","volume":"40","author":"M Zhou","year":"2021","unstructured":"Zhou M, Shi J, Lan S, Gong X (2021b) FOXM1 regulates the proliferation, apoptosis and inflammatory response of keratinocytes through the NF-\u03baB signaling pathway. Hum Exp Toxicol 40(7):1130\u20131140. https:\/\/doi.org\/10.1177\/0960327120984225","journal-title":"Hum Exp Toxicol"},{"key":"1587_CR91","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.826204","volume":"10","author":"J Zhou","year":"2022","unstructured":"Zhou J, Zheng Q, Chen Z (2022) The Nrf2 pathway in liver diseases. Front Cell Dev Biol 10:826204. https:\/\/doi.org\/10.3389\/fcell.2022.826204","journal-title":"Front Cell Dev Biol"},{"key":"1587_CR92","doi-asserted-by":"publisher","first-page":"1678","DOI":"10.1016\/j.biopha.2018.04.192","volume":"103","author":"D Zhu-Ge","year":"2018","unstructured":"Zhu-Ge D, Yang YP, Jiang ZJ (2018) Knockdown CRNDE alleviates LPS-induced inflammation injury via FOXM1 in WI-38 cells. Biomed Pharmacother 103:1678\u20131687. https:\/\/doi.org\/10.1016\/j.biopha.2018.04.192","journal-title":"Biomed Pharmacother"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-024-01587-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-024-01587-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-024-01587-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,5]],"date-time":"2025-02-05T04:30:54Z","timestamp":1738729854000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-024-01587-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,2]]},"references-count":92,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["1587"],"URL":"https:\/\/doi.org\/10.1007\/s10787-024-01587-9","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,2]]},"assertion":[{"value":"2 August 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 October 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 November 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors disclosed no relevant relationships.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}