{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T01:05:41Z","timestamp":1791335141835,"version":"4.3.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1007\/s10787-025-01736-8","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T10:48:45Z","timestamp":1746614925000},"page":"2721-2736","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Amelioration of pain and adjuvant-induced arthritis by syringic acid via modulation of behavioral parameters and inflammatory mediators i.e. TNF-\u03b1, Interleukins, MCP-1, NF-kB and COX-2"],"prefix":"10.1007","volume":"33","author":[{"given":"Noviara","family":"Saleem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Atif","family":"Raza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4775-7337","authenticated-orcid":false,"family":"Alamgeer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Khalil-ur-Rehman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rukhsana","family":"Anwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abrar","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hafiz Muhammad","family":"Irfan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"issue":"9","key":"1736_CR1","doi-asserted-by":"publisher","first-page":"1110","DOI":"10.3109\/13880209.2013.781194","volume":"51","author":"M-S Abaza","year":"2013","unstructured":"Abaza M-S, Al-Attiyah RA, Bhardwaj R, Abbadi G, Koyippally M, Afzal M (2013) Syringic acid from Tamarix aucheriana possesses antimitogenic and chemo-sensitizing activities in human colorectal cancer cells. Pharm Biol 51(9):1110\u20131124","journal-title":"Pharm Biol"},{"key":"1736_CR2","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-017-1879-9","volume":"17","author":"Alamgeer","year":"2017","unstructured":"Alamgeer, Uttra AM, Hasan UH (2017) Anti-arthritic activity of aqueous-methanolic extract and various fractions of Berberis orthobotrys Bien ex Aitch. BMC Complement Altern Med 17:1\u201316","journal-title":"BMC Complement Altern Med"},{"issue":"3","key":"1736_CR3","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1080\/13510002.2017.1297885","volume":"22","author":"N Al-Waili","year":"2017","unstructured":"Al-Waili N, Al-Waili H, Al-Waili T, Salom K (2017) Natural antioxidants in the treatment and prevention of diabetic nephropathy; a potential approach that warrants clinical trials. Redox Rep 22(3):99\u2013118","journal-title":"Redox Rep"},{"issue":"1","key":"1736_CR4","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/S2666-5247(21)00275-5","volume":"3","author":"A Angyal","year":"2022","unstructured":"Angyal A, Longet S, Moore SC, Payne RP, Harding A, Tipton T, Meardon N (2022) T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study. Lancet Microb 3(1):21\u201331","journal-title":"Lancet Microb"},{"key":"1736_CR5","doi-asserted-by":"publisher","first-page":"659","DOI":"10.3389\/fphar.2019.00659","volume":"10","author":"A Balkrishna","year":"2019","unstructured":"Balkrishna A, Sakat SS, Joshi K, Paudel S, Joshi D, Joshi K, Varshney A (2019) Anti-inflammatory and anti-arthritic efficacies of an Indian traditional herbo-mineral medicine \u201cDivya Amvatari Ras\u201d in collagen antibody-induced arthritis (CAIA) mouse model through modulation of IL-6\/IL-1\u03b2\/TNF-\u03b1\/nf\u03bab signaling. Front Pharmacol 10:659","journal-title":"Front Pharmacol"},{"issue":"2","key":"1736_CR6","first-page":"71","volume":"11","author":"S Chanda","year":"2019","unstructured":"Chanda S, Juvekar A (2019) In vitro anti-inflammatory activity of syringic acid. Int J Pharm Pharm Sci 11(2):71\u201373","journal-title":"Int J Pharm Pharm Sci"},{"key":"1736_CR7","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1016\/j.intimp.2018.04.001","volume":"59","author":"J Chu","year":"2018","unstructured":"Chu J, Wang X, Bi H, Li L, Ren M, Wang J (2018) Dihydromyricetin relieves rheumatoid arthritis symptoms and suppresses expression of pro-inflammatory cytokines via the activation of Nrf2 pathway in rheumatoid arthritis model. Int Immunopharmacol 59:174\u2013180","journal-title":"Int Immunopharmacol"},{"issue":"3","key":"1736_CR8","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.jtcme.2020.04.006","volume":"11","author":"C Das","year":"2021","unstructured":"Das C, Bose A, Das D (2021) Ayurvedic Balarista ameliorate anti-arthritic activity in adjuvant induced arthritic rats by inhibiting pro-inflammatory cytokines and oxidative stress. J Tradit Complement Med 11(3):228\u2013237","journal-title":"J Tradit Complement Med"},{"issue":"1","key":"1736_CR9","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1472-6882-10-56","volume":"10","author":"S Ekambaram","year":"2010","unstructured":"Ekambaram S, Perumal SS, Subramanian V (2010) Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund\u2019s adjuvant induced arthritic rat model. BMC Complement Altern Med 10(1):56. https:\/\/doi.org\/10.1186\/1472-6882-10-56","journal-title":"BMC Complement Altern Med"},{"key":"1736_CR10","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/4943965","author":"F Forouzanfar","year":"2022","unstructured":"Forouzanfar F, Pourbagher-Shahri AM, Ghazavi H (2022) Evaluation of antiarthritic and antinociceptive effects of cedrol in a rat model of arthritis. Oxidative Med Cell Longev. https:\/\/doi.org\/10.1155\/2022\/4943965","journal-title":"Oxidative Med Cell Longev"},{"key":"1736_CR11","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1007\/978-3-662-43492-5_8","volume-title":"Interleukin-10 in health and disease","author":"L Gabry\u0161ov\u00e1","year":"2014","unstructured":"Gabry\u0161ov\u00e1 L, Howes A, Saraiva M, O\u2019Garra AG (2014) The regulation of IL-10 expression. Interleukin-10 in health and disease. Springer, Berlin, pp 157\u2013190"},{"key":"1736_CR12","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1007\/s10787-020-00757-9","volume":"28","author":"G George","year":"2020","unstructured":"George G, Shyni G, Raghu K (2020) Current and novel therapeutic targets in the treatment of rheumatoid arthritis. Inflammopharmacol 28:1457\u20131476","journal-title":"Inflammopharmacol"},{"key":"1736_CR13","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1007\/s10787-017-0370-z","volume":"26","author":"P Gohil","year":"2018","unstructured":"Gohil P, Patel V, Deshpande S, Chorawala M, Shah G (2018) Anti-arthritic activity of cell wall content of Lactobacillus plantarum in freund\u2019s adjuvant-induced arthritic rats: involvement of cellular inflammatory mediators and other biomarkers. Inflammopharmacol 26:171\u2013181","journal-title":"Inflammopharmacol"},{"key":"1736_CR14","first-page":"45","volume":"77","author":"AM-NM Greanious","year":"2021","unstructured":"Greanious AM-NM, Ncube N, Sibanda A, Dube D, Farai FC, Makoni P (2021) Phytotherapeutics attenuation of oxidative stress, inflammation and lipid peroxidation in severe and chronic diseases. Accent Lipid Perox 77:45","journal-title":"Accent Lipid Perox"},{"issue":"8","key":"1736_CR15","doi-asserted-by":"publisher","first-page":"1170","DOI":"10.1038\/s41430-020-00845-7","volume":"75","author":"BJ Grech","year":"2021","unstructured":"Grech BJ (2021) Mechanistic insights into the treatment of iron-deficiency anemia and arthritis in humans with dietary molybdenum. Eur J Clin Nutr 75(8):1170\u20131175","journal-title":"Eur J Clin Nutr"},{"key":"1736_CR16","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1007\/s10787-023-01185-1","volume":"5","author":"B Gul","year":"2023","unstructured":"Gul B, Anwar R, Saleem M, Noor A, Ullah MI (2023) Cassia absus-mediated upregulation of IL-4, IL-10 and downregulation of IL-1\u03b2, IL-6, TNF-\u03b1, NF-\u03baB IFN-\u03b3 in CFA-induced arthritis model. Inflammopharmacol 5:5. https:\/\/doi.org\/10.1007\/s10787-023-01185-1","journal-title":"Inflammopharmacol"},{"key":"1736_CR17","doi-asserted-by":"publisher","first-page":"104615","DOI":"10.1016\/j.jddst.2023.104615","volume":"85","author":"S Ijaz","year":"2023","unstructured":"Ijaz S, Shamim R, Sultana M, Raza SA, Shafique S, Kanwal U (2023) Doxorubicin loaded zinc oxide nanoflowers\u2013Surmounting drug-induced toxicity. J Drug Deliv Sci Technol 85:104615","journal-title":"J Drug Deliv Sci Technol"},{"key":"1736_CR18","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s10787-011-0090-8","volume":"19","author":"S Kaur","year":"2011","unstructured":"Kaur S, Bijjem KRV, Sharma PL (2011) Anti-inflammatory and antihyperalgesic effects of the combination of ibuprofen and hemin in adjuvant-induced arthritis in the Wistar rat. Inflammopharmacol 19:265\u2013272","journal-title":"Inflammopharmacol"},{"issue":"10","key":"1736_CR19","first-page":"71","volume":"7","author":"A Keegan","year":"2021","unstructured":"Keegan A, Leonard W, Zhu J (2021) Recent advances in understanding the role of IL-4 signaling. Fac Rev 7(10):71","journal-title":"Fac Rev"},{"key":"1736_CR20","doi-asserted-by":"publisher","first-page":"1175","DOI":"10.1007\/s00210-012-0802-7","volume":"385","author":"S Kumar","year":"2012","unstructured":"Kumar S, Prahalathan P, Raja B (2012) Syringic acid ameliorates L-NAME-induced hypertension by reducing oxidative stress. Naunyn Schmiedebergs Arch Pharmacol 385:1175\u20131184","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"2","key":"1736_CR21","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1002\/ddr.21487","volume":"80","author":"Y Li","year":"2019","unstructured":"Li Y, Zhang L, Wang X, Wu W, Qin R (2019) Effect of Syringic acid on antioxidant biomarkers and associated inflammatory markers in mice model of asthma. Drug Dev Res 80(2):253\u2013261","journal-title":"Drug Dev Res"},{"issue":"9","key":"1736_CR22","first-page":"999","volume":"41","author":"S-G Lv","year":"2021","unstructured":"Lv S-G, Liu H, Du J, Ruan C, Zhang W-B, Feng P-P (2021) Effect of Bo\u2019s abdominal acupuncture as adjunctive therapy on rheumatoid arthritis and ESR RF and CRP levels. CAM 41(9):999\u20131002","journal-title":"CAM"},{"key":"1736_CR23","doi-asserted-by":"crossref","unstructured":"Mahdi RK, Al-Hassnawi ATS, AL-Rubaei HM (2019) Biochemical investigation effect of Vespa orientalis venom therapy: rat rheumatoid arthritis model. In: Paper presented at the AIP Conference Proceedings","DOI":"10.1063\/1.5123105"},{"issue":"5","key":"1736_CR24","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.1007\/s10787-021-00849-0","volume":"29","author":"MH Mahnashi","year":"2021","unstructured":"Mahnashi MH, Jabbar Z, Irfan HM, Asim MH, Akram M, Saif A, Asiri SA (2021) Venlafaxine demonstrated anti-arthritic activity possibly through down regulation of TNF-\u03b1, IL-6, IL-1\u03b2, and COX-2. Inflammopharmacol 29(5):1413\u20131425","journal-title":"Inflammopharmacol"},{"issue":"5\u20136","key":"1736_CR25","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1177\/1759720X18776224","volume":"10","author":"CJ Malemud","year":"2018","unstructured":"Malemud CJ (2018) The role of the JAK\/STAT signal pathway in rheumatoid arthritis. Ther Adv Musculoskelet Dis 10(5\u20136):117\u2013127","journal-title":"Ther Adv Musculoskelet Dis"},{"key":"1736_CR26","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1002\/cbf.3813","volume":"41","author":"HUH Mansoor","year":"2023","unstructured":"Mansoor HUH, Ahmed A, Rasool F (2023) The inhibitory potential of chemical constituents of Ficus carica targeting interleukin-6 (IL-6) mediated inflammation. Cell Biochem Funct 41:573","journal-title":"Cell Biochem Funct"},{"issue":"2","key":"1736_CR27","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.jbspin.2010.05.017","volume":"78","author":"C Masson","year":"2011","unstructured":"Masson C (2011) Rheumatoid anemia. Jt Bone Spine 78(2):131\u2013137","journal-title":"Jt Bone Spine"},{"issue":"10","key":"1736_CR28","doi-asserted-by":"publisher","first-page":"1856","DOI":"10.3390\/molecules24101856","volume":"24","author":"AM Metwaly","year":"2019","unstructured":"Metwaly AM, Lianlian Z, Luqi H, Deqiang D (2019) Black ginseng and its saponins: preparation, phytochemistry and pharmacological effects. Molecules 24(10):1856","journal-title":"Molecules"},{"issue":"8","key":"1736_CR29","doi-asserted-by":"publisher","first-page":"e02129","DOI":"10.1016\/j.heliyon.2019.e02129","volume":"5","author":"AC Mirza","year":"2019","unstructured":"Mirza AC, Panchal SS (2019) Safety evaluation of syringic acid: subacute oral toxicity studies in Wistar rats. Heliyon 5(8):e02129","journal-title":"Heliyon"},{"issue":"12","key":"1736_CR30","doi-asserted-by":"publisher","first-page":"4631","DOI":"10.1021\/jf800161u","volume":"56","author":"LA Pacheco-Palencia","year":"2008","unstructured":"Pacheco-Palencia LA, Mertens-Talcott S, Talcott ST (2008) Chemical composition, antioxidant properties, and thermal stability of a phytochemical enriched oil from Acai (Euterpe oleracea Mart.). J Agric Food Chem 56(12):4631\u20134636","journal-title":"J Agric Food Chem"},{"key":"1736_CR31","first-page":"7","volume":"6","author":"VP Patil","year":"2018","unstructured":"Patil VP, Patil PS, Wagh KS, Patil PH (2018) Evaluation of antiarthritic activity of pergularia daemia in freund\u2019s adjuvant induced arthritic rat model. World J Pharm Sci 6:7\u201324","journal-title":"World J Pharm Sci"},{"issue":"18","key":"1736_CR32","doi-asserted-by":"publisher","first-page":"4367","DOI":"10.3390\/ijms20184367","volume":"20","author":"KR Patil","year":"2019","unstructured":"Patil KR, Mahajan UB, Unger BS, Goyal SN, Belemkar S, Surana SJ, Patil CR (2019) Animal models of inflammation for screening of anti-inflammatory drugs: Implications for the discovery and development of phytopharmaceuticals. Int J Mol Sci 20(18):4367","journal-title":"Int J Mol Sci"},{"issue":"9","key":"1736_CR33","first-page":"1769","volume":"40","author":"N Percie du Sert","year":"2020","unstructured":"Percie du Sert N, Hurst V, Ahluwalia A, Alam S, Avey MT, Baker M, Dirnagl U (2020) The ARRIVE guidelines 2.0: updated guidelines for reporting animal research. JCBFM 40(9):1769\u20131777","journal-title":"JCBFM"},{"issue":"16","key":"1736_CR34","doi-asserted-by":"publisher","first-page":"6777","DOI":"10.1021\/jf800898p","volume":"56","author":"JM Pezzuto","year":"2008","unstructured":"Pezzuto JM (2008) Grapes and human health: a perspective. J Agric Food Chem 56(16):6777\u20136784","journal-title":"J Agric Food Chem"},{"key":"1736_CR35","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2020.11.005","author":"JE Pope","year":"2021","unstructured":"Pope JE, Choy EH (2021) C-reactive protein and implications in rheumatoid arthritis and associated comorbidities. Semin Arthritis Rheum. https:\/\/doi.org\/10.1016\/j.semarthrit.2020.11.005","journal-title":"Semin Arthritis Rheum"},{"key":"1736_CR36","doi-asserted-by":"publisher","first-page":"108790","DOI":"10.1016\/j.cbi.2019.108790","volume":"311","author":"AS Reis","year":"2019","unstructured":"Reis AS, Vogt AG, Pinz MP, Voss GT, da Fonseca CA, Paltian JJ, Soares MP (2019) Modulation of COX-2, INF-\u0263, glutamatergic and opioid systems contributes to antinociceptive, anti-inflammatory and anti-hyperalgesic effects of bis (3-amino-2-pyridine) diselenide. Chem Biol Interact 311:108790","journal-title":"Chem Biol Interact"},{"issue":"1","key":"1736_CR37","doi-asserted-by":"publisher","first-page":"102","DOI":"10.3390\/plants9010102","volume":"9","author":"MM Rob","year":"2020","unstructured":"Rob MM, Hossen K, Iwasaki A, Suenaga K, Kato-Noguchi H (2020) Phytotoxic activity and identification of phytotoxic substances from Schumannianthus dichotomus. Plants 9(1):102","journal-title":"Plants"},{"issue":"10","key":"1736_CR38","doi-asserted-by":"publisher","first-page":"442","DOI":"10.4103\/2221-1691.290869","volume":"10","author":"U Saleem","year":"2020","unstructured":"Saleem U, Zaib S, Khalid S, Anwar F, Akhtar MF, Ahmad B (2020) Chemical characterization, docking studies, anti-arthritic activity and acute oral toxicity of Convolvulus arvensis L. leaves. Asian Pac J Trop Biomed 10(10):442","journal-title":"Asian Pac J Trop Biomed"},{"key":"1736_CR39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13075-020-2097-2","volume":"22","author":"S Samarpita","year":"2020","unstructured":"Samarpita S, Kim JY, Rasool MK, Kim KS (2020) Investigation of toll-like receptor (TLR) 4 inhibitor TAK-242 as a new potential anti-rheumatoid arthritis drug. Arthritis Res Ther 22:1\u201310","journal-title":"Arthritis Res Ther"},{"issue":"5","key":"1736_CR40","first-page":"1","volume":"1","author":"S Shimsa","year":"2024","unstructured":"Shimsa S, Mondal S, Mini S (2024) Syringic acid: a promising phenolic phytochemical with extensive therapeutic applications. RDFFP 1(5):1\u201314","journal-title":"RDFFP"},{"issue":"1","key":"1736_CR41","first-page":"41","volume":"14","author":"C Sun","year":"2018","unstructured":"Sun C, Yuan Y, Omari-Siaw E, Tong S, Zhu Y, Wang Q, Xu X (2018) An efficient HPLC method for determination of syringic acid liposome in rats plasma and mice tissues: pharmacokinetic and biodistribution application. Curr Pharm Anal 14(1):41\u201352","journal-title":"Curr Pharm Anal"},{"issue":"2","key":"1736_CR42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3892\/etm.2021.10280","volume":"22","author":"S Sun","year":"2021","unstructured":"Sun S, Du Y, Li S, Gao B, Xia R, Cao W, Zhu E (2021) Anti-inflammatory activity of different isolated sites of Chloranthus serratus in complete Freund\u2019s adjuvant-induced arthritic rats. Exp Ther Med 22(2):1\u201314","journal-title":"Exp Ther Med"},{"key":"1736_CR43","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1483791","author":"A Tandon","year":"2018","unstructured":"Tandon A, Singh SJ, Chaturvedi RK (2018) Stem cells as potential targets of polyphenols in multiple sclerosis and Alzheimer\u2019s disease. Biomed Res Int. https:\/\/doi.org\/10.1155\/2018\/1483791","journal-title":"Biomed Res Int"},{"issue":"1","key":"1736_CR44","doi-asserted-by":"publisher","first-page":"85","DOI":"10.20884\/2.procicma.2023.2.1.7808","volume":"2","author":"SW Tiyah","year":"2023","unstructured":"Tiyah SW, Ratnaningtyas N, Wibowo E, Mumpuni A, Ekowati N (2023) Ganoderma lucidum as anti-inflammatory agent on the level of albumin and globulin in rat (Rattus Norvegicus) rheumatoid arthritis (RA) Model. Proceeding ICMA-SURE 2(1):85\u201393","journal-title":"Proceeding ICMA-SURE"},{"issue":"8","key":"1736_CR45","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1080\/15376516.2017.1349227","volume":"27","author":"P Velu","year":"2017","unstructured":"Velu P, Vinothkumar V, Babukumar S, Ramachandhiran D (2017) Chemopreventive effect of syringic acid on 7, 12-dimethylbenz (a) anthracene induced hamster buccal pouch carcinogenesis. Toxicol Mech Methods 27(8):631\u2013640","journal-title":"Toxicol Mech Methods"},{"issue":"11","key":"1736_CR46","doi-asserted-by":"publisher","first-page":"e21635","DOI":"10.1016\/j.heliyon.2023.e21635","volume":"9","author":"L-S Yan","year":"2023","unstructured":"Yan L-S, Cheng BC-Y, Wang Y-W, Zhang S-F, Qiu X-Y, Kang J-Y, Zhang Y (2023) Xuelian injection ameliorates complete Freund\u2019s adjuvant-induced acute arthritis in rats via inhibiting TLR4 signaling. Heliyon 9(11):e21635","journal-title":"Heliyon"},{"key":"1736_CR47","doi-asserted-by":"publisher","first-page":"107882","DOI":"10.1016\/j.intimp.2021.107882","volume":"98","author":"Y Yang","year":"2021","unstructured":"Yang Y, Sheng Q, Nie Z, Liu L, Zhang W, Chen G, Xie J (2021) Daphnetin inhibits spinal glial activation via Nrf2\/HO-1\/NF-\u03baB signaling pathway and attenuates CFA-induced inflammatory pain. Int Immunopharmacol 98:107882","journal-title":"Int Immunopharmacol"},{"issue":"6","key":"1736_CR48","doi-asserted-by":"publisher","first-page":"174","DOI":"10.14715\/cmb\/2022.68.6.28","volume":"68","author":"Y Zamudio-Cuevas","year":"2022","unstructured":"Zamudio-Cuevas Y, Mart\u00ednez-Flores K, Mart\u00ednez-Nava GA, Clavijo-Cornejo D, Fern\u00e1ndez-Torres J, S\u00e1nchez-S\u00e1nchez R (2022) Rheumatoid Arthritis and Oxidative Stress. Cell Mol Biol 68(6):174\u2013184","journal-title":"Cell Mol Biol"},{"key":"1736_CR49","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1016\/j.jep.2018.04.051","volume":"225","author":"Q Zhang","year":"2018","unstructured":"Zhang Q, Yu Y, Li J, Guan Y, Huang J, Wang Z, Li J (2018) Anti-arthritic activities of ethanol extracts of Circaea mollis Sieb. & Zucc. (whole plant) in rodents. J Ethnopharmacol 225:359\u2013366","journal-title":"J Ethnopharmacol"},{"issue":"1","key":"1736_CR50","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1080\/10717544.2020.1818883","volume":"27","author":"F Zhang","year":"2020","unstructured":"Zhang F, Liu Z, He X, Li Z, Shi B, Cai F (2020) \u03b2-Sitosterol-loaded solid lipid nanoparticles ameliorate complete Freund\u2019s adjuvant-induced arthritis in rats: involvement of NF-\u043aB and HO-1\/Nrf-2 pathway. Drug Deliv 27(1):1329\u20131341","journal-title":"Drug Deliv"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-025-01736-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-025-01736-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-025-01736-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T07:02:17Z","timestamp":1750230137000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-025-01736-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["1736"],"URL":"https:\/\/doi.org\/10.1007\/s10787-025-01736-8","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"25 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 March 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All authors declare that there are no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}