{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T16:53:08Z","timestamp":1793379188882,"version":"4.5.0"},"reference-count":101,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T00:00:00Z","timestamp":1755129600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s10787-025-01912-w","type":"journal-article","created":{"date-parts":[[2025,8,14]],"date-time":"2025-08-14T14:54:39Z","timestamp":1755183279000},"page":"5085-5096","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Therapeutic potential of Boswellia serrata in arthritis management: mechanistic insights into COX-2, 5-LOX, and NF\u0138B modulation"],"prefix":"10.1007","volume":"33","author":[{"given":"Koleshwar","family":"Mahto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1796-4913","authenticated-orcid":false,"given":"Omkar Kumar","family":"Kuwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aayushi","family":"Maloo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,8,14]]},"reference":[{"issue":"1","key":"1912_CR1","doi-asserted-by":"publisher","first-page":"168","DOI":"10.1186\/s12917-025-04587-1","volume":"21","author":"SA Abdelnour","year":"2025","unstructured":"Abdelnour SA, Abdelaal M, Sindi RA, Alfattah MA, Khalil WA, Bahgat LB, Sheiha AM (2025) Physio-metabolic response, immune function, epigenetic markers, and reproductive performance of rabbits under environmental stress: the mitigating role of boswellia essential oil nanoemulsion. BMC Vet Res 21(1):168","journal-title":"BMC Vet Res"},{"key":"1912_CR2","first-page":"199","volume":"12","author":"S Ali","year":"2023","unstructured":"Ali S, Ali SA, Kondrapu P, Tripathi N, Kumar PB, Prasad PD, Tonape MM, Terse PP, Ameen MP, Kumar S (2023) A brief review of pathophysiology and management of different types of arthritis. Eur Chem Bull. 12:199","journal-title":"Eur Chem Bull."},{"key":"1912_CR3","doi-asserted-by":"publisher","unstructured":"Al-kaf A G, Al-Yahawi A A (2025). The pharmacotherapy of corticosteroids. intechOpen Book Series. https:\/\/doi.org\/10.5772\/intechopen.1008693","DOI":"10.5772\/intechopen.1008693"},{"issue":"1","key":"1912_CR4","doi-asserted-by":"publisher","first-page":"7381625","DOI":"10.1155\/2020\/7381625","volume":"2020","author":"VK Alluri","year":"2020","unstructured":"Alluri VK, Kundimi S, Sengupta K, Golakoti T, Kilari EK (2020) An anti-inflammatory composition of Boswellia serrata resin extracts alleviates pain and protects cartilage in monoiodoacetate-induced osteoarthritis in rats. Evid-Based Complement Altern Med 2020(1):7381625","journal-title":"Evid-Based Complement Altern Med"},{"issue":"1","key":"1912_CR5","doi-asserted-by":"publisher","first-page":"8","DOI":"10.4103\/jfmpc.jfmpc_739_24","volume":"14","author":"AD Alshammari","year":"2025","unstructured":"Alshammari AD, Aldhafeeri MM, Aldhafeeri AM, Alanzi MA, Almutairi MB, Alrasheedi JA, Alsurur TA, Alshammri AD (2025) The type of infections and the use of antibiotics among patients with rheumatoid arthritis: a review. J Family Med Prim Care 14(1):8\u201314","journal-title":"J Family Med Prim Care"},{"key":"1912_CR6","doi-asserted-by":"publisher","first-page":"1483548","DOI":"10.3389\/fphar.2025.1483548","volume":"16","author":"I Anjum","year":"2025","unstructured":"Anjum I, Nasir A, Naseer F, Ibrahim A, Rehman B, Bashir F, Tul Ain Q (2025) Exploring the anti-inflammatory effects of phytochemicals in attenuating interstitial cystitis-a literature review. Front Pharmacol 16:1483548","journal-title":"Front Pharmacol"},{"key":"1912_CR7","doi-asserted-by":"publisher","first-page":"117899","DOI":"10.1016\/j.bmc.2024.117899","volume":"112","author":"M Arfeen","year":"2024","unstructured":"Arfeen M, Srivastava A, Srivastava N, Khan RA, Al-mahmoud S, Mohammed HA (2024) Design, classification, and adverse effects of NSAIDs: a review on recent advancements. Bioorganic Med Chem 112:117899","journal-title":"Bioorganic Med Chem"},{"key":"1912_CR8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2022.115200","volume":"292","author":"D Banji","year":"2022","unstructured":"Banji D, Banji OJ, Rashida S, Alshahrani S, Alqahtani SS (2022) Bioavailability, anti-inflammatory and anti-arthritic effect of acetyl keto boswellic acid and its combination with methotrexate in an arthritic animal model. J Ethnopharmacol 292:115200","journal-title":"J Ethnopharmacol"},{"issue":"1","key":"1912_CR9","first-page":"177","volume":"17","author":"A Bashar","year":"2025","unstructured":"Bashar A, Kadhem W (2025) Study of the effect of Boswellia serrata in reducing the effects associated with induced arthritis in male albino rats. Agric Biotechnol J 17(1):177\u2013192","journal-title":"Agric Biotechnol J"},{"issue":"1","key":"1912_CR10","doi-asserted-by":"publisher","first-page":"29","DOI":"10.36118\/pharmadvances.2023.53","volume":"5","author":"M Biagi","year":"2023","unstructured":"Biagi M, Rigillo G, Sarill M, Collotta D, Di Giacomo S, Di Sotto A, Grilli M, Luceri C, Milella L, Sangiovanni E (2023) From preclinical to clinical evidence: exploring the multiple perspectives and healing power of Boswellia serrata Roxb ex Colebr. Pharmadvances 5(1):29\u201353","journal-title":"Pharmadvances"},{"issue":"4","key":"1912_CR11","doi-asserted-by":"publisher","first-page":"129","DOI":"10.26444\/jpccr\/99597","volume":"12","author":"J Bryda","year":"2018","unstructured":"Bryda J, Watroba S (2018) The proinflammatory role of lipoxygenases in rheumatoid arthritis. J Pre-Clin Clin Res 12(4): 129\u2013134","journal-title":"J Pre-Clin Clin Res"},{"issue":"1","key":"1912_CR12","doi-asserted-by":"publisher","first-page":"4","DOI":"10.2174\/0115733971279100240328063232","volume":"21","author":"S Chaudhary","year":"2025","unstructured":"Chaudhary S, Sharma S, Fuloria S (2025) A panoramic review on the management of rheumatoid arthritis through herbalism. Curr Rheumatol Rev 21(1):4\u201324","journal-title":"Curr Rheumatol Rev"},{"issue":"7","key":"1912_CR13","doi-asserted-by":"publisher","first-page":"734","DOI":"10.3390\/cells8070734","volume":"8","author":"M-C Choi","year":"2019","unstructured":"Choi M-C, Jo J, Park J, Kang HK, Park Y (2019) NF-\u03baB signaling pathways in osteoarthritic cartilage destruction. Cells 8(7):734","journal-title":"Cells"},{"issue":"6","key":"1912_CR14","doi-asserted-by":"publisher","first-page":"3218","DOI":"10.3390\/ijms25063218","volume":"25","author":"Y-J Choi","year":"2024","unstructured":"Choi Y-J, Jung JI, Bae J, Lee JK, Kim EJ (2024) Evaluating the anti-osteoarthritis potential of standardized boswellia serrata gum resin extract in alleviating knee joint pathology and inflammation in osteoarthritis-induced models. Int J Mol Sci 25(6):3218","journal-title":"Int J Mol Sci"},{"issue":"7","key":"1912_CR15","doi-asserted-by":"publisher","first-page":"673","DOI":"10.1016\/j.autrev.2016.03.003","volume":"15","author":"P Conigliaro","year":"2016","unstructured":"Conigliaro P, Chimenti M, Triggianese P, Sunzini F, Novelli L, Perricone C, Perricone R (2016) Autoantibodies in inflammatory arthritis. Autoimmun Rev 15(7):673\u2013683","journal-title":"Autoimmun Rev"},{"issue":"10","key":"1912_CR16","doi-asserted-by":"publisher","first-page":"60","DOI":"10.53388\/TMR20240128002","volume":"9","author":"N Cui","year":"2024","unstructured":"Cui N, Li M, Wang Y, Meng Q, Shi Y, Ding Y (2024) Boswellic acids: a review on its pharmacological properties, molecular mechanism and bioavailability. Tradit Med Res 9(10):60","journal-title":"Tradit Med Res"},{"issue":"11","key":"1912_CR17","doi-asserted-by":"publisher","first-page":"2129","DOI":"10.3390\/antiox11112129","volume":"11","author":"R D\u2019Amico","year":"2022","unstructured":"D\u2019Amico R, Fusco R, Cordaro M, Interdonato L, Crupi R, Gugliandolo E, Di Paola D, Peritore AF, Siracusa R, Impellizzeri D (2022) Modulation of NRF-2 pathway contributes to the therapeutic effects of Boswellia serrata gum resin extract in a model of experimental autoimmune myocarditis. Antioxidants 11(11):2129","journal-title":"Antioxidants"},{"issue":"1","key":"1912_CR18","doi-asserted-by":"publisher","DOI":"10.4291\/wjgp.v16.i1.101481","volume":"16","author":"H Eldew","year":"2025","unstructured":"Eldew H, Soldera J (2025) Evaluation of biological therapies in autoimmune hepatitis: a case-based systematic review. World J Gastrointest Pathophysiol 16(1):101481","journal-title":"World J Gastrointest Pathophysiol"},{"issue":"2","key":"1912_CR19","first-page":"1313","volume":"19","author":"HM Eltahir","year":"2020","unstructured":"Eltahir HM, Fawzy MA, Mohamed EM, Alrehany MA, Shehata AM, Abouzied MM (2020) Antioxidant, anti-inflammatory and anti-fibrotic effects of Boswellia serrata gum resin in CCl4-induced hepatotoxicity. Exp Ther Med 19(2):1313\u20131321","journal-title":"Exp Ther Med"},{"key":"1912_CR20","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1007\/s00264-021-04938-1","volume":"45","author":"T Fang","year":"2021","unstructured":"Fang T, Zhou X, Jin M, Nie J, Li X (2021) Molecular mechanisms of mechanical load-induced osteoarthritis. Int Orthop 45:1125\u20131136","journal-title":"Int Orthop"},{"key":"1912_CR21","doi-asserted-by":"publisher","unstructured":"Feuerstein JD, Rubin DT, Aberra FN, Yarur A, Malter L (2025) Appropriate use and complications of corticosteroids in inflammatory bowel disease: a comprehensive review. Clin Gastroenterol Hepatol 1542\u20133565. https:\/\/doi.org\/10.1016\/j.cgh.2025.05.019","DOI":"10.1016\/j.cgh.2025.05.019"},{"issue":"1","key":"1912_CR22","doi-asserted-by":"publisher","first-page":"33","DOI":"10.17159\/sadj.v80i01.20071","volume":"80","author":"J Fourie","year":"2025","unstructured":"Fourie J, Laubscher D, Simelane T (2025) Methotrexate-induced oral mucositis in patients with rheumatoid arthritis: a case series and literature review. S Afr Dent J 80(1):33\u201341","journal-title":"S Afr Dent J"},{"issue":"2","key":"1912_CR23","doi-asserted-by":"publisher","first-page":"371","DOI":"10.3390\/antiox12020371","volume":"12","author":"E Franco-Trepat","year":"2023","unstructured":"Franco-Trepat E, Alonso-P\u00e9rez A, Guill\u00e1n-Fresco M, L\u00f3pez-Fag\u00fandez M, Pazos-P\u00e9rez A, Crespo-Golmar A, Bel\u00e9n Bravo S, L\u00f3pez-L\u00f3pez V, Jorge-Mora A, Cer\u00f3n-Carrasco JP (2023) \u0392 boswellic acid blocks articular innate immune responses: an in silico and in vitro approach to traditional medicine. Antioxidants 12(2):371","journal-title":"Antioxidants"},{"issue":"5","key":"1912_CR24","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1039\/D0QO01210F","volume":"8","author":"F Ghirga","year":"2021","unstructured":"Ghirga F, Quaglio D, Mori M, Cammarone S, Iazzetti A, Goggiamani A, Ingallina C, Botta B, Calcaterra A (2021) A unique high-diversity natural product collection as a reservoir of new therapeutic leads. Org Chem Front 8(5):996\u20131025","journal-title":"Org Chem Front"},{"issue":"11","key":"1912_CR25","doi-asserted-by":"publisher","first-page":"2167","DOI":"10.1007\/s00210-021-02154-7","volume":"394","author":"AA Gomaa","year":"2021","unstructured":"Gomaa AA, Farghaly HA, Abdel-Wadood YA, Gomaa GA (2021) Potential therapeutic effects of boswellic acids\/Boswellia serrata extract in the prevention and therapy of type 2 diabetes and Alzheimer\u2019s disease. Naunyn Schmiedebergs Arch Pharmacol 394(11):2167\u20132185","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"1912_CR26","doi-asserted-by":"publisher","first-page":"S18","DOI":"10.1016\/S0720-048X(98)00038-2","volume":"27","author":"W Grassi","year":"1998","unstructured":"Grassi W, De Angelis R, Lamanna G, Cervini C (1998) The clinical features of rheumatoid arthritis. Eur J Radiol 27:S18\u2013S24","journal-title":"Eur J Radiol"},{"issue":"4","key":"1912_CR27","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1007\/s43450-022-00266-6","volume":"32","author":"A Guleria","year":"2022","unstructured":"Guleria A, Kamboj A, Kaushal J, Anupam K, Bhatnagar A (2022) A molecular insight into significance of functional foods in better management of rheumatoid arthritis. Rev Bras Farmacogn 32(4):502\u2013513","journal-title":"Rev Bras Farmacogn"},{"issue":"8","key":"1912_CR28","doi-asserted-by":"publisher","first-page":"1900034","DOI":"10.1002\/adtp.201900034","volume":"2","author":"AJ Hayes","year":"2019","unstructured":"Hayes AJ, Melrose J (2019) Glycosaminoglycan and proteoglycan biotherapeutics in articular cartilage protection and repair strategies: novel approaches to visco-supplementation in orthobiologics. Adv Ther 2(8):1900034","journal-title":"Adv Ther"},{"issue":"4","key":"1912_CR29","doi-asserted-by":"publisher","first-page":"261","DOI":"10.2174\/157339707782408955","volume":"3","author":"Y Henrotin","year":"2007","unstructured":"Henrotin Y, Blanco FJ, Aigner T, Kurz B (2007) The significance of oxidative stress in articular cartilage ageing and degradation. Curr Rheumatol Rev 3(4):261\u2013274","journal-title":"Curr Rheumatol Rev"},{"issue":"22","key":"1912_CR30","doi-asserted-by":"publisher","first-page":"16468","DOI":"10.3390\/ijms242216468","volume":"24","author":"E Horv\u00e1th","year":"2023","unstructured":"Horv\u00e1th E, S\u00f3lyom \u00c1, Sz\u00e9kely J, Nagy EE, Popoviciu H (2023) Inflammatory and metabolic signaling interfaces of the hypertrophic and senescent chondrocyte phenotypes associated with osteoarthritis. Int J Mol Sci 24(22):16468","journal-title":"Int J Mol Sci"},{"key":"1912_CR31","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1016\/j.fitote.2012.10.002","volume":"84","author":"J H\u00fcsch","year":"2013","unstructured":"H\u00fcsch J, Bohnet J, Fricker G, Skarke C, Artaria C, Appendino G, Schubert-Zsilavecz M, Abdel-Tawab M (2013) Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome\u00ae) of Boswellia extract. Fitoterapia 84:89\u201398","journal-title":"Fitoterapia"},{"issue":"8","key":"1912_CR32","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1080\/13543776.2024.2369626","volume":"34","author":"H Hussain","year":"2024","unstructured":"Hussain H, Wang D, El-Seedi HR, Rashan L, Ahmed I, Abbas M, Mamadalieva NZ, Sultani HN, Hussain MI, Shah STA (2024) Therapeutic potential of boswellic acids: an update patent review (2016\u20132023). Expert Opin Ther Pat 34(8):723\u2013732","journal-title":"Expert Opin Ther Pat"},{"issue":"4","key":"1912_CR33","doi-asserted-by":"publisher","first-page":"249","DOI":"10.2174\/187152811304140915152102","volume":"13","author":"P Joshi","year":"2014","unstructured":"Joshi P, Dhaneshwar SS (2014) An update on disease modifying antirheumatic drugs. Inflamm Allergy-Drug Targets 13(4):249\u2013261","journal-title":"Inflamm Allergy-Drug Targets"},{"issue":"3","key":"1912_CR34","doi-asserted-by":"publisher","first-page":"632","DOI":"10.55730\/1300-0144.6010","volume":"55","author":"M Kara","year":"2025","unstructured":"Kara M, Alp G, Pekdiker M, Ketenci S, Porreca A, Cinakli H (2025) Evaluating leflunomide and methotrexate combination vs. monotherapy in rheumatoid and psoriatic arthritis. Turk J Med Sci 55(3):632\u2013643","journal-title":"Turk J Med Sci"},{"issue":"7","key":"1912_CR35","doi-asserted-by":"publisher","first-page":"775","DOI":"10.3390\/antiox13070775","volume":"13","author":"M Kciuk","year":"2024","unstructured":"Kciuk M, Garg A, Rohilla M, Chaudhary R, Dhankhar S, Dhiman S, Bansal S, Saini M, Singh TG, Chauhan S (2024) Therapeutic potential of plant-derived compounds and plant extracts in rheumatoid arthritis\u2014comprehensive review. Antioxidants 13(7):775","journal-title":"Antioxidants"},{"key":"1912_CR36","doi-asserted-by":"publisher","first-page":"1587215","DOI":"10.3389\/fphar.2025.1587215","volume":"16","author":"S Khanam","year":"2025","unstructured":"Khanam S, Mishra P, Faruqui T, Alam P, Albalawi T, Siddiqui F, Rafi Z, Khan S (2025) Plant-based secondary metabolites as natural remedies: a comprehensive review on terpenes and their therapeutic applications. Front Pharmacol 16:1587215","journal-title":"Front Pharmacol"},{"key":"1912_CR37","unstructured":"Kibuuka R S (2025) Cellular mechanisms modulated by steroids in inflammatory disease management: exploring NF-\u03baB inhibition and cytokine production pathways"},{"key":"1912_CR39","doi-asserted-by":"crossref","unstructured":"Kondreddy V, Gadiraju B, Magisetty J (2025) Evidence-based complementary therapies for the management of. Unveiling Ulcerative Colitis-A Compr Approach Underst Manag Compr Approach Underst Manag: 125-144.","DOI":"10.5772\/intechopen.1007705"},{"issue":"39","key":"1912_CR40","doi-asserted-by":"publisher","first-page":"3212","DOI":"10.2174\/1381612829666221021152354","volume":"28","author":"M Kumar","year":"2022","unstructured":"Kumar M, Kumar D, Kumar S, Kumar A, Mandal UK (2022) A recent review on bio-availability enhancement of poorly water-soluble drugs by using bioenhancer and nanoparticulate drug delivery system. Curr Pharm des 28(39):3212\u20133224","journal-title":"Curr Pharm des"},{"issue":"5","key":"1912_CR41","first-page":"375","volume":"44","author":"B Kumar","year":"2025","unstructured":"Kumar B, Ghaytidak AB, Pandey AK, Somepalli RR, Sarda P, Raychaudhuri SP, Rokkam MP (2025) A standardized Boswellia serrata extract improves knee joint function and cartilage morphology in human volunteers with mild to moderate osteoarthritis in a randomized placebo-controlled study. J Am Nutr Assoc 44(5):375\u2013386","journal-title":"J Am Nutr Assoc"},{"key":"1912_CR42","doi-asserted-by":"crossref","unstructured":"Kumar R, Tiwari S (2024) Declining Boswellia serrata population in Eastern India: the interplay of climate change and socioeconomic influences","DOI":"10.21203\/rs.3.rs-5277796\/v1"},{"issue":"1","key":"1912_CR43","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10048-025-00801-2","volume":"26","author":"OK Kunwar","year":"2025","unstructured":"Kunwar OK, Singh S (2025) Neuroinflammation and neurodegeneration in Huntington\u2019s disease: Genetic hallmarks, role of metals and organophosphates. Neurogenetics 26(1):1\u201315","journal-title":"Neurogenetics"},{"key":"1912_CR44","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01698-x","author":"OK Kuwar","year":"2025","unstructured":"Kuwar OK, Kalia N (2025) Anti-inflammatory and antioxidant effects of baicalein: targeting Nrf2, and NF\u0138B in neurodegenerative disease. Inflammopharmacology. https:\/\/doi.org\/10.1007\/s10787-025-01698-x","journal-title":"Inflammopharmacology"},{"key":"1912_CR45","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01839-2","author":"OK Kuwar","year":"2025","unstructured":"Kuwar OK, Singh S (2025) Baicalein-mediated regulation of Nrf2\/ARE, NF\u0138B, and MAPK signaling in Huntington\u2019s disease: a promising strategy against neuroinflammation and neurodegeneration. Inflammopharmacology. https:\/\/doi.org\/10.1007\/s10787-025-01839-2","journal-title":"Inflammopharmacology"},{"issue":"4","key":"1912_CR46","doi-asserted-by":"publisher","first-page":"576","DOI":"10.1016\/j.bbadis.2016.01.003","volume":"1862","author":"P Lepetsos","year":"2016","unstructured":"Lepetsos P, Papavassiliou AG (2016) ROS\/oxidative stress signaling in osteoarthritis. Biochimica Et Biophysica Acta (BBA)-Mol Basis Dis 1862(4):576\u2013591","journal-title":"Biochimica Et Biophysica Acta (BBA)-Mol Basis Dis"},{"issue":"3","key":"1912_CR47","doi-asserted-by":"publisher","first-page":"99","DOI":"10.3892\/mmr.2022.12615","volume":"25","author":"S Liu","year":"2022","unstructured":"Liu S, Deng Z, Chen K, Jian S, Zhou F, Yang Y, Fu Z, Xie H, Xiong J, Zhu W (2022) Cartilage tissue engineering: from proinflammatory and anti-inflammatory cytokines to osteoarthritis treatments. Mol Med Rep 25(3):99","journal-title":"Mol Med Rep"},{"key":"1912_CR48","doi-asserted-by":"publisher","first-page":"1586361","DOI":"10.3389\/fimmu.2025.1586361","volume":"16","author":"S Liu","year":"2025","unstructured":"Liu S, Yuan Z, Rao S, Li W, Wu T, Deng S, Zhong Y, Lin J, Guo W, Yuan S (2025) Adverse drug reactions related to methotrexate: a real-world pharmacovigilance study using the FAERS database from 2004 to 2024. Front Immunol 16:1586361","journal-title":"Front Immunol"},{"key":"1912_CR49","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S194921","author":"SN Ma","year":"2019","unstructured":"Ma SN, Zaman Huri H, Yahya F (2019) Drug-related problems in patients with rheumatoid arthritis. Ther Clin Risk Manag. https:\/\/doi.org\/10.2147\/TCRM.S194921","journal-title":"Ther Clin Risk Manag"},{"issue":"6","key":"1912_CR50","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1002\/ppp3.10563","volume":"6","author":"P Mad\u011bra","year":"2024","unstructured":"Mad\u011bra P, Vahal\u00edk P, Hamdiah S, Hu\u0161kov\u00e1 K, Sekava J, Attorre F, La Montagna D, De Sanctis M, Netek R, Bongers F (2024) Distribution, ecology, and threats assessment of 11 endemic frankincense tree taxa (Boswellia) in the Socotra Archipelago (Yemen). Plants People Planet 6(6):1552\u20131571","journal-title":"Plants People Planet"},{"issue":"2","key":"1912_CR51","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1007\/s40122-021-00260-1","volume":"10","author":"A Magni","year":"2021","unstructured":"Magni A, Agostoni P, Bonezzi C, Massazza G, Men\u00e8 P, Savarino V, Fornasari D (2021) Management of osteoarthritis: expert opinion on NSAIDs. Pain Ther 10(2):783\u2013808","journal-title":"Pain Ther"},{"key":"1912_CR52","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01846-3","author":"K Mahto","year":"2025","unstructured":"Mahto K, Kuwar OK, Maloo A, Kalia N (2025) Therapeutic potential of luteolin in neurodegenerative disorders: targeting Nrf2, NF\u0138B, MAPK, and JAK-STAT pathways to combat neuroinflammation and apoptosis. Inflammopharmacology. https:\/\/doi.org\/10.1007\/s10787-025-01846-3","journal-title":"Inflammopharmacology"},{"key":"1912_CR53","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.735247","volume":"12","author":"M Majeed","year":"2021","unstructured":"Majeed M, Nagabhushanam K, Lawrence L, Nallathambi R, Thiyagarajan V, Mundkur L (2021) Boswellia serrata extract containing 30% 3-acetyl-11-keto-boswellic acid attenuates inflammatory mediators and preserves extracellular matrix in collagen-induced arthritis. Front Physiol 12:735247","journal-title":"Front Physiol"},{"issue":"1","key":"1912_CR54","doi-asserted-by":"publisher","DOI":"10.1016\/j.explore.2024.103099","volume":"21","author":"A Majumdar","year":"2025","unstructured":"Majumdar A, Prasad MAVV, Gandavarapu SR, Reddy KSK, Sureja V, Kheni D, Dubey V (2025) Efficacy and safety evaluation of Boswellia serrata and Curcuma longa extract combination in the management of chronic lower back pain: a randomised, double-blind, placebo-controlled clinical study. Explore 21(1):103099","journal-title":"Explore"},{"issue":"12","key":"1912_CR55","doi-asserted-by":"publisher","first-page":"2962","DOI":"10.1111\/bcp.15972","volume":"90","author":"A Manhapra","year":"2024","unstructured":"Manhapra A, MacLean RR, Rosenheck R, Becker WC (2024) Are opioids effective analgesics and is physiological opioid dependence benign? Revising current assumptions to effectively manage long-term opioid therapy and its deprescribing. Br J Clin Pharmacol 90(12):2962\u20132976","journal-title":"Br J Clin Pharmacol"},{"key":"1912_CR56","unstructured":"El Mansouri FE (2016) Role of histone methylation in the regulation of COX-2, iNOS, and mPGES-1 gene expression in human chondrocytes: implication for osteoarthritis"},{"issue":"21","key":"1912_CR57","doi-asserted-by":"publisher","first-page":"11656","DOI":"10.3390\/ijms252111656","volume":"25","author":"A Maouche","year":"2024","unstructured":"Maouche A, Boumediene K, Baug\u00e9 C (2024) Bioactive compounds in osteoarthritis: molecular mechanisms and therapeutic roles. Int J Mol Sci 25(21):11656","journal-title":"Int J Mol Sci"},{"key":"1912_CR58","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2019.116786","volume":"234","author":"E-SE Mehana","year":"2019","unstructured":"Mehana E-SE, Khafaga AF, El-Blehi SS (2019) The role of matrix metalloproteinases in osteoarthritis pathogenesis: an updated review. Life Sci 234:116786","journal-title":"Life Sci"},{"issue":"2","key":"1912_CR59","doi-asserted-by":"publisher","first-page":"349","DOI":"10.3390\/nu17020349","volume":"17","author":"LK Mende","year":"2025","unstructured":"Mende LK, Kuthati Y, Wong C-S (2025) Curcumin and vitamin D supplement attenuates knee osteoarthritis progression in ACLT+ MMx rat model: effect on cartilage protection and pain reduction. Nutrients 17(2):349","journal-title":"Nutrients"},{"key":"1912_CR60","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110668","volume":"122","author":"A Meyiah","year":"2023","unstructured":"Meyiah A, Shawkat MY, Rehman NU, Al-Harrasi A, Elkord E (2023) Effect of boswellic acids on T cell proliferation and activation. Int Immunopharmacol 122:110668","journal-title":"Int Immunopharmacol"},{"issue":"12","key":"1912_CR61","doi-asserted-by":"publisher","first-page":"1650","DOI":"10.3390\/ph17121650","volume":"17","author":"A Meyiah","year":"2024","unstructured":"Meyiah A, Avula SK, Al-Harrasi A, Elkord E (2024) Effects of 1H\u20131, 2, 3-triazole derivatives of 3-O-acetyl-11-keto-beta-boswellic acid from Boswellia sacra resin on T-cell proliferation and activation. Pharmaceuticals 17(12):1650","journal-title":"Pharmaceuticals"},{"issue":"1","key":"1912_CR62","doi-asserted-by":"publisher","first-page":"3075293","DOI":"10.1155\/2018\/3075293","volume":"2018","author":"M Minguzzi","year":"2018","unstructured":"Minguzzi M, Cetrullo S, D\u2019Adamo S, Silvestri Y, Flamigni F, Borz\u00ec RM (2018) Emerging players at the intersection of chondrocyte loss of maturational arrest, oxidative stress, senescence and low-grade inflammation in osteoarthritis. Oxid Med Cell Longev 2018(1):3075293","journal-title":"Oxid Med Cell Longev"},{"issue":"1","key":"1912_CR63","doi-asserted-by":"publisher","first-page":"95","DOI":"10.3390\/ijms24010095","volume":"24","author":"KD Moudgil","year":"2022","unstructured":"Moudgil KD, Venkatesha SH (2022) The anti-inflammatory and immunomodulatory activities of natural products to control autoimmune inflammation. Int J Mol Sci 24(1):95","journal-title":"Int J Mol Sci"},{"issue":"4","key":"1912_CR64","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.3892\/etm.2016.3045","volume":"11","author":"C Negrei","year":"2016","unstructured":"Negrei C, Bojinca V, Balanescu A, Bojinca M, Baconi D, Spandidos DA, Tsatsakis AM, Stan M (2016) Management of rheumatoid arthritis: impact and risks of various therapeutic approaches. Exp Ther Med 11(4):1177\u20131183","journal-title":"Exp Ther Med"},{"issue":"6","key":"1912_CR65","doi-asserted-by":"publisher","first-page":"602","DOI":"10.1093\/rheumatology\/kep028","volume":"48","author":"K Nistala","year":"2009","unstructured":"Nistala K, Wedderburn LR (2009) Th17 and regulatory T cells: rebalancing pro-and anti-inflammatory forces in autoimmune arthritis. Rheumatology 48(6):602\u2013606","journal-title":"Rheumatology"},{"key":"1912_CR66","first-page":"2962","volume":"26","author":"AT Pawar","year":"2020","unstructured":"Pawar AT, Baheti AM, Adate-More P, Upaganlawar A (2020) Conventional therapy for rheumatoid arthritis. Nat Products Manag Arthr Disorders 26:2962\u20132970","journal-title":"Nat Products Manag Arthr Disorders"},{"issue":"10","key":"1912_CR67","doi-asserted-by":"publisher","first-page":"867","DOI":"10.1080\/13543784.2023.2269838","volume":"32","author":"S Priya","year":"2023","unstructured":"Priya S, Singhvi G (2023) Insights into the anti-inflammatory and anti-arthritic potential of 3-acetyl-11-keto-\u03b2-boswellic acid as a therapeutic approach in Rheumatoid Arthritis. Expert Opin Investig Drugs 32(10):867\u2013871","journal-title":"Expert Opin Investig Drugs"},{"issue":"15","key":"1912_CR68","first-page":"4080","volume":"28","author":"F Puntillo","year":"2024","unstructured":"Puntillo F, Giglio M, Corriero A, Coaccioli S, Fornasari D, Iolascon G, Luxardo N, Sardo S, Paladini A, Schweiger V (2024) Unraveling the joints: a narrative review of osteoarthritis. Eur Rev Med Pharmacol Sci 28(15):4080\u20134104","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"1912_CR69","doi-asserted-by":"crossref","unstructured":"Puttachar SL, Sayed AM, Godkar TM, Mascarenhas V, Fernandes DD, Correia SR, Thomas S, Pillai SB, Naik SM (2025) Extraction and standardization of biojoin trademark product for joint health and muscle strength","DOI":"10.22214\/ijraset.2025.66358"},{"issue":"3","key":"1912_CR70","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1007\/s00210-023-02725-w","volume":"397","author":"EA Ragab","year":"2024","unstructured":"Ragab EA, Abd El-Wahab MF, Doghish AS, Salama RM, Eissa N, Darwish SF (2024) The journey of boswellic acids from synthesis to pharmacological activities. Naunyn Schmiedebergs Arch Pharmacol 397(3):1477\u20131504","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"issue":"7","key":"1912_CR72","doi-asserted-by":"publisher","first-page":"1944","DOI":"10.3390\/pharmaceutics15071944","volume":"15","author":"S Ranjbar","year":"2023","unstructured":"Ranjbar S, Emamjomeh A, Sharifi F, Zarepour A, Aghaabbasi K, Dehshahri A, Sepahvand AM, Zarrabi A, Beyzaei H, Zahedi MM (2023) Lipid-based delivery systems for flavonoids and flavonolignans: liposomes, nanoemulsions, and solid lipid nanoparticles. Pharmaceutics 15(7):1944","journal-title":"Pharmaceutics"},{"key":"1912_CR73","doi-asserted-by":"publisher","first-page":"175342592513248","DOI":"10.1177\/17534259251324820","volume":"31","author":"M Riaz","year":"2025","unstructured":"Riaz M, Rasool G, Yousaf R, Fatima H, Munir N, Ejaz H (2025) Anti-rheumatic potential of biological DMARDS and protagonistic role of bio-markers in early detection and management of rheumatoid arthritis. Innate Immun 31:17534259251324820","journal-title":"Innate Immun"},{"issue":"3","key":"1912_CR74","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1111\/cea.12697","volume":"46","author":"N Rumzhum","year":"2016","unstructured":"Rumzhum N, Ammit A (2016) Cyclooxygenase 2: its regulation, role and impact in airway inflammation. Clin Exp Allergy 46(3):397\u2013410","journal-title":"Clin Exp Allergy"},{"issue":"3","key":"1912_CR75","doi-asserted-by":"publisher","first-page":"255","DOI":"10.52711\/2349-2988.2024.00036","volume":"16","author":"RS Sakhare","year":"2024","unstructured":"Sakhare RS, Kulkarni PN, Puskar PV, Bhatane RB, Baramade KN, Vibhute DD (2024) A brief overview of Boswellia serrata a potential herbal treatment for rheumatoid arthritis. Res J Sci Technol 16(3):255\u2013264","journal-title":"Res J Sci Technol"},{"issue":"1","key":"1912_CR76","doi-asserted-by":"publisher","first-page":"1811","DOI":"10.1080\/10717544.2022.2083724","volume":"29","author":"A Salawi","year":"2022","unstructured":"Salawi A (2022) Self-emulsifying drug delivery systems: a novel approach to deliver drugs. Drug Deliv 29(1):1811\u20131823","journal-title":"Drug Deliv"},{"key":"1912_CR77","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.931914","volume":"13","author":"C Sanchez","year":"2022","unstructured":"Sanchez C, Zappia J, Lambert C, Foguenne J, Dierckxsens Y, Dubuc J-E, Delcour J-P, Gothot A, Henrotin Y (2022) Curcuma longa and Boswellia serrata extracts modulate different and complementary pathways on human chondrocytes in vitro: deciphering of a transcriptomic study. Front Pharmacol 13:931914","journal-title":"Front Pharmacol"},{"key":"1912_CR78","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01767-1","author":"T Satapathy","year":"2025","unstructured":"Satapathy T, Minj A, Verma M (2025) Impact of NSAIDs corticosteroids DMARDs biologics and their comparisons with natural products in C-reactive proteins (CRP) linked cardiovascular disorders. Inflammopharmacology. https:\/\/doi.org\/10.1007\/s10787-025-01767-1","journal-title":"Inflammopharmacology"},{"issue":"9","key":"1912_CR79","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/S1063-4584(03)00156-0","volume":"11","author":"A Schuerwegh","year":"2003","unstructured":"Schuerwegh A, Dombrecht E, Stevens W, Van Offel J, Bridts C, De Clerck L (2003) Influence of pro-inflammatory (IL-1\u03b1, IL-6, TNF-\u03b1, IFN-\u03b3) and anti-inflammatory (IL-4) cytokines on chondrocyte function. Osteoarthritis Cartilage 11(9):681\u2013687","journal-title":"Osteoarthritis Cartilage"},{"issue":"6","key":"1912_CR80","doi-asserted-by":"publisher","first-page":"366","DOI":"10.7150\/ijms.7.366","volume":"7","author":"K Sengupta","year":"2010","unstructured":"Sengupta K, Krishnaraju AV, Vishal AA, Mishra A, Trimurtulu G, Sarma KV, Raychaudhuri SK, Raychaudhuri SP (2010) Comparative efficacy and tolerability of 5-Loxin\u00ae and Aflapin\u00ae against osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. Int J Med Sci 7(6):366","journal-title":"Int J Med Sci"},{"key":"1912_CR81","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1007\/s11010-011-0818-1","volume":"354","author":"K Sengupta","year":"2011","unstructured":"Sengupta K, Kolla JN, Krishnaraju AV, Yalamanchili N, Rao CV, Golakoti T, Raychaudhuri S, Raychaudhuri SP (2011) Cellular and molecular mechanisms of anti-inflammatory effect of Aflapin: a novel Boswellia serrata extract. Mol Cell Biochem 354:189\u2013197","journal-title":"Mol Cell Biochem"},{"issue":"2","key":"1912_CR82","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1002\/ca.22980","volume":"31","author":"K Sharif","year":"2018","unstructured":"Sharif K, Sharif A, Jumah F, Oskouian R, Tubbs RS (2018) Rheumatoid arthritis in review: clinical, anatomical, cellular and molecular points of view. Clin Anat 31(2):216\u2013223","journal-title":"Clin Anat"},{"issue":"2","key":"1912_CR83","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1007\/s13318-019-00599-z","volume":"45","author":"T Sharma","year":"2020","unstructured":"Sharma T, Jana S (2020) Investigation of molecular properties that influence the permeability and oral bioavailability of major \u03b2-boswellic acids. Eur J Drug Metab Pharmacokinet 45(2):243\u2013255","journal-title":"Eur J Drug Metab Pharmacokinet"},{"issue":"6","key":"1912_CR84","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1038\/nrd1109","volume":"2","author":"JS Smolen","year":"2003","unstructured":"Smolen JS, Steiner G (2003) Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discov 2(6):473\u2013488","journal-title":"Nat Rev Drug Discov"},{"key":"1912_CR85","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.37080","author":"R Sohail","year":"2023","unstructured":"Sohail R, Mathew M, Patel KK, Reddy SA, Haider Z, Naria M, Habib A, Abdin ZU, Chaudhry WR, Akbar A (2023) Effects of non-steroidal anti-inflammatory drugs (NSAIDs) and gastroprotective NSAIDs on the gastrointestinal tract: a narrative review. Cureus. https:\/\/doi.org\/10.7759\/cureus.37080","journal-title":"Cureus"},{"issue":"1","key":"1912_CR86","doi-asserted-by":"publisher","first-page":"16","DOI":"10.4103\/ijpn.ijpn_71_17","volume":"32","author":"MA Suva","year":"2018","unstructured":"Suva MA, Kheni DB, Sureja VP (2018) Aflapin\u00ae: a novel and selective 5-lipoxygenase inhibitor for arthritis management. Indian J Pain 32(1):16\u201323","journal-title":"Indian J Pain"},{"issue":"4","key":"1912_CR87","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1136\/gutjnl-2019-319300","volume":"69","author":"C-C Szeto","year":"2020","unstructured":"Szeto C-C, Sugano K, Wang J-G, Fujimoto K, Whittle S, Modi GK, Chen C-H, Park J-B, Tam L-S, Vareesangthip K (2020) Non-steroidal anti-inflammatory drug (NSAID) therapy in patients with hypertension, cardiovascular, renal or gastrointestinal comorbidities: joint APAGE\/APLAR\/APSDE\/APSH\/APSN\/PoA recommendations. Gut 69(4):617\u2013629","journal-title":"Gut"},{"issue":"5","key":"1912_CR88","doi-asserted-by":"publisher","first-page":"3127","DOI":"10.4049\/jimmunol.176.5.3127","volume":"176","author":"Y Takada","year":"2006","unstructured":"Takada Y, Ichikawa H, Badmaev V, Aggarwal BB (2006) Acetyl-11-keto-\u03b2-boswellic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing NF-\u03baB and NF-\u03baB-regulated gene expression. J Immunol 176(5):3127\u20133140","journal-title":"J Immunol"},{"issue":"7","key":"1912_CR89","doi-asserted-by":"publisher","first-page":"848","DOI":"10.2174\/0929867330666230502113150","volume":"31","author":"S Tauro","year":"2024","unstructured":"Tauro S, Dhokchawle B, Mohite P, Nahar D, Nadar S, Coutinho E (2024) Natural anticancer agents: their therapeutic potential, challenges and promising outcomes. Curr Med Chem 31(7):848\u2013870","journal-title":"Curr Med Chem"},{"issue":"3","key":"1912_CR90","doi-asserted-by":"publisher","first-page":"187","DOI":"10.2174\/187152006776930891","volume":"6","author":"A Telliez","year":"2006","unstructured":"Telliez A, Furman C, Pommery N, Henichart J-P (2006) Mechanisms leading to COX-2 expression and COX-2 induced tumorigenesis: topical therapeutic strategies targeting COX-2 expression and activity. Anti-Cancer Agents Med Chem 6(3):187\u2013208","journal-title":"Anti-Cancer Agents Med Chem"},{"issue":"3","key":"1912_CR91","doi-asserted-by":"publisher","first-page":"850","DOI":"10.3390\/pr13030850","volume":"13","author":"P Todorovi\u0107","year":"2025","unstructured":"Todorovi\u0107 P, Krsti\u0107 Ristivojevi\u0107 M, Jovi\u0107 M, Ivkovi\u0107 \u0110, Nestorovi\u0107 \u017divkovi\u0107 J, Ga\u0161i\u0107 U, Dimki\u0107 I, Stojiljkovi\u0107 I, Ristivojevi\u0107 P (2025) Antimicrobial effect of Boswellia serrata resin\u2019s methanolic extracts against skin infection pathogens. Processes 13(3):850","journal-title":"Processes"},{"key":"1912_CR92","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2025.02.016","author":"R Upadhyay","year":"2025","unstructured":"Upadhyay R, Elguindy ANM, Salts L, Donovan K, Sengupta S, Wang K, Giglio P, Chao S, Chakravarti A, Singh R (2025) Boswellia serrata for cerebral radiation necrosis after radiosurgery for brain metastases. Int J Radiat Oncol Biol Phys. https:\/\/doi.org\/10.1016\/j.ijrobp.2025.02.016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"1912_CR93","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1007\/s11095-025-03818-2","volume":"42","author":"N Vaidya","year":"2025","unstructured":"Vaidya N, Agarwal R, Dipankar D, Patkar H, Ganu G, Nagore D, Godse C, Mehta A, Mehta D, Nair S (2025) Efficacy and Safety of Boswellia serrata and Apium graveolens L. extract against knee osteoarthritis and cartilage degeneration: a randomized, double-blind, multicenter, placebo-controlled clinical trial. Pharmaceutical Res 42:249\u2013269","journal-title":"Pharmaceutical Res"},{"issue":"1","key":"1912_CR94","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1080\/14656566.2023.2297798","volume":"25","author":"AI Venetsanopoulou","year":"2024","unstructured":"Venetsanopoulou AI, Voulgari PV, Drosos AA (2024) Advances in non-biological drugs for the treatment of rheumatoid arthritis. Expert Opin Pharmacother 25(1):45\u201353","journal-title":"Expert Opin Pharmacother"},{"issue":"2","key":"1912_CR95","doi-asserted-by":"publisher","first-page":"746","DOI":"10.1007\/s12033-024-01089-7","volume":"67","author":"M Verma","year":"2025","unstructured":"Verma M, Fatima S, Saeed M, Ansari IA (2025) Anti-proliferative, pro-apoptotic, and chemosensitizing potential of 3-acetyl-11-keto-\u03b2-boswellic acid (AKBA) against prostate cancer cells. Mol Biotechnol 67(2):746\u2013761","journal-title":"Mol Biotechnol"},{"issue":"6","key":"1912_CR96","doi-asserted-by":"publisher","first-page":"1153","DOI":"10.3390\/antiox11061153","volume":"11","author":"X Wang","year":"2022","unstructured":"Wang X, Fan D, Cao X, Ye Q, Wang Q, Zhang M, Xiao C (2022) The role of reactive oxygen species in the rheumatoid arthritis-associated synovial microenvironment. Antioxidants 11(6):1153","journal-title":"Antioxidants"},{"key":"1912_CR97","doi-asserted-by":"publisher","first-page":"1371461","DOI":"10.3389\/fmed.2024.1371461","volume":"11","author":"X Wang","year":"2024","unstructured":"Wang X, Kong Y, Li Z (2024) Advantages of Chinese herbal medicine in treating rheumatoid arthritis: a focus on its anti-inflammatory and anti-oxidative effects. Front Med (Lausanne) 11:1371461","journal-title":"Front Med (Lausanne)"},{"key":"1912_CR98","doi-asserted-by":"publisher","first-page":"1159","DOI":"10.1007\/s00228-014-1734-6","volume":"70","author":"M Wehling","year":"2014","unstructured":"Wehling M (2014) Non-steroidal anti-inflammatory drug use in chronic pain conditions with special emphasis on the elderly and patients with relevant comorbidities: management and mitigation of risks and adverse effects. Eur J Clin Pharmacol 70:1159\u20131172","journal-title":"Eur J Clin Pharmacol"},{"issue":"2","key":"1912_CR99","doi-asserted-by":"publisher","first-page":"686","DOI":"10.3390\/ijms22020686","volume":"22","author":"C-Y Wu","year":"2021","unstructured":"Wu C-Y, Yang H-Y, Luo S-F, Lai J-H (2021) From rheumatoid factor to anti-citrullinated protein antibodies and anti-carbamylated protein antibodies for diagnosis and prognosis prediction in patients with rheumatoid arthritis. Int J Mol Sci 22(2):686","journal-title":"Int J Mol Sci"},{"issue":"2","key":"1912_CR100","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1177\/19476035231169940","volume":"15","author":"X Wu","year":"2024","unstructured":"Wu X, Sun AR, Crawford R, Xiao Y, Wang Y, Prasadam I, Mao X (2024) Inhibition of leukotriene A4 hydrolase suppressed cartilage degradation and synovial inflammation in a mouse model of experimental osteoarthritis. Cartilage 15(2):184\u2013194","journal-title":"Cartilage"},{"issue":"2","key":"1912_CR101","doi-asserted-by":"publisher","first-page":"225","DOI":"10.3109\/14397595.2013.854056","volume":"24","author":"B Yousefi","year":"2014","unstructured":"Yousefi B, Jadidi-Niaragh F, Azizi G, Hajighasemi F, Mirshafiey A (2014) The role of leukotrienes in immunopathogenesis of rheumatoid arthritis. Mod Rheumatol 24(2):225\u2013235","journal-title":"Mod Rheumatol"},{"issue":"1","key":"1912_CR102","doi-asserted-by":"publisher","first-page":"12","DOI":"10.15386\/mpr-1422","volume":"93","author":"O-M Zahan","year":"2020","unstructured":"Zahan O-M, Serban O, Gherman C, Fodor D (2020) The evaluation of oxidative stress in osteoarthritis. Med Pharmacy Rep 93(1):12","journal-title":"Med Pharmacy Rep"},{"issue":"1","key":"1912_CR103","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1186\/1752-153X-7-153","volume":"7","author":"Y Zhang","year":"2013","unstructured":"Zhang Y, Ning Z, Lu C, Zhao S, Wang J, Liu B, Xu X, Liu Y (2013) Triterpenoid resinous metabolites from the genus Boswellia: pharmacological activities and potential species-identifying properties. Chem Cent J 7(1):153","journal-title":"Chem Cent J"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-025-01912-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-025-01912-w\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-025-01912-w.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T05:02:20Z","timestamp":1758085340000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-025-01912-w"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,14]]},"references-count":101,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["1912"],"URL":"https:\/\/doi.org\/10.1007\/s10787-025-01912-w","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,14]]},"assertion":[{"value":"24 July 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 August 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 August 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declared that they do not have any financial or personal conflicts about this work.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not required.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}