{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T19:02:29Z","timestamp":1769799749968,"version":"3.49.0"},"reference-count":97,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1007\/s10787-025-02055-8","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T18:01:33Z","timestamp":1764439293000},"page":"743-761","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Sodium alginate-encapsulated Colchicum nanoparticles attenuate TNF-\u03b1 and NF-\u03baB signaling in macrophages: A novel therapeutic strategy for rheumatoid arthritis"],"prefix":"10.1007","volume":"34","author":[{"given":"Hasan","family":"Ege","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fulya Dal","family":"Yontem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim Sirri","family":"Yuzbasioglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sude Naz","family":"Cataltepe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erdi","family":"Bulus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuf Can","family":"Gercek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yesim Muge","family":"Sahin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeynep Ruya","family":"Ege","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,11,29]]},"reference":[{"key":"2055_CR60","doi-asserted-by":"publisher","first-page":"124474","DOI":"10.1016\/j.ijbiomac.2023.124474","volume":"240","author":"M Abdin","year":"2023","unstructured":"Abdin M, Mabrouk M, El-Sebaiy L, Eissa M, El-Bana M, Salama MA, Naeem MA (2023) Composite films based on carboxy Methyl cellulose and sodium alginate incorporated thymus vulgaris purified leaves extract for food application: assessment, antimicrobial and antioxidant properties. Int J Biol Macromol 240:124474","journal-title":"Int J Biol Macromol"},{"issue":"7","key":"2055_CR52","doi-asserted-by":"publisher","first-page":"3625","DOI":"10.1039\/C8RA09275C","volume":"9","author":"I Ali","year":"2019","unstructured":"Ali I, Peng C, Naz I, Lin D, Saroj DP, Ali M (2019) Development and application of novel bio-magnetic membrane capsules for the removal of the cationic dye malachite green in wastewater treatment. RSC Adv 9(7):3625\u20133646","journal-title":"RSC Adv"},{"issue":"26","key":"2055_CR36","doi-asserted-by":"publisher","first-page":"7970","DOI":"10.1021\/jf048741x","volume":"52","author":"R Apak","year":"2004","unstructured":"Apak R, G\u00fc\u00e7l\u00fc K, Ozy\u00fcrek M, Karademir SE (2004) Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. J Agric Food Chem 52(26):7970\u20137981. https:\/\/doi.org\/10.1021\/jf048741x","journal-title":"J Agric Food Chem"},{"key":"2055_CR47","doi-asserted-by":"crossref","unstructured":"Azeez S, Shenbagaraman R (2025) Fourier transform infrared spectroscopy in characterization of bionanocomposites. Characterization techniques in bionanocomposites. Woodhead Publishing, pp 209\u2013227","DOI":"10.1016\/B978-0-443-22067-8.00008-3"},{"issue":"1","key":"2055_CR46","doi-asserted-by":"publisher","first-page":"108","DOI":"10.2174\/157341113804486455","volume":"9","author":"M Baranska","year":"2013","unstructured":"Baranska M, Roman M, Cz Dobrowolski J, Schulz H, Baranski R (2013) Recent advances in Raman analysis of plants: alkaloids, carotenoids, and polyacetylenes. Curr Anal Chem 9(1):108\u2013127","journal-title":"Curr Anal Chem"},{"key":"2055_CR90","unstructured":"Bello SA (2017) Development and Characterisation of Epoxy-Alumininum-Coconut Shell Particulate Hybrid Nanocomposite for Automobile Applications (Doctoral dissertation, University of Lagos (Nigeria))"},{"issue":"1","key":"2055_CR38","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1002\/jsfa.6706","volume":"95","author":"G Bobo-Garc\u00eda","year":"2015","unstructured":"Bobo-Garc\u00eda G, Davidov\u2010Pardo G, Arroqui C, V\u00edrseda P, Mar\u00edn\u2010Arroyo MR, Navarro M (2015) Intra\u2010laboratory validation of microplate methods for total phenolic content and antioxidant activity on polyphenolic extracts, and comparison with conventional spectrophotometric methods. J Sci Food Agric 95(1):204\u2013209","journal-title":"J Sci Food Agric"},{"key":"2055_CR85","doi-asserted-by":"crossref","unstructured":"Bordim KAQ, Carvalho J\u00fanior JAB, Ramos VS, Tavares MIB (2025) Nanoencapsulation of creatine: unlocking hydrophilic bioactive potential through double emulsification by solvent diffusion. J Appl Polym Sci, 142(4), e56411","DOI":"10.1002\/app.56411"},{"issue":"8","key":"2055_CR26","doi-asserted-by":"publisher","first-page":"e161600","DOI":"10.1172\/JCI161600","volume":"132","author":"FM Brennan","year":"2022","unstructured":"Brennan FM, McInnes IB (2022) Evidence that cytokines play a role in rheumatoid arthritis. J Clin Invest 132(8):e161600. https:\/\/doi.org\/10.1172\/JCI161600","journal-title":"J Clin Invest"},{"key":"2055_CR31","unstructured":"Brickell CD (1984) Colchicum L. In: Davis, P.H. (ed.). Flora of Turkey and the East Aegean Islands 8, 329\u2013351. Edinburgh University Press"},{"issue":"3","key":"2055_CR34","first-page":"178","volume":"10","author":"CC Chang","year":"2002","unstructured":"Chang CC, Yang MH, Wen HM, Chern JC (2002) Estimation of total flavonoid content in propolis by two complementary colorimetric methods. J Food Drug Anal 10(3):178\u2013182","journal-title":"J Food Drug Anal"},{"issue":"5","key":"2055_CR73","doi-asserted-by":"publisher","first-page":"631","DOI":"10.3390\/pharmaceutics13050631","volume":"13","author":"AP Chiriac","year":"2021","unstructured":"Chiriac AP, Rusu AG, Nita LE, Chiriac VM, Neamtu I, Sandu A (2021) Polymeric carriers designed for encapsulation of essential oils with biological activity. Pharmaceutics 13(5):631","journal-title":"Pharmaceutics"},{"key":"2055_CR25","doi-asserted-by":"publisher","first-page":"175628482311528","DOI":"10.1177\/175628482311528","volume":"16","author":"R Conway","year":"2023","unstructured":"Conway R, Carey JJ (2023) Risk of liver disease in methotrexate treated patients. Therapeutic Adv Gastroenterol 16:175628482311528. https:\/\/doi.org\/10.1177\/175628482311528","journal-title":"Therapeutic Adv Gastroenterol"},{"issue":"3","key":"2055_CR24","doi-asserted-by":"publisher","first-page":"145","DOI":"10.1038\/s41584-020-0373-9","volume":"16","author":"BN Cronstein","year":"2020","unstructured":"Cronstein BN, Aune TM (2020) Methotrexate and its mechanisms of action in inflammatory arthritis. Nat Rev Rheumatol 16(3):145\u2013154. https:\/\/doi.org\/10.1038\/s41584-020-0373-9","journal-title":"Nat Rev Rheumatol"},{"issue":"4","key":"2055_CR5","doi-asserted-by":"publisher","first-page":"590","DOI":"10.1093\/rheumatology\/kes329","volume":"52","author":"JL Davignon","year":"2013","unstructured":"Davignon JL, Hayder M, Baron M, Boyer JF, Constantin A, Apparailly F, Cantagrel A (2013) Targeting monocytes\/macrophages in the treatment of rheumatoid arthritis. Rheumatology 52(4):590\u2013598. https:\/\/doi.org\/10.1093\/rheumatology\/kes329","journal-title":"Rheumatology"},{"issue":"7","key":"2055_CR53","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1007\/s10008-021-04985-z","volume":"25","author":"MI Diana","year":"2021","unstructured":"Diana MI, Selvin PC, Selvasekarapandian S, Krishna MV (2021) Investigations on Na-ion conducting electrolyte based on sodium alginate biopolymer for all-solid-state sodium-ion batteries. J Solid State Electrochem 25(7):2009\u20132020","journal-title":"J Solid State Electrochem"},{"issue":"22","key":"2055_CR93","doi-asserted-by":"publisher","first-page":"2100809","DOI":"10.1002\/admi.202100809","volume":"8","author":"A Dodero","year":"2021","unstructured":"Dodero A, Alberti S, Gaggero G, Ferretti M, Botter R, Vicini S, Castellano M (2021) An up-to\u2010date review on alginate nanoparticles and nanofibers for biomedical and pharmaceutical applications. Adv Mater Interfaces 8(22):2100809","journal-title":"Adv Mater Interfaces"},{"issue":"13","key":"2055_CR86","doi-asserted-by":"publisher","first-page":"3984","DOI":"10.3390\/molecules26133984","volume":"26","author":"R Dom\u00ednguez","year":"2021","unstructured":"Dom\u00ednguez R, Pateiro M, Munekata PE, McClements DJ, Lorenzo JM (2021) Encapsulation of bioactive phytochemicals in plant-based matrices and application as additives in meat and meat products. Molecules 26(13):3984","journal-title":"Molecules"},{"key":"2055_CR32","unstructured":"Dusen O, Gurcan B (2018) Colchicum L. In: Guner, A., Kandemir, A., Menemen, Y., Yildirim, H., Aslan, S., Eksi, G., Guner, I. & Cimen, A.O. (eds.). Illustrated Flora of Turkey 2, 688\u2013776. ANG Foundation Nezahat Gokyigit Botanical Garden Publications"},{"key":"2055_CR88","unstructured":"Ebaye Bejor S (2020) Effect of particle size distribution on kinetics and overall degradation in anaerobic digestion of waste biomass (Doctoral dissertation, University of Sheffield)"},{"key":"2055_CR54","doi-asserted-by":"publisher","first-page":"108258","DOI":"10.1016\/j.polymertesting.2023.108258","volume":"129","author":"HG El Gohary","year":"2023","unstructured":"El Gohary HG, Asnag GM, Tarabiah AE, Qahtan TF, Abdelrazek EM, Cevik E, Saeed A (2023) Modification and development of optical, thermal, dielectric properties and antibacterial activity of PVA\/SA blend by Ag\/Se nanofillers: nanocomposites for energy storage devices and food packaging applications. Polym Test 129:108258","journal-title":"Polym Test"},{"issue":"712","key":"2055_CR20","doi-asserted-by":"publisher","first-page":"eabq2180","DOI":"10.1126\/scitranslmed.abq2180","volume":"15","author":"Q Feng","year":"2023","unstructured":"Feng Q, Sun J, Jiang X (2023) Nanomedicine for inflammatory diseases: from bench to bedside. Sci Transl Med 15(712):eabq2180. https:\/\/doi.org\/10.1126\/scitranslmed.abq2180","journal-title":"Sci Transl Med"},{"key":"2055_CR92","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1007\/978-3-031-31380-6_12","volume-title":"Pharmaceutical process engineering and scale-up principles","author":"C Fernandes","year":"2023","unstructured":"Fernandes C, Jathar M, Sawant BKS, Warde T (2023) Scale-up of nanoparticle manufacturing process. Pharmaceutical process engineering and scale-up principles. Springer Nature Switzerland, Cham, pp 173\u2013203"},{"issue":"7","key":"2055_CR15","doi-asserted-by":"publisher","first-page":"1108","DOI":"10.1002\/art.41752","volume":"73","author":"L Fraenkel","year":"2021","unstructured":"Fraenkel L, Bathon JM, England BR, St. Clair EW, Arayssi T, Carandang K, Akl EA (2021) 2021 American college of rheumatology guideline for the treatment of rheumatoid arthritis. Arthritis Rheumatol 73(7):1108\u20131123. https:\/\/doi.org\/10.1002\/art.41752","journal-title":"Arthritis Rheumatol"},{"issue":"6","key":"2055_CR100","doi-asserted-by":"publisher","first-page":"1636","DOI":"10.1016\/j.jaad.2021.02.019","volume":"84","author":"JM Gelfand","year":"2021","unstructured":"Gelfand JM, Wan J, Zhang H, Shin DB, Ogdie A, Syed MN,  Egeberg A (2021) Risk of liver disease in patients withpsoriasis, psoriatic arthritis, and rheumatoid arthritis receiving methotrexate: A population-based study. J Am Acad Dermatol 84(6):1636\u20131643","journal-title":"J Am Acad Dermatol"},{"issue":"12","key":"2055_CR39","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.3390\/antiox13121483","volume":"13","author":"YC Gercek","year":"2024","unstructured":"Gercek YC, Dagsuyu E, Basturk FN, K\u0131rk\u0131nc\u0131 S, Y\u0131ld\u0131r\u0131m N, K\u0131skan\u00e7 G, Kosti\u0107 A\u017d (2024) Enzyme Inhibitory, Physicochemical, and phytochemical properties and botanical sources of Honey, bee Pollen, bee Bread, and propolis obtained from the same apiary. Antioxidants 13(12):1483. https:\/\/doi.org\/10.3390\/antiox13121483","journal-title":"Antioxidants"},{"issue":"5","key":"2055_CR18","doi-asserted-by":"publisher","first-page":"921","DOI":"10.3390\/pharmaceutics14050921","volume":"14","author":"M G\u00f3mez-Garc\u00eda","year":"2022","unstructured":"G\u00f3mez-Garc\u00eda M, Melero A, Ruiz-Caro R, Veiga MD (2022) Nanoparticles for the treatment of inflammatory arthritis: a systematic review. Pharmaceutics 14(5):921. https:\/\/doi.org\/10.3390\/pharmaceutics14050921","journal-title":"Pharmaceutics"},{"issue":"4","key":"2055_CR89","doi-asserted-by":"publisher","first-page":"965","DOI":"10.3390\/en17040965","volume":"17","author":"M Gruszczy\u0144ski","year":"2024","unstructured":"Gruszczy\u0144ski M, Ka\u0142u\u017ca T, Mazurkiewicz J, Zawadzki P, Pawlak M, Matz R, Czeka\u0142a W (2024) Preparation of samples for the study of rheological parameters of digested pulps in a bioreactor of an agricultural biogas plant. Energies 17(4):965","journal-title":"Energies"},{"key":"2055_CR79","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.energy.2017.06.022","volume":"134","author":"K Haddad","year":"2017","unstructured":"Haddad K, Jeguirim M, Jellali S, Guizani C, Delmotte L, Bennici S, Limousy L (2017) Combined NMR structural characterization and thermogravimetric analyses for the assessment of the AAEM effect during lignocellulosic biomass pyrolysis. Energy 134:10\u201323","journal-title":"Energy"},{"issue":"5","key":"2055_CR80","doi-asserted-by":"publisher","first-page":"2825","DOI":"10.1002\/app.31736","volume":"116","author":"AA Haroun","year":"2010","unstructured":"Haroun AA, El Toumy SA (2010) Effect of natural polyphenols on physicochemical properties of crosslinked gelatin-based polymeric biocomposite. J Appl Polym Sci 116(5):2825\u20132832","journal-title":"J Appl Polym Sci"},{"issue":"1","key":"2055_CR40","first-page":"3137167","volume":"2018","author":"E Henao","year":"2018","unstructured":"Henao E, Delgado E, Contreras H, Quintana G (2018) Polyelectrolyte complexation versus ionotropic gelation for chitosan-based hydrogels with carboxymethylcellulose, carboxymethyl starch, and alginic acid. Int J Chem Eng 2018(1):3137167","journal-title":"Int J Chem Eng"},{"key":"2055_CR6","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.biomaterials.2017.03.044","volume":"131","author":"R Heo","year":"2017","unstructured":"Heo R, You DG, Um W, Choi KY, Jeon S, Park JS, Park JH (2017) Dextran sulfate nanoparticles as a theranostic nanomedicine for rheumatoid arthritis. Biomaterials 131:15\u201326. https:\/\/doi.org\/10.1016\/j.biomaterials.2017.03.044","journal-title":"Biomaterials"},{"key":"2055_CR56","doi-asserted-by":"crossref","unstructured":"Hu X, Dou J, Min R, Liu L, Meng Z (2025) Modulation of physicochemical properties and cooking stability in plant-based spherical egg yolk encapsulated in sodium alginate-gellan gum-chitosan composite films. Carbohydr Polym, 124276","DOI":"10.1016\/j.carbpol.2025.124276"},{"key":"2055_CR67","unstructured":"Ibrahim TA (2023) Effect of extraction solvents and encapsulation on the efficacy of certain medicinal plant extracts to inhibit enteric methane emission (Doctoral dissertation, University of Pretoria (South Africa))"},{"key":"2055_CR84","doi-asserted-by":"publisher","first-page":"100077","DOI":"10.1016\/j.addlet.2022.100077","volume":"3","author":"SF Islam","year":"2022","unstructured":"Islam SF, Hawkins SM, Meyer JL, Sharman AR (2022) Evaluation of different particle size distribution and morphology characterization techniques. Additive Manuf Lett 3:100077","journal-title":"Additive Manuf Lett"},{"key":"2055_CR43","doi-asserted-by":"crossref","unstructured":"Jana S, Trivedi MK, Tallapragada RM, Branton A, Trivedi D, Nayak G, Mishra R (2015) Characterization of physicochemical and thermal properties of Chitosan and sodium alginate after biofield treatment. Pharm Anal Acta, 6(10)","DOI":"10.4172\/2153-2435.1000430"},{"issue":"2","key":"2055_CR16","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1093\/rheumatology\/keac421","volume":"62","author":"M Jani","year":"2023","unstructured":"Jani M, Chinoy H, Warren RB, Griffiths CE, Plant D (2023) Clinical utility of random anti-drug antibody level measurement in patients on adalimumab. Rheumatology 62(2):789\u2013797. https:\/\/doi.org\/10.1093\/rheumatology\/keac421","journal-title":"Rheumatology"},{"issue":"Suppl 1","key":"2055_CR14","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1136\/annrheumdis-2022-eular.2764","volume":"81","author":"S Jin","year":"2022","unstructured":"Jin S, Li M, Fang Y, Zhang Q, Liu J, Duan Y, Sun X (2022) Global burden of rheumatoid arthritis in 204 countries and territories from 1990 to 2019. Ann Rheum Dis 81(Suppl 1):58\u201359. https:\/\/doi.org\/10.1136\/annrheumdis-2022-eular.2764","journal-title":"Ann Rheum Dis"},{"key":"2055_CR65","first-page":"101038","volume":"15","author":"PM Junaid","year":"2024","unstructured":"Junaid PM, Dar AH, Dash KK, Rohilla S, Islam RU, Shams R, Zaidi S (2024) Polysaccharide-based hydrogels for microencapsulation of bioactive compounds: a review. J Agric Food Res 15:101038","journal-title":"J Agric Food Res"},{"issue":"1","key":"2055_CR27","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1038\/s41584-022-00872-7","volume":"19","author":"J Kay","year":"2023","unstructured":"Kay J, Upchurch KS, Aletaha D (2023) Immunogenicity of biologic therapies in rheumatoid arthritis: current concepts. Nat Rev Rheumatol 19(1):43\u201355. https:\/\/doi.org\/10.1038\/s41584-022-00872-7","journal-title":"Nat Rev Rheumatol"},{"key":"2055_CR21","doi-asserted-by":"publisher","first-page":"114300","DOI":"10.1016\/j.addr.2022.114300","volume":"185","author":"C Kelly","year":"2022","unstructured":"Kelly C, Jefferies C, Cryan SA (2022) Targeted therapies for rheumatoid arthritis: nanomedicine approaches. Adv Drug Deliv Rev 185:114300. https:\/\/doi.org\/10.1016\/j.addr.2022.114300","journal-title":"Adv Drug Deliv Rev"},{"key":"2055_CR35","doi-asserted-by":"publisher","first-page":"129310","DOI":"10.1016\/j.foodchem.2021.129310","volume":"351","author":"A\u017d Kosti\u0107","year":"2021","unstructured":"Kosti\u0107 A\u017d, Milin\u010di\u0107 DD, Stanisavljevi\u0107 NS, Ga\u0161i\u0107 UM, Levi\u0107 S, Koji\u0107 MO, Pe\u0161i\u0107 MB (2021) Polyphenol bioaccessibility and antioxidant properties of in vitro digested spray-dried thermally-treated skimmed goat milk enriched with pollen. Food Chem 351:129310","journal-title":"Food Chem"},{"key":"2055_CR3","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jaut.2014.01.027","volume":"48","author":"M Kourilovitch","year":"2014","unstructured":"Kourilovitch M, Galarza-Maldonado C, Ortiz-Prado E (2014) Diagnosis and classification of rheumatoid arthritis. J Autoimmun 48:26\u201330. https:\/\/doi.org\/10.1016\/j.jaut.2014.01.027","journal-title":"J Autoimmun"},{"key":"2055_CR95","doi-asserted-by":"crossref","unstructured":"Lai J, Azad AK, Sulaiman WMAW, Kumarasamy V, Subramaniyan V, Alshehade SA (2024) Alginate-based encapsulation fabrication technique for drug delivery: an updated review of particle type, formulation technique, pharmaceutical ingredient, and targeted delivery system. Pharmaceutics, 16(3), 3yousef70","DOI":"10.3390\/pharmaceutics16030370"},{"issue":"3","key":"2055_CR30","doi-asserted-by":"publisher","first-page":"138565","DOI":"10.1016\/j.cej.2022.138565","volume":"451","author":"J Li","year":"2023","unstructured":"Li J, Zhang Y, Chen Y, Liu Y, Wang J (2023) Alginate-based nanomaterials: fabrication techniques, properties, and applications. Chem Eng J 451(3):138565. https:\/\/doi.org\/10.1016\/j.cej.2022.138565","journal-title":"Chem Eng J"},{"key":"2055_CR76","first-page":"101566","volume":"23","author":"C Li","year":"2024","unstructured":"Li C, Wu Y, Zhu Q, Xie C, Yan Y (2024) Alterations in physico-chemical properties, microstructure, sensory characteristics, and volatile compounds of red pepper (Capsicum annuum var. conoides) during various thermal drying durations. Food Chemistry: X 23:101566","journal-title":"Food Chemistry: X"},{"issue":"9","key":"2055_CR61","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.3390\/coatings13091487","volume":"13","author":"AI Lopes","year":"2023","unstructured":"Lopes AI, Melo A, Caleja C, Pereira E, Finimundy TC, Afonso TB, Pintado M (2023) Evaluation of antimicrobial and antioxidant activities of alginate edible coatings incorporated with plant extracts. Coatings 13(9):1487","journal-title":"Coatings"},{"issue":"21","key":"2055_CR66","doi-asserted-by":"publisher","first-page":"4759","DOI":"10.3390\/polym14214759","volume":"14","author":"AR Machado","year":"2022","unstructured":"Machado AR, Silva PM, Vicente AA, Souza-Soares LA, Pinheiro AC, Cerqueira MA (2022) Alginate particles for encapsulation of phenolic extract from spirulina sp. LEB-18: physicochemical characterization and assessment of in vitro Gastrointestinal behavior. Polymers 14(21):4759","journal-title":"Polymers"},{"issue":"23","key":"2055_CR49","doi-asserted-by":"publisher","first-page":"8334","DOI":"10.3390\/molecules27238334","volume":"27","author":"CRA Mahl","year":"2022","unstructured":"Mahl CRA, Bataglioli RA, Calais GB, Taketa TB, Beppu MM (2022) Role of alginate composition on copper ion uptake in the presence of histidine or Beta-amyloid. Molecules 27(23):8334","journal-title":"Molecules"},{"key":"2055_CR62","doi-asserted-by":"publisher","first-page":"554597","DOI":"10.3389\/fcvm.2020.554597","volume":"7","author":"QA Majid","year":"2020","unstructured":"Majid QA, Fricker AT, Gregory DA, Davidenko N, Cruz H, Jabbour O, Roy RJ, I (2020) Natural biomaterials for cardiac tissue engineering: a highly biocompatible solution. Front Cardiovasc Med 7:554597","journal-title":"Front Cardiovasc Med"},{"issue":"5","key":"2055_CR57","doi-asserted-by":"publisher","first-page":"626","DOI":"10.1016\/j.bjp.2018.07.001","volume":"28","author":"LC Malucelli","year":"2018","unstructured":"Malucelli LC, Massulo T, Magalh\u00e3es WL, Stofella NC, Vasconcelos EC, Filho MASC, Murakami FS (2018) Thermal and chemical characterization of Dicksonia Sellowiana extract by means of thermal analysis. Revista Brasileira De Farmacognosia 28(5):626\u2013630","journal-title":"Revista Brasileira De Farmacognosia"},{"issue":"10","key":"2055_CR10","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/j.autrev.2011.04.020","volume":"10","author":"A Marrelli","year":"2011","unstructured":"Marrelli A, Cipriani P, Liakouli V, Carubbi F, Perricone C, Perricone R, Giacomelli R (2011) Angiogenesis in rheumatoid arthritis: a disease specific process or a common response to chronic inflammation? Autoimmun Rev 10(10):595\u2013598. https:\/\/doi.org\/10.1016\/j.autrev.2011.04.020","journal-title":"Autoimmun Rev"},{"issue":"8","key":"2055_CR1","doi-asserted-by":"publisher","first-page":"917","DOI":"10.14670\/HH-22.917","volume":"22","author":"N Maruotti","year":"2007","unstructured":"Maruotti N, Cantatore FP, Crivellato E, Vacca A, Ribatti D (2007) Macrophages in rheumatoid arthritis. Histol Histopathol 22(8):917\u2013926. https:\/\/doi.org\/10.14670\/HH-22.917","journal-title":"Histol Histopathol"},{"issue":"6","key":"2055_CR7","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1038\/nri2094","volume":"7","author":"IB McInnes","year":"2007","unstructured":"McInnes IB, Schett G (2007) Cytokines in the pathogenesis of rheumatoid arthritis. Nat Rev Immunol 7(6):429\u2013442. https:\/\/doi.org\/10.1038\/nri2094","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"2055_CR19","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1038\/s41573-020-0090-8","volume":"20","author":"MJ Mitchell","year":"2021","unstructured":"Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R (2021) Engineering precision nanoparticles for drug delivery. Nat Rev Drug Discovery 20(2):101\u2013124. https:\/\/doi.org\/10.1038\/s41573-020-0090-8","journal-title":"Nat Rev Drug Discovery"},{"issue":"1","key":"2055_CR55","doi-asserted-by":"publisher","first-page":"176","DOI":"10.3390\/polym12010176","volume":"12","author":"R Mohammadinejad","year":"2020","unstructured":"Mohammadinejad R, Kumar A, Ranjbar-Mohammadi M, Ashrafizadeh M, Han SS, Khang G, Roveimiab Z (2020) Recent advances in natural gum-based biomaterials for tissue engineering and regenerative medicine: a review. Polymers 12(1):176","journal-title":"Polymers"},{"key":"2055_CR42","doi-asserted-by":"publisher","first-page":"110500","DOI":"10.1016\/j.radphyschem.2022.110500","volume":"202","author":"MZ Mollah","year":"2023","unstructured":"Mollah MZ, Faruque MR, Bradley DA, Khandaker MU, Assaf A, S (2023) FTIR and rheology study of alginate samples: effect of radiation. Radiat Phys Chem 202:110500","journal-title":"Radiat Phys Chem"},{"issue":"1","key":"2055_CR68","doi-asserted-by":"publisher","first-page":"28","DOI":"10.3390\/polym12010028","volume":"12","author":"SB Munteanu","year":"2019","unstructured":"Munteanu SB, Vasile C (2019) Vegetable additives in food packaging polymeric materials. Polymers 12(1):28","journal-title":"Polymers"},{"issue":"1","key":"2055_CR81","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1002\/jsfa.11512","volume":"102","author":"D Nishimoto-Sauceda","year":"2022","unstructured":"Nishimoto-Sauceda D, Romero\u2010Robles LE, Antunes\u2010Ricardo M (2022) Biopolymer nanoparticles: a strategy to enhance stability, bioavailability, and biological effects of phenolic compounds as functional ingredients. J Sci Food Agric 102(1):41\u201352","journal-title":"J Sci Food Agric"},{"issue":"43","key":"2055_CR82","doi-asserted-by":"publisher","first-page":"6233","DOI":"10.1002\/adma.201302737","volume":"25","author":"Y Niu","year":"2013","unstructured":"Niu Y, Yu M, Hartono SB, Yang J, Xu H, Zhang H, Yu C (2013) Nanoparticles mimicking viral surface topography for enhanced cellular delivery. Adv Mater 25(43):6233\u20136237","journal-title":"Adv Mater"},{"key":"2055_CR12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40064-015-0923-9","volume":"4","author":"K Oda","year":"2015","unstructured":"Oda K, Minata M (2015) Drug free remission after steroid-dependent disappearance of lymphoproliferative disorder in rheumatoid arthritis patient treated with TNF-alpha blockade: case study. Springerplus 4:1\u20135. https:\/\/doi.org\/10.1186\/s40064-015-0923-9","journal-title":"Springerplus"},{"issue":"8","key":"2055_CR9","doi-asserted-by":"publisher","first-page":"4489","DOI":"10.1007\/s12274-018-2071-3","volume":"11","author":"IM Oliveira","year":"2018","unstructured":"Oliveira IM, Gon\u00e7alves C, Reis RL, Oliveira JM (2018) Engineering nanoparticles for targeting rheumatoid arthritis: Past, present, and future trends. Nano Res 11(8):4489\u20134506. https:\/\/doi.org\/10.1007\/s12274-018-2071-3","journal-title":"Nano Res"},{"key":"2055_CR22","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.jconrel.2020.12.013","volume":"330","author":"S Panda","year":"2021","unstructured":"Panda S, Kumar S, Kumar N (2021) Drug delivery innovations for rheumatoid arthritis treatment. J Controlled Release 330:119\u2013134. https:\/\/doi.org\/10.1016\/j.jconrel.2020.12.013","journal-title":"J Controlled Release"},{"issue":"4","key":"2055_CR48","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1016\/j.carres.2009.12.010","volume":"345","author":"SK Papageorgiou","year":"2010","unstructured":"Papageorgiou SK, Kouvelos EP, Favvas EP, Sapalidis AA, Romanos GE, Katsaros FK (2010) Metal\u2013carboxylate interactions in metal\u2013alginate complexes studied with FTIR spectroscopy. Carbohydr Res 345(4):469\u2013473","journal-title":"Carbohydr Res"},{"issue":"1","key":"2055_CR50","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1007\/s12541-018-0015-1","volume":"19","author":"SY Park","year":"2018","unstructured":"Park SY, Kim WJ, Choi JB, Kim S (2018) Physical and mechanical properties of alginate-based hydrogel film as carrier for release of acetylthiocholine. Int J Precis Eng Manuf 19(1):129\u2013135","journal-title":"Int J Precis Eng Manuf"},{"issue":"3","key":"2055_CR45","doi-asserted-by":"publisher","first-page":"684","DOI":"10.3390\/molecules30030684","volume":"30","author":"S Pasieczna-Patkowska","year":"2025","unstructured":"Pasieczna-Patkowska S, Cichy M, Flieger J (2025) Application of fourier transform infrared (FTIR) spectroscopy in characterization of green synthesized nanoparticles. Molecules 30(3):684","journal-title":"Molecules"},{"issue":"6","key":"2055_CR11","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1002\/wnan.157","volume":"3","author":"CT Pham","year":"2011","unstructured":"Pham CT (2011) Nanotherapeutic approaches for the treatment of rheumatoid arthritis. Wiley Interdisciplinary Reviews: Nanomed Nanobiotechnol 3(6):607\u2013619. https:\/\/doi.org\/10.1002\/wnan.157","journal-title":"Wiley Interdisciplinary Reviews: Nanomed Nanobiotechnol"},{"issue":"5","key":"2055_CR77","doi-asserted-by":"publisher","first-page":"838","DOI":"10.1021\/acsagscitech.2c00113","volume":"2","author":"TV Pinto","year":"2022","unstructured":"Pinto TV, Silva CA, Siquenique S, Learmonth DA (2022) Micro-and nanocarriers for encapsulation of biological plant protection agents: a systematic literature review. ACS Agricultural Sci Technol 2(5):838\u2013857","journal-title":"ACS Agricultural Sci Technol"},{"key":"2055_CR44","doi-asserted-by":"crossref","unstructured":"Puranik A, Taranath TC (2023) FTIR characterization and validation of secondary metabolites in leaf and bark extracts and direct powder of Erinocarpus nimmonii, an endemic plant","DOI":"10.5958\/0974-4517.2023.00008.3"},{"issue":"1\u20132","key":"2055_CR63","doi-asserted-by":"publisher","first-page":"2200100","DOI":"10.1002\/star.202200100","volume":"76","author":"S Qamar","year":"2024","unstructured":"Qamar S, Karim S, Aslam S, Jahangeer M, Nelofer R, Nadeem AA, Bilal M (2024) Alginate-based bio\u2010nanohybrids with unique properties for biomedical applications. Starch\u2010St\u00e4rke 76(1\u20132):2200100","journal-title":"Starch\u2010St\u00e4rke"},{"issue":"9\u201310","key":"2055_CR37","doi-asserted-by":"publisher","first-page":"1231","DOI":"10.1016\/S0891-5849(98)00315-3","volume":"26","author":"R Re","year":"1999","unstructured":"Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med 26(9\u201310):1231\u20131237. https:\/\/doi.org\/10.1016\/S0891-5849(98)00315-3","journal-title":"Free Radic Biol Med"},{"issue":"8","key":"2055_CR96","doi-asserted-by":"publisher","first-page":"996","DOI":"10.3390\/pharmaceutics17080996","volume":"17","author":"I Safdar","year":"2025","unstructured":"Safdar I, Mahmood S, Abdulwahab MK, Noor M, Ge S, Y., Sofian M, Z (2025) Inhalable nanomaterial discoveries for lung cancer therapy: a review. Pharmaceutics 17(8):996","journal-title":"Pharmaceutics"},{"issue":"1","key":"2055_CR64","doi-asserted-by":"publisher","first-page":"8","DOI":"10.3390\/coatings12010008","volume":"12","author":"KA Shiekh","year":"2021","unstructured":"Shiekh KA, Ngiwngam K, Tongdeesoontorn W (2021) Polysaccharide-based active coatings incorporated with bioactive compounds for reducing postharvest losses of fresh fruits. Coatings 12(1):8","journal-title":"Coatings"},{"issue":"9990","key":"2055_CR28","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1016\/S0140-6736(14)61704-9","volume":"386","author":"JA Singh","year":"2022","unstructured":"Singh JA, Cameron C, Noorbaloochi S, Cullis T, Tucker M, Christensen R, Wells GA (2022) Risk of serious infection in biological treatment of patients with rheumatoid arthritis: a systematic review and meta-analysis. Lancet 386(9990):258\u2013265. https:\/\/doi.org\/10.1016\/S0140-6736(14)61704-9","journal-title":"Lancet"},{"key":"2055_CR33","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/S0076-6879(99)99017-1","volume":"299","author":"VL Singleton","year":"1999","unstructured":"Singleton VL, Orthofer R, Lamuela-Ravent\u00f3s RM (1999) Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Methods Enzymol 299:152\u2013178. https:\/\/doi.org\/10.1016\/S0076-6879(99)99017-1","journal-title":"Methods Enzymol"},{"issue":"7","key":"2055_CR58","doi-asserted-by":"publisher","first-page":"567","DOI":"10.2174\/1389557514666140722083034","volume":"14","author":"A Smeriglio","year":"2014","unstructured":"Smeriglio A, Monteleone D, Trombetta D (2014) Health effects of vaccinium myrtillus L.: evaluation of efficacy and technological strategies for preservation of active ingredients. Mini Rev Med Chem 14(7):567\u2013584","journal-title":"Mini Rev Med Chem"},{"issue":"6","key":"2055_CR2","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1038\/nrd1109","volume":"2","author":"JS Smolen","year":"2003","unstructured":"Smolen JS, Steiner G (2003) Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discovery 2(6):473\u2013488. https:\/\/doi.org\/10.1038\/nrd1109","journal-title":"Nat Rev Drug Discovery"},{"issue":"1","key":"2055_CR13","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1136\/ard-2022-223356","volume":"82","author":"JS Smolen","year":"2020","unstructured":"Smolen JS, Landew\u00e9 RB, Bergstra SA, Kerschbaumer A, Sepriano A, Aletaha D, van der Heijde D (2020) EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update. Ann Rheum Dis 82(1):3\u201318. https:\/\/doi.org\/10.1136\/ard-2022-223356","journal-title":"Ann Rheum Dis"},{"issue":"2","key":"2055_CR78","doi-asserted-by":"publisher","first-page":"230","DOI":"10.3390\/pharmaceutics13020230","volume":"13","author":"UG Spizzirri","year":"2021","unstructured":"Spizzirri UG, Aiello F, Carullo G, Facente A, Restuccia D (2021) Nanotechnologies: an innovative tool to release natural extracts with antimicrobial properties. Pharmaceutics 13(2):230","journal-title":"Pharmaceutics"},{"issue":"4","key":"2055_CR17","doi-asserted-by":"publisher","first-page":"3328","DOI":"10.1021\/acsnano.2c11237","volume":"17","author":"GS Sreena","year":"2023","unstructured":"Sreena GS, Nathanael AJ (2023) Nanocarriers in cancer therapy: challenges and opportunities. ACS Nano 17(4):3328\u20133345. https:\/\/doi.org\/10.1021\/acsnano.2c11237","journal-title":"ACS Nano"},{"issue":"8","key":"2055_CR72","doi-asserted-by":"publisher","first-page":"653","DOI":"10.3390\/gels11080653","volume":"11","author":"AI Stancu","year":"2025","unstructured":"Stancu AI, Di\u021bu LM, Oprea E, Ficai A, Badea IA, Buleandr\u0103 M, Mititelu M (2025) New antimicrobial gels based on clove essential Oil\u2013Cyclodextrin complex and plant extracts for topical use. Gels 11(8):653","journal-title":"Gels"},{"key":"2055_CR51","unstructured":"Thakur S (2016) Sodium alginate, Xanthan gum biopolymer composites: synthesis, characterisation and application in organic dye removal from water. University of Johannesburg (South Africa)"},{"key":"2055_CR94","doi-asserted-by":"crossref","unstructured":"Tiong YW (2025) Application of nanomaterial technology in sustainable biogas production. Sustainable structural materials. CRC, pp 18\u201340","DOI":"10.1201\/9781003362227-2"},{"issue":"9","key":"2055_CR70","doi-asserted-by":"publisher","first-page":"2416390","DOI":"10.1002\/adfm.202416390","volume":"35","author":"P Tordi","year":"2025","unstructured":"Tordi P, Ridi F, Samor\u00ec P, Bonini M (2025) Cation-alginate complexes and their hydrogels: a powerful toolkit for the development of next\u2010generation sustainable functional materials. Adv Funct Mater 35(9):2416390","journal-title":"Adv Funct Mater"},{"key":"2055_CR91","doi-asserted-by":"crossref","unstructured":"Ulaeto SB, Pancrecious JK, Rajan R, Rajan TPD, Pai BC (2018) Role of nanodispersoids on corrosion Inhibition behavior of smart polymer nanocomposite coatings. Adv Polym Mater Sustain Innovations, 303\u2013348","DOI":"10.1201\/b22326-15"},{"issue":"1","key":"2055_CR83","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3390\/min13010091","volume":"13","author":"U Ulusoy","year":"2023","unstructured":"Ulusoy U (2023) A review of particle shape effects on material properties for various engineering applications: from macro to nanoscale. Minerals 13(1):91","journal-title":"Minerals"},{"issue":"3","key":"2055_CR8","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1038\/nrrheum.2012.237","volume":"9","author":"S Viatte","year":"2013","unstructured":"Viatte S, Plant D, Raychaudhuri S (2013) Genetics and epigenetics of rheumatoid arthritis. Nat Rev Rheumatol 9(3):141\u2013153. https:\/\/doi.org\/10.1038\/nrrheum.2012.237","journal-title":"Nat Rev Rheumatol"},{"issue":"4","key":"2055_CR71","doi-asserted-by":"publisher","first-page":"318","DOI":"10.1080\/10643389.2018.1547621","volume":"49","author":"B Wang","year":"2019","unstructured":"Wang B, Wan Y, Zheng Y, Lee X, Liu T, Yu Z, Gao B (2019) Alginate-based composites for environmental applications: a critical review. Crit Rev Environ Sci Technol 49(4):318\u2013356","journal-title":"Crit Rev Environ Sci Technol"},{"key":"2055_CR29","doi-asserted-by":"publisher","first-page":"114643","DOI":"10.1016\/j.addr.2022.114643","volume":"192","author":"Y Wang","year":"2023","unstructured":"Wang Y, Zhang X, Yu P, Li C (2023) Botanical drug delivery systems for rheumatoid arthritis treatment. Adv Drug Deliv Rev 192:114643. https:\/\/doi.org\/10.1016\/j.addr.2022.114643","journal-title":"Adv Drug Deliv Rev"},{"key":"2055_CR69","doi-asserted-by":"publisher","first-page":"115483","DOI":"10.1016\/j.foodres.2024.115483","volume":"200","author":"H Wang","year":"2025","unstructured":"Wang H, Huang S, Xu X (2025) Calcium alginate reinforced zwitterionic double network hydrogel with mechanical robustness and antimicrobial activity for freshwater shrimp spoilage detection. Food Res Int 200:115483","journal-title":"Food Res Int"},{"issue":"6","key":"2055_CR75","doi-asserted-by":"publisher","first-page":"2782","DOI":"10.1002\/ese3.459","volume":"7","author":"W Xia","year":"2019","unstructured":"Xia W, Xu T, Wang S, Wang H (2019) Mass loss evolution of bituminous fractions at different heating rates and constituent conformation of emitted volatiles. Energy Sci Eng 7(6):2782\u20132796","journal-title":"Energy Sci Eng"},{"issue":"2","key":"2055_CR4","doi-asserted-by":"publisher","first-page":"225","DOI":"10.3109\/14397595.2013.854058","volume":"24","author":"B Yousefi","year":"2014","unstructured":"Yousefi B, Jadidi-Niaragh F, Azizi G, Hajighasemi F, Mirshafiey A (2014) The role of leukotrienes in Immunopathogenesis of rheumatoid arthritis. Mod Rheumatol 24(2):225\u2013235. https:\/\/doi.org\/10.3109\/14397595.2013.854058","journal-title":"Mod Rheumatol"},{"issue":"19","key":"2055_CR74","doi-asserted-by":"publisher","first-page":"4194","DOI":"10.3390\/polym14194194","volume":"14","author":"GL Zabot","year":"2022","unstructured":"Zabot GL, Rodrigues S, Polano Ody F, Vin\u00edcius Tres L, Herrera M, Palacin E, Olivera-Montenegro H, L (2022) Encapsulation of bioactive compounds for food and agricultural applications. Polymers 14(19):4194","journal-title":"Polymers"},{"key":"2055_CR87","doi-asserted-by":"crossref","unstructured":"Zaffar S, Saha S, Agrawal T, Gupta SK, Gulati P, Paul D, Rakshit T (2025) Improved diabetic wound healing via flower extracellular vesicles and Carbon-Dot-Infused Alginate-Polyethylenimine antibacterial hydrogel. ACS Biomaterials Science & Engineering","DOI":"10.1021\/acsbiomaterials.5c00443"},{"key":"2055_CR23","doi-asserted-by":"publisher","first-page":"106614","DOI":"10.1016\/j.phrs.2022.106614","volume":"187","author":"L Zhang","year":"2023","unstructured":"Zhang L, Wang X, Guo J, Xia Q, Zhao W, Zhai G (2023a) Emerging anti-inflammatory natural products for rheumatoid arthritis therapy. Pharmacol Res 187:106614. https:\/\/doi.org\/10.1016\/j.phrs.2022.106614","journal-title":"Pharmacol Res"},{"issue":"19","key":"2055_CR59","doi-asserted-by":"publisher","first-page":"3688","DOI":"10.3390\/foods12193688","volume":"12","author":"W Zhang","year":"2023","unstructured":"Zhang W, Sun J, Li Q, Liu C, Niu F, Yue R, Deng S (2023b) Free radical-mediated grafting of natural polysaccharides such as chitosan, starch, inulin, and pectin with some polyphenols: synthesis, structural characterization, bioactivities, and applications\u2014A review. Foods 12(19):3688","journal-title":"Foods"},{"key":"2055_CR41","doi-asserted-by":"publisher","first-page":"110368","DOI":"10.1016\/j.foodhyd.2024.110368","volume":"156","author":"L Zhang","year":"2024","unstructured":"Zhang L, Shen B, Zheng C, Huang Y, Liang Y, Fei P, Lai W (2024) Chitosan\/oxidized sodium alginate\/Ca2\u2009+\u2009hydrogels: Synthesis, characterization and adsorption properties. Food Hydrocolloids 156:110368","journal-title":"Food Hydrocolloids"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-025-02055-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-025-02055-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-025-02055-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T17:02:50Z","timestamp":1769706170000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-025-02055-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,29]]},"references-count":97,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["2055"],"URL":"https:\/\/doi.org\/10.1007\/s10787-025-02055-8","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,29]]},"assertion":[{"value":"14 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 November 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 November 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}