{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T11:05:57Z","timestamp":1790334357681,"version":"4.1.0"},"reference-count":101,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:00:00Z","timestamp":1790294400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","award":["DST\/WISE-PhD\/LS\/2023\/166"],"award-info":[{"award-number":["DST\/WISE-PhD\/LS\/2023\/166"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Inflammopharmacol"],"DOI":"10.1007\/s10787-026-02407-y","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T10:22:18Z","timestamp":1790331738000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Myrica esculenta fruit extract as a nutraceutical supplement mitigating LPS-induced inflammation through COX-2 and iNOS modulation: integrated in vitro, in vivo, and docking approaches"],"prefix":"10.1007","author":[{"given":"Leena","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manas","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luit M.","family":"Barkalita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Probodh","family":"Borah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananya","family":"Chetia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Momita Rani","family":"Baro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratul","family":"Chakraborty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aashis","family":"Dutta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,25]]},"reference":[{"key":"2407_CR1","doi-asserted-by":"publisher","first-page":"667","DOI":"10.1016\/j.biopha.2018.11.117","volume":"110","author":"AM Abdelrahman","year":"2019","unstructured":"Abdelrahman AM, Suleimani YA, Za\u2019abi MA, Ashique M, Manoj P, Hartmann C, Nemmar A, Schupp N, Ali BH (2019) The reno protective effect of the dipeptidyl peptidase-4 inhibitor sitagliptin on adenine-induced kidney disease in rats. Biomed Pharmacother 110:667\u2013676. https:\/\/doi.org\/10.1016\/j.biopha.2018.11.117","journal-title":"Biomed Pharmacother"},{"issue":"20","key":"2407_CR2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21207675","volume":"21","author":"A Ahuja","year":"2020","unstructured":"Ahuja A, Kim E, Sung GH, Cho JY (2020) STAT3 differentially regulates TLR4-mediated inflammatory responses in early or late phases. Int J Mol Sci 21(20):7675. https:\/\/doi.org\/10.3390\/ijms21207675","journal-title":"Int J Mol Sci"},{"issue":"6","key":"2407_CR3","doi-asserted-by":"publisher","first-page":"383","DOI":"10.2165\/00007256-199928060-00001","volume":"28","author":"LC Almekinders","year":"1999","unstructured":"Almekinders LC (1999) Anti-inflammatory treatment of muscular injuries in sport: an update of recent studies. Sports Med 28(6):383\u2013388. https:\/\/doi.org\/10.2165\/00007256-199928060-00001","journal-title":"Sports Med"},{"key":"2407_CR4","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.freeradbiomed.2019.10.411","volume":"146","author":"S Anavi","year":"2020","unstructured":"Anavi S, Tirosh O (2020) iNOS as a metabolic enzyme under stress conditions. Free Radic Biol Med 146:16\u201335. https:\/\/doi.org\/10.1016\/j.freeradbiomed.2019.10.411","journal-title":"Free Radic Biol Med"},{"key":"2407_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnutbio.2021.108920","volume":"101","author":"JH Azambuja","year":"2022","unstructured":"Azambuja JH, Mancuso RI, Via FID, Torello CO, Saad STO (2022) Protective effect of green tea and epigallocatechin-3-gallate in a LPS-induced systemic inflammation model. J Nutr Biochem 101:108920. https:\/\/doi.org\/10.1016\/j.jnutbio.2021.108920","journal-title":"J Nutr Biochem"},{"key":"2407_CR6","doi-asserted-by":"publisher","first-page":"757","DOI":"10.1016\/j.ijpharm.2016.11.002","volume":"515","author":"W Badri","year":"2016","unstructured":"Badri W, Miladi K, Nazari QA, Greige-Gerges H, Fessi H, Elaissari A (2016) Encapsulation of NSAIDs for inflammation management: overview, progress, challenges and prospects. Int J Pharm 515:757\u2013773. https:\/\/doi.org\/10.1016\/j.ijpharm.2016.11.002","journal-title":"Int J Pharm"},{"issue":"100","key":"2407_CR7","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1159\/000359984","volume":"2014","author":"PJ Barnes","year":"2014","unstructured":"Barnes PJ (2014) Glucocorticoids. Chem. Immunol. Allergy 2014(100):311\u2013316. https:\/\/doi.org\/10.1159\/000359984","journal-title":"Allergy"},{"issue":"1","key":"2407_CR8","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1016\/j.jaci.2016.05.011","volume":"138","author":"PJ Barnes","year":"2016","unstructured":"Barnes PJ (2016) Inflammatory mechanisms in patients with chronic obstructive pulmonary disease. J Allergy Clin Immunol 138(1):16\u201327. https:\/\/doi.org\/10.1016\/j.jaci.2016.05.011","journal-title":"J Allergy Clin Immunol"},{"key":"2407_CR9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2022.116021","volume":"303","author":"MR Baro","year":"2023","unstructured":"Baro MR, Das M, Kalita A, Das B, Sarma K (2023) Exploring the anti-inflammatory potential of Colocasia esculenta root extract in in-vitro and in-vivo models of inflammation. J Ethnopharmacol 303:116021. https:\/\/doi.org\/10.1016\/j.jep.2022.116021","journal-title":"J Ethnopharmacol"},{"key":"2407_CR10","doi-asserted-by":"publisher","first-page":"316","DOI":"10.3389\/fmed.2018.00316","volume":"5","author":"JM Bennett","year":"2018","unstructured":"Bennett JM, Reeves G, Billman GE, Sturmberg JP (2018) Inflammation: nature\u2019s way to efficiently respond to all types of challenges\u2014implications for understanding and managing \u201cthe epidemic\u201d of chronic diseases. Front Med 5:316. https:\/\/doi.org\/10.3389\/fmed.2018.00316","journal-title":"Front Med"},{"key":"2407_CR11","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.1009023","volume":"13","author":"S Bhattacharjee","year":"2022","unstructured":"Bhattacharjee S, Elancheran R, Dutta K, Deb PK, Devi R (2022) Cardioprotective potential of the antioxidant-rich bioactive fraction of Garcinia pedunculata Roxb. ex-Buch. -Ham. against isoproterenol-induced myocardial infarction in Wistar rats. Front Pharmacol 13:1009023. https:\/\/doi.org\/10.3389\/fphar.2022.1009023","journal-title":"Front Pharmacol"},{"issue":"2","key":"2407_CR12","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1002\/path.2287","volume":"1","author":"JR Bradley","year":"2008","unstructured":"Bradley JR (2008) TNF-mediated inflammatory disease. J Pathol 1(2):149\u2013160. https:\/\/doi.org\/10.1002\/path.2287","journal-title":"J Pathol"},{"issue":"1","key":"2407_CR13","doi-asserted-by":"publisher","DOI":"10.1186\/1479-7364-5-1-30","volume":"5","author":"C Brocker","year":"2010","unstructured":"Brocker C, Thompson D, Matsumoto A, Nebert DW, Vasiliou V (2010) Evolutionary divergence and functions of the human interleukin (IL) gene family. Hum Genom 5(1):30. https:\/\/doi.org\/10.1186\/1479-7364-5-1-30","journal-title":"Hum Genom"},{"issue":"5","key":"2407_CR14","doi-asserted-by":"publisher","first-page":"253","DOI":"10.3389\/fimmu.2014.00253","volume":"27","author":"P Chatterjee","year":"2014","unstructured":"Chatterjee P, Chiasson VL, Bounds KR, Mitchell BM (2014) Regulation of the anti- inflammatory cytokines Interleukin-4 and Interleukin-10 during pregnancy. Front Immunol 27(5):253. https:\/\/doi.org\/10.3389\/fimmu.2014.00253","journal-title":"Front Immunol"},{"issue":"6","key":"2407_CR15","doi-asserted-by":"publisher","first-page":"7204","DOI":"10.18632\/oncotarget.23208","volume":"9","author":"L Chen","year":"2017","unstructured":"Chen L, Deng H, Cui H, Fang J, Zuo Z, Deng J, Li Y, Wang X, Zhao L (2017) Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 9(6):7204\u20137218. https:\/\/doi.org\/10.18632\/oncotarget.23208","journal-title":"Oncotarget"},{"issue":"1","key":"2407_CR16","doi-asserted-by":"publisher","first-page":"16","DOI":"10.20307\/nps.2019.25.1.16","volume":"25","author":"J Chun","year":"2019","unstructured":"Chun J, Song K, Kim YS (2019) Anti-inflammatory activity of standardized fraction from Inula helenium L. via suppression of NF-\u03baB pathway in RAW 264.7 cells. Nat Prod Sci 25(1):16\u201322. https:\/\/doi.org\/10.20307\/nps.2019.25.1.16","journal-title":"Nat Prod Sci"},{"issue":"4","key":"2407_CR18","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1111\/j.0022-202X.2005.23856.x","volume":"125","author":"R Clark","year":"2005","unstructured":"Clark R, Kupper T (2005) Old meets new: the interaction between innate and adaptive immunity. J Investig Dermatol 125(4):629\u2013637. https:\/\/doi.org\/10.1111\/j.0022-202X.2005.23856.x","journal-title":"J Investig Dermatol"},{"issue":"4","key":"2407_CR19","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1249\/01.mss.0000210192.49210.fc","volume":"38","author":"PM Clarkson","year":"2006","unstructured":"Clarkson PM, Kearns AK, Rouzier P, Rubin R, Thompson PD (2006) Serum creatine kinase levels and renal function measures in exertional muscle damage. Med Sci Sports Exerc 38(4):623\u2013627. https:\/\/doi.org\/10.1249\/01.mss.0000210192.49210.fc","journal-title":"Med Sci Sports Exerc"},{"key":"2407_CR17","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1093\/clinchem\/9.1.102","volume":"9","author":"JJ Coulombe","year":"1963","unstructured":"Coulombe JJ, Favreau L (1963) A new simple semimicro method for colorimetric determination of urea. Clin Chem 9:102\u2013108","journal-title":"Clin Chem"},{"key":"2407_CR21","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202401006","author":"L Das","year":"2024","unstructured":"Das L, Das M, Barkalita LM, Borah P (2024) Comprehensive analysis of antioxidant properties, GC-MS, and FTIR profiles of Myrica esculenta fruit extracts from Western East Khasi Hills of Meghalaya. Chem Biodivers. https:\/\/doi.org\/10.1002\/cbdv.202401006","journal-title":"Chem Biodivers"},{"key":"2407_CR22","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5048031","author":"K de P\u00e1dua L\u00facio","year":"2018","unstructured":"de P\u00e1dua L\u00facio K, Rabelo ACS, Ara\u00fajo CM, Brand\u00e3o GC, de Souza GHB, da Silva RG, de Souza DMS, Talvani A, Bezerra FS, Cruz Calsavara AJ, Costa DC (2018) Anti-inflammatory and antioxidant properties of black mulberry (Morus nigra L.) in a model of LPS-induced sepsis. Oxid Med Cell Longev. https:\/\/doi.org\/10.1155\/2018\/5048031","journal-title":"Oxid Med Cell Longev"},{"key":"2407_CR71","doi-asserted-by":"publisher","first-page":"6879183","DOI":"10.1155\/2018\/6879183","volume":"2018","author":"AJMCR de Pinheiro","year":"2018","unstructured":"Pinheiro AJMCR, Gon\u00e7alves JS, Dourado \u00c1WA, de Sousa EM, Brito N, Silva LK, Batista MCA, de S\u00e1 JC, Monteiro CRA, Fernandes ES, Monteiro-Neto V, Campbell LA, Zago PMW, Lima-Neto LG (2018) Punica granatum L leaf extract attenuates lung inflammation in mice with acute lung injury. J Immunol Res 2018:6879183. https:\/\/doi.org\/10.1155\/2018\/6879183.","journal-title":"J Immunol Res"},{"key":"2407_CR23","first-page":"145","volume":"6","author":"A Dhani","year":"2013","unstructured":"Dhani A (2013) Major wild edible fruits used by locals of Garhwal Himalaya. Int J Adv Life Sci 6:145\u2013149","journal-title":"Int J Adv Life Sci"},{"issue":"1","key":"2407_CR24","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/imr.12621","volume":"281","author":"CA Dinarello","year":"2018","unstructured":"Dinarello CA (2018) Overview of the IL-1 family in innate inflammation and acquired immunity. Immunol Rev 281(1):8\u201327. https:\/\/doi.org\/10.1111\/imr.12621","journal-title":"Immunol Rev"},{"key":"2407_CR25","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.cbi.2015.01.030","volume":"230","author":"R Domitrovi\u0107","year":"2015","unstructured":"Domitrovi\u0107 R, Rashed K, Cvijanovi\u0107 O, Vladimir-Kne\u017eevi\u0107 S, \u0160koda M, Vi\u0161ni\u0107 A (2015) Myricitrin exhibits antioxidant, anti-inflammatory and antifibrotic activity in carbon tetrachloride-intoxicated mice. Chem Biol Interact 230:21\u201329. https:\/\/doi.org\/10.1016\/j.cbi.2015.01.030","journal-title":"Chem Biol Interact"},{"key":"2407_CR26","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1016\/j.foodchem.2008.07.102","volume":"113","author":"Z Fang","year":"2009","unstructured":"Fang Z, Zhang Y, L\u00fc Y, Ma G, Chen J, Liu D, Ye X (2009) Phenolic compounds and antioxidant capacities of bayberry juices. Food Chem 113:884\u2013888. https:\/\/doi.org\/10.1016\/j.foodchem.2008.07.102","journal-title":"Food Chem"},{"key":"2407_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112104","volume":"143","author":"Y Fang","year":"2021","unstructured":"Fang Y, Yang L, He J (2021) Plantanone C attenuates LPS-stimulated inflammation by inhibiting NF-\u03baB\/iNOS\/COX-2\/MAPKs\/Akt pathways in RAW 264.7 macrophages. Biomed Pharmacother 143:112104. https:\/\/doi.org\/10.1016\/j.biopha.2021.112104","journal-title":"Biomed Pharmacother"},{"issue":"4","key":"2407_CR27","first-page":"1","volume":"11","author":"B Farquhar","year":"1997","unstructured":"Farquhar B, Kenney WL (1997) Anti-inflammatory drugs, kidney function, and exercise. Sports Sci Exch 11(4):1\u20135","journal-title":"Sports Sci Exch"},{"key":"2407_CR29","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00550","volume":"6","author":"TA Gottschalk","year":"2015","unstructured":"Gottschalk TA, Tsantikos E, Hibbs ML (2015) Pathogenic inflammation and its therapeutic targeting in systemic lupus erythematosus. Front Immunol 6:550. https:\/\/doi.org\/10.3389\/fimmu.2015.00550","journal-title":"Front Immunol"},{"key":"2407_CR30","doi-asserted-by":"publisher","first-page":"853","DOI":"10.2215\/CJN.00490206","volume":"1","author":"S Heemskerk","year":"2006","unstructured":"Heemskerk S, Pickkers P, Bouw MP, Draisma A, van der Hoeven JG, Peters WH, Smits P, Russel FG, Masereeuw R (2006) Upregulation of renal inducible nitric oxide synthase during human endotoxemia and sepsis is associated with proximal tubule injury. Clin J Am Soc Nephrol 1:853\u2013862. https:\/\/doi.org\/10.2215\/CJN.00490206","journal-title":"Clin J Am Soc Nephrol"},{"key":"2407_CR31","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/j.intimp.2016.06.027","volume":"38","author":"G Houshmand","year":"2016","unstructured":"Houshmand G, Mansouri MT, Naghizadeh B, Hemmati AA, Hashemitabar M (2016) Potentiation of indomethacin-induced anti-inflammatory response by pioglitazone in carrageenan-induced acute inflammation in rats: role of PPAR\u03b3 receptors. Int Immunopharmacol 38:434\u2013442. https:\/\/doi.org\/10.1016\/j.intimp.2016.06.027","journal-title":"Int Immunopharm"},{"key":"2407_CR32","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1016\/j.phymed.2018.08.001","volume":"55","author":"TY Hu","year":"2019","unstructured":"Hu TY, Ju JM, Mo LH, Ma L, Hu WH, You RR, Chen XQ, Chen YY, Liu ZQ, Qiu SQ, Fan JT, Cheng BH (2019) Anti-inflammatory action of xanthones from Swertia chirayita by regulating COX-2\/NF-\u03baB\/MAPKs\/Akt signaling pathways in RAW 264.7 macrophage cells. Phytomedicine 55:214\u2013221. https:\/\/doi.org\/10.1016\/j.phymed.2018.08.001","journal-title":"Phytomedicine"},{"issue":"9","key":"2407_CR33","doi-asserted-by":"publisher","first-page":"1377","DOI":"10.1111\/bph.14155","volume":"175","author":"S Huang","year":"2018","unstructured":"Huang S, Frangogiannis NG (2018) Anti-inflammatory therapies in myocardial infarction: failures, hopes and challenges. Br J Pharmacol 175(9):1377\u20131400. https:\/\/doi.org\/10.1111\/bph.14155","journal-title":"Br J Pharmacol"},{"issue":"6","key":"2407_CR34","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.3390\/nu11061412","volume":"11","author":"MS Islam","year":"2019","unstructured":"Islam MS, Miao L, Yu H, Han Z, Sun H (2019) Ethanol extract of Illicium henryi attenuates LPS-induced acute kidney injury in mice via regulating inflammation and oxidative stress. Nutrients 11(6):1412. https:\/\/doi.org\/10.3390\/nu11061412","journal-title":"Nutrients"},{"issue":"11","key":"2407_CR35","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.3109\/13880200902973787","volume":"47","author":"ML Jabit","year":"2009","unstructured":"Jabit ML, Wahyuni FS, Khalid R, Israf DA, Shaari K, Lajis NH, Stanslas J (2009) Cytotoxic and nitric oxide inhibitory activities of methanol extracts of Garcinia species. Pharm Biol 47(11):1019\u20131026. https:\/\/doi.org\/10.3109\/13880200902973787","journal-title":"Pharm Biol"},{"key":"2407_CR36","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/587143","author":"Z Jiang","year":"2018","unstructured":"Jiang Z, Meng Y, Bo L, Wang C, Bian J, Deng X (2018) Sophocarpine attenuates LPS-induced liver injury and improves survival of mice through suppressing oxidative stress, inflammation, and apoptosis. Mediators Inflamm. https:\/\/doi.org\/10.1155\/2018\/587143","journal-title":"Mediators Inflamm"},{"issue":"2","key":"2407_CR37","first-page":"12","volume":"17","author":"I Joung","year":"2019","unstructured":"Joung I, Oh JH, Lee MK, Chung JH (2019) Urea and its effects on the kidney: more than just a waste product. Electrolyte Blood Pres Sure 17(2):12\u201318","journal-title":"Electrolyte Blood Pres Sure"},{"key":"2407_CR47","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1007\/s10787-021-00832-9","volume":"29","author":"A Kalita","year":"2021","unstructured":"Kalita A, Das M, Baro MR, Das B (2021) Exploring the role of aquaporins (AQPs) in LPS induced systemic inflammation and the ameliorative effect of Garcinia in male Wistar rat. Inflammopharmacology 29:801\u2013823. https:\/\/doi.org\/10.1007\/s10787-021-00832-9","journal-title":"Inflammopharmacology"},{"key":"2407_CR48","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/s43088-022-00214-2","volume":"11","author":"A Kalita","year":"2022","unstructured":"Kalita A, Das M, Das B, Baro MR (2022) Molecular docking prediction and in vitro studies elucidate anti-inflammatory effect of Garcinia extract against inducible nitric oxide synthase and cyclooxygenase-2 targets Beni-Suef Univ J Basic Appl Sci 11:32. https:\/\/doi.org\/10.1186\/s43088-022-00214-2.","journal-title":"Beni-Suef Univ J Basic Appl Sci"},{"key":"2407_CR38","doi-asserted-by":"publisher","DOI":"10.2174\/0113816128404108251209112122","author":"A Karabhari","year":"2026","unstructured":"Karabhari A, Rathee S, Soni S, Patil UK (2026) Rheumatoid arthritis: a comprehensive review of etiology, pathophysiology, and innovative therapeutic advancements. Curr Pharm des. https:\/\/doi.org\/10.2174\/0113816128404108251209112122","journal-title":"Curr Pharm des"},{"key":"2407_CR39","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1046\/j.1365-2222.2001.01067.x","volume":"31","author":"SH Kim","year":"2001","unstructured":"Kim SH, Jeong H, Kim YK, Cho SH, Min KU, Kim YY (2001) IgE-mediated occupational asthma induced by herbal medicine, Banha (Pinellia ternata). Clin Exp Allergy 31:779\u2013781. https:\/\/doi.org\/10.1046\/j.1365-2222.2001.01067.x","journal-title":"Clin Exp Allergy"},{"key":"2407_CR40","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/728709","author":"JH Kim","year":"2014","unstructured":"Kim JH, Park GY, Bang SY, Park SY, Bae SK, Kim Y (2014a) Crocin suppresses LPS-stimulated expression of inducible nitric oxide synthase by upregulation of heme oxygenase-1 via calcium\/calmodulin-dependent protein kinase 4. Mediators Inflamm. https:\/\/doi.org\/10.1155\/2014\/728709","journal-title":"Mediators Inflamm"},{"key":"2407_CR41","doi-asserted-by":"publisher","DOI":"10.1186\/1476-9255-11-16","volume":"11","author":"YH Kim","year":"2014","unstructured":"Kim YH, Yoon DW, Kim JH (2014b) Effect of remote ischemic post-conditioning on systemic inflammatory response and survival rate in lipopolysaccharide-induced systemic inflammation model. J Inflamm 11:16. https:\/\/doi.org\/10.1186\/1476-9255-11-16","journal-title":"J Inflamm"},{"issue":"3","key":"2407_CR42","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21030392","volume":"21","author":"YS Kim","year":"2016","unstructured":"Kim YS, Hwang JW, Jang JH, Son S, Seo IB, Jeong JH, Kim EH, Moon SH, Jeon BT, Park PJ (2016) Trapa japonica pericarp extract reduces LPS-induced inflammation in macrophages and acute lung injury in mice. Molecules 21(3):392. https:\/\/doi.org\/10.3390\/molecules21030392","journal-title":"Molecules"},{"issue":"8","key":"2407_CR43","doi-asserted-by":"publisher","first-page":"1270","DOI":"10.3390\/ijms20122951","volume":"28","author":"S Kim","year":"2018","unstructured":"Kim S, Kook KE, Kim C, Hwang JK (2018) Inhibitory effects of Curcuma xanthorrhiza supercritical extract and Xanthorrhizol on LPS-induced inflammation in HGF-1 cells and RANKL-induced osteoclastogenesis in RAW2647 cells. J Microbiol Biotechnol 28(8):1270\u20131281. https:\/\/doi.org\/10.3390\/ijms20122951.","journal-title":"J Microbiol Biotechnol"},{"issue":"6","key":"2407_CR44","doi-asserted-by":"publisher","first-page":"822","DOI":"10.4014\/jmb.1911.11042","volume":"30","author":"JG Kim","year":"2020","unstructured":"Kim JG, Kim MJ, Lee JS, Sydara K, Lee S, Byun S, Jung SK (2020) Smilax guianensis Vitman extract prevents LPS-induced inflammation by inhibiting the NF-\u03baB pathway in RAW 264.7 cells. J Microbiol Biotechnol 30(6):822\u2013829. https:\/\/doi.org\/10.4014\/jmb.1911.11042","journal-title":"J Microbiol Biotechnol"},{"key":"2407_CR45","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.mam.2005.12.007","volume":"27","author":"M Kubista","year":"2006","unstructured":"Kubista M, Andrade JM, Bengtsson M, Forootan A, Jon\u00e1k J, Lind K, Sindelka R, Sj\u00f6back R, Sj\u00f6green B, Str\u00f6mbom L, St\u00e5hlberg A, Zoric N (2006) The real-time polymerase chain reaction. Mol Aspects Med 27:95\u2013125. https:\/\/doi.org\/10.1016\/j.mam.2005.12.007","journal-title":"Mol Aspects Med"},{"issue":"1","key":"2407_CR46","doi-asserted-by":"publisher","first-page":"59","DOI":"10.1080\/1057563031000122112","volume":"18","author":"JK Kumar","year":"2004","unstructured":"Kumar JK, Sinha AK (2004) Resurgence of natural colourants: a holistic view. Nat Prod Res 18(1):59\u201384. https:\/\/doi.org\/10.1080\/1057563031000122112","journal-title":"Nat Prod Res"},{"key":"2407_CR49","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.107264","volume":"91","author":"A Kumar","year":"2021","unstructured":"Kumar A, Sawhney G, Nagar RK, Chauhan N, Gupta N, Kaul A, Ahmed Z, Sangwan PL, Satheesh Kumar P, Yadav G (2021) Evaluation of the immunomodulatory and anti-inflammatory activity of bakuchiol using RAW 264.7 macrophage cell lines and in animal models stimulated by lipopolysaccharide (LPS). Int Immunopharmacol 91:107264. https:\/\/doi.org\/10.1016\/j.intimp.2020.107264","journal-title":"Int Immunopharmacol"},{"issue":"3","key":"2407_CR50","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1016\/j.jep.2009.05.007","volume":"124","author":"KH Lee","year":"2009","unstructured":"Lee KH, Yeh MH, Kao ST, Hung CM, Chen BC, Liu CJ, Yeh CC (2009) Xia-bai-san inhibits lipopolysaccharide-induced activation of intercellular adhesion molecule-1 and nuclear factor-kappa B in human lung cells. J Ethnopharmacol 124(3):530\u2013538. https:\/\/doi.org\/10.1016\/j.jep.2009.05.007","journal-title":"J Ethnopharmacol"},{"issue":"4","key":"2407_CR51","doi-asserted-by":"publisher","first-page":"978","DOI":"10.1002\/jcb.25383","volume":"117","author":"SH Lee","year":"2016","unstructured":"Lee SH, Kwak CH, Lee SK, Ha SH, Park J, Chung TW, Ha KT, Suh SJ, Chang YC, Chang HW, Lee YC, Kang BS, Magae J, Kim CH (2016) Anti-inflammatory effect of ascochlorin in LPS-stimulated RAW 264.7 macrophage cells is accompanied with the down-regulation of iNOS, COX-2 and proinflammatory cytokines through NF-\u03baB, ERK1\/2, and p38 signaling pathway. J Cell Biochem 117(4):978\u2013987. https:\/\/doi.org\/10.1002\/jcb.25383","journal-title":"J Cell Biochem"},{"issue":"9","key":"2407_CR52","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1093\/clinchem\/46.9.1353","volume":"46","author":"AS Levey","year":"2000","unstructured":"Levey AS, Coresh J, Greene T (2000) Creatinine and creatinine clearance in renal diagnostics. Clin Chem 46(9):1353\u20131362. https:\/\/doi.org\/10.1093\/clinchem\/46.9.1353","journal-title":"Clin Chem"},{"key":"2407_CR53","doi-asserted-by":"publisher","first-page":"1035","DOI":"10.1007\/s00011-019-01285-1","volume":"68","author":"B Li","year":"2019","unstructured":"Li B, Liu C, Tang K, Dong X, Xue L, Su G, Zhang W, Jin Y (2019) Aquaporin-1 attentues macrophage-mediated inflammatory response by inhibiting p38 mitogen-activated protein kinase activation in lipopolysaccharide-induced acute kidney injury. Inflamm Res 68:1035\u20131047. https:\/\/doi.org\/10.1007\/s00011-019-01285-1","journal-title":"Inflamm Res"},{"issue":"3","key":"2407_CR54","doi-asserted-by":"publisher","first-page":"465","DOI":"10.1124\/mol.52.3.465","volume":"52","author":"YL Lin","year":"1997","unstructured":"Lin YL, Lin JK (1997) (\u2212)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-\u03baB. Mol Pharmacol 52(3):465\u2013472. https:\/\/doi.org\/10.1124\/mol.52.3.465","journal-title":"Mol Pharmacol"},{"key":"2407_CR55","doi-asserted-by":"publisher","first-page":"106047","DOI":"10.1016\/j.intimp.2020.106482","volume":"78","author":"S Liu","year":"2020","unstructured":"Liu S, Yang T, Ming TW, Gaun TKW, Zhou T, Wang S, Ye B (2020) Isosteroid alkaloids with different chemical structures from Fritillariae cirrhosae bulbus alleviate LPS-induced inflammatory response in RAW 2647 cells by MAPK signaling pathway. Int Immunopharmacol 78:106047. https:\/\/doi.org\/10.1016\/j.intimp.2020.106482.","journal-title":"Int Immunopharmacol"},{"issue":"4","key":"2407_CR56","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1006\/meth.2001.1262","volume":"25","author":"KJ Livak","year":"2001","unstructured":"Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2\u2212\u0394\u0394CT method. Methods 25(4):402\u2013408. https:\/\/doi.org\/10.1006\/meth.2001.1262","journal-title":"Methods"},{"key":"2407_CR57","doi-asserted-by":"publisher","first-page":"604","DOI":"10.3389\/fimmu.2016.00604","volume":"7","author":"Y Luo","year":"2016","unstructured":"Luo Y, Zhen SG (2016) Hall of fame among pro-inflammatory cytokines: interleukin-6 gene and its transcriptional regulation mechanisms. Front Immunol 7:604. https:\/\/doi.org\/10.3389\/fimmu.2016.00604","journal-title":"Front Immunol"},{"key":"2407_CR58","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1476-9255-7-27","volume":"7","author":"J Lutz","year":"2010","unstructured":"Lutz J, Th\u00fcrmel K, Heemann U (2010) Anti-inflammatory treatment strategies for ischemia\/reperfusion injury in transplantation. J Inflamm 7:27. https:\/\/doi.org\/10.1186\/1476-9255-7-27","journal-title":"J Inflamm"},{"key":"2407_CR59","first-page":"1","volume":"5","author":"K Makdoh","year":"2014","unstructured":"Makdoh K, Lynser MB, Pala KHM (2014) Marketing of indigenous fruits: a source of income among Khasi women of Meghalaya. Northeast J Agric Sci 5:1\u20139","journal-title":"Northeast J Agric Sci"},{"issue":"10","key":"2407_CR60","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27103313","volume":"27","author":"S Mangmool","year":"2022","unstructured":"Mangmool S, Limpichai C, Han KK, Reutrakul V, Anantachoke N (2022) Anti-inflammatory effects of Mitrephora sirikitiae leaf extract and isolated lignans in RAW 264.7 cells. Molecules 27(10):3313. https:\/\/doi.org\/10.3390\/molecules27103313","journal-title":"Molecules"},{"issue":"1","key":"2407_CR61","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26010229","volume":"26","author":"T Meng","year":"2021","unstructured":"Meng T, Xiao D, Muhammed A, Deng J, Chen L, He J (2021) Anti-inflammatory action and mechanisms of resveratrol. Molecules 26(1):229. https:\/\/doi.org\/10.3390\/molecules26010229","journal-title":"Molecules"},{"issue":"12","key":"2407_CR62","doi-asserted-by":"publisher","first-page":"1707","DOI":"10.1016\/j.bcp.2006.08.028","volume":"72","author":"FC Meotti","year":"2006","unstructured":"Meotti FC, Missau FC, Ferreira J, Pizzolatti MG, Mizuzaki C, Nogueira CW, Santos ARS (2006) Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice. Biochem Pharmacol 72(12):1707\u20131713. https:\/\/doi.org\/10.1016\/j.bcp.2006.08.028","journal-title":"Biochem Pharmacol"},{"key":"2407_CR63","doi-asserted-by":"publisher","first-page":"3860","DOI":"10.1039\/c8fo00439k","volume":"9","author":"S Mohan","year":"2018","unstructured":"Mohan S, Syam S, Abdelwahab SI, Thangavel N (2018) An anti-inflammatory molecular mechanism of action of \u03b1-mangostin, the major xanthone from the pericarp of Garcinia mangostana: an in silico, in vitro and in vivo approach. Food Funct 9:3860\u20133871. https:\/\/doi.org\/10.1039\/c8fo00439k","journal-title":"Food Funct"},{"issue":"6","key":"2407_CR64","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1179\/096805101101533034","volume":"7","author":"MM Mu","year":"2001","unstructured":"Mu MM, Chakravortty D, Sugiyama T, Koide N, Takahashi K, Mori I, Yoshida T, Yokochi T (2001) The inhibitory action of quercetin on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells. J Endotoxin Res 7(6):431\u2013438. https:\/\/doi.org\/10.1179\/096805101101533034","journal-title":"J Endotoxin Res"},{"key":"2407_CR65","doi-asserted-by":"publisher","first-page":"3430684","DOI":"10.1155\/2018\/3430684","volume":"2018","author":"K Muniandy","year":"2018","unstructured":"Muniandy K, Gothai S, Badran KMH, Suresh Kumar S, Esa NM, Arulselvan P (2018) Suppression of proinflammatory cytokines and mediators in LPS-induced RAW 2647 macrophages by stem extract of Alternanthera sessilis via the inhibition of the NF-\u03baB pathway. J Immunol Res 2018:3430684. https:\/\/doi.org\/10.1155\/2018\/3430684.","journal-title":"J Immunol Res"},{"issue":"1","key":"2407_CR103","first-page":"204","volume":"5","author":"ID Musfiroh","year":"2013","unstructured":"Musfiroh ID, Muhtadi A, Kartasasmita RE, Tjahjono DH (2013) In silico study of asiatic acid interaction with inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). Int J Pharm Pharm Sci 5(Suppl 1):204\u2013207","journal-title":"Int J Pharm Pharm Sci"},{"issue":"6917","key":"2407_CR66","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1038\/nature01320","volume":"420","author":"C Nathan","year":"2002","unstructured":"Nathan C (2002) Points of control in inflammation. Nature 420(6917):846\u2013852. https:\/\/doi.org\/10.1038\/nature01320","journal-title":"Nature"},{"issue":"15","key":"2407_CR67","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1517\/14740338.2016.1140743","volume":"2016","author":"M Oray","year":"2016","unstructured":"Oray M, Abu Samra K, Ebrahimiadib N, Meese H, Foster CS (2016) Long-term side effects of glucocorticoids. Expert Opin Drug Saf 2016(15):457\u2013465. https:\/\/doi.org\/10.1517\/14740338.2016.1140743","journal-title":"Expert Opin Drug Saf"},{"key":"2407_CR68","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1146\/annurev-immunol-031210-101312","volume":"29","author":"W Ouyang","year":"2011","unstructured":"Ouyang W, Rutz S, Crellin NK, Valdez PA, Hymowitz SG (2011) Regulation and functions of the IL-10 family of cytokines in inflammation and disease. Annu Rev Immunol 29:71\u2013109. https:\/\/doi.org\/10.1146\/annurev-immunol-031210-101312","journal-title":"Annu Rev Immunol"},{"key":"2407_CR69","first-page":"57","volume":"8","author":"NA Pala","year":"2010","unstructured":"Pala NA, Negi AK, Todaria NP (2010) Traditional uses of medicinal plants of Pauri Garhwal, Uttarakhand. Nat Sci 8:57\u201361","journal-title":"Nat Sci"},{"key":"2407_CR70","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1038\/s41577-020-0391-5","volume":"21","author":"SR Paludan","year":"2021","unstructured":"Paludan SR, Pradeu T, Masters SL et al (2021) Constitutive immune mechanisms: mediators of host defence and immune regulation. Nat Rev Immunol 21:137\u2013150. https:\/\/doi.org\/10.1038\/s41577-020-0391-5","journal-title":"Nat Rev Immunol"},{"issue":"4","key":"2407_CR72","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1194\/jlr.R600021-JLR200","volume":"48","author":"C Popa","year":"2007","unstructured":"Popa C, Netea MG, van Riel PL, van der Meer JW, Stalenhoef AF (2007) The role of TNF-alpha in chronic inflammatory conditions, intermediary metabolism, and cardiovascular risk. J Lipid Res 48(4):751\u2013762. https:\/\/doi.org\/10.1194\/jlr.R600021-JLR200","journal-title":"J Lipid Res"},{"issue":"10","key":"2407_CR73","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1007\/s00011-019-01267-3","volume":"68","author":"M Pudla","year":"2019","unstructured":"Pudla M, Srisaowakarn C, Utaisincharoen P (2019) NLRP12 negatively modulates inducible nitric oxide synthase (iNOS) expression and tumor necrosis factor-\u03b1 production in Porphyromonas gingivalis LPS-treated mouse macrophage cell line (RAW264.7). Inflamm Res 68(10):841\u2013844. https:\/\/doi.org\/10.1007\/s00011-019-01267-3","journal-title":"Inflamm Res"},{"key":"2407_CR75","first-page":"19","volume":"13","author":"N Rai","year":"2005","unstructured":"Rai N, Asati BS, Patel RK, Patel KK, Yadav DS (2005) Underutilized horticultural crops in the northeastern region. ENVIS Bulletin: Himalayan Ecology 13:19\u201329","journal-title":"ENVIS Bulletin: Himalayan Ecology"},{"issue":"1","key":"2407_CR76","doi-asserted-by":"publisher","first-page":"31","DOI":"10.4103\/2229-516X.149232","volume":"5","author":"L Ray","year":"2015","unstructured":"Ray L, Nanda SK, Chatterjee A, Sarangi R, Ganguly S (2015) A comparative study of serum aminotransferases in chronic kidney disease with and without end-stage renal disease: need for new reference ranges. Int J Appl Basic Med Res 5(1):31\u201335. https:\/\/doi.org\/10.4103\/2229-516X.149232","journal-title":"Int J Appl Basic Med Res"},{"issue":"5","key":"2407_CR77","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1002\/ptr.1180","volume":"17","author":"JH Ryu","year":"2003","unstructured":"Ryu JH, Ahn H, Kim JY, Kim YK (2003) Inhibitory activity of plant extracts on nitric oxide synthesis in LPS-activated macrophages. Phytother Res 17(5):485\u2013489. https:\/\/doi.org\/10.1002\/ptr.1180","journal-title":"Phytother Res"},{"key":"2407_CR78","doi-asserted-by":"publisher","DOI":"10.1101\/pdb.prot4455","author":"J Sambrook","year":"2006","unstructured":"Sambrook J, Russell DW (2006) Purification of nucleic acids by extraction with phenol: chloroform. Cold Spring Harb Protoc. https:\/\/doi.org\/10.1101\/pdb.prot4455","journal-title":"Cold Spring Harb Protoc"},{"key":"2407_CR79","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2022.104895","volume":"107","author":"MA Santos","year":"2023","unstructured":"Santos MA, Franco FN, Caldeira CA, de Ara\u00fajo GR, Vieira A, Chaves MM (2023) Resveratrol has its antioxidant and anti-inflammatory protective mechanisms decreased in aging. Arch Gerontol Geriatr 107:104895. https:\/\/doi.org\/10.1016\/j.archger.2022.104895","journal-title":"Arch Gerontol Geriatr"},{"key":"2407_CR81","doi-asserted-by":"publisher","first-page":"294","DOI":"10.3389\/fphar.2016.00294","volume":"7","author":"R Sarma","year":"2016","unstructured":"Sarma R, Kumari S, Elancheran R, Deori M, Devi R (2016) Polyphenol rich extract of Garcinia pedunculata fruit attenuates the hyperlipidemia induced by high fat diet. Front Pharmacol 7:294. https:\/\/doi.org\/10.3389\/fphar.2016.00294","journal-title":"Front Pharmacol"},{"key":"2407_CR102","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.106576","volume":"86","author":"SY Shim","year":"2020","unstructured":"Shim SY, Lee M (2020) Anti-inflammatory activity of phenylpropyl triterpenoids from Osmanthus fragrans var. aurantiacus leaves. Int Immunopharmacol 86:106576. https:\/\/doi.org\/10.1016\/j.intimp.2020.106576","journal-title":"Int Immunopharmacol"},{"key":"2407_CR82","doi-asserted-by":"publisher","first-page":"52","DOI":"10.3390\/ECB2023-14079","volume":"21","author":"AK Shrivastava","year":"2023","unstructured":"Shrivastava AK, Chaudhary D, Shrestha L, Awadalla ME, Al-Shouli ST, Palikhey A, Eltayb WA, Gupta A, Gupta PP, Parab M, Trivedi A, Srivastava A, Abdalla M (2023) GC-MS based metabolite profiling and anti-inflammatory activity of aqueous extract of Myrica esculenta through in vitro and in silico approach. Med Sci Forum 21:52. https:\/\/doi.org\/10.3390\/ECB2023-14079","journal-title":"Med Sci Forum"},{"issue":"5B","key":"2407_CR83","doi-asserted-by":"publisher","first-page":"37S","DOI":"10.1016\/S0002-9343(99)00115-1","volume":"106","author":"LS Simon","year":"1999","unstructured":"Simon LS (1999) Role and regulation of cyclooxygenase-2 during inflammation. Am J Med 106(5B):37S-42S. https:\/\/doi.org\/10.1016\/S0002-9343(99)00115-1","journal-title":"Am J Med"},{"issue":"4","key":"2407_CR84","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1016\/j.jaim.2016.08.004","volume":"7","author":"B Srivastava","year":"2016","unstructured":"Srivastava B, Sharma VC, Pant P, Pandey N, Jadhav A (2016) Evaluation for substitution of stem bark with small branches of Myrica esculenta for medicinal use: a comparative phytochemical study. J Ayurveda Integr Med 7(4):218\u2013223. https:\/\/doi.org\/10.1016\/j.jaim.2016.08.004","journal-title":"J Ayurveda Integr Med"},{"issue":"10","key":"2407_CR85","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a016295","volume":"6","author":"T Tanaka","year":"2014","unstructured":"Tanaka T, Narazaki M, Kishimoto T (2014) IL-6 in inflammation, immunity, and disease. Cold Spring Harb Perspect Biol 6(10):a016295. https:\/\/doi.org\/10.1101\/cshperspect.a016295","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"2407_CR86","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1016\/j.foodres.2015.07.044","volume":"76","author":"O Taofiq","year":"2015","unstructured":"Taofiq O, Calhelha RC, Heleno S, Barros L, Martins A, Santos-Buelga C, Queiroz MJRP, Ferreira ICFR (2015) The contribution of phenolic acids to the anti-inflammatory activity of mushrooms: screening in phenolic extracts, individual parent molecules and synthesized glucuronated and methylated derivatives. Food Res Int 76:821\u2013827. https:\/\/doi.org\/10.1016\/j.foodres.2015.07.044","journal-title":"Food Res Int"},{"issue":"2","key":"2407_CR87","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/s0306-3623(96)00410-7","volume":"29","author":"C Thiemermann","year":"1997","unstructured":"Thiemermann C (1997) Nitric oxide and septic shock. Gen Pharmacol 29(2):159\u2013166. https:\/\/doi.org\/10.1016\/s0306-3623(96)00410-7","journal-title":"Gen Pharmacol"},{"issue":"6","key":"2407_CR104","doi-asserted-by":"publisher","first-page":"623","DOI":"10.6026\/97320630017623","volume":"17","author":"D Tripathi","year":"2021","unstructured":"Tripathi D, Koora S, Satyanarayana K, Basha SS, Jayaraman S (2021) Molecular docking analysis of COX-2 with compounds from Piper longum. Bioinformation 17(6):623\u2013627. https:\/\/doi.org\/10.6026\/97320630017623","journal-title":"Bioinformation"},{"issue":"1","key":"2407_CR88","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.jaim.2017.09.007","volume":"11","author":"A Vysakh","year":"2020","unstructured":"Vysakh A, Jayesh K, Helen LR, Jyothis M, Latha MS (2020) Acute oral toxicity and anti-inflammatory evaluation of methanolic extract of Rotula aquatica roots in Wistar rats. J Ayurveda Integr Med 11(1):45\u201352. https:\/\/doi.org\/10.1016\/j.jaim.2017.09.007","journal-title":"J Ayurveda Integr Med"},{"key":"2407_CR89","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2020.113490","volume":"267","author":"LY Wang","year":"2021","unstructured":"Wang LY, Gu JP, Zong MY, Zhang QR, Li HX, Li DN, Mou XF, Liu P, Liu YN, Qiu F, Zhao F (2021) Anti-inflammatory action of physalin A by blocking the activation of NF-\u03baB signaling pathway. J Ethnopharmacol 267:113490. https:\/\/doi.org\/10.1016\/j.jep.2020.113490","journal-title":"J Ethnopharmacol"},{"issue":"10","key":"2407_CR90","doi-asserted-by":"publisher","DOI":"10.1111\/1753-0407.70014","volume":"16","author":"R Weinberg Sibony","year":"2024","unstructured":"Weinberg Sibony R, Segev O, Dor S, Raz I (2024) Overview of oxidative stress and inflammation in diabetes. J Diabetes 16(10):e70014. https:\/\/doi.org\/10.1111\/1753-0407.70014","journal-title":"J Diabetes"},{"issue":"3","key":"2407_CR91","doi-asserted-by":"publisher","first-page":"147","DOI":"10.20307\/nps.2016.22.3.147","volume":"22","author":"W Widowati","year":"2016","unstructured":"Widowati W, Darsono L, Suherman J, Fauziah N, Maesaroh M, Erawi jantari PP (2016) Anti-inflammatory effect of mangosteen (Garcinia mangostana L.) peel extract and its compounds in LPS induced RAW264.7 cells. Nat Prod Sci 22(3):147\u2013153. https:\/\/doi.org\/10.20307\/nps.2016.22.3.147","journal-title":"Nat Prod Sci"},{"key":"2407_CR92","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2020.106511","volume":"84","author":"Z Yan","year":"2020","unstructured":"Yan Z, Lin Z, Wu Y, Zhan J, Qi W, Lin J, Shen J, Xue X, Pan X (2020) The protective effect of myricitrin in osteoarthritis: an in vitro and in vivo study. Int Immunopharmacol 84:106511. https:\/\/doi.org\/10.1016\/j.intimp.2020.106511","journal-title":"Int Immunopharmacol"},{"key":"2407_CR93","first-page":"66","volume-title":"Pathology","author":"GH Yang","year":"2001","unstructured":"Yang GH (2001) Pathology, vol 5. People Health Publishing Company, Beijing, pp 66\u201368"},{"issue":"19","key":"2407_CR97","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v31.i19.106406","volume":"31","author":"QH Yang","year":"2025","unstructured":"Yang QH, Zhang CN (2025) Comparative study on the pathogenesis of Crohn\u2019s disease and ulcerative colitis. World J Gastroenterol 31(19):106406. https:\/\/doi.org\/10.3748\/wjg.v31.i19.106406","journal-title":"World J Gastroenterol"},{"key":"2407_CR94","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1007\/978-1-60327-530-9_8","volume":"512","author":"GY Yang","year":"2009","unstructured":"Yang GY, Taboada S, Liao J (2009) Induced nitric oxide synthase as a major player in the oncogenic transformation of inflamed tissue. Methods Mol Biol 512:119\u2013156. https:\/\/doi.org\/10.1007\/978-1-60327-530-9_8","journal-title":"Methods Mol Biol"},{"key":"2407_CR96","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-021-01452-9","author":"L Yang","year":"2021","unstructured":"Yang L, Liu R, Ouyang S, Zou M, Duan Y, Li L, Guan T, Zhang T, He J (2021) Compounds DRG and DAG, two phenol glycosides, inhibit TNF \u03b1-stimulated inflammatory response through blocking NF-\u03baB\/AKT\/JNK signaling pathways in MH7A cells. Inflammation. https:\/\/doi.org\/10.1007\/s10753-021-01452-9","journal-title":"Inflammation"},{"issue":"12","key":"2407_CR95","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20122951","volume":"20","author":"F Yao","year":"2019","unstructured":"Yao F, Xue Q, Li K, Cao X, Sun L, Liu Y (2019) Phenolic compounds and ginsenosides in ginseng shoots and their antioxidant and anti-inflammatory capacities in LPS-induced RAW264.7 mouse macrophages. Int J Mol Sci 20(12):2951. https:\/\/doi.org\/10.3390\/ijms20122951","journal-title":"Int J Mol Sci"},{"issue":"7","key":"2407_CR98","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1007\/s00011-013-0633-0","volume":"62","author":"H Zelov\u00e1","year":"2013","unstructured":"Zelov\u00e1 H, Ho\u0161ek J (2013) TNF-\u03b1 signalling and inflammation: interactions between old acquaintances. Inflamm Res 62(7):641\u2013651. https:\/\/doi.org\/10.1007\/s00011-013-0633-0","journal-title":"Inflamm Res"},{"key":"2407_CR99","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00658-5","volume":"6","author":"H Zhao","year":"2021","unstructured":"Zhao H, Wu L, Yan G, Chen Y, Zhou M, Wu Y, Li Y (2021) Inflammation and tumor progression: signaling pathways and targeted intervention. Signal Transduct Target Ther 6:263. https:\/\/doi.org\/10.1038\/s41392-021-00658-5","journal-title":"Signal Transduct Target Ther"},{"key":"2407_CR100","doi-asserted-by":"publisher","first-page":"113497","DOI":"10.1016\/j.jep.2020.113497","volume":"267","author":"YR Zheng","year":"2021","unstructured":"Zheng YR, Tian CY, Fan CL, Xu NS, Xiao JJ, Zhao XY, Lu ZB, Cao HH, Liu JS, Yu LZ (2021) Sheng-Mai Yin exerts anti-inflammatory effects on RAW 2647 cells and zebrafish. J Ethnopharmacol 267:113497. https:\/\/doi.org\/10.1016\/j.jep.2020.113497.","journal-title":"J Ethnopharmacol"},{"issue":"2","key":"2407_CR101","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1016\/j.foodchem.2012.02.172","volume":"134","author":"Y Zhong","year":"2012","unstructured":"Zhong Y, Chiou Y-S, Pan M-H, Shahidi F (2012) Anti-inflammatory activity of lipophilic epigallocatechin gallate (EGCG) derivatives in LPS-stimulated murine macrophages. Food Chem 134(2):742\u2013748. https:\/\/doi.org\/10.1016\/j.foodchem.2012.02.172","journal-title":"Food Chem"}],"container-title":["Inflammopharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-026-02407-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10787-026-02407-y","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10787-026-02407-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T10:22:21Z","timestamp":1790331741000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10787-026-02407-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,25]]},"references-count":101,"alternative-id":["2407"],"URL":"https:\/\/doi.org\/10.1007\/s10787-026-02407-y","relation":{},"ISSN":["0925-4692","1568-5608"],"issn-type":[{"value":"0925-4692","type":"print"},{"value":"1568-5608","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,25]]},"assertion":[{"value":"1 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Authors declares no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Institutional Animal Ethical Committee (IAEC\/2024\/Ethical-Per\/PhD-IAEC\/2024\u20132).","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}