{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,9]],"date-time":"2026-02-09T13:35:47Z","timestamp":1770644147784,"version":"3.49.0"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T00:00:00Z","timestamp":1461196800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1007\/s10792-016-0234-3","type":"journal-article","created":{"date-parts":[[2016,4,21]],"date-time":"2016-04-21T06:59:15Z","timestamp":1461221955000},"page":"103-109","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Outcomes of corneal collagen crosslinking using a customized epithelial debridement technique in keratoconic eyes with thin corneas"],"prefix":"10.1007","volume":"37","author":[{"given":"Nurullah","family":"Cagil","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozge","family":"Sarac","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gamze Dereli","family":"Can","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine","family":"Akcay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet Erol","family":"Can","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,4,21]]},"reference":[{"key":"234_CR1","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","volume":"42","author":"YS Rabinowitz","year":"1998","unstructured":"Rabinowitz YS (1998) Keratoconus. Surv Ophthalmol 42:297\u2013319","journal-title":"Surv Ophthalmol"},{"key":"234_CR2","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.clae.2010.04.006","volume":"33","author":"M Romero-Jimenez","year":"2010","unstructured":"Romero-Jimenez M, Santodomingo-Rubido J, Wolffsohn JS (2010) Keratoconus: a review. Contact Lens Anterior Eye 33:157\u2013166","journal-title":"Contact Lens Anterior Eye"},{"key":"234_CR3","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1097\/00003226-200005000-00014","volume":"19","author":"SC Brierly","year":"2000","unstructured":"Brierly SC, Izquierdo L, Mannis MJ (2000) Penetrating keratoplasty for keratoconus. Cornea 19:329\u2013332","journal-title":"Cornea"},{"key":"234_CR4","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","volume":"135","author":"G Wollensak","year":"2003","unstructured":"Wollensak G, Spoerl E, Seiler T (2003) Riboflavin\/ultraviolet-A-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 135:620\u2013627","journal-title":"Am J Ophthalmol"},{"key":"234_CR5","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.jcrs.2010.07.030","volume":"37","author":"PS Hersh","year":"2011","unstructured":"Hersh PS, Greenstein SA, Fry KL (2011) Corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. J Cataract Refract Surg 37:149\u2013160","journal-title":"J Cataract Refract Surg"},{"key":"234_CR6","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.jcrs.2011.01.029","volume":"37","author":"SA Greenstein","year":"2011","unstructured":"Greenstein SA, Fry KL, Hersh PS (2011) Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. J Cataract Refract Surg 37:1282\u20131290","journal-title":"J Cataract Refract Surg"},{"key":"234_CR7","doi-asserted-by":"crossref","first-page":"793","DOI":"10.5301\/ejo.5000313","volume":"23","author":"I Toprak","year":"2013","unstructured":"Toprak I, Yildirim C (2013) Scheimpflug parameters after corneal collagen crosslinking for keratoconus. Eur J Ophthalmol 23:793\u2013798","journal-title":"Eur J Ophthalmol"},{"key":"234_CR8","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/j.jcrs.2009.03.025","volume":"35","author":"GD Kymionis","year":"2009","unstructured":"Kymionis GD, Karavitaki AE, Kounis GA, Portaliou DM, Yoo SH, Pallikaris IG (2009) Management of pellucid marginal corneal degeneration with simultaneous customized photorefractive keratectomy and collagen crosslinking. J Cataract Refract Surg 35:1298\u20131301","journal-title":"J Cataract Refract Surg"},{"key":"234_CR9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2415-9-10","volume":"9","author":"GD Kymionis","year":"2009","unstructured":"Kymionis GD, Diakonis VF, Coskunseven E, Jankov M, Yoo SH, Pallikaris IG (2009) Customized pachymetric guided epithelial debridement for corneal collagen cross linking. BMC Ophthalmol 9:1\u20134","journal-title":"BMC Ophthalmol"},{"key":"234_CR10","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3928\/1081597X-20101201-01","volume":"27","author":"V Kaya","year":"2011","unstructured":"Kaya V, Utine CA, Yilmaz OF (2011) Efficacy of corneal collagen cross-linking using a custom epithelial debridement technique in thin corneas: a confocal microscopy study. J Refract Surg 27:444\u2013450","journal-title":"J Refract Surg"},{"key":"234_CR11","doi-asserted-by":"crossref","first-page":"1809","DOI":"10.1016\/j.jcrs.2011.04.033","volume":"37","author":"G Savini","year":"2011","unstructured":"Savini G, Barboni P, Carbonelli M, Hoffer KJ (2011) Repeatability of automatic measurements by a new Scheimpflug camera combined with Placido topography. J Cataract Refract Surg 37:1809\u20131816","journal-title":"J Cataract Refract Surg"},{"key":"234_CR12","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1097\/ICO.0b013e318211401f","volume":"30","author":"M Barnett","year":"2011","unstructured":"Barnett M, Mannis MJ (2011) Contact lenses in the management of keratoconus. Cornea 30:1510\u20131516","journal-title":"Cornea"},{"key":"234_CR13","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1097\/ICU.0b013e3283622a2c","volume":"4","author":"J Park","year":"2013","unstructured":"Park J, Gritz DC (2013) Evolution in the use of intrastromal corneal ring segments for corneal ectasia. Curr Opin Ophthalmol 4:296\u2013301","journal-title":"Curr Opin Ophthalmol"},{"key":"234_CR14","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/cxo.12047","volume":"96","author":"D Cassidy","year":"2013","unstructured":"Cassidy D, Beltz J, Jhanji V, Loughnan MS (2013) Recent advances in corneal transplantation for keratoconus. Clin Exp Optom 96:165\u2013172","journal-title":"Clin Exp Optom"},{"key":"234_CR15","first-page":"121","volume":"38","author":"A Daxer","year":"1997","unstructured":"Daxer A, Fratzl P (1997) Collagen fibril orientation in the human corneal stroma and its implication in keratoconus. Invest Ophthalmol Vis Sci 38:121\u2013129","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"234_CR16","first-page":"2244","volume":"32","author":"Y Komai","year":"1991","unstructured":"Komai Y, Ushiki T (1991) The three-dimensional organization of collagen fibrils in the human cornea and sclera. Invest Ophthalmol Vis Sci 32:2244\u20132258","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"234_CR17","first-page":"1117","volume":"9","author":"L Zhou","year":"1998","unstructured":"Zhou L, Sawaguchi S, Twining SS, Sugar J, Feder RS, Yue BY (1998) Expression of degradative enzymes and protease inhibitors in corneas with keratoconus. Invest Ophthalmol Vis Sci 9:1117\u20131124","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"234_CR18","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1167\/iovs.04-0549","volume":"46","author":"MC Kenney","year":"2005","unstructured":"Kenney MC, Chwa M, Atilano SR, Tran A, Carballo M, Saghizadeh M, Vasiliou V, Adachi W, Brown DJ (2005) Increased levels of catalase and cathepsin V\/L2 but decreased TIMP-1 in keratoconus corneas: evidence that oxidative stress plays a role in this disorder. Invest Ophthalmol Vis Sci 46:823\u2013832","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"234_CR19","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/j.jcrs.2013.01.026","volume":"39","author":"IM Beshtawi","year":"2013","unstructured":"Beshtawi IM, O\u2019Donnell C, Radhakrishnan H (2013) Biomechanical properties of corneal tissue after ultraviolet-A-riboflavin crosslinking. J Cataract Refract Surg 39:451\u2013462","journal-title":"J Cataract Refract Surg"},{"key":"234_CR20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/0974-9233.61213","volume":"17","author":"MR Jankov Ii","year":"2010","unstructured":"Jankov Ii MR, Jovanovic V, Nikolic L, Lake JC, Kymionis G, Coskunseven E (2010) Corneal collagen cross-linking. Middle East Afr J Ophthalmol 17:21\u201327","journal-title":"Middle East Afr J Ophthalmol"},{"key":"234_CR21","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1097\/01.icu.0000233954.86723.25","volume":"17","author":"G Wollensak","year":"2006","unstructured":"Wollensak G (2006) Crosslinking treatment of progressive keratoconus: new hope. Curr Opin Ophthalmol 17:356\u2013360","journal-title":"Curr Opin Ophthalmol"},{"key":"234_CR22","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1755-3768.2008.01474.x","volume":"88","author":"G Wollensak","year":"2010","unstructured":"Wollensak G (2010) Histological changes in human cornea after cross-linking with riboflavin and ultraviolet A. Acta Ophthalmol 88:17\u201318","journal-title":"Acta Ophthalmol"},{"key":"234_CR23","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1038\/sj.eye.6700751","volume":"18","author":"G Wollensak","year":"2004","unstructured":"Wollensak G, Spoerl E, Reber F, Seiler T (2004) Keratocyte cytotoxicity of riboflavin\/UVA treatment in vitro. Eye 18:718\u2013722","journal-title":"Eye"},{"key":"234_CR24","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/S0886-3350(03)00343-2","volume":"29","author":"G Wollensak","year":"2003","unstructured":"Wollensak G, Spoerl E, Wilsch M, Seiler T (2003) Endothelial cell damage after riboflavin-ultraviolet: a treatment in the rabbit. J Cataract Refract Surg 29:1786\u20131790","journal-title":"J Cataract Refract Surg"},{"key":"234_CR25","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.jcrs.2008.10.060","volume":"35","author":"F Hafezi","year":"2009","unstructured":"Hafezi F, Mrochen M, Iseli HP, Seiler T (2009) Collagen crosslinking with ultraviolet-A and hypoosmolar riboflavin solution in thin corneas. J Cataract Refract Surg 35:621\u2013624","journal-title":"J Cataract Refract Surg"},{"key":"234_CR26","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1097\/ICO.0b013e31820143d1","volume":"30","author":"F Hafezi","year":"2011","unstructured":"Hafezi F (2011) Limitation of collagen cross-Linking with hypoosmolar riboflavin solution: failure in an extremely thin cornea. Cornea 30:917\u2013919","journal-title":"Cornea"},{"key":"234_CR27","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/j.jcrs.2013.03.026","volume":"39","author":"A Caporossi","year":"2013","unstructured":"Caporossi A, Mazzotta C, Paradiso AL, Baiocchi S, Marigliani D, Caporossi T (2013) Transepithelial corneal collagen crosslinking for progressive keratoconus: 24-month clinical results. J Cataract Refract Surg 39:1157\u20131163","journal-title":"J Cataract Refract Surg"},{"key":"234_CR28","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.jcrs.2013.03.017","volume":"39","author":"AG Salman","year":"2013","unstructured":"Salman AG (2013) Transepithelial corneal collagen crosslinking for progressive keratoconus in a pediatric age group. J Cataract Refract Surg 39:1164\u20131170","journal-title":"J Cataract Refract Surg"},{"key":"234_CR29","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.2147\/OPTH.S37335","volume":"6","author":"L Spadea","year":"2012","unstructured":"Spadea L, Mencucci R (2012) Transepithelial corneal collagen cross-linking in ultrathin keratoconic corneas. Clin Ophthalmol 6:1785\u20131792","journal-title":"Clin Ophthalmol"},{"key":"234_CR30","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.2147\/OPTH.S66372","volume":"8","author":"C Mazzotta","year":"2014","unstructured":"Mazzotta C, Ramovecchi V (2014) Customized epithelial debridement for thin ectatic corneas undergoing corneal cross-linking: epithelial island cross-linking technique. Clin Ophthalmol 8:1337\u20131343","journal-title":"Clin Ophthalmol"},{"key":"234_CR31","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ajo.2011.05.036","volume":"153","author":"GD Kymionis","year":"2012","unstructured":"Kymionis GD, Portaliou DM, Diakonis VF, Kounis GA, Panagopoulou SI, Grentzelos MA (2012) Corneal collagen cross-linking with riboflavin and ultraviolet-A irradiation in patients with thin corneas. Am J Ophthalmol 153:24\u201328","journal-title":"Am J Ophthalmol"},{"key":"234_CR32","doi-asserted-by":"crossref","first-page":"7601","DOI":"10.1167\/iovs.14-15662","volume":"55","author":"N Bouheraoua","year":"2014","unstructured":"Bouheraoua N, Jouve L, El Sanharawi M, Sandali O, Temstet C, Loriaut P, Basli E, Borderie V, Laroche L (2014) Optical coherence tomography and confocal microscopy following three different protocols of corneal collagen-crosslinking in keratoconus. Invest Ophthalmol Vis Sci 55:7601\u20137609","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"234_CR33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s40662-015-0030-6","volume":"2","author":"L Mastropasqua","year":"2015","unstructured":"Mastropasqua L (2015) Collagen cross-linking: when and how? A review of the state of the art of the technique and new perspectives. Eye Vis (Lond) 2:19","journal-title":"Eye Vis (Lond)"},{"key":"234_CR34","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.jtos.2015.04.007","volume":"13","author":"C Mazzotta","year":"2015","unstructured":"Mazzotta C, Hafezi F, Kymionis G, Caragiuli S, Jacob S, Traversi C, Barabino S, Randleman JB (2015) In vivo confocal microscopy after corneal collagen crosslinking. Ocul Surf 13:298\u2013314","journal-title":"Ocul Surf"},{"key":"234_CR35","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1097\/ICO.0b013e3181cc7961","volume":"31","author":"FC Abib","year":"2012","unstructured":"Abib FC, Holzchuh R, Schaefer A, Schaefer T, Godois R (2012) The endothelial sample size analysis in corneal specular microscopy clinical examinations. Cornea 31:546\u2013550","journal-title":"Cornea"},{"key":"234_CR36","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/ICO.0000000000000385","volume":"34","author":"N Luft","year":"2015","unstructured":"Luft N, Hirnschall N, Schuschitz S, Draschl P, Findl O (2015) Comparison of 4 specular microscopes in healthy eyes and eyes with cornea guttata or corneal grafts. Cornea 34:381\u2013386","journal-title":"Cornea"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-016-0234-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s10792-016-0234-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-016-0234-3","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-016-0234-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T22:00:21Z","timestamp":1718488821000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s10792-016-0234-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,21]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["234"],"URL":"https:\/\/doi.org\/10.1007\/s10792-016-0234-3","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"value":"0165-5701","type":"print"},{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,21]]}}}