{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,26]],"date-time":"2026-04-26T04:53:08Z","timestamp":1777179188606,"version":"3.51.4"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T00:00:00Z","timestamp":1506124800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2017,9,23]],"date-time":"2017-09-23T00:00:00Z","timestamp":1506124800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1007\/s10792-017-0713-1","type":"journal-article","created":{"date-parts":[[2017,9,22]],"date-time":"2017-09-22T22:49:23Z","timestamp":1506120563000},"page":"2127-2132","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Electron microscopic evaluation of anterior lens epithelium in patients with idiopathic congenital cataract"],"prefix":"10.1007","volume":"38","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7461-6129","authenticated-orcid":false,"given":"Kemal","family":"Tekin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasemin Ozdamar","family":"Erol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merve","family":"Inanc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa Fevzi","family":"Sargon","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cigdem Ulku","family":"Can","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sibel","family":"Polat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pelin","family":"Yilmazbas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,9,23]]},"reference":[{"key":"713_CR1","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1007\/s00431-012-1700-1","volume":"171","author":"WH Chan","year":"2012","unstructured":"Chan WH, Biswas S, Ashworth JL, Lyold IC (2012) Congenital and infantile cataract: aetiology and management. Eur J Pediatr 171:625\u2013630","journal-title":"Eur J Pediatr"},{"key":"713_CR2","first-page":"19","volume":"79","author":"RB Prado","year":"2016","unstructured":"Prado RB, Silva VF, Schellini SA, Rodrigues AC (2016) Congenital and development cataract: axial length and keratometry study in Brazilian children. Arq Bras Ophthalmol 79:19\u201323","journal-title":"Arq Bras Ophthalmol"},{"key":"713_CR3","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1016\/j.jcrs.2005.01.012","volume":"31","author":"C Zetterstr\u00f6m","year":"2005","unstructured":"Zetterstr\u00f6m C, Lundvall A, Kugelberg M (2005) Cataracts\u00a0in\u00a0children. J Cataract Refract Surg 31:824\u2013840","journal-title":"J Cataract Refract Surg"},{"key":"713_CR4","first-page":"54","volume":"17","author":"AR Vasavada","year":"2006","unstructured":"Vasavada AR, Nihalani BR (2006) Pediatric cataract surgery. Curr Opin Ophthalmol 17:54\u201361","journal-title":"Curr Opin Ophthalmol"},{"key":"713_CR5","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1098\/rstb.2010.0300","volume":"366","author":"R Michael","year":"2011","unstructured":"Michael R, Bron AJ (2011) The ageing lens and cataract: a model of normal and pathological ageing. Philos Trans R Soc Lond B Biol Sci 366:1278\u20131292","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"713_CR6","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1096\/fasebj.9.12.7672510","volume":"9","author":"A Spector","year":"1995","unstructured":"Spector A (1995) Oxidative stress-induced cataract: mechanism of action. FASEB J 9:1173\u20131182","journal-title":"FASEB J"},{"key":"713_CR7","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1016\/j.exer.2004.12.007","volume":"80","author":"RJ Truscott","year":"2005","unstructured":"Truscott RJ (2005) Age-related nuclear cataract-oxidation is the key. Exp Eye Res 80:709\u2013725","journal-title":"Exp Eye Res"},{"key":"713_CR8","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1016\/S0002-9394(14)76729-7","volume":"112","author":"BR Straatsma","year":"1991","unstructured":"Straatsma BR, Lightfoot DO, Barke RM, Horwitz J (1991) Lens capsule and epithelium in age-related cataract. Am J Ophthalmol 112:283\u2013296","journal-title":"Am J Ophthalmol"},{"key":"713_CR9","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1016\/S0886-3350(99)00009-7","volume":"25","author":"CK Joo","year":"1999","unstructured":"Joo CK, Lee EH, Kim JC, Kim YH, Lee JH, Kim JT, Chung KH, Kim J (1999) Degeneration and trans differentiation of human lens epithelial cells in nuclear and anterior polar cataracts. J Cataract Refract Surg 25:652\u2013658","journal-title":"J Cataract Refract Surg"},{"key":"713_CR10","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1177\/112067210501500206","volume":"15","author":"A Charakidas","year":"2005","unstructured":"Charakidas A, Kalogeraki A, Tsilimbaris M, Koukoulomatis P, Brouzas D, Delides G (2005) Lens epithelial apoptosis and cell proliferation in human age-related cortical cataract. Eur J Ophthalmol 15:213\u2013220","journal-title":"Eur J Ophthalmol"},{"key":"713_CR11","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/j.exer.2008.08.002","volume":"88","author":"BP Danysh","year":"2009","unstructured":"Danysh BP, Duncan MK (2009) The lens capsule. Exp Eye Res 88:151\u2013164","journal-title":"Exp Eye Res"},{"key":"713_CR12","doi-asserted-by":"publisher","first-page":"749","DOI":"10.1016\/S1350-9462(03)00063-6","volume":"22","author":"S Krag","year":"2003","unstructured":"Krag S, Andreassen TT (2003) Mechanical properties of the human lens capsule. Prog Retin Eye Res 22:749\u2013767","journal-title":"Prog Retin Eye Res"},{"key":"713_CR13","doi-asserted-by":"publisher","first-page":"501","DOI":"10.3109\/02713689109001758","volume":"10","author":"CM Parmigiani","year":"1991","unstructured":"Parmigiani CM, McAvoy JW (1991) The roles of laminin and fibronectin in the development of the lens capsule. Curr Eye Res 10:501\u2013511","journal-title":"Curr Eye Res"},{"key":"713_CR14","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1023\/A:1017952128502","volume":"21","author":"SP Bhat","year":"2001","unstructured":"Bhat SP (2001) The ocular lens epithelium. Biosci Rep 21:537\u2013563","journal-title":"Biosci Rep"},{"key":"713_CR15","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1111\/aos.12902","volume":"94","author":"S Andjelic","year":"2016","unstructured":"Andjelic S, Dra\u0161lar K, Hvala A, Lopic N, Strancar J, Hawlina M (2016) Anterior lens epithelial cells attachment to the basal lamina. Acta Ophthalmol 94:183\u2013188","journal-title":"Acta Ophthalmol"},{"key":"713_CR16","doi-asserted-by":"publisher","first-page":"635","DOI":"10.1111\/aos.12376","volume":"92","author":"LM Meyer","year":"2014","unstructured":"Meyer LM, Wegener AR, Holz FG, Kronschl\u00e4ger M, Bergmanson JP, Soderberg PG (2014) Ultrastructure of UVR-B-induced cataract and repair visualized with electron microscopy. Acta Ophthalmol 92:635\u2013643","journal-title":"Acta Ophthalmol"},{"key":"713_CR17","first-page":"369","volume":"104","author":"A Synder","year":"2002","unstructured":"Synder A, Omulecka A, Ratynska M, Omulecki W (2002) A study of human lens epithelial cells by light and electron microscopy and by immunohistochemistry in different types of cataracts. Klin Oczna 104:369\u2013373","journal-title":"Klin Oczna"},{"key":"713_CR18","first-page":"556","volume":"86","author":"H Bleckmann","year":"1989","unstructured":"Bleckmann H, Khodadadyan C, Schnoy N (1989) Light\u00a0and\u00a0electron microscopy\u00a0of the\u00a0human,\u00a0anterior\u00a0cataract\u00a0capsule. Fortschr Ophthalmol 86:556\u2013560","journal-title":"Fortschr Ophthalmol"},{"key":"713_CR19","doi-asserted-by":"publisher","first-page":"75","DOI":"10.2535\/ofaj1936.74.2-3_75","volume":"74","author":"MF Sargon","year":"1997","unstructured":"Sargon MF, Celik HH, Orhan M (1997) Electron microscopy of the senile changes in lens epithelium. Okajimas Folia Anat Jpn 74:75\u201379","journal-title":"Okajimas Folia Anat Jpn"},{"key":"713_CR20","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1016\/S0886-3350(13)80415-4","volume":"17","author":"AR Vasavada","year":"1991","unstructured":"Vasavada AR, Cherian M, Yadav S, Rawal UM (1991) Lens epithelial cell density and histomorphological study in cataractous lenses. J Cataract Refract Surg 17:798\u2013804","journal-title":"J Cataract Refract Surg"},{"key":"713_CR21","doi-asserted-by":"publisher","first-page":"269","DOI":"10.1007\/s00417-015-3220-y","volume":"254","author":"S Andjelic","year":"2016","unstructured":"Andjelic S, Dra\u0161lar K, Hvala A, Hawlina M (2016) Anterior\u00a0lens\u00a0epithelium\u00a0in intumescent white cataracts-\u00a0scanning\u00a0and\u00a0transmission\u00a0electron microscopy\u00a0study. Graefes Arch Clin Exp Ophthalmol 254:269\u2013276","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"713_CR22","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1111\/aos.13250","volume":"95","author":"S Andjelic","year":"2017","unstructured":"Andjelic S, Draslar K, Hvala A, Hawlina M (2017) Anterior lens epithelium in cataract patients with retinitis pigmentosa\u2014scanning and transmission electron microscopy study. Acta Ophthalmol 95:212\u2013220","journal-title":"Acta Ophthalmol"},{"key":"713_CR23","doi-asserted-by":"publisher","first-page":"118","DOI":"10.4103\/0973-7847.70902","volume":"4","author":"V Lobo","year":"2010","unstructured":"Lobo V, Patil A, Phatak A, Chandra N (2010) Free radicals, antioxidants and functional foods: impact on human health. Pharmacogn Rev 4:118\u2013126","journal-title":"Pharmacogn Rev"},{"key":"713_CR24","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.exer.2014.09.005","volume":"129","author":"BR Hammond","year":"2014","unstructured":"Hammond BR, Johnson BA, George ER (2014) Oxidative photodegradation of ocular tissues: beneficial effects of filtering and exogenous antioxidants. Exp Eye Res 129:135\u2013150","journal-title":"Exp Eye Res"},{"key":"713_CR25","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/0014-4835(83)90145-8","volume":"37","author":"HM Cheng","year":"1983","unstructured":"Cheng HM, Fagerholm P, Chylack LT Jr. (1983) Response of the lens to oxidative-osmotic stress. Exp Eye Res 37:11\u201321","journal-title":"Exp Eye Res"},{"key":"713_CR26","doi-asserted-by":"publisher","first-page":"3164734","DOI":"10.1155\/2016\/3164734","volume":"2016","author":"M Nita","year":"2016","unstructured":"Nita M, Grzybowski A (2016) The role of the reactive oxygen species and\u00a0oxidative stress\u00a0in the pathomechanism of the age-related ocular diseases and other pathologies of the anterior and posterior eye segments in adults. Oxid Med Cell Longev 2016:3164734","journal-title":"Oxid Med Cell Longev"},{"key":"713_CR27","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1089\/ars.2008.2119","volume":"11","author":"VM Berthoud","year":"2009","unstructured":"Berthoud VM, Beyer EC (2009) Oxidative stress, lens gap junctions, and cataracts. Antioxid Redox Signal 11:339\u2013353","journal-title":"Antioxid Redox Signal"},{"key":"713_CR28","first-page":"167","volume-title":"Diseases of the lens, comprehensive ophthalmology","author":"AK Khurana","year":"2007","unstructured":"Khurana AK (2007) Diseases of the lens, comprehensive ophthalmology, 4th edn. New Age International (P) Ltd, New Delhi, pp 167\u2013204","edition":"4"},{"key":"713_CR29","doi-asserted-by":"publisher","first-page":"2292","DOI":"10.1016\/j.ophtha.2004.06.024","volume":"111","author":"B Haargard","year":"2004","unstructured":"Haargard B, Wohlfahrt J, Fledelius HC, Rosenberg T, Melbye M (2004) A nationwide Danish study of 1027 cases of congenital\/infantile cataracts: etiological and clinical classifications. Ophthalmology 111:2292\u20132298","journal-title":"Ophthalmology"},{"key":"713_CR30","doi-asserted-by":"publisher","first-page":"103","DOI":"10.4103\/0301-4738.121141","volume":"62","author":"VB Gupta","year":"2014","unstructured":"Gupta VB, Rajagopala M, Ravishankar B (2014) Etiopathogenesis of cataract: an appraisal. Indian J Ophthalmol 62:103\u2013110","journal-title":"Indian J Ophthalmol"},{"key":"713_CR31","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1016\/j.ophtha.2009.12.026","volume":"117","author":"SG Prakalapakom","year":"2010","unstructured":"Prakalapakom SG, Rasmussen SA, Lambert SR, Honein MA, National Birth Defects Prevention Study (2010) Assessment of risk factors for infantile cataracts using a case-control study: National Birth Defects Prevention Study, 2000\u20132004. Ophthalmology 117:1500\u20131505","journal-title":"Ophthalmology"},{"key":"713_CR32","doi-asserted-by":"publisher","first-page":"184","DOI":"10.1038\/eye.1992.37","volume":"6","author":"IC Lloyd","year":"1992","unstructured":"Lloyd IC, Goss-Sampson M, Jeffrey BG, Kriss A, Russell-Eggitt I, Taylor D (1992) Neonatal cataract: aetiology, pathogenesis and management. Eye (Lond) 6:184\u2013196","journal-title":"Eye (Lond)"},{"key":"713_CR33","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1159\/000333219","volume":"48","author":"S Stunf","year":"2012","unstructured":"Stunf S, Hvala A, Vidovi\u010d Valentin\u010di\u010d N, Kraut A, Hawlina M (2012) Ultrastructure of the anterior lens capsule and epithelium in cataracts associated with uveitis. Ophthalmic Res 48:12\u201321","journal-title":"Ophthalmic Res"}],"updated-by":[{"DOI":"10.1007\/s10792-025-03916-5","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T00:00:00Z","timestamp":1769472000000}}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-017-0713-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-017-0713-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-017-0713-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T03:53:41Z","timestamp":1769486021000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-017-0713-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,23]]},"references-count":33,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,10]]}},"alternative-id":["713"],"URL":"https:\/\/doi.org\/10.1007\/s10792-017-0713-1","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"value":"0165-5701","type":"print"},{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,23]]},"assertion":[{"value":"31 January 2017","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 September 2017","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2017","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 December 2025","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original online version of this article was revised due to update in the figure.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 January 2026","order":8,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":9,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":10,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10792-025-03916-5","URL":"https:\/\/doi.org\/10.1007\/s10792-025-03916-5","order":11,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers\u2019 bureaus; membership, employment, consultancies, stock ownership or other equity interest; and expert testimony or patent-licensing arrangements) or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}