{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:16:40Z","timestamp":1763018200791,"version":"3.37.3"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T00:00:00Z","timestamp":1593734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1007\/s10792-020-01500-7","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T14:03:34Z","timestamp":1593785014000},"page":"3135-3143","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Relationship between vascular densities of choriocapillaris and the whole choroid using OCTA"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4476-6003","authenticated-orcid":false,"given":"Francisco de As\u00eds","family":"Bartol-Puyal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Isanta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"Calvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d3scar","family":"Ruiz-Moreno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Pablo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,3]]},"reference":[{"key":"1500_CR1","doi-asserted-by":"publisher","first-page":"4710","DOI":"10.1364\/OE.20.004710","volume":"20","author":"Y Jia","year":"2012","unstructured":"Jia Y, Tan O, Tokayer J et al (2012) Split-spectrum amplitude-decorrelation angiography with optical coherence tomography. Opt Express 20:4710\u20134725","journal-title":"Opt Express"},{"key":"1500_CR2","first-page":"13","volume-title":"Developments in ophthalmology","author":"PE Stanga","year":"2016","unstructured":"Stanga PE, Tsamis E, Papayannis A et al (2016) Swept-source optical coherence tomography angioTM (Topcon Corp, Japan): technology review. In: Bandello F (ed) Developments in ophthalmology. Karger Publishers, Basel, pp 13\u201317"},{"key":"1500_CR3","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.preteyeres.2009.12.002","volume":"29","author":"DL Nickla","year":"2010","unstructured":"Nickla DL, Wallman J (2010) The multifunctional choroid. Prog Retin Eye Res 29:144\u2013168. https:\/\/doi.org\/10.1016\/j.preteyeres.2009.12.002","journal-title":"Prog Retin Eye Res"},{"key":"1500_CR4","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1016\/j.preteyeres.2012.04.004","volume":"31","author":"J Kur","year":"2012","unstructured":"Kur J, Newman EA, Chan-Ling T (2012) Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease. Prog Retin Eye Res 31:377\u2013406. https:\/\/doi.org\/10.1016\/j.preteyeres.2012.04.004","journal-title":"Prog Retin Eye Res"},{"key":"1500_CR5","doi-asserted-by":"publisher","first-page":"1670","DOI":"10.1097\/IAE.0000000000001085","volume":"36","author":"EAT Say","year":"2016","unstructured":"Say EAT, Samara WA, Khoo CTL et al (2016) Parafoveal capillary density after plaque radiotherapy for choroidal melanoma: analysis of eyes without radiation maculopathy. Retina 36:1670\u20131678","journal-title":"Retina"},{"key":"1500_CR6","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1016\/j.ajo.2015.03.005","volume":"159","author":"S Sonoda","year":"2015","unstructured":"Sonoda S, Sakamoto T, Yamashita T et al (2015) Luminal and stromal areas of choroid determined by binarization method of optical coherence tomographic images. Am J Ophthalmol 159:1123\u20131131.e1","journal-title":"Am J Ophthalmol"},{"key":"1500_CR7","doi-asserted-by":"publisher","first-page":"508","DOI":"10.1097\/IAE.0000000000001571","volume":"38","author":"J Ruiz-Medrano","year":"2018","unstructured":"Ruiz-Medrano J, Ruiz-Moreno JM, Goud A et al (2018) Age-related changes in choroidal vascular density of healthy subjects based on image binarization of swept-source optical coherence tomography. Retina 38:508\u2013515","journal-title":"Retina"},{"key":"1500_CR8","doi-asserted-by":"publisher","first-page":"1524","DOI":"10.1136\/bjophthalmol-2016-309628","volume":"101","author":"K Sayanagi","year":"2017","unstructured":"Sayanagi K, Ikuno Y, Uematsu S, Nishida K (2017) Features of the choriocapillaris in myopic maculopathy identified by optical coherence tomography angiography. Br J Ophthalmol 101:1524\u20131529. https:\/\/doi.org\/10.1136\/bjophthalmol-2016-309628","journal-title":"Br J Ophthalmol"},{"key":"1500_CR9","doi-asserted-by":"publisher","first-page":"2063","DOI":"10.1167\/iovs.16-21289","volume":"58","author":"M Al-Sheikh","year":"2017","unstructured":"Al-Sheikh M, Phasukkijwatana N, Dolz-Marco R et al (2017) Quantitative OCT angiography of the retinal microvasculature and the choriocapillaris in myopic eyes. Investig Opthalmology Vis Sci 58:2063. https:\/\/doi.org\/10.1167\/iovs.16-21289","journal-title":"Investig Opthalmology Vis Sci"},{"key":"1500_CR10","doi-asserted-by":"publisher","first-page":"4792","DOI":"10.1167\/iovs.17-22360","volume":"58","author":"E Borrelli","year":"2017","unstructured":"Borrelli E, Uji A, Sarraf D, Sadda SR (2017) Alterations in the choriocapillaris in intermediate age-related macular degeneration. Investig Opthalmology Vis Sci 58:4792. https:\/\/doi.org\/10.1167\/iovs.17-22360","journal-title":"Investig Opthalmology Vis Sci"},{"key":"1500_CR11","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1007\/s10792-017-0671-7","volume":"38","author":"I Chatziralli","year":"2018","unstructured":"Chatziralli I, Theodossiadis G, Panagiotidis D et al (2018) Choriocapillaris\u2019 alterations in the presence of reticular pseudodrusen compared to drusen: study based on OCTA findings. Int Ophthalmol 38:1887\u20131893. https:\/\/doi.org\/10.1007\/s10792-017-0671-7","journal-title":"Int Ophthalmol"},{"key":"1500_CR12","doi-asserted-by":"publisher","first-page":"2353","DOI":"10.1097\/IAE.0000000000000862","volume":"35","author":"SA Agemy","year":"2015","unstructured":"Agemy SA, Scripsema NK, Shah CM et al (2015) Retinal vascular perfusion density mapping using optical coherence tomography angiography in normals and diabetic retinopathy patients. Retina 35:2353\u20132363","journal-title":"Retina"},{"key":"1500_CR13","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1159\/000448436","volume":"236","author":"A Shinojima","year":"2016","unstructured":"Shinojima A, Kawamura A, Mori R et al (2016) Findings of optical coherence tomographic angiography at the choriocapillaris level in central serous chorioretinopathy. Ophthalmologica 236:108\u2013113. https:\/\/doi.org\/10.1159\/000448436","journal-title":"Ophthalmologica"},{"key":"1500_CR14","doi-asserted-by":"publisher","first-page":"2468","DOI":"10.3390\/ijms18112468","volume":"18","author":"M Nassisi","year":"2017","unstructured":"Nassisi M, Lavia C, Alovisi C et al (2017) Short-term choriocapillaris changes in patients with central serous chorioretinopathy after half-dose photodynamic therapy. Int J Mol Sci 18:2468. https:\/\/doi.org\/10.3390\/ijms18112468","journal-title":"Int J Mol Sci"},{"key":"1500_CR15","doi-asserted-by":"publisher","first-page":"302","DOI":"10.3928\/23258160-20170329-04","volume":"48","author":"K Fujita","year":"2017","unstructured":"Fujita K, Kawamura A, Yuzawa M (2017) Choriocapillaris changes imaged by OCT angiography after half-dose photodynamic therapy for chronic central serous chorioretinopathy. Ophthalmic Surg Lasers Imaging Retin 48:302\u2013310. https:\/\/doi.org\/10.3928\/23258160-20170329-04","journal-title":"Ophthalmic Surg Lasers Imaging Retin"},{"key":"1500_CR16","doi-asserted-by":"publisher","first-page":"OCT356","DOI":"10.1167\/iovs.15-18473","volume":"57","author":"ED Cole","year":"2016","unstructured":"Cole ED, Novais EA, Louzada RN et al (2016) Visualization of changes in the choriocapillaris, choroidal vessels and retinal morphology after focal laser photocoagulation using OCT angiography. Investig Opthalmology Vis Sci 57:OCT356. https:\/\/doi.org\/10.1167\/iovs.15-18473","journal-title":"Investig Opthalmology Vis Sci"},{"key":"1500_CR17","doi-asserted-by":"publisher","first-page":"322","DOI":"10.3928\/23258160-20160324-03","volume":"47","author":"N Feucht","year":"2016","unstructured":"Feucht N, Maier M, Lohmann CP, Reznicek L (2016) OCT angiography findings in acute central serous chorioretinopathy. Ophthalmic Surgery, Lasers Imaging Retin 47:322\u2013327. https:\/\/doi.org\/10.3928\/23258160-20160324-03","journal-title":"Ophthalmic Surgery, Lasers Imaging Retin"},{"key":"1500_CR18","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s40942-015-0005-8","volume":"1","author":"TE de Carlo","year":"2015","unstructured":"de Carlo TE, Romano A, Waheed NK, Duker JS (2015) A review of optical coherence tomography angiography (OCTA). Int J Retin Vitr 1:5","journal-title":"Int J Retin Vitr"},{"key":"1500_CR19","doi-asserted-by":"publisher","first-page":"1411","DOI":"10.1001\/jamaophthalmol.2016.4272","volume":"134","author":"TS Hwang","year":"2016","unstructured":"Hwang TS, Zhang M, Bhavsar K et al (2016) Visualization of 3 distinct retinal plexuses by projection-resolved optical coherence tomography angiography in diabetic retinopathy. JAMA Ophthalmol 134:1411","journal-title":"JAMA Ophthalmol"},{"key":"1500_CR20","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1111\/ceo.12683","volume":"44","author":"FK Chen","year":"2016","unstructured":"Chen FK, Viljoen RD, Bukowska DM (2016) Classification of image artefacts in optical coherence tomography angiography of the choroid in macular diseases. Clin Experiment Ophthalmol 44:388\u2013399. https:\/\/doi.org\/10.1111\/ceo.12683","journal-title":"Clin Experiment Ophthalmol"},{"key":"1500_CR21","doi-asserted-by":"publisher","first-page":"9853","DOI":"10.1038\/s41598-017-09255-5","volume":"7","author":"H Shiihara","year":"2017","unstructured":"Shiihara H, Sakamoto T, Yamashita T et al (2017) Reproducibility and differences in area of foveal avascular zone measured by three different optical coherence tomographic angiography instruments. Sci Rep 7:9853. https:\/\/doi.org\/10.1038\/s41598-017-09255-5","journal-title":"Sci Rep"},{"key":"1500_CR22","doi-asserted-by":"publisher","first-page":"e0177059","DOI":"10.1371\/journal.pone.0177059","volume":"12","author":"MR Munk","year":"2017","unstructured":"Munk MR, Giannakaki-Zimmermann H, Berger L et al (2017) OCT-angiography: a qualitative and quantitative comparison of 4 OCT-A devices. PLoS ONE 12:e0177059. https:\/\/doi.org\/10.1371\/journal.pone.0177059","journal-title":"PLoS ONE"},{"key":"1500_CR23","doi-asserted-by":"publisher","first-page":"623","DOI":"10.3928\/23258160-20170802-04","volume":"48","author":"M Al-Sheikh","year":"2017","unstructured":"Al-Sheikh M, Falavarjani KG, Pfau M et al (2017) Quantitative features of the choriocapillaris in healthy individuals using swept-source optical coherence tomography angiography. Ophthalmic Surg Lasers Imaging Retina 48:623\u2013631. https:\/\/doi.org\/10.3928\/23258160-20170802-04","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"1500_CR24","doi-asserted-by":"publisher","first-page":"452","DOI":"10.1136\/bjophthalmol-2018-311903","volume":"103","author":"FF Conti","year":"2019","unstructured":"Conti FF, Qin VL, Rodrigues EB et al (2019) Choriocapillaris and retinal vascular plexus density of diabetic eyes using split-spectrum amplitude decorrelation spectral-domain optical coherence tomography angiography. Br J Ophthalmol 103:452\u2013456. https:\/\/doi.org\/10.1136\/bjophthalmol-2018-311903","journal-title":"Br J Ophthalmol"},{"key":"1500_CR25","doi-asserted-by":"publisher","first-page":"95","DOI":"10.1016\/j.ajo.2016.05.005","volume":"168","author":"Q Wang","year":"2016","unstructured":"Wang Q, Chan S, Yang JY et al (2016) Vascular density in retina and choriocapillaris as measured by optical coherence tomography angiography. Am J Ophthalmol 168:95\u2013109. https:\/\/doi.org\/10.1016\/j.ajo.2016.05.005","journal-title":"Am J Ophthalmol"},{"key":"1500_CR26","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1177\/1120672118816225","volume":"1","author":"J Oh","year":"2020","unstructured":"Oh J, Baik DJ, Ahn J (2020) Inter-relationship between retinal and choroidal vasculatures using optical coherence tomography angiography in normal eyes. Eur J Ophthalmol 1:48\u201357","journal-title":"Eur J Ophthalmol"},{"key":"1500_CR27","doi-asserted-by":"publisher","first-page":"1352","DOI":"10.1167\/iovs.13-13754","volume":"55","author":"EH Sohn","year":"2014","unstructured":"Sohn EH, Khanna A, Tucker BA et al (2014) Structural and biochemical analyses of choroidal thickness in human donor eyes. Invest Ophthalmol Vis Sci 55:1352\u20131360. https:\/\/doi.org\/10.1167\/iovs.13-13754","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"1500_CR28","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1369\/jhc.2008.952531","volume":"57","author":"AM Macgregor","year":"2009","unstructured":"Macgregor AM, Eberhart CG, Fraig M et al (2009) Tissue inhibitor of matrix metalloproteinase-3 levels in the extracellular matrix of lung, kidney, and eye increase with age. J Histochem Cytochem 57:207\u2013213. https:\/\/doi.org\/10.1369\/jhc.2008.952531","journal-title":"J Histochem Cytochem"},{"key":"1500_CR29","doi-asserted-by":"publisher","first-page":"1329","DOI":"10.1136\/bjo.82.11.1329","volume":"82","author":"RN Fariss","year":"1998","unstructured":"Fariss RN, Apte SS, Luthert PJ et al (1998) Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby\u2019s fundus dystrophy or retinitis pigmentosa. Br J Ophthalmol 82:1329\u20131334","journal-title":"Br J Ophthalmol"},{"key":"1500_CR30","doi-asserted-by":"publisher","first-page":"2812","DOI":"10.1167\/iovs.07-1444","volume":"49","author":"A Janssen","year":"2008","unstructured":"Janssen A, Hoellenriegel J, Fogarasi M et al (2008) Abnormal vessel formation in the choroid of mice lacking tissue inhibitor of metalloprotease-3. Investig Opthalmology Vis Sci 49:2812. https:\/\/doi.org\/10.1167\/iovs.07-1444","journal-title":"Investig Opthalmology Vis Sci"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01500-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-020-01500-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01500-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,3]],"date-time":"2021-07-03T00:49:41Z","timestamp":1625273381000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-020-01500-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,3]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["1500"],"URL":"https:\/\/doi.org\/10.1007\/s10792-020-01500-7","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"type":"print","value":"0165-5701"},{"type":"electronic","value":"1573-2630"}],"subject":[],"published":{"date-parts":[[2020,7,3]]},"assertion":[{"value":"28 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 June 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Ethics approval by the Comit\u00e9 de \u00c9tica de la Investigaci\u00f3n de la Comunidad Aut\u00f3noma de Arag\u00f3n.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All patients agreed to participate.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}]}}