{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T03:08:57Z","timestamp":1774321737276,"version":"3.50.1"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T00:00:00Z","timestamp":1595808000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s10792-020-01520-3","type":"journal-article","created":{"date-parts":[[2020,7,27]],"date-time":"2020-07-27T07:03:52Z","timestamp":1595833432000},"page":"3337-3348","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Assessment of Doppler flow parameters of the retrobulbar arteries and internal carotid artery in patients with glaucoma: the significance of ophthalmic artery peak ratio and the intima\u2013media thickness of the internal carotid artery"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8056-6634","authenticated-orcid":false,"given":"Mustafa","family":"Kalayci","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9668-8062","authenticated-orcid":false,"given":"Mehmet","family":"Tahtabasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,27]]},"reference":[{"key":"1520_CR1","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1016\/S0140-6736(17)31469-1","volume":"390","author":"JB Jonas","year":"2017","unstructured":"Jonas JB, Aung T, Bourne RR, Bron AM, Ritch R, Panda-Jonas S (2017) Glaucoma. Lancet 390:2183\u20132193","journal-title":"Lancet"},{"key":"1520_CR2","doi-asserted-by":"crossref","first-page":"e1221","DOI":"10.1016\/S2214-109X(17)30393-5","volume":"5","author":"SR Flaxman","year":"2017","unstructured":"Flaxman SR, Bourne RRA, Resnikoff S et al (2017) Global causes of blindness and distance vision impairment 1990\u20132020: a systematic review and meta-analysis. Lancet Glob Heal 5:e1221\u2013e1234","journal-title":"Lancet Glob Heal"},{"key":"1520_CR3","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","volume":"121","author":"YC Tham","year":"2014","unstructured":"Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. Ophthalmology 121:2081\u20132090","journal-title":"Ophthalmology"},{"key":"1520_CR4","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/S1350-9462(02)00008-3","volume":"21","author":"J Flammer","year":"2002","unstructured":"Flammer J, Org\u00fcl S, Costa VP, Orzalesi N, Krieglstein GK, Serra LM, Renard J-P, Stef\u00e1nsson E (2002) The impact of ocular blood flow in glaucoma. Prog Retin Eye Res 21:359\u2013393","journal-title":"Prog Retin Eye Res"},{"key":"1520_CR5","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1177\/112067210901900410","volume":"19","author":"I Stalmans","year":"2009","unstructured":"Stalmans I, Harris A, Fieuws S, Zeyen T, Vanbellinghen V, McCranor L, Siesky B (2009) Color Doppler imaging and ocular pulse amplitude in glaucomatous and healthy eyes. Eur J Ophthalmol 19:580\u2013587","journal-title":"Eur J Ophthalmol"},{"key":"1520_CR6","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1111\/aos.12962","volume":"94","author":"L Abeg\u00e3o Pinto","year":"2016","unstructured":"Abeg\u00e3o Pinto L, Willekens K, Van Keer K, Shibesh A, Molenberghs G, Vandewalle E, Stalmans I (2016) Ocular blood flow in glaucoma\u2014the Leuven Eye Study. Acta Ophthalmol 94:592\u2013598","journal-title":"Acta Ophthalmol"},{"key":"1520_CR7","first-page":"21","volume":"4","author":"G Michelson","year":"1995","unstructured":"Michelson G, Groh MJ, Groh ME, Gr\u00fcndler A (1995) Advanced primary open-angle glaucoma is associated with decreased ophthalmic artery blood-flow velocity. Ger J Ophthalmol 4:21\u201324","journal-title":"Ger J Ophthalmol"},{"key":"1520_CR8","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.3109\/14767058.2015.1040755","volume":"29","author":"JA Gurgel Alves","year":"2016","unstructured":"Gurgel Alves JA, Maia e Holanda Moura SB, Araujo J\u00fanior E, Tonni G, Martins WP, Da Silva Costa F (2016) Predicting small for gestational age in the first trimester of pregnancy using maternal ophthalmic artery Doppler indices. J Matern Neonatal Med 29:1190\u20131194","journal-title":"J Matern Neonatal Med"},{"key":"1520_CR9","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.preghy.2017.10.006","volume":"10","author":"MTP Chaves","year":"2017","unstructured":"Chaves MTP, Martins-Costa S, da Oppermann MLR, Dias RP, Magno V, Pe\u00f1a JA, Ramos JGL (2017) Maternal ophthalmic artery Doppler ultrasonography in preeclampsia and pregnancy outcomes. Pregn Hypertens 10:242\u2013246","journal-title":"Pregn Hypertens"},{"key":"1520_CR10","doi-asserted-by":"crossref","first-page":"609","DOI":"10.7863\/jum.2013.32.4.609","volume":"32","author":"CA de Oliveira","year":"2013","unstructured":"de Oliveira CA, de S\u00e1 RAM, Velarde LGC, da Silva FC, do Vale FA, Netto HC (2013) Changes in ophthalmic artery doppler indices in hypertensive disorders during pregnancy. J Ultrasound Med 32:609\u2013619","journal-title":"J Ultrasound Med"},{"key":"1520_CR11","first-page":"931","volume":"100","author":"M Takata","year":"2002","unstructured":"Takata M, Nakatsuka M, Kudo T (2002) Differential blood flow in uterine, ophthalmic, and brachial arteries of preeclamptic women. Obstet Gynecol 100:931\u2013939","journal-title":"Obstet Gynecol"},{"key":"1520_CR12","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.rcl.2019.01.008","volume":"57","author":"LM Scoutt","year":"2019","unstructured":"Scoutt LM, Gunabushanam G (2019) Carotid ultrasound. Radiol Clin North Am 57:501\u2013518","journal-title":"Radiol Clin North Am"},{"key":"1520_CR13","doi-asserted-by":"crossref","first-page":"2448","DOI":"10.1167\/iovs.11-9388","volume":"53","author":"LA Pinto","year":"2012","unstructured":"Pinto LA, Vandewalle E, de Clerck E, Marques-Neves C, Stalmans I (2012) Ophthalmic Artery Doppler waveform changes associated with increased damage in glaucoma patients. Investig Ophthalmol Vis Sci 53:2448\u20132453","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"1520_CR14","doi-asserted-by":"crossref","first-page":"e609","DOI":"10.1111\/j.1755-3768.2011.02178.x","volume":"89","author":"I Stalmans","year":"2011","unstructured":"Stalmans I, Vandewalle E, Anderson DR et al (2011) Use of colour Doppler imaging in ocular blood flow research. Acta Ophthalmol 89:e609\u2013e630","journal-title":"Acta Ophthalmol"},{"key":"1520_CR15","doi-asserted-by":"crossref","first-page":"309","DOI":"10.7863\/jum.2002.21.3.309","volume":"21","author":"M Nakatsuka","year":"2002","unstructured":"Nakatsuka M, Takata M, Tada K, Kudo T (2002) Effect of a nitric oxide donor on the ophthalmic artery flow velocity waveform in preeclamptic women. J Ultrasound Med 21:309\u2013313","journal-title":"J Ultrasound Med"},{"key":"1520_CR16","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/S0161-6420(00)00138-X","volume":"107","author":"L Bonomi","year":"2000","unstructured":"Bonomi L (2000) Vascular risk factors for primary open angle glaucoma :The Egna-Neumarkt study. Ophthalmology 107:1287\u20131293","journal-title":"Ophthalmology"},{"key":"1520_CR17","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/j.ophtha.2007.03.016","volume":"114","author":"MC Leske","year":"2007","unstructured":"Leske MC, Heijl A, Hyman L, Bengtsson B, Dong L, Yang Z (2007) Predictors of long-term progression in the early manifest glaucoma trial. Ophthalmology 114:1965\u20131972","journal-title":"Ophthalmology"},{"key":"1520_CR18","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1001\/archopht.120.10.1268","volume":"120","author":"A Heijl","year":"2002","unstructured":"Heijl A (2002) Reduction of intraocular pressure and glaucoma progression. Arch Ophthalmol 120:1268","journal-title":"Arch Ophthalmol"},{"key":"1520_CR19","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1136\/bjo.34.1.47","volume":"34","author":"E Dienstbier","year":"1950","unstructured":"Dienstbier E, Balik J, Kafka H (1950) A contribution to the theory of the vascular origin of glaucoma. Br J Ophthalmol 34:47\u201358","journal-title":"Br J Ophthalmol"},{"key":"1520_CR20","first-page":"1","volume":"2015","author":"S Xu","year":"2015","unstructured":"Xu S, Huang S, Lin Z, Liu W, Zhong Y (2015) Color Doppler imaging analysis of ocular blood flow velocities in normal tension glaucoma patients: a meta-analysis. J Ophthalmol 2015:1\u201324","journal-title":"J Ophthalmol"},{"key":"1520_CR21","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ophtha.2007.03.017","volume":"115","author":"MC Leske","year":"2008","unstructured":"Leske MC, Wu S-Y, Hennis A, Honkanen R, Nemesure B (2008) Risk factors for incident open-angle glaucoma. Ophthalmology 115:85\u201393","journal-title":"Ophthalmology"},{"key":"1520_CR22","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1001\/archopht.119.12.1819","volume":"119","author":"HA Quigley","year":"2001","unstructured":"Quigley HA (2001) The prevalence of glaucoma in a population-based study of hispanic subjects. Arch Ophthalmol 119:1819","journal-title":"Arch Ophthalmol"},{"key":"1520_CR23","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.coph.2012.09.003","volume":"13","author":"AP Cherecheanu","year":"2013","unstructured":"Cherecheanu AP, Garhofer G, Schmidl D, Werkmeister R, Schmetterer L (2013) Ocular perfusion pressure and ocular blood flow in glaucoma. Curr Opin Pharmacol 13:36\u201342","journal-title":"Curr Opin Pharmacol"},{"key":"1520_CR24","doi-asserted-by":"crossref","first-page":"124","DOI":"10.5301\/ejo.5000671","volume":"26","author":"T Kocaturk","year":"2016","unstructured":"Kocaturk T, Isikligil I, Uz B, Dayanir V, Dayanir YO (2016) Ophthalmic artery blood flow parameters in pseudoexfoliation glaucoma. Eur J Ophthalmol 26:124\u2013127","journal-title":"Eur J Ophthalmol"},{"key":"1520_CR25","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/jcu.20137","volume":"33","author":"N Akcar","year":"2005","unstructured":"Akcar N, Y\u0131ld\u0131r\u0131m N, Adap\u0131nar B, Kaya T, Ozkan IR (2005) Duplex sonography of retro-orbital and carotid arteries in patients with normal-tension glaucoma. J Clin Ultrasound 33:270\u2013276","journal-title":"J Clin Ultrasound"},{"key":"1520_CR26","doi-asserted-by":"crossref","first-page":"679","DOI":"10.4103\/0971-3026.32298","volume":"16","author":"N Sharma","year":"2006","unstructured":"Sharma N, Bangiya D (2006) Comparative study of ocular blood flow parameters by color doppler imaging in healthy and glaucomatous eye. Indian J Radiol Imaging 16:679","journal-title":"Indian J Radiol Imaging"},{"key":"1520_CR27","doi-asserted-by":"crossref","first-page":"563","DOI":"10.7863\/jum.2009.28.5.563","volume":"28","author":"CA de Oliveira","year":"2009","unstructured":"de Oliveira CA, de S\u00e1 RAM, Velarde LGC, Marchiori E, Netto HC, Ville Y (2009) Doppler velocimetry of the ophthalmic artery in normal pregnancy. J Ultrasound Med 28:563\u2013569","journal-title":"J Ultrasound Med"},{"key":"1520_CR28","doi-asserted-by":"crossref","first-page":"174","DOI":"10.4103\/0974-9233.110617","volume":"20","author":"OO Adeyinka","year":"2013","unstructured":"Adeyinka OO, Olugbenga A, Helen OO, Adebayo AV, Rasheed A (2013) Ocular blood flow velocity in primary open angle glaucoma\u2014a tropical african population study. Middle East Afr J Ophthalmol 20:174\u2013178","journal-title":"Middle East Afr J Ophthalmol"},{"key":"1520_CR29","doi-asserted-by":"crossref","unstructured":"American Diabetes Association (2014) Diagnosis and classification of diabetes mellitus. Diab Care 37: S81\u2013S90","DOI":"10.2337\/dc14-S081"},{"key":"1520_CR30","first-page":"417","volume":"30","author":"M Unay","year":"2000","unstructured":"Unay M, K\u00fc\u00e7\u00fckg\u00fcl S, Yararcan M, \u00d6ziz E\u00c7Z (2000) Assesment of orbital arteries blood flow rate with coloured doppler ultrasonography in primary open angle glaucoma. Turk J Ophthalmol 30:417\u2013422","journal-title":"Turk J Ophthalmol"},{"key":"1520_CR31","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/j.clineuro.2008.04.007","volume":"110","author":"M Conti","year":"2008","unstructured":"Conti M, Prevedello DM, Madhok R, Faure A, Ricci UM, Schwarz A, Robert R, Kassam AB (2008) The antero-medial triangle: the risk for cranial nerves ischemia at the cavernous sinus lateral wall. Anatomic cadaveric study. Clin Neurol Neurosurg 110:682\u2013686","journal-title":"Clin Neurol Neurosurg"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01520-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-020-01520-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01520-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T23:13:23Z","timestamp":1627341203000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-020-01520-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,27]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["1520"],"URL":"https:\/\/doi.org\/10.1007\/s10792-020-01520-3","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"value":"0165-5701","type":"print"},{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,27]]},"assertion":[{"value":"6 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All authors attest that they meet the current ICMJE criteria for authorship.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authorship"}},{"value":"Written informed consent was obtained from the patients before any examination or treatment was performed.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}