{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,31]],"date-time":"2025-12-31T00:39:02Z","timestamp":1767141542012,"version":"build-2238731810"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T00:00:00Z","timestamp":1596067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T00:00:00Z","timestamp":1596067200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"Scientific Research Project of Hebei Health Commission","award":["No. 20200069"],"award-info":[{"award-number":["No. 20200069"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2020,12]]},"DOI":"10.1007\/s10792-020-01528-9","type":"journal-article","created":{"date-parts":[[2020,7,30]],"date-time":"2020-07-30T07:28:10Z","timestamp":1596094090000},"page":"3413-3430","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Novel observations in choroidal osteoma by multispectral imaging: a pilot case series"],"prefix":"10.1007","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9662-3357","authenticated-orcid":false,"given":"Feiyan","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianhang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Igor","family":"Kozak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingli","family":"Shang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingxue","family":"Ma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,7,30]]},"reference":[{"key":"1528_CR1","unstructured":"Shields JA, SC (2016) Choroidal osteoma, 3rd ed. Atlas of Intraocular Tumors. Lippincott, Wolters Kluwer"},{"key":"1528_CR2","unstructured":"Rosa H, RM, Bloomer M, Gombos DS (2019) Ophthalmic pathology and intraocular Tumors. Basic Clin Sci Course 4"},{"issue":"1","key":"1528_CR3","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1023\/A:1014470730194","volume":"24","author":"G Gurelik","year":"2001","unstructured":"Gurelik G et al (2001) A case of choroidal osteoma with subsequent laser induced decalcification. Int Ophthalmol 24(1):41\u201344","journal-title":"Int Ophthalmol"},{"issue":"2","key":"1528_CR4","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1007\/s10792-017-0503-9","volume":"38","author":"C Shen","year":"2018","unstructured":"Shen C et al (2018) Assessment of choroidal osteoma complicating choroidal neovascularization by optical coherence tomography angiography. Int Ophthalmol 38(2):787\u2013792","journal-title":"Int Ophthalmol"},{"issue":"3","key":"1528_CR5","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1177\/1120672118792187","volume":"29","author":"C Furino","year":"2019","unstructured":"Furino C et al (2019) Choroidal neovascularization due to choroidal osteoma treated with anti-vascular endothelial growth factor therapy: an optical coherence tomography angiography study. Eur J Ophthalmol 29(3):323\u2013329","journal-title":"Eur J Ophthalmol"},{"issue":"6","key":"1528_CR6","doi-asserted-by":"publisher","first-page":"398","DOI":"10.3928\/23258160-20190605-10","volume":"50","author":"A Arrigo","year":"2019","unstructured":"Arrigo A et al (2019) Bilateral choroidal osteoma complicated by bilateral choroidal neovascularization. Ophthalmic Surg Lasers Imaging Retina 50(6):398\u2013400","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"issue":"2","key":"1528_CR7","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1007\/s10792-017-0806-x","volume":"39","author":"V Kumar","year":"2019","unstructured":"Kumar V (2019) Choroidal osteoma and pattern dystrophy of retinal pigment epithelium. Int Ophthalmol 39(2):441\u2013444","journal-title":"Int Ophthalmol"},{"issue":"7","key":"1528_CR8","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1016\/S0161-6420(03)00458-5","volume":"110","author":"DJ Browning","year":"2003","unstructured":"Browning DJ (2003) Choroidal osteoma. Ophthalmology 110(7):1327\u20131334","journal-title":"Ophthalmology"},{"issue":"3","key":"1528_CR9","doi-asserted-by":"publisher","first-page":"244","DOI":"10.4103\/0974-9233.134686","volume":"21","author":"A Mansour","year":"2014","unstructured":"Mansour A, Alameddine R, Kahtani E (2014) Review of choroidal osteomas. Middle East Afr J Ophthalmol 21(3):244\u2013250","journal-title":"Middle East Afr J Ophthalmol"},{"key":"1528_CR10","doi-asserted-by":"crossref","unstructured":"Padhy SK, Mandal S, Gagrani M (2018) Bone inside eye: choroidal osteoma presenting as exudative retinal detachment: a challenge to diagnosis. BMJ Case Reports, pp 1\u20132","DOI":"10.1136\/bcr-2018-225393"},{"issue":"9","key":"1528_CR11","doi-asserted-by":"publisher","first-page":"1841","DOI":"10.1016\/S0161-6420(99)90363-9","volume":"106","author":"DHK Jokl","year":"1999","unstructured":"Jokl DHK, Tsai N, Kreps S (1999) Detection of choroidal calcium by computed tomography scan quantitative computerized tomography. Ophthalmology 106(9):1841\u20131846","journal-title":"Ophthalmology"},{"key":"1528_CR12","unstructured":"Maria Pefkianaki KS, Shields CL (2016) Enlargement of choroidal osteoma in a child. Retina Today 30\u201341"},{"issue":"1","key":"1528_CR13","doi-asserted-by":"publisher","first-page":"e35","DOI":"10.1016\/j.jfo.2017.03.025","volume":"41","author":"M Bouladi","year":"2018","unstructured":"Bouladi M et al (2018) Four-year SD-OCT follow-up of a treated bilateral choroidal osteoma complicated by choroidal neovascularisation. Journal Fran\u00e7ais d\u2019Ophtalmologie 41(1):e35\u2013e38","journal-title":"Journal Fran\u00e7ais d\u2019Ophtalmologie"},{"key":"1528_CR14","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1097\/IAE.0000000000000288","volume":"34","author":"L Carol","year":"2014","unstructured":"Carol L, Shields MP, Ferenczy SR, Shields JA (2014) Enhanced depth imaging optical coherence tomography of intraocular tumors. Retina 34:1495\u20131521","journal-title":"Retina"},{"key":"1528_CR15","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1097\/IAE.0000000000000376","volume":"35","author":"CL Shields","year":"2015","unstructured":"Shields CL, Arepalli S, Atalay HT, Ferenczy SR, Fulco E, Shields JA (2015) Choroidal osteoma shows bone lamella and vascular channels on enhanced depth imaging optical coherence tomography in 15 eyes. RETINA 35:750\u2013757","journal-title":"RETINA"},{"key":"1528_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1167\/iovs.14-14287","volume":"56","author":"S Li","year":"2015","unstructured":"Li S, Li H, Bai Y, Cheng Y, Tian J, Wang S, Sun Y, Wang K, Wang F, Zhang Q, Meng Q, Qi Y, Yu Y, Li X (2015) Retina in vivo study of retinal transmission function in different sections of the choroidal structure using multispectral imaging. Investig Ophthalmol Vis Sci 56:1\u201312","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"2","key":"1528_CR17","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1111\/j.1444-0938.2006.00012.x","volume":"89","author":"J Chen","year":"2006","unstructured":"Chen J, Lee L, Gass JDM (2006) Choroidal osteoma: evidence of progression and decalcification over 20 years. Clin Exp Optom 89(2):90\u201394","journal-title":"Clin Exp Optom"},{"key":"1528_CR18","doi-asserted-by":"crossref","unstructured":"Behera M, Das M (2015) A case of choroidal osteoma in a 10-year-old child. Int Med Case Rep J","DOI":"10.2147\/IMCRJ.S92693"},{"issue":"10","key":"1528_CR19","doi-asserted-by":"publisher","first-page":"e185998","DOI":"10.1001\/jamaophthalmol.2018.5998","volume":"137","author":"ME Aronow","year":"2019","unstructured":"Aronow ME, Crowell EL, Reddy AK (2019) Bilateral choroidal osteoma of childhood. JAMA Ophthalmol 137(10):e185998","journal-title":"JAMA Ophthalmol"},{"key":"1528_CR20","first-page":"1","volume":"29","author":"CFLD Antonio","year":"2019","unstructured":"Antonio CFLD, Alessio MOGMRMRANG (2019) Choroidal neovascularization due to choroidal osteoma treated with anti\u2013vascular endothelial growth factor therapy: an optical coherence tomography angiography study. Eur J Ophthalmol 29:1\u20135","journal-title":"Eur J Ophthalmol"},{"issue":"1","key":"1528_CR21","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.oret.2017.05.011","volume":"2","author":"P Sagar","year":"2018","unstructured":"Sagar P et al (2018) OCT angiography characteristics of choroidal osteoma. Ophthalmol Retina 2(1):77\u201379","journal-title":"Ophthalmol Retina"},{"key":"1528_CR22","doi-asserted-by":"crossref","first-page":"251584142092274","DOI":"10.1177\/2515841420922740","volume":"12","author":"SV Azad","year":"2020","unstructured":"Azad SV et al (2020) In vivo optical biopsy of choroidal osteoma: a swept source optical coherence tomography-based tumor characterization. Ther Adv Ophthalmol 12:2515841420922740","journal-title":"Ther Adv Ophthalmol"},{"key":"1528_CR23","doi-asserted-by":"crossref","unstructured":"Gelb K et al (2016) Retinal multispectral imaging of \u2018sub-clinical\u2019 capillary micro-aneurysms in non-diabetics correlates with insulin resistance. Diabesity 2(3)","DOI":"10.15562\/diabesity.2016.27"},{"issue":"5","key":"1528_CR24","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1002\/lsm.22619","volume":"49","author":"X Zhu","year":"2017","unstructured":"Zhu X et al (2017) Sensitivity and specificity of multispectral imaging in detecting central serous chorioretinopathy. Lasers Surg Med 49(5):498\u2013505","journal-title":"Lasers Surg Med"},{"issue":"2","key":"1528_CR25","doi-asserted-by":"publisher","first-page":"257","DOI":"10.3928\/23258160-20150213-09","volume":"46","author":"CE Pang","year":"2015","unstructured":"Pang CE et al (2015) New insights into stargardt disease with multimodal imaging. Ophthalmic Surg Lasers Imaging Retina 46(2):257\u2013261","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"issue":"4","key":"1528_CR26","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1111\/aos.13606","volume":"96","author":"G Huang","year":"2018","unstructured":"Huang G et al (2018) Multispectral image analysis in Vogt-Koyanagi-Harada disease. Acta Ophthalmol 96(4):411\u2013419","journal-title":"Acta Ophthalmol"},{"issue":"7","key":"1528_CR27","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1002\/lsm.22392","volume":"47","author":"Y Xu","year":"2015","unstructured":"Xu Y et al (2015) A light-emitting diode (LED)-based multispectral imaging system in evaluating retinal vein occlusion. Lasers Surg Med 47(7):549\u2013558","journal-title":"Lasers Surg Med"},{"issue":"2","key":"1528_CR28","doi-asserted-by":"publisher","first-page":"134","DOI":"10.3928\/23258160-20160126-06","volume":"47","author":"PU Dugel","year":"2016","unstructured":"Dugel PU, Zimmer CN (2016) Imaging of melanin disruption in age-related macular degeneration using multispectral imaging. Ophthalmic Surg Lasers Imaging Retina 47(2):134\u2013141","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"1528_CR29","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1097\/OPX.0000000000000642","volume":"92","author":"J Zhang","year":"2015","unstructured":"Zhang J, Yu Z, Liu L (2015) Multimodality imaging in diagnosing polypoidal choroidal vasculopathy. Optom Vis Sci 92:1\u20136","journal-title":"Optom Vis Sci"},{"issue":"12","key":"1528_CR30","doi-asserted-by":"publisher","first-page":"e249","DOI":"10.3928\/23258160-20181203-15","volume":"49","author":"J Zhang","year":"2018","unstructured":"Zhang J et al (2018) Characteristics of polypoidal choroidal vasculopathy evaluated by multispectral imaging. Ophthalmic Surg Lasers Imaging Retina 49(12):e249\u2013e255","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"1528_CR31","unstructured":"Zhang J, CY-B, Yu Z-K, Liu L (2018) Multispectral imaging in detecting early retinal pigment epithelial atrophy. Int J Ophthalmol"},{"issue":"20","key":"1528_CR32","doi-asserted-by":"publisher","first-page":"e15655","DOI":"10.1097\/MD.0000000000015655","volume":"98","author":"L Feng","year":"2019","unstructured":"Feng L et al (2019) Retinal and choroidal abnormalities identified by multispectral imaging in patients with uveitis: three case reports. Medicine (Baltimore) 98(20):e15655","journal-title":"Medicine (Baltimore)"},{"issue":"7","key":"1528_CR33","doi-asserted-by":"publisher","first-page":"572","DOI":"10.3928\/23258160-20170630-08","volume":"48","author":"NY Gan","year":"2017","unstructured":"Gan NY, Zimmer C, Lam W-C (2017) Multi-spectral imaging of circumscribed choroidal hemangioma introduction. Ophthalmic Surg Lasers Imaging Retina 48(7):572\u2013575","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"1528_CR34","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1097\/ICB.0b013e31828523a8","volume":"7","author":"R Gallego-Pinazo","year":"2013","unstructured":"Gallego-Pinazo R, Sherman J, Yannuzzi LA, Freund KB (2013) Choroidal lesions in neurofibromatosis detected by multispectral imaging. Retinal Cases Brief Rep 7:176\u2013178","journal-title":"Retinal Cases Brief Rep"},{"key":"1528_CR35","doi-asserted-by":"crossref","unstructured":"Sisk RA, CDR, Petersen MR, Foster RE, Miller DM, Murray TG, Augsburger JJ (2013) Fundus autofluorescence findings of choroidal osteoma. Retina 33:97\u2013104","DOI":"10.1097\/IAE.0b013e31825c1cde"},{"key":"1528_CR36","doi-asserted-by":"publisher","first-page":"1061","DOI":"10.1364\/AO.28.001061","volume":"28","author":"FC Delori","year":"1989","unstructured":"Delori FC, Pflibsen KP (1989) Spectral reflectance of the human ocular fundus. Appl Opt 28:1061\u20131077","journal-title":"Appl Opt"},{"issue":"1","key":"1528_CR37","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1097\/IAE.0b013e31825c1cde","volume":"33","author":"RA Sisk","year":"2013","unstructured":"Sisk RA et al (2013) Fundus autofluorescence findings of choroidal osteoma. Retina 33(1):97\u2013104","journal-title":"Retina"},{"key":"1528_CR38","doi-asserted-by":"crossref","unstructured":"Venkatesh R et al (2018) Multicolor imaging in choroidal osteomas. Int J Retina Vitreous 4(1)","DOI":"10.1186\/s40942-018-0150-y"},{"key":"1528_CR39","doi-asserted-by":"crossref","unstructured":"Rajabian F et al (2019) Focal choroidal excavation and pitchfork sign in choroidal neovascularisation associated with choroidal osteoma. Eur J Ophthalmol 1120672119892802","DOI":"10.1177\/1120672119892802"},{"issue":"5","key":"1528_CR40","doi-asserted-by":"publisher","first-page":"242","DOI":"10.1016\/j.oftale.2018.03.008","volume":"93","author":"R Clemente-Tom\u00e1s","year":"2018","unstructured":"Clemente-Tom\u00e1s R et al (2018) Choroidal osteoma with choroidal excavation and associated neovascular membrane: an OCT-angiography study. Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition) 93(5):242\u2013245","journal-title":"Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition)"},{"key":"1528_CR41","doi-asserted-by":"crossref","unstructured":"Rajesh B et al (2015) Real-time in vivo micromorphology and histopathology of choroidal osteoma using enhanced depth imaging. Indian J Ophthalmol 63(5)","DOI":"10.4103\/0301-4738.159887"},{"issue":"1005","key":"1528_CR42","doi-asserted-by":"publisher","first-page":"775","DOI":"10.1259\/bjr\/32022497","volume":"84","author":"AA Razek","year":"2011","unstructured":"Razek AA, Elkhamary S (2011) MRI of retinoblastoma. Br J Radiol 84(1005):775\u2013784","journal-title":"Br J Radiol"},{"issue":"5","key":"1528_CR43","doi-asserted-by":"publisher","first-page":"944","DOI":"10.3174\/ajnr.A2892","volume":"33","author":"AA Abdel Razek","year":"2012","unstructured":"Abdel Razek AA et al (2012) Correlation of apparent diffusion coefficient at 3T with prognostic parameters of retinoblastoma. AJNR Am J Neuroradiol 33(5):944\u2013948","journal-title":"AJNR Am J Neuroradiol"},{"issue":"1","key":"1528_CR44","doi-asserted-by":"publisher","first-page":"170","DOI":"10.3174\/ajnr.A3619","volume":"35","author":"AR Sepahdari","year":"2014","unstructured":"Sepahdari AR et al (2014) Diffusion-weighted imaging of orbital masses: multi-institutional data support a 2-ADC threshold model to categorize lesions as benign, malignant, or indeterminate. AJNR Am J Neuroradiol 35(1):170\u2013175","journal-title":"AJNR Am J Neuroradiol"}],"updated-by":[{"DOI":"10.1007\/s10792-020-01678-w","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2021,1,16]],"date-time":"2021-01-16T00:00:00Z","timestamp":1610755200000}}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01528-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-020-01528-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01528-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T19:51:18Z","timestamp":1627588278000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-020-01528-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,30]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["1528"],"URL":"https:\/\/doi.org\/10.1007\/s10792-020-01528-9","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"value":"0165-5701","type":"print"},{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,30]]},"assertion":[{"value":"21 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 July 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 January 2021","order":4,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":5,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"A Correction to this paper has been published:","order":6,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"https:\/\/doi.org\/10.1007\/s10792-020-01678-w","URL":"https:\/\/doi.org\/10.1007\/s10792-020-01678-w","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors have no conflict of interest to declare.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}