{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T17:53:22Z","timestamp":1759341202729,"version":"3.37.3"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T00:00:00Z","timestamp":1603152000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1007\/s10792-020-01615-x","type":"journal-article","created":{"date-parts":[[2020,10,20]],"date-time":"2020-10-20T06:02:52Z","timestamp":1603173772000},"page":"605-611","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Intraocular pressure-lowering effects of ripasudil, a rho-kinase inhibitor, and selective laser trabeculoplasty as adjuvant therapy in patients with uncontrolled glaucoma"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4019-2740","authenticated-orcid":false,"given":"Koichi","family":"Ono","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fumika","family":"Sakemi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Marumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,10,20]]},"reference":[{"issue":"6","key":"1615_CR1","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1097\/APO.0000000000000264","volume":"8","author":"HR Taylor","year":"2019","unstructured":"Taylor HR (2019) Global blindness: the progress we are making and still need to make. Asia Pac J Ophthalmol (Phila) 8(6):424\u2013428","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"issue":"1","key":"1615_CR2","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1007\/s10384-018-0623-4","volume":"63","author":"Y Morizane","year":"2019","unstructured":"Morizane Y, Morimoto N, Fujiwara A, Kawasaki R, Yamashita H, Ogura Y, Shiraga F (2019) Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals. Jpn J Ophthalmol 63(1):26\u201333","journal-title":"Jpn J Ophthalmol"},{"issue":"9","key":"1615_CR3","first-page":"1641","volume":"111","author":"A Iwase","year":"2004","unstructured":"Iwase A, Suzuki Y, Araie M, Yamamoto T, Abe H, Shirato S, Kuwayama Y, Mishima HK, Shimizu H, Tomita G, Inoue Y, Kitazawa Y, Tajimi Study Group, Japan Glaucoma Society (2004) The prevalence of primary open-angle glaucoma in Japanese: the Tajimi Study. Ophthalmology 111(9):1641\u20131648","journal-title":"Ophthalmology"},{"issue":"10","key":"1615_CR4","doi-asserted-by":"publisher","first-page":"1661","DOI":"10.1016\/j.ophtha.2005.05.012","volume":"112","author":"T Yamamoto","year":"2005","unstructured":"Yamamoto T, Iwase A, Araie M, Suzuki Y, Abe H, Shirato S, Kuwayama Y, Mishima HK, Shimizu H, Tomita G, Inoue Y, Kitazawa Y, Tajimi Study Group, Japan Glaucoma Society (2005) The Tajimi Study report 2: prevalence of primary angle closure and secondary glaucoma in a Japanese population. Ophthalmology 112(10):1661\u20131669","journal-title":"Ophthalmology"},{"issue":"4","key":"1615_CR5","doi-asserted-by":"publisher","first-page":"731","DOI":"10.1016\/j.ajo.2013.05.016","volume":"156","author":"H Tanihara","year":"2013","unstructured":"Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Araie M, K-115 Clinical Study Group (2013) Phase 2 randomized clinical study of a Rho kinase inhibitor, K-115, in primary open-angle glaucoma and ocular hypertension. Am J Ophthalmol 156(4):731\u2013736","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"1615_CR6","doi-asserted-by":"publisher","first-page":"e254","DOI":"10.1111\/aos.12599","volume":"93","author":"H Tanihara","year":"2015","unstructured":"Tanihara H, Inoue T, Yamamoto T, Kuwayama Y, Abe H, Suganami H, Araie M, K-115 Clinical Study Group (2015) Intra-ocular pressure-lowering effects of a Rho kinase inhibitor, ripasudil (K-115), over 24 hours in primary open-angle glaucoma and ocular hypertension: a randomized, open-label, crossover study. Acta Ophthalmol 93(4):e254\u2013e260","journal-title":"Acta Ophthalmol"},{"issue":"2","key":"1615_CR7","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s10384-018-0566-9","volume":"62","author":"M Honjo","year":"2018","unstructured":"Honjo M, Tanihara H (2018) Impact of the clinical use of ROCK inhibitor on the pathogenesis and treatment of glaucoma. Jpn J Ophthalmol 62(2):109\u2013126","journal-title":"Jpn J Ophthalmol"},{"key":"1615_CR8","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/s12325-018-0863-1","volume":"36","author":"H Tanihara","year":"2019","unstructured":"Tanihara H, Kakuda T, Sano T, Kanno T, Imada R, Shingaki W, Gunji R (2019) Safety and efficacy of Ripasudil in Japanese Patients with glaucoma or ocular hypertension: 3-month interim analysis of ROCK-J a post-marketing surveillance study. Adv Ther 36:333\u2013343","journal-title":"Adv Ther"},{"key":"1615_CR9","doi-asserted-by":"publisher","first-page":"19640","DOI":"10.1038\/srep19640","volume":"6","author":"Y Kaneko","year":"2016","unstructured":"Kaneko Y, Ohta M, Inoue T, Mizuno K, Isobe T, Tanabe S, Tanihara H (2016) Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm\u2019s canal endothelial cells. Sci Rep 6:19640","journal-title":"Sci Rep"},{"issue":"4","key":"1615_CR10","doi-asserted-by":"publisher","first-page":"180","DOI":"10.5694\/mja2.50020","volume":"210","author":"J Lusthaus","year":"2019","unstructured":"Lusthaus J, Goldberg I (2019) Current management of glaucoma. Med J Aust 210(4):180\u2013187","journal-title":"Med J Aust"},{"key":"1615_CR11","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1136\/bjo.2008.148510","volume":"93","author":"M Nagar","year":"2009","unstructured":"Nagar M, Luhishi E, Shah N (2009) Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty. Br J Ophthalmol 93:497\u2013501","journal-title":"Br J Ophthalmol"},{"issue":"7","key":"1615_CR12","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1097\/IJG.0b013e318218287f","volume":"21","author":"LJ Katz","year":"2012","unstructured":"Katz LJ, Steinmann WC, Kabir A, Molineaux J, Wizov SS, Marcellino G, SLT\/Med Study Group (2012) Selective laser trabeculoplasty versus medical therapy as initial treatment of glaucoma: a prospective, randomized trial. J Glaucoma 21(7):460\u2013468","journal-title":"J Glaucoma"},{"key":"1615_CR13","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1111\/j.1442-9071.2004.00839.x","volume":"32","author":"JS Lai","year":"2004","unstructured":"Lai JS, Chua JK, Tham CC, Lam DS (2004) Five-year follow up of selective laser trabeculoplasty in Chinese eyes. Clin Experiment Ophthalmol 32:368\u2013372","journal-title":"Clin Experiment Ophthalmol"},{"key":"1615_CR14","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1038\/eye.2013.267","volume":"28","author":"C McAlinden","year":"2014","unstructured":"McAlinden C (2014) Selective laser trabeculoplasty (SLT) vs other treatment modalities for glaucoma: systematic review. Eye 28:249\u2013258","journal-title":"Eye"},{"issue":"15","key":"1615_CR15","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1186\/s12886-015-0091-2","volume":"19","author":"X Li","year":"2015","unstructured":"Li X, Wang W, Zhang X (2015) Meta-analysis of selective laser trabeculoplasty versus topical medication in the treatment of open-angle glaucoma. BMC Ophthalmol 19(15):107","journal-title":"BMC Ophthalmol"},{"issue":"1","key":"1615_CR16","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1186\/s12886-016-0385-z","volume":"16","author":"M Chun","year":"2016","unstructured":"Chun M, Gracitelli CP, Lopes FS, Biteli LG, Ushida M, Prata TS (2016) Selective laser trabeculoplasty for early glaucoma: analysis of success predictors and adjusted laser outcomes based on the untreated fellow eye. BMC Ophthalmol 16(1):206","journal-title":"BMC Ophthalmol"},{"issue":"6","key":"1615_CR17","doi-asserted-by":"publisher","first-page":"535","DOI":"10.1007\/s40261-017-0509-0","volume":"37","author":"R Matsumura","year":"2017","unstructured":"Matsumura R, Inoue T, Matsumura A, Tanihara H (2017) Efficacy of ripasudil as a second-line medication in addition to a prostaglandin analog in patients with exfoliation glaucoma: a pilot study. Clin Drug Investig 37(6):535\u2013539","journal-title":"Clin Drug Investig"},{"issue":"10","key":"1615_CR18","doi-asserted-by":"publisher","first-page":"2009","DOI":"10.1007\/s00417-017-3727-5","volume":"255","author":"H Inazaki","year":"2017","unstructured":"Inazaki H, Kobayashi S, Anzai Y, Satoh H, Sato S, Inoue M, Yamane S, Kadonosono K (2017) One-year efficacy of adjunctive use of Ripasudil, a rho-kinase inhibitor, in patients with glaucoma inadequately controlled with maximum medical therapy. Graefes Arch Clin Exp Ophthalmol 255(10):2009\u20132015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"2","key":"1615_CR19","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1007\/s12325-018-0863-1","volume":"36","author":"H Tanihara","year":"2019","unstructured":"Tanihara H, Kakuda T, Sano T, Kanno T, Imada R, Shingaki W, Gunji R (2019) Safety and efficacy of ripasudil in japanese patients with glaucoma or ocular hypertension: 3-month interim analysis of ROCK-J, a post-marketing surveillance study. Adv Ther 36(2):333\u2013343","journal-title":"Adv Ther"},{"issue":"4","key":"1615_CR20","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1001\/jamaophthalmol.2013.7651","volume":"132","author":"DA Greninger","year":"2014","unstructured":"Greninger DA, Lowry EA, Porco TC, Naseri A, Stamper RL, Han Y (2014) Resident-performed selective laser trabeculoplasty in open angle glaucoma patients. JAMA Ophthalmol 132(4):403\u2013408","journal-title":"JAMA Ophthalmol"},{"key":"1615_CR21","first-page":"833","volume":"9","author":"KE Leahy","year":"2015","unstructured":"Leahy KE, White AJ (2015) Selective laser trabeculoplasty: current perspectives. Clin Ophthalmol 9:833\u2013841","journal-title":"Clin Ophthalmol"},{"key":"1615_CR22","doi-asserted-by":"publisher","first-page":"957","DOI":"10.1185\/03007991003659012","volume":"26","author":"SR Hahn","year":"2010","unstructured":"Hahn SR, Kotak S, Tan J, Kim E (2010) Physicians\u2019 treatment decisions, patient persistence, and interruptions in the continuous use of prostaglandin therapy in glaucoma. Curr Med Res Opin 26:957\u2013963","journal-title":"Curr Med Res Opin"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01615-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-020-01615-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-020-01615-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,20]],"date-time":"2021-10-20T10:20:44Z","timestamp":1634725244000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-020-01615-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,20]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["1615"],"URL":"https:\/\/doi.org\/10.1007\/s10792-020-01615-x","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"type":"print","value":"0165-5701"},{"type":"electronic","value":"1573-2630"}],"subject":[],"published":{"date-parts":[[2020,10,20]]},"assertion":[{"value":"10 June 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 October 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 October 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors (KO, FS, and TM) declare that we have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}