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Therefore, we conducted this pilot study to assess whether a nonmydriatic ultra-wide-field (UWF) scanning laser ophthalmoscope (SLO) is suitable for a simple, rapid screening procedure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The population of this cross-sectional study was randomly recruited from a cohort of hospital-based patients in an urban geriatric hospital. Ophthalmologic evaluation was performed on 201 eyes from 101 participants through nonmydriatic UWF-SLO (Optos Daytona) and assessed for suspicious lesions and other relevant ocular findings. All images were evaluated by two independent examiners. Individuals who presented lesions with a morphological appearance suggestive of OT underwent fundoscopy and serological analysis of<jats:italic>Toxoplasma gondii<\/jats:italic>-specific antibodies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the study group was 76\u00a0years, and 63 (62%) were female. Despite many health restrictions, the SLO examination was carried out easily in this geriatric population. Three participants presented findings by SLO suspicious for<jats:italic>T. gondii<\/jats:italic>-related injury. Further clinical examination and serological investigation confirmed the diagnosis, with funduscopic evaluation and positive<jats:italic>T. gondii<\/jats:italic>ELISA testing. In addition, a high rate of arterial hypertension and dyslipidemias within the cohort led to a high incidence of vascular changes and age-related fundus findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our study, we confirm that UWF-SLO technology is helpful in the rapid detection of peripheral retinal injuries in elderly patients such as OT and may be used as a routine screening tool.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s10792-020-01683-z","type":"journal-article","created":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T11:17:36Z","timestamp":1615893456000},"page":"1573-1584","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2147-3571","authenticated-orcid":false,"given":"Pablo Eduardo","family":"Logro\u00f1o Wiese","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Seeber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne-Sophie","family":"Endres","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Brockmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Uwe","family":"Pleyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,3,16]]},"reference":[{"key":"1683_CR1","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1159\/000363141","volume":"52","author":"U Pleyer","year":"2014","unstructured":"Pleyer U, Schl\u00fcter D, M\u00e4nz M (2014) Ocular toxoplasmosis: recent aspects of pathophysiology and clinical implications. 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UP and FS conceived and designed the study. PELW performed the scanning. PELW, CB and UP analyzed the data. FS, UP and ASE contributed reagents\/materials\/tools. PELW, UP, FS and ASE wrote the manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures were performed in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The study protocol and study documents were approved by the local ethics committee (EA4\/034\/16).","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}