{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T07:33:50Z","timestamp":1740123230761,"version":"3.37.3"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T00:00:00Z","timestamp":1625356800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T00:00:00Z","timestamp":1625356800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2021,8]]},"DOI":"10.1007\/s10792-021-01845-7","type":"journal-article","created":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T07:02:26Z","timestamp":1625382146000},"page":"2861-2868","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicodemographic pattern and treatment outcome of Behcet\u2019s disease cases presenting in a tertiary eye center of Nepal"],"prefix":"10.1007","volume":"41","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7970-4443","authenticated-orcid":false,"given":"Anu","family":"Manandhar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Buddhi Prasad","family":"Paudyal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,7,4]]},"reference":[{"issue":"12","key":"1845_CR1","doi-asserted-by":"publisher","first-page":"1579","DOI":"10.1136\/bjo.2007.123554","volume":"91","author":"N Kitaichi","year":"2007","unstructured":"Kitaichi N, Miyazaki A, Stanford MR, Chams H, Iwata D, Ohno S (2007) Ocular features of Behcet\u2019s disease: international collaborative study. Br J Ophthalmol 91(12):1579\u20131582","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"1845_CR2","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1007\/s10792-008-9273-8","volume":"29","author":"N Sachdev","year":"2009","unstructured":"Sachdev N, Kapali N, Singh R, Gupta V, Gupta A (2009) Spectrum of Behcet\u2019s disease in Indian population. Int Ophthalmol 29(6):495\u2013501","journal-title":"Int Ophthalmol"},{"issue":"3","key":"1845_CR3","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1016\/j.ajo.2004.03.022","volume":"138","author":"I Tugal-Tutkun","year":"2004","unstructured":"Tugal-Tutkun I, Onal S, Altan-Yaycioglu R, Altunbas H, Urgancioglu M (2004) Uveitis in Behcet disease: an analysis of 880 patients. Am J Ophthalmol 138(3):373\u2013380","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"1845_CR4","doi-asserted-by":"publisher","first-page":"615","DOI":"10.3346\/jkms.2001.16.5.615","volume":"16","author":"D Bang","year":"2001","unstructured":"Bang D, Lee JH, Lee ES, Lee S, Choi JS, Kim YK, Cho BK, Koh JK, Won YH, Kim NI, Park SD, Ahn HJ, Lee YW, Wang HY, Lee WW, Eun HC, Song ES, Lee SW, Lee CW, Lee CJ, Park JH, Song YW, Kim ST, Kim CY, Park JK, Kwon KS (2001) Epidemiologic and clinical survey of Behcet\u2019s disease in Korea: the first multicenter study. J Korean Med Sci 16(5):615\u2013618","journal-title":"J Korean Med Sci"},{"issue":"1","key":"1845_CR5","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1002\/art.22500","volume":"57","author":"C Salvarani","year":"2007","unstructured":"Salvarani C, Pipitone N, Catanoso MG, Cimino L, Tumiati B, Macchioni P, Bajocchi G, Olivieri I, Boiardi L (2007) Epidemiology and clinical course of Beh\u00e7et\u2019s disease in the Reggio Emilia area of Northern Italy: a seventeen-year population-based study. Arth Rheum 57(1):171\u2013178","journal-title":"Arth Rheum"},{"key":"1845_CR6","first-page":"663","volume-title":"Ocular infection and immunity","author":"M Mochizuki","year":"1996","unstructured":"Mochizuki M, Akduman L, Nussenblatt RB (1996) Behcet\u2019s disease. In: Pepose JS, Holland GN, Wilhelmus KR (eds) Ocular infection and immunity. Mosby, St Louis, pp 663\u2013675"},{"issue":"10","key":"1845_CR7","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1046\/j.1365-4362.2003.01893.x","volume":"42","author":"G Azizlerli","year":"2003","unstructured":"Azizlerli G, K\u00f6se AA, Sarica R, G\u00fcl A, Tutkun IT, Kula\u00e7 M, Tun\u00e7 R, Urgancio\u011flu M, Di\u015f\u00e7i R (2003) Prevalence of Behcet\u2019s disease in Istanbul. Turkey Int J Dermatol 42(10):803\u2013806","journal-title":"Turkey Int J Dermatol"},{"issue":"22","key":"1845_CR8","first-page":"250","volume":"10","author":"B Paudyal","year":"2012","unstructured":"Paudyal B, Gyawalee M, Manandhar A, Sigdel K (2012) Behcet\u2019s disease: an account of three cases. J Nepal Health Res Counc 10(22):250\u2013253","journal-title":"J Nepal Health Res Counc"},{"key":"1845_CR9","doi-asserted-by":"publisher","first-page":"S54","DOI":"10.3109\/09273948.2016.1161804","volume":"25","author":"A Manandhar","year":"2017","unstructured":"Manandhar A (2017) Patterns of Uveitis and Scleritis in Nepal: a tertiary referral center study. Ocul Immunol Inflam 25:S54\u2013S62","journal-title":"Ocul Immunol Inflam"},{"issue":"19","key":"1845_CR10","first-page":"35","volume":"7","author":"JB Shrestha","year":"2017","unstructured":"Shrestha JB, Shah DN (2017) Systemic association of Uveitis in Nepalese population. J Chitwan Med Coll 7(19):35\u201340","journal-title":"J Chitwan Med Coll"},{"key":"1845_CR11","doi-asserted-by":"crossref","unstructured":"(2014) The International Criteria for Beh\u00e7et's Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venereol .28(3):338\u201347","DOI":"10.1111\/jdv.12107"},{"issue":"3","key":"1845_CR12","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.ajo.2005.03.057","volume":"140","author":"DA Jabs","year":"2005","unstructured":"Jabs DA, Nussenblatt RB, Rosenbaum JT (2005) Standardization of Uveitis nomenclature (SUN) working group. Am J Ophthalmol 140(3):509\u2013516","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"1845_CR13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/0974-9233.58425","volume":"16","author":"I Tugal-Tutkun","year":"2009","unstructured":"Tugal-Tutkun I (2009) Beh\u00e7et\u2019s Uveitis. Middle East Afr J Ophthalmol 16(4):219\u2013224","journal-title":"Middle East Afr J Ophthalmol"},{"issue":"2","key":"1845_CR14","doi-asserted-by":"publisher","first-page":"199","DOI":"10.4103\/0378-6323.107636","volume":"79","author":"A Singal","year":"2013","unstructured":"Singal A, Chhabra N, Pandhi D, Rohatgi J (2013) Behcet\u2019s disease in India: a dermatological perspective. Indian J Dermatol Venereol Leprol 79(2):199\u2013204","journal-title":"Indian J Dermatol Venereol Leprol"},{"issue":"4","key":"1845_CR15","doi-asserted-by":"publisher","first-page":"239","DOI":"10.5152\/eurjrheum.2017.17112","volume":"4","author":"NC Kilian","year":"2017","unstructured":"Kilian NC, Sawalha AH (2017) Behcet\u2019s disease in the United States: a single center descriptive and comparative study. Eur J Rheumatol 4(4):239\u2013244","journal-title":"Eur J Rheumatol"},{"key":"1845_CR16","doi-asserted-by":"publisher","first-page":"1813","DOI":"10.1001\/archopht.1977.04450100115015","volume":"95","author":"DM Colvard","year":"1977","unstructured":"Colvard DM, Robertson DM, O\u2019Duffy JD (1977) The ocular manifestations of Behcet\u2019s disease. Arch Ophthalmol 95:1813\u20131817","journal-title":"Arch Ophthalmol"},{"issue":"9","key":"1845_CR17","first-page":"1191","volume":"30","author":"LY Wang","year":"2009","unstructured":"Wang LY, Zhao DB, Gu J, Dai SM (2009) Clinical features of Behcets disease in China. Rheumatol 30(9):1191\u20131196","journal-title":"Rheumatol"},{"key":"1845_CR18","first-page":"2","volume":"37","author":"L Abasi","year":"2017","unstructured":"Abasi L, Al-Rabadi HF, Alrabadi ES, Nsour HF (2017) Behcet\u2019s disease: a study done at King Jussein Medical Center. Amman-Jordan Pak Oral Dental J 37:2","journal-title":"Amman-Jordan Pak Oral Dental J"},{"issue":"2","key":"1845_CR19","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.ophtha.2007.04.056","volume":"115","author":"P Yang","year":"2008","unstructured":"Yang P, Fang W, Meng Q, Ren Y, Xing L, Kijlstra A (2008) Clinical features of Chinese patients with Beh\u00e7et\u2019s disease. Ophthalmology 115(2):312\u2013318","journal-title":"Ophthalmology"},{"key":"1845_CR20","doi-asserted-by":"publisher","first-page":"140","DOI":"10.1136\/bjo.86.2.140","volume":"86","author":"T Matsuo","year":"2002","unstructured":"Matsuo T, Itami M, Nakagawa H (2002) The incidence and pathology of conjunctival ulceration in Behcet\u2019s syndrome. Br J Ophthalmol 86:140\u2013143","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"1845_CR21","doi-asserted-by":"publisher","first-page":"240","DOI":"10.4103\/0301-4738.81048","volume":"59","author":"A Al-Mujaini","year":"2011","unstructured":"Al-Mujaini A, Wali KU (2011) Frosted branch angiitis, neuroretinitis as initial ocular manifestation in ocular Behcet\u2019s. Indian J Ophthalmol 59(3):240\u2013241","journal-title":"Indian J Ophthalmol"},{"key":"1845_CR22","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1177\/112067210201200514","volume":"12","author":"PC Ozdal","year":"2002","unstructured":"Ozdal PC, Ortac S, Taskintuna I, Firat E (2002) Posterior segment involvement in ocular Behcet\u2019s disease. Eur J Ophthalmol 12:424\u2013431","journal-title":"Eur J Ophthalmol"},{"key":"1845_CR23","doi-asserted-by":"crossref","unstructured":"Atmaca LS (1989) Fundus changes associated with Behcet\u2019s disease. Graefes Arch Clin Exp Ophthalmol 227:340\u2013344. 10. International Study Group for Behcet\u2019s Disease. Evaluatio","DOI":"10.1007\/BF02169409"},{"issue":"5","key":"1845_CR24","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1002\/art.24423","volume":"61","author":"KT Calamia","year":"2009","unstructured":"Calamia KT, Wilson FC, Icen M, Crowson SC (2009) Epidemiology and clinical characteristics of Beh\u00e7et\u2019s disease in the US: a population-based study. Arth Rheumatol 61(5):600\u2013604","journal-title":"Arth Rheumatol"},{"issue":"2","key":"1845_CR25","doi-asserted-by":"publisher","first-page":"304","DOI":"10.1093\/rheumatology\/kes249","volume":"52","author":"A Mohammad","year":"2013","unstructured":"Mohammad A, Mandl T, Sturfelt G, Segelmark M (2013) Incidence, prevalence and clinical characteristics of Behcet\u2019s disease in southern Sweden. Rheumatology (Oxford) 52(2):304\u2013310","journal-title":"Rheumatology (Oxford)"},{"issue":"7","key":"1845_CR26","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/j.jfma.2018.03.005","volume":"117","author":"Y HsuehWu","year":"2018","unstructured":"HsuehWu Y, Chang JY, Wang Y, Wu Y, Chen H, Sun A (2018) Hemoglobin, iron, vitamin B12, and folic acid deficiencies and hyperhomocysteinemia in Behcet\u2019s disease patients with atrophic glossitis. J Formosan Med Assoc 117(7):559\u2013565","journal-title":"J Formosan Med Assoc"},{"issue":"4","key":"1845_CR27","first-page":"208","volume":"13","author":"C Yamamori","year":"1994","unstructured":"Yamamori C, Ishino H, Inagaki T, Seno H, Iijima M, Torii I, Harada T, Morikawa S (1994) Neuro-Beh\u00e7et disease with demyelination and gliosis of the frontal white matter. Clin Neuropathol 13(4):208\u2013215","journal-title":"Clin Neuropathol"},{"key":"1845_CR28","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1056\/NEJM199002013220501","volume":"322","author":"H Yazici","year":"1990","unstructured":"Yazici H, Pazarli H, Barnes CG, T\u00fcz\u00fcn Y, Ozyazgan Y, Silman A, Serdaro\u011flu S, O\u011fuz V, Yurdakul S, Lovatt GE et al (1990) A controlled trial of azathioprine in Beh\u00e7et\u2019s syndrome. N Engl J Med 322:281\u2013285","journal-title":"N Engl J Med"},{"key":"1845_CR29","doi-asserted-by":"publisher","first-page":"1733","DOI":"10.1002\/acr.20308","volume":"62","author":"D Saadoun","year":"2010","unstructured":"Saadoun D, Wechsler B, Terrada C et al (2010) Azathioprine in severe uveitis of Behcet\u2019s disease. Arthritis Care Res (Hoboken) 62:1733\u20131738","journal-title":"Arthritis Care Res (Hoboken)"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-021-01845-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-021-01845-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-021-01845-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T08:20:02Z","timestamp":1725351602000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-021-01845-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,4]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["1845"],"URL":"https:\/\/doi.org\/10.1007\/s10792-021-01845-7","relation":{},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"type":"print","value":"0165-5701"},{"type":"electronic","value":"1573-2630"}],"subject":[],"published":{"date-parts":[[2021,7,4]]},"assertion":[{"value":"30 October 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 April 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no competing interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"NA, since this is a retrospective study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The study is approved for publication by the internal review committee of Tilganga Institute of Ophthalmology.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}