{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T20:47:26Z","timestamp":1772830046230,"version":"3.50.1"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T00:00:00Z","timestamp":1637625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1007\/s10792-021-02125-0","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T02:06:59Z","timestamp":1637633219000},"page":"653-659","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Dynamic thiol disulphide homeostasis in patients with surfer\u2019s eye: a case\u2013control study"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5111-2270","authenticated-orcid":false,"given":"Hanife Tuba","family":"Akcam","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2996-3236","authenticated-orcid":false,"given":"Ozcan","family":"Erel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,11,23]]},"reference":[{"issue":"5","key":"2125_CR1","doi-asserted-by":"publisher","first-page":"76","DOI":"10.17116\/oftalma2017133576-83","volume":"133","author":"SA Malozhen","year":"2017","unstructured":"Malozhen SA, Trufanov SV, Krakhmaleva DA (2017) Pterygium: etiology, pathogenesis, treatment. Vestn Oftalmol 133(5):76\u201383. https:\/\/doi.org\/10.17116\/oftalma2017133576-83","journal-title":"Vestn Oftalmol"},{"issue":"6","key":"2125_CR2","doi-asserted-by":"publisher","first-page":"528","DOI":"10.5935\/0004-2749.20190103","volume":"82","author":"ACV Wanzeler","year":"2019","unstructured":"Wanzeler ACV, Barbosa IAF, Duarte B, Borges D, Barbosa EB, Kamiji D, Huarachi DRG, Melo MB, Alves M (2019) Mechanisms and biomarker candidates in pterygium development. Arq Bras Oftalmol 82(6):528\u2013536. https:\/\/doi.org\/10.5935\/0004-2749.20190103","journal-title":"Arq Bras Oftalmol"},{"issue":"1","key":"2125_CR3","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/s1542-0124(12)70103-9","volume":"6","author":"J Chui","year":"2008","unstructured":"Chui J, Di Girolamo N, Wakefield D, Coroneo MT (2008) The pathogenesis of pterygium: current concepts and their therapeutic implications. Ocul Surf 6(1):24\u201343. https:\/\/doi.org\/10.1016\/s1542-0124(12)70103-9","journal-title":"Ocul Surf"},{"issue":"2","key":"2125_CR4","doi-asserted-by":"publisher","first-page":"246","DOI":"10.3109\/10715762.2015.1110241","volume":"50","author":"MA Comini","year":"2016","unstructured":"Comini MA (2016) Measurement and meaning of cellular thiol:disufhide redox status. Free Radic Res 50(2):246\u2013271. https:\/\/doi.org\/10.3109\/10715762.2015.1110241","journal-title":"Free Radic Res"},{"key":"2125_CR5","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1146\/annurev.nutr.24.012003.132208","volume":"24","author":"SE Moriarty-Craige","year":"2004","unstructured":"Moriarty-Craige SE, Jones DP (2004) Extracellular thiols and thiol\/disulfide redox in metabolism. Annu Rev Nutr 24:481\u2013509. https:\/\/doi.org\/10.1146\/annurev.nutr.24.012003.132208","journal-title":"Annu Rev Nutr"},{"key":"2125_CR6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/s0070-2137(01)80001-7","volume":"36","author":"CK Sen","year":"2000","unstructured":"Sen CK (2000) Cellular thiols and redox-regulated signal transduction. Curr Top Cell Regul 36:1\u201330. https:\/\/doi.org\/10.1016\/s0070-2137(01)80001-7","journal-title":"Curr Top Cell Regul"},{"key":"2125_CR7","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/s0070-2137(01)80007-8","volume":"36","author":"SM Deneke","year":"2000","unstructured":"Deneke SM (2000) Thiol-based antioxidants. Curr Top Cell Regul 36:151\u2013180. https:\/\/doi.org\/10.1016\/s0070-2137(01)80007-8","journal-title":"Curr Top Cell Regul"},{"issue":"6","key":"2125_CR8","doi-asserted-by":"publisher","first-page":"876","DOI":"10.1080\/02713683.2016.1256412","volume":"42","author":"M Tetiko\u011flu","year":"2017","unstructured":"Tetiko\u011flu M, Aktas S, Sa\u011fdik HM, \u00d6zcura F, U\u00e7ar F, Ko\u00e7ak H, Ne\u015felio\u011flu S, Erel \u00d6 (2017) Thiol disulfide homeostasis in pseudoexfoliation syndrome. Curr Eye Res 42(6):876\u2013879. https:\/\/doi.org\/10.1080\/02713683.2016.1256412","journal-title":"Curr Eye Res"},{"issue":"4","key":"2125_CR9","doi-asserted-by":"publisher","first-page":"690","DOI":"10.1177\/1120672119839582","volume":"30","author":"B Gulpamuk","year":"2020","unstructured":"Gulpamuk B, Elgin U, Sen E, Yilmazbas P, Neselioglu S, Erel O (2020) Evaluation of dynamic thiol-disulfide homeostasis in glaucoma patients and the correlation with retinal nerve fiber layer analysis. Eur J Ophthalmol 30(4):690\u2013699. https:\/\/doi.org\/10.1177\/1120672119839582","journal-title":"Eur J Ophthalmol"},{"issue":"9","key":"2125_CR10","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1080\/02713683.2017.1302592","volume":"42","author":"B Gulpamuk","year":"2017","unstructured":"Gulpamuk B, Ko\u00e7 M, Karatepe MS, Yildiz A, Erel O, Neselioglu S, Yilmazbas P (2017) Novel assay assessment of oxidative stress biomarkers in patients with keratoconus: thiol-disulfide homeostasis. Curr Eye Res 42(9):1215\u20131219. https:\/\/doi.org\/10.1080\/02713683.2017.1302592","journal-title":"Curr Eye Res"},{"issue":"3","key":"2125_CR11","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1080\/00365513.2017.1292539","volume":"77","author":"A Elbay","year":"2017","unstructured":"Elbay A, Ozer OF, Altinisik M, Elbay AE, Sezer T, Bayraktar H, Ozdemir H (2017) A novel tool reflecting the role of oxidative stress in the cataracts: thiol\/disulfide homeostasis. Scand J Clin Lab Invest 77(3):223\u2013227. https:\/\/doi.org\/10.1080\/00365513.2017.1292539","journal-title":"Scand J Clin Lab Invest"},{"issue":"11","key":"2125_CR12","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.3109\/02713683.2015.1127390","volume":"41","author":"EB Turkoglu","year":"2016","unstructured":"Turkoglu EB, Dikci S, \u00c7elik E, Erel \u00d6, Neselioglu S, Al\u0131\u015f\u0131k M, Koca C (2016) Thiol\/disulfide homeostasis in patients with central serous chorioretinopathy. Curr Eye Res 41(11):1489\u20131491. https:\/\/doi.org\/10.3109\/02713683.2015.1127390","journal-title":"Curr Eye Res"},{"issue":"12","key":"2125_CR13","doi-asserted-by":"publisher","first-page":"1584","DOI":"10.3109\/02713683.2016.1141965","volume":"41","author":"M Ar\u0131kanYorgun","year":"2016","unstructured":"Ar\u0131kanYorgun M, Toklu Y, Alt\u0131nkaynak H, Tanr\u0131verdi B, Ergin M, Bi\u00e7er C (2016) A novel tool for the assessment oxidative stress in age-related macular degeneration: thiol\/disulfide homeostasis revisited. Curr Eye Res 41(12):1584\u20131589. https:\/\/doi.org\/10.3109\/02713683.2016.1141965","journal-title":"Curr Eye Res"},{"issue":"10","key":"2125_CR14","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1001\/archopht.1997.01100160405001","volume":"115","author":"DT Tan","year":"1997","unstructured":"Tan DT, Chee SP, Dear KB, Lim AS (1997) Effect of pterygium morphology on pterygium recurrence in a controlled trial comparing conjunctival autografting with bare sclera excision. Arch Ophthalmol 115(10):1235\u20131240. https:\/\/doi.org\/10.1001\/archopht.1997.01100160405001","journal-title":"Arch Ophthalmol"},{"issue":"18","key":"2125_CR15","doi-asserted-by":"publisher","first-page":"326","DOI":"10.1016\/j.clinbiochem.2014.09.026","volume":"47","author":"O Erel","year":"2014","unstructured":"Erel O, Neselioglu S (2014) A novel and automated assay for thiol\/disulphide homeostasis. Clin Biochem 47(18):326\u2013332. https:\/\/doi.org\/10.1016\/j.clinbiochem.2014.09.026","journal-title":"Clin Biochem"},{"key":"2125_CR16","doi-asserted-by":"publisher","first-page":"149","DOI":"10.1186\/1471-2415-14-149","volume":"14","author":"A Kormanovski","year":"2014","unstructured":"Kormanovski A, Parra F, Jarillo-Luna A, Lara-Padilla E, Pacheco-Y\u00e9pez J, Campos-Rodriguez R (2014) Oxidant\/antioxidant state in tissue of primary and recurrent pterygium. BMC Ophthalmol 14:149. https:\/\/doi.org\/10.1186\/1471-2415-14-149","journal-title":"BMC Ophthalmol"},{"key":"2125_CR17","first-page":"1136","volume":"12","author":"MT Perra","year":"2006","unstructured":"Perra MT, Maxia C, Corbu A, Minerba L, Demurtas P, Colombari R, Murtas D, Bravo S, Piras F, Sirigu P (2006) Oxidative stress in pterygium: relationship between p53 and 8-hydroxydeoxyguanosine. Mol Vis 12:1136\u20131142 (PMID: 17093398)","journal-title":"Mol Vis"},{"key":"2125_CR18","doi-asserted-by":"crossref","unstructured":"Sun N, Zhang H (2018) Pyroptosis in pterygium pathogenesis. Biosci Rep 38(3):BSR20180282. 10.1042\/BSR20180282","DOI":"10.1042\/BSR20180282"},{"issue":"6","key":"2125_CR19","doi-asserted-by":"publisher","first-page":"2928","DOI":"10.1167\/iovs.09-4426","volume":"51","author":"E Peiretti","year":"2010","unstructured":"Peiretti E, Mandas A, Cocco P, Norfo C, Abete C, Angius F, Pani A, Vascellari S, Del Fiacco G, Cannas D, Diaz G, Dess\u00ec S, Fossarello M (2010) Glucose-6-phosphate-dehydrogenase deficiency as a risk factor for pterygium. Invest Ophthalmol Vis Sci 51(6):2928\u20132935. https:\/\/doi.org\/10.1167\/iovs.09-4426","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"2125_CR20","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1080\/15321819.2020.1726774","volume":"41","author":"A Ahmad","year":"2020","unstructured":"Ahmad A, Ahsan H (2020) Biomarkers of inflammation and oxidative stress in ophthalmic disorders. J Immunoassay Immunochem 41(3):257\u2013271. https:\/\/doi.org\/10.1080\/15321819.2020.1726774","journal-title":"J Immunoassay Immunochem"},{"key":"2125_CR21","doi-asserted-by":"publisher","unstructured":"Dogru M, Kojima T, Simsek C, Tsubota K (2018). Potential role of oxidative stress in ocular surface inflammation and dry eye disease. Invest Ophthalmol Vis Sci 59(14): DES163-DES168. https:\/\/doi.org\/10.1167\/iovs.17-23402","DOI":"10.1167\/iovs.17-23402"},{"issue":"1\u20133","key":"2125_CR22","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1016\/s1011-1344(98)00183-3","volume":"46","author":"J Longstreth","year":"1998","unstructured":"Longstreth J, de Gruijl FR, Kripke ML, Abseck S, Arnold F, Slaper HI, Velders G, Takizawa Y, van der Leun JC (1998) Health risks. J Photochem Photobiol B 46(1\u20133):20\u201339. https:\/\/doi.org\/10.1016\/s1011-1344(98)00183-3","journal-title":"J Photochem Photobiol B"},{"key":"2125_CR23","first-page":"443","volume":"17","author":"M Balci","year":"2011","unstructured":"Balci M, Sahin S, Mutlu FM, Ya\u011fci R, Karanci P, Yildiz M (2011) Investigation of oxidative stress in pterygium tissue. Mol Vis 17:443\u2013447 (PMID: 21321673)","journal-title":"Mol Vis"},{"key":"2125_CR24","doi-asserted-by":"publisher","first-page":"251584141984892","DOI":"10.1177\/2515841419848922","volume":"11","author":"BE Kurtul","year":"2019","unstructured":"Kurtul BE, Kabatas EU, Ozates S (2019) The correlation of routine hematological indices with pterygium. Ther Adv Ophthalmol 11:2515841419848922. https:\/\/doi.org\/10.1177\/2515841419848922","journal-title":"Ther Adv Ophthalmol"},{"issue":"8","key":"2125_CR25","doi-asserted-by":"publisher","first-page":"1724","DOI":"10.1016\/j.sjbs.2018.08.009","volume":"25","author":"M Rasool","year":"2018","unstructured":"Rasool M, Malik A, Abdul Basit Ashraf M, Arooj M, Kiran A, Waquar S, Ayyaz U, Zahid A, Zaheer A, Jabbar A, Zain M, Raza A, Mehmood A, BatoolQaisrani T, Mirza Z, Hussein Al-Qahtani M, Karim S, Haque A (2018) Role of diagnostic factors associated with antioxidative status and expression of matrix metalloproteinases (MMPs) in patients with cancer therapy induced ocular disorders. Saudi J Biol Sci 25(8):1724\u20131728. https:\/\/doi.org\/10.1016\/j.sjbs.2018.08.009","journal-title":"Saudi J Biol Sci"},{"issue":"6","key":"2125_CR26","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1097\/ICL.0000000000000620","volume":"45","author":"E Kilic-Toprak","year":"2019","unstructured":"Kilic-Toprak E, Toprak I, Caliskan S, Ozdemir Y, Demirtas O, Altintas F, Kucukatay V (2019) Oxidative stress and genotoxicity in pterygium: a systemic investigation. Eye Contact Lens 45(6):399\u2013404. https:\/\/doi.org\/10.1097\/ICL.0000000000000620","journal-title":"Eye Contact Lens"},{"key":"2125_CR27","doi-asserted-by":"publisher","unstructured":"Erel \u00d6, Erdo\u011fan S (2020), Thiol-disulfide homeostasis: an integrated approach with biochemical and clinical aspects. Turk J Med Sci, 50(SI-2): 1728\u20131738. https:\/\/doi.org\/10.3906\/sag-2003-64","DOI":"10.3906\/sag-2003-64"},{"issue":"5","key":"2125_CR28","doi-asserted-by":"publisher","first-page":"867","DOI":"10.7754\/Clin.Lab.2017.161117","volume":"63","author":"AK Erenler","year":"2017","unstructured":"Erenler AK, Yardan T (2017) Clinical utility of thiol\/disulfide homeostasis. Clin Lab 63(5):867\u2013870. https:\/\/doi.org\/10.7754\/Clin.Lab.2017.161117","journal-title":"Clin Lab"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-021-02125-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-021-02125-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-021-02125-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,2,27]],"date-time":"2022-02-27T07:06:19Z","timestamp":1645945579000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-021-02125-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,23]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["2125"],"URL":"https:\/\/doi.org\/10.1007\/s10792-021-02125-0","relation":{"has-preprint":[{"id-type":"doi","id":"10.21203\/rs.3.rs-237438\/v1","asserted-by":"object"}]},"ISSN":["0165-5701","1573-2630"],"issn-type":[{"value":"0165-5701","type":"print"},{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,23]]},"assertion":[{"value":"13 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 November 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 November 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The author declared that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The Institutional Review Board of the Duzce University, Duzce, Turkey approved this study (IRB: 2019\/152). All procedures adhered to the Declaration of Helsinki and HIPAA rules and were conducted in accordance with the approved protocol.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"This article does not contain any studies with animals performed by any of the authors.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal Research"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"Yes, obtained.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Yes, obtained.","order":7,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publish"}}]}}