{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T10:27:46Z","timestamp":1781605666124,"version":"3.54.5"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T00:00:00Z","timestamp":1648684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1007\/s10792-022-02306-5","type":"journal-article","created":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T10:03:51Z","timestamp":1648721031000},"page":"2581-2589","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Intercalary membrane break and detachment causes intrachoroidal cavitation in macular coloboma"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4479-9390","authenticated-orcid":false,"given":"Ramesh","family":"Venkatesh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikitha Gurram","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naresh Kumar","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay","family":"Chhablani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,3,31]]},"reference":[{"key":"2306_CR1","unstructured":"Coloboma of macula. https:\/\/www.orpha.net\/consor\/cgi-bin\/OC_Exp.php?lng=EN&Expert=98945. Accessed 19 Dec 2021"},{"key":"2306_CR2","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1080\/02713683.2020.1853779","volume":"46","author":"X Hou","year":"2021","unstructured":"Hou X, Guo Y, Liu J et al (2021) A systematic review of the clinical manifestations and diagnostic methods for macular coloboma. Curr Eye Res 46:913\u2013918. https:\/\/doi.org\/10.1080\/02713683.2020.1853779","journal-title":"Curr Eye Res"},{"key":"2306_CR3","doi-asserted-by":"publisher","first-page":"175","DOI":"10.3341\/kjo.2007.21.3.175","volume":"21","author":"JY Oh","year":"2007","unstructured":"Oh JY, Yu YS, Hwang J-M, Park KH (2007) Optical coherence tomographic finding in a case of macular coloboma. Korean J Ophthalmol 21:175. https:\/\/doi.org\/10.3341\/kjo.2007.21.3.175","journal-title":"Korean J Ophthalmol"},{"key":"2306_CR4","doi-asserted-by":"publisher","first-page":"544","DOI":"10.3129\/i09-277","volume":"45","author":"D Panagiotidis","year":"2010","unstructured":"Panagiotidis D, Karagiannis D, Theodossiadis P et al (2010) Atypical macular coloboma in a patient with adult vitelliform dystrophy. Can J Ophthalmol 45:544\u2013545. https:\/\/doi.org\/10.3129\/i09-277","journal-title":"Can J Ophthalmol"},{"key":"2306_CR5","doi-asserted-by":"publisher","first-page":"e73","DOI":"10.1016\/j.jfo.2018.05.011","volume":"42","author":"M El Bahloul","year":"2019","unstructured":"El Bahloul M, Younes S, Zahir F et al (2019) La dystrophie maculaire de la Caroline du Nord\u202f: \u00e0 propos d\u2019un cas. J Fr Ophtalmol 42:e73\u2013e77. https:\/\/doi.org\/10.1016\/j.jfo.2018.05.011","journal-title":"J Fr Ophtalmol"},{"key":"2306_CR6","doi-asserted-by":"publisher","first-page":"1040","DOI":"10.1016\/j.oret.2018.07.009","volume":"2","author":"IC Han","year":"2018","unstructured":"Han IC, Critser DB, Stone EM (2018) Swept-source OCT of a macular coloboma in NMNAT1-leber congenital amaurosis. Ophthalmol Retina 2:1040. https:\/\/doi.org\/10.1016\/j.oret.2018.07.009","journal-title":"Ophthalmol Retina"},{"key":"2306_CR7","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1007\/s10633-010-9214-5","volume":"120","author":"E Langwi\u0144ska-Wo\u015bko","year":"2010","unstructured":"Langwi\u0144ska-Wo\u015bko E, Szulborski K, Broniek-Kowalik K (2010) Late onset cone dystrophy. Doc Ophthalmol 120:215\u2013218. https:\/\/doi.org\/10.1007\/s10633-010-9214-5","journal-title":"Doc Ophthalmol"},{"key":"2306_CR8","doi-asserted-by":"publisher","first-page":"348","DOI":"10.4103\/0301-4738.158090","volume":"63","author":"DJ Mathew","year":"2015","unstructured":"Mathew DJ (2015) Bilateral macular colobomata: temporal dragging of optic disc. Indian J Ophthalmol 63:348\u2013350. https:\/\/doi.org\/10.4103\/0301-4738.158090","journal-title":"Indian J Ophthalmol"},{"key":"2306_CR9","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1177\/112067210401400619","volume":"14","author":"Y Hayasaka","year":"2004","unstructured":"Hayasaka Y, Hayasaka S (2004) Bilateral congenital macular coloboma in a boy with Down syndrome. Eur J Ophthalmol 14:565\u2013567. https:\/\/doi.org\/10.1177\/112067210401400619","journal-title":"Eur J Ophthalmol"},{"key":"2306_CR10","doi-asserted-by":"publisher","unstructured":"Plaza-Ramos P, Tabuenca-Del Barrio L, Zubicoa-Eneriz A, Goldaracena-Tanco B (2018) Michaelis-Manz syndrome: a case report. An Sist Sanit Navar 41:393\u2013396. https:\/\/doi.org\/10.23938\/ASSN.0377","DOI":"10.23938\/ASSN.0377"},{"key":"2306_CR11","doi-asserted-by":"publisher","first-page":"968","DOI":"10.1016\/0002-9394(70)92476-1","volume":"70","author":"RC Loh","year":"1970","unstructured":"Loh RC, Tan DS (1970) An unusual case of progeria-like dwarfism with bilateral macular coloboma. Am J Ophthalmol 70:968\u2013974. https:\/\/doi.org\/10.1016\/0002-9394(70)92476-1","journal-title":"Am J Ophthalmol"},{"key":"2306_CR12","doi-asserted-by":"publisher","first-page":"754","DOI":"10.1016\/j.jfo.2014.03.009","volume":"37","author":"F Amouyal","year":"2014","unstructured":"Amouyal F, Courjaret J-C, Denis D, Matonti F (2014) Colobome maculaire de Sorsby: fond d\u2019\u0153il et OCT spectral-domain. J Fr Ophtalmol 37:754. https:\/\/doi.org\/10.1016\/j.jfo.2014.03.009","journal-title":"J Fr Ophtalmol"},{"key":"2306_CR13","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1080\/13816810.2018.1498528","volume":"39","author":"AO Khan","year":"2018","unstructured":"Khan AO, Patel N, Ghazi NG et al (2018) Familial non-syndromic macular pseudocoloboma secondary to homozygous CLDN19 mutation. Ophthalmic Genet 39:577\u2013583. https:\/\/doi.org\/10.1080\/13816810.2018.1498528","journal-title":"Ophthalmic Genet"},{"key":"2306_CR14","doi-asserted-by":"publisher","first-page":"141","DOI":"10.1038\/sj.eye.6702961","volume":"23","author":"Y-H Wei","year":"2009","unstructured":"Wei Y-H, Yang C-M, Chen M-S et al (2009) Peripapillary intrachoroidal cavitation in high myopia: reappraisal. Eye 23:141\u2013144. https:\/\/doi.org\/10.1038\/sj.eye.6702961","journal-title":"Eye"},{"key":"2306_CR15","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1007\/s10792-019-01146-0","volume":"40","author":"R Venkatesh","year":"2020","unstructured":"Venkatesh R, Jain K, Aseem A et al (2020) Intrachoroidal cavitation in myopic eyes. Int Ophthalmol 40:31\u201341. https:\/\/doi.org\/10.1007\/s10792-019-01146-0","journal-title":"Int Ophthalmol"},{"key":"2306_CR16","doi-asserted-by":"publisher","first-page":"1073","DOI":"10.1001\/jamaophthalmol.2013.1598","volume":"131","author":"SD Schoenberger","year":"2013","unstructured":"Schoenberger SD, Agarwal A (2013) Intrachoroidal cavitation in North Carolina macular dystrophy. JAMA Ophthalmol 131:1073. https:\/\/doi.org\/10.1001\/jamaophthalmol.2013.1598","journal-title":"JAMA Ophthalmol"},{"key":"2306_CR17","doi-asserted-by":"publisher","first-page":"110085","DOI":"10.1016\/j.mehy.2020.110085","volume":"143","author":"A Markan","year":"2020","unstructured":"Markan A, Jain M, Singh R (2020) Secondary intrachoroidal cavitation in a case of iridofundal coloboma. Med Hypotheses 143:110085. https:\/\/doi.org\/10.1016\/j.mehy.2020.110085","journal-title":"Med Hypotheses"},{"key":"2306_CR18","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1038\/eye.2017.71","volume":"31","author":"CY Chung","year":"2017","unstructured":"Chung CY, Li SH, Li KKW (2017) Focal choroidal excavation\u2014morphological features and clinical correlation. Eye 31:1373\u20131379. https:\/\/doi.org\/10.1038\/eye.2017.71","journal-title":"Eye"},{"key":"2306_CR19","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1136\/bjo.11.3.99","volume":"11","author":"IC Mann","year":"1927","unstructured":"Mann IC (1927) On certain abnormal conditions of the macular region usually classed as colobomata. Br J Ophthalmol 11:99\u2013116. https:\/\/doi.org\/10.1136\/bjo.11.3.99","journal-title":"Br J Ophthalmol"},{"key":"2306_CR20","first-page":"457","volume":"103","author":"HD Schubert","year":"2005","unstructured":"Schubert HD (2005) Structural organization of choroidal colobomas of young and adult patients and mechanism of retinal detachment. Trans Am Ophthalmol Soc 103:457\u2013472","journal-title":"Trans Am Ophthalmol Soc"},{"key":"2306_CR21","doi-asserted-by":"publisher","first-page":"743","DOI":"10.4103\/0301-4738.122910","volume":"61","author":"G Lingam","year":"2013","unstructured":"Lingam G (2013) Pattern of blood vessels in eyes with coloboma. Indian J Ophthalmol 61:743. https:\/\/doi.org\/10.4103\/0301-4738.122910","journal-title":"Indian J Ophthalmol"},{"key":"2306_CR22","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1007\/s00417-014-2829-6","volume":"253","author":"T-C Chen","year":"2015","unstructured":"Chen T-C, Yang C-H, Sun J-P et al (2015) Macular retinal detachment associated with intrachoroidal cavitation in myopic patients. Graefes Arch Clin Exp Ophthalmol 253:1437\u20131446. https:\/\/doi.org\/10.1007\/s00417-014-2829-6","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"2306_CR23","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1159\/000339292","volume":"3","author":"M Akimoto","year":"2012","unstructured":"Akimoto M, Akagi T, Okazaki K, Chihara E (2012) Recurrent macular detachment and retinoschisis associated with intrachoroidal cavitation in a normal eye. Case Rep Ophthalmol 3:169\u2013174. https:\/\/doi.org\/10.1159\/000339292","journal-title":"Case Rep Ophthalmol"},{"key":"2306_CR24","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1097\/IAE.0000000000002111","volume":"39","author":"HL Feng","year":"2019","unstructured":"Feng HL, Sharma S, Stinnett S et al (2019) Identification of posterior segment pathology with en face retinal imaging using multicolor confocal scanning laser ophthalmoscopy. Retina (Philadelphia, Pa) 39:972\u2013979. https:\/\/doi.org\/10.1097\/IAE.0000000000002111","journal-title":"Retina (Philadelphia, Pa)"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-022-02306-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-022-02306-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-022-02306-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T09:24:14Z","timestamp":1658741054000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-022-02306-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,31]]},"references-count":24,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["2306"],"URL":"https:\/\/doi.org\/10.1007\/s10792-022-02306-5","relation":{},"ISSN":["1573-2630"],"issn-type":[{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,31]]},"assertion":[{"value":"19 October 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 March 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 March 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee (Narayana Nethralaya institutional review board \u2013 (C-2021-07-003) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards\u201d.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Informed consent was obtained from all individual participants included in the study. The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his\/her images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"This article does not contain any studies with animals performed by any of the authors.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}}]}}