{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T09:04:45Z","timestamp":1774343085301,"version":"3.50.1"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T00:00:00Z","timestamp":1667174400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"DOI":"10.1007\/s10792-022-02565-2","type":"journal-article","created":{"date-parts":[[2022,10,31]],"date-time":"2022-10-31T19:02:52Z","timestamp":1667242972000},"page":"1677-1686","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Posterior ocular manifestations following BNT162b2 mRNA COVID-19 vaccine: a case series"],"prefix":"10.1007","volume":"43","author":[{"given":"Shani","family":"Pillar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tamar","family":"Weinberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Radgonde","family":"Amer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,10,31]]},"reference":[{"key":"2565_CR1","doi-asserted-by":"publisher","first-page":"2603","DOI":"10.1056\/NEJMoa2034577","volume":"383","author":"FP Polack","year":"2020","unstructured":"Polack FP, Thomas SJ, Kitchin N et al (2020) Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. N Engl J Med 383:2603\u20132615","journal-title":"N Engl J Med"},{"issue":"6","key":"2565_CR2","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1080\/09273948.2021.1976221","volume":"29","author":"XL Ng","year":"2021","unstructured":"Ng XL, Betzler BK, Testi I et al (2021) Ocular adverse events after COVID-19 vaccination. Ocul Immunol Inflamm 29(6):1216\u20131224","journal-title":"Ocul Immunol Inflamm"},{"key":"2565_CR3","doi-asserted-by":"publisher","first-page":"2462","DOI":"10.1097\/IAE.0000000000003277","volume":"41","author":"T Rabinovitch","year":"2021","unstructured":"Rabinovitch T, Ben-Arie-Weintrob Y, Hareuveni-Blum T et al (2021) Uveitis after the BNT162b2 mRNA vaccination against SARS-CoV-2 infection: a possible association. Retina Phila Pa 41:2462\u20132471","journal-title":"Retina Phila Pa"},{"issue":"9","key":"2565_CR4","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1089\/jop.2021.0058","volume":"37","author":"P Neri","year":"2021","unstructured":"Neri P, Pichi F (2021) SARS-CoV-2 and the eye: the Pandora\u2019s box of ocular immunology. J Ocul Pharmacol Ther 37(9):502\u2013509","journal-title":"J Ocul Pharmacol Ther"},{"issue":"5","key":"2565_CR5","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1007\/s10792-020-01389-2","volume":"40","author":"P Neri","year":"2020","unstructured":"Neri P, Pichi F (2020) COVID-19 and the eye immunity: lesson learned from the past and possible new therapeutic insights. Int Ophthalmol 40(5):1057\u20131060","journal-title":"Int Ophthalmol"},{"issue":"10","key":"2565_CR6","doi-asserted-by":"publisher","first-page":"1131","DOI":"10.1001\/jamaophthalmol.2021.3477","volume":"139","author":"F Pichi","year":"2021","unstructured":"Pichi F, Aljneibi S, Neri P et al (2021) Association of ocular adverse events with inactivated COVID-19 vaccination in patients in Abu Dhabi. JAMA Ophthalmol 139(10):1131\u20131135","journal-title":"JAMA Ophthalmol"},{"key":"2565_CR7","doi-asserted-by":"publisher","first-page":"588","DOI":"10.1097\/ICU.0000000000000530","volume":"29","author":"RS Moorthy","year":"2018","unstructured":"Moorthy RS, Moorthy MS, Cunningham ET (2018) Drug-induced uveitis. Curr Opin Ophthalmol 29:588\u2013603","journal-title":"Curr Opin Ophthalmol"},{"key":"2565_CR8","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1093\/rheumatology\/36.1.120","volume":"36","author":"G Thurairajan","year":"1997","unstructured":"Thurairajan G, Hope-Ross MW, Situnayake RD et al (1997) Polyarthropathy, orbital myositis and posterior scleritis: an unusual adverse reaction to influenza vaccine. Br J Rheumatol 36:120\u2013123","journal-title":"Br J Rheumatol"},{"key":"2565_CR9","doi-asserted-by":"publisher","first-page":"1275","DOI":"10.1001\/jamaophthalmol.2013.4056","volume":"131","author":"D Sarraf","year":"2013","unstructured":"Sarraf D, Rahimy E, Fawzi AA et al (2013) Paracentral acute middle maculopathy: a new variant of acute macular neuroretinopathy associated with retinal capillary ischemia. JAMA Ophthalmol 131:1275\u20131287","journal-title":"JAMA Ophthalmol"},{"key":"2565_CR10","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.ajo.2015.04.004","volume":"160","author":"X Chen","year":"2015","unstructured":"Chen X, Rahimy E, Sergott RC et al (2015) Spectrum of retinal vascular diseases associated with paracentral acute middle maculopathy. Am J Ophthalmol 160:26-34.e1","journal-title":"Am J Ophthalmol"},{"key":"2565_CR11","first-page":"2352","volume":"34","author":"J Virgo","year":"2020","unstructured":"Virgo J, Mohamed M (2020) Paracentral acute middle maculopathy and acute macular neuroretinopathy following SARS-CoV-2 infection. Eye Lond Engl 34:2352\u20132353","journal-title":"Eye Lond Engl"},{"key":"2565_CR12","doi-asserted-by":"publisher","first-page":"2862","DOI":"10.4103\/ijo.IJO_1333_21","volume":"69","author":"S Vinzamuri","year":"2021","unstructured":"Vinzamuri S, Pradeep TG, Kotian R (2021) Bilateral paracentral acute middle maculopathy and acute macular neuroretinopathy following COVID-19 vaccination. Indian J Ophthalmol 69:2862\u20132864","journal-title":"Indian J Ophthalmol"},{"key":"2565_CR13","doi-asserted-by":"publisher","first-page":"5344","DOI":"10.3390\/jcm10225344","volume":"10","author":"F Bellinato","year":"2021","unstructured":"Bellinato F, Maurelli M, Gisondi P et al (2021) Cutaneous adverse reactions associated with SARS-CoV-2 vaccines. J Clin Med 10:5344","journal-title":"J Clin Med"},{"issue":"1","key":"2565_CR14","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.annder.2021.07.009","volume":"149","author":"N Kluger","year":"2022","unstructured":"Kluger N, Klimenko T, Bosonnet S (2022) Herpes simplex, herpes zoster and periorbital erythema flares after SARS-CoV-2 vaccination: 4 cases. Ann Dermatol Venereol 149(1):58\u201360","journal-title":"Ann Dermatol Venereol"},{"issue":"21","key":"2565_CR15","first-page":"02892","volume":"S0190\u20139622","author":"M Birabaharan","year":"2021","unstructured":"Birabaharan M, Kaelber DC, Karris MY (2021) Risk of herpes zoster reactivation after mRNA COVID-19 vaccination: a cohort study. J Am Acad Dermatol S0190\u20139622(21):02892\u201302899","journal-title":"J Am Acad Dermatol"},{"issue":"6","key":"2565_CR16","doi-asserted-by":"publisher","first-page":"1238","DOI":"10.1080\/09273948.2021.1986548","volume":"29","author":"MI Alkhalifah","year":"2021","unstructured":"Alkhalifah MI, Alsobki HE, Alwael HM et al (2021) Herpes simplex virus keratitis reactivation after SARS-CoV-2 BNT162b2 mRNA Vaccination: a report of two cases. Ocul Immunol Inflamm 29(6):1238\u20131240","journal-title":"Ocul Immunol Inflamm"},{"key":"2565_CR17","doi-asserted-by":"publisher","first-page":"701","DOI":"10.4103\/ijo.IJO_3009_20","volume":"69","author":"O Rehman","year":"2021","unstructured":"Rehman O, Ichhpujani P, Nayyar S et al (2021) COVID-19 pandemic and lockdown: changing trends in ophthalmology for in-patient and emergency services. Indian J Ophthalmol 69:701\u2013705","journal-title":"Indian J Ophthalmol"},{"key":"2565_CR18","doi-asserted-by":"crossref","unstructured":"Mishra SB, Mahendradas P, Kawali A et al (2021) Reactivation of varicella zoster infection presenting as acute retinal necrosis post COVID 19 vaccination in an Asian Indian male. Eur J Ophthalmol 11206721211046484","DOI":"10.1177\/11206721211046485"},{"key":"2565_CR19","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1186\/s40064-016-2223-4","volume":"5","author":"B Dogan","year":"2016","unstructured":"Dogan B, Erol MK, Cengiz A (2016) Vogt\u2013Koyanagi\u2013Harada disease following BCG vaccination and tuberculosis. Springerplus 5:603","journal-title":"Springerplus"},{"key":"2565_CR20","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1080\/09273948.2018.1483520","volume":"27","author":"AB Sood","year":"2019","unstructured":"Sood AB, O\u2019Keefe G, Bui D et al (2019) Vogt\u2013Koyanagi\u2013Harada disease associated with hepatitis B vaccination. Ocul Immunol Inflamm 27:524\u2013527","journal-title":"Ocul Immunol Inflamm"},{"key":"2565_CR21","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1080\/09273948.2019.1661498","volume":"29","author":"WR Campos","year":"2021","unstructured":"Campos WR, Cenachi SPF, Soares MS et al (2021) Vogt\u2013Koyanagi\u2013Harada-like disease following yellow fever vaccination. Ocul Immunol Inflamm 29:124\u2013127","journal-title":"Ocul Immunol Inflamm"},{"key":"2565_CR22","doi-asserted-by":"publisher","first-page":"98","DOI":"10.4103\/0301-4738.178141","volume":"64","author":"M Kim","year":"2016","unstructured":"Kim M (2016) Vogt\u2013Koyanagi\u2013Harada syndrome following influenza vaccination. Indian J Ophthalmol 64:98","journal-title":"Indian J Ophthalmol"},{"key":"2565_CR23","doi-asserted-by":"crossref","unstructured":"Pereima RR, Bonatti R, Crotti F et al (2021) Ocular Adverse Events following yellow fever vaccination: a case series. Ocul Immunol Inflamm 1\u20135","DOI":"10.1080\/09273948.2021.1887279"},{"key":"2565_CR24","doi-asserted-by":"crossref","unstructured":"Gallagher MJ, Yilmaz T, Foster CS (2009) Vogt\u2013Koyanagi\u2013Harada syndrome associated with bilateral serous macular detachments responsive to immunomodulatory therapy. Ophthalmic Surg Lasers Imaging Off J Int Soc Imaging Eye 40:345\u2013347","DOI":"10.3928\/15428877-20090430-25"},{"key":"2565_CR25","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s12348-021-00251-5","volume":"11","author":"I Papasavvas","year":"2021","unstructured":"Papasavvas I, Herbort CP (2021) Reactivation of Vogt\u2013Koyanagi\u2013Harada disease under control for more than 6 years, following anti-SARS-CoV-2 vaccination. J Ophthalmic Inflamm Infect 11:21","journal-title":"J Ophthalmic Inflamm Infect"},{"issue":"6","key":"2565_CR26","doi-asserted-by":"publisher","first-page":"1212","DOI":"10.1080\/09273948.2021.1974492","volume":"29","author":"LR Koong","year":"2021","unstructured":"Koong LR, Chee WK, Toh ZH et al (2021) Vogt\u2013Koyanagi\u2013Harada disease associated with COVID-19 mRNA vaccine. Ocul Immunol Inflamm 29(6):1212\u20131215","journal-title":"Ocul Immunol Inflamm"},{"key":"2565_CR27","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s40942-021-00319-3","volume":"7","author":"JJF Saraceno","year":"2021","unstructured":"Saraceno JJF, Souza GM, Dos Santos Finamor LP et al (2021) Vogt\u2013Koyanagi\u2013Harada syndrome following COVID-19 and ChAdOx1 nCoV-19 (AZD1222) vaccine. Int J Retina Vitr 7:49","journal-title":"Int J Retina Vitr"},{"issue":"22","key":"2565_CR28","first-page":"00672","volume":"S0161\u20136420","author":"RB Singh","year":"2022","unstructured":"Singh RB, Singh Parmar UP, Kahale F et al (2022) Vaccine-associated uveitis following SARS-CoV-2 vaccination: a CDC-VAERS database analysis. Ophthalmology S0161\u20136420(22):00672\u201300678","journal-title":"Ophthalmology"},{"issue":"10","key":"2565_CR29","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.ophtha.2022.05.015","volume":"129","author":"O Tomkins-Netzer","year":"2022","unstructured":"Tomkins-Netzer O, Sar S, Barnett-Griness O et al (2022) Association between vaccination with the BNT162b2 mRNA COVID-19 vaccine and non-infectious uveitis: a population-based study. Ophthalmology 129(10):1087\u20131095","journal-title":"Ophthalmology"},{"key":"2565_CR30","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1016\/j.ajo.2022.02.011","volume":"240","author":"MTM Wang","year":"2022","unstructured":"Wang MTM, Niederer RL, McGhee CNJ et al (2022) COVID-19 vaccination and the eye. Am J Ophthalmol 240:79\u201398","journal-title":"Am J Ophthalmol"},{"key":"2565_CR31","doi-asserted-by":"publisher","first-page":"239","DOI":"10.1038\/clpt.1981.154","volume":"30","author":"CA Naranjo","year":"1981","unstructured":"Naranjo CA, Busto U, Sellers EM et al (1981) A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 30:239\u2013245. https:\/\/doi.org\/10.1038\/clpt.1981.154","journal-title":"Clin Pharmacol Ther"},{"key":"2565_CR32","unstructured":"Holloway K (editor) and Green T (2003) World Health Organization. (2003). Drug and therapeutics committees: a practical guide. https:\/\/apps.who.int\/iris\/handle\/10665\/68553"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-022-02565-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-022-02565-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-022-02565-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T15:05:56Z","timestamp":1682867156000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-022-02565-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,31]]},"references-count":32,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2023,5]]}},"alternative-id":["2565"],"URL":"https:\/\/doi.org\/10.1007\/s10792-022-02565-2","relation":{},"ISSN":["1573-2630"],"issn-type":[{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,31]]},"assertion":[{"value":"9 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 October 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This is an observational study. The HMO Research Ethics Committee has confirmed that no ethical approval is required.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"This type of study does not require an informed consent.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}},{"value":"All authors thoroughly reviewed the manuscript and consented for publication.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publications"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}