{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T15:51:44Z","timestamp":1773157904229,"version":"3.50.1"},"reference-count":36,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T00:00:00Z","timestamp":1680912000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T00:00:00Z","timestamp":1680912000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100005743","name":"Universit\u00e0 Cattolica del Sacro Cuore","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005743","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>The aim this study is to determine anterior chamber parameters variations induced by PreserFlo MicroShunt implantation, in the early post-operative days.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>This is a prospective observational study on 48 eyes undergoing PreserFlo MicroShunt implantation alone (<jats:italic>n<\/jats:italic>\u2009=\u200930) or combined with phacoemulsification (<jats:italic>n<\/jats:italic>\u2009=\u200918). Anterior chamber depth (ACD) and volume (ACV), central corneal thickness (CCT) and total corneal astigmatism (TCA) were evaluated pre-operatively, post-operatively at day-1 and at 1\u00a0week with the Pentacam tomography.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Intraocular pressure decreased significantly from 20.9\u2009\u00b1\u20094.0 to 8.0\u2009\u00b1\u20092.8\u00a0mmHg (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.0001) and to 10.8\u2009\u00b1\u20093.7\u00a0mmHg (<jats:italic>p<\/jats:italic>\u2009=\u20090.0001) at day-1 and week-1, respectively. TCA varied significantly from baseline (1.5\u2009\u00b1\u20091.2 D) to both day 1 follow up (2.7\u2009\u00b1\u20091.9 D, <jats:italic>p<\/jats:italic>\u2009=\u20090.0003) and week 1 follow up (2.2\u2009\u00b1\u20091.6 D, <jats:italic>p<\/jats:italic>\u2009=\u20090.02). Nevertheless, only K1 showed a transient flattening at day 1, while K2 value didn\u2019t show any statistical variation in the early post-operative period. CCT value rose significantly at day 1 (547\u2009\u00b1\u200949 vs. 529\u2009\u00b1\u200932\u00a0\u00b5m at baseline, <jats:italic>p<\/jats:italic>\u2009=\u20090.04), but then returned toward pre-operative values at week 1 (537\u2009\u00b1\u200939\u00a0\u00b5m, <jats:italic>p<\/jats:italic>\u2009=\u20090.57). In contrast, ACD values changed insignificantly from 3.3\u2009\u00b1\u20090.9 to 3.7\u2009\u00b1\u20091.0\u00a0mm at day 1 (<jats:italic>p<\/jats:italic>\u2009=\u20090.21), and then stabilized at 3.4\u2009\u00b1\u20090.9\u00a0mm (<jats:italic>p<\/jats:italic>\u2009=\u20090.82) at week 1 follow up. ACV changed from 150.0\u2009\u00b1\u200936.2 to 159.5\u2009\u00b1\u200942.1 mm<jats:sup>3<\/jats:sup> at day 1 (<jats:italic>p<\/jats:italic>\u2009=\u20090.58), and successively to 153.9\u2009\u00b1\u200937.9 mm<jats:sup>3<\/jats:sup> at week 1 follow up (<jats:italic>p<\/jats:italic>\u2009=\u20090.96). The subgroup analysis in eyes undergoing standalone PreserFlo implantation didn\u2019t show significant changes in both ACD and ACV.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>PreserFlo implantation minimizes the anterior chamber modifications generated by traditional filtering surgery, inducing low and transient corneal and biometric changes only in the very early postoperative period and insignificant changes to ACD and ACV, label of its safety and minimal invasiveness.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10792-023-02697-z","type":"journal-article","created":{"date-parts":[[2023,4,8]],"date-time":"2023-04-08T20:26:15Z","timestamp":1680985575000},"page":"3035-3044","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Early post-operative anterior segment parameters modifications induced by PreserFlo MicroShunt in primary open-angle glaucoma"],"prefix":"10.1007","volume":"43","author":[{"given":"Gloria","family":"Gambini","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matteo Mario","family":"Carl\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico","family":"Giannuzzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Boselli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emanuele","family":"Crincoli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomaso","family":"Caporossi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Baldascino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umberto","family":"De Vico","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso","family":"Savastano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanislao","family":"Rizzo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,4,8]]},"reference":[{"issue":"7","key":"2697_CR1","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.1016\/j.ophtha.2011.03.028","volume":"118","author":"BA Francis","year":"2011","unstructured":"Francis BA, Singh K, Lin SC, Hodapp E, Jampel HD, Samples JR et al (2011) Novel glaucoma procedures: a report by the American academy of ophthalmology. 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