{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:49:48Z","timestamp":1791848988490,"version":"4.3.4"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T00:00:00Z","timestamp":1686787200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"DOI":"10.1007\/s10792-023-02762-7","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T08:02:11Z","timestamp":1686816131000},"page":"3549-3558","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Six-month repeated irradiation of 650\u00a0nm low-level red light reduces the risk of myopia in children: a randomized controlled trial"],"prefix":"10.1007","volume":"43","author":[{"given":"Lei","family":"Tian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong-Li","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li-Xin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-Qiang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-Xi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhang-Fang","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi-Bing","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Rong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Jie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,6,15]]},"reference":[{"issue":"5","key":"2762_CR1","doi-asserted-by":"publisher","first-page":"1036","DOI":"10.1016\/j.ophtha.2016.01.006","volume":"123","author":"BA Holden","year":"2016","unstructured":"Holden BA, Fricke TR, Wilson DA et al (2016) Global prevalence of myopia and high myopia and temporal trends from 2000 through 2050. Ophthalmology 123(5):1036\u20131042","journal-title":"Ophthalmology"},{"issue":"6","key":"2762_CR2","doi-asserted-by":"publisher","first-page":"386","DOI":"10.1097\/APO.0000000000000236","volume":"5","author":"PC Wu","year":"2016","unstructured":"Wu PC, Huang HM, Yu HJ et al (2016) Epidemiology of myopia. Asia Pac J Ophthalmol (Phila) 5(6):386\u2013393","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"issue":"10","key":"2762_CR3","doi-asserted-by":"publisher","first-page":"1096","DOI":"10.1001\/jamaophthalmol.2021.3303","volume":"139","author":"R Du","year":"2021","unstructured":"Du R, Xie S, Igarashi-Yokoi T et al (2021) Continued increase of axial length and its risk factors in adults with high myopia. JAMA Ophthalmol 139(10):1096\u20131103","journal-title":"JAMA Ophthalmol"},{"issue":"8","key":"2762_CR4","doi-asserted-by":"publisher","first-page":"e2121138","DOI":"10.1001\/jamanetworkopen.2021.21138","volume":"4","author":"MM Bikbov","year":"2021","unstructured":"Bikbov MM, Kazakbaeva GM, Rakhimova EM et al (2021) Prevalence factors associated with vision impairment and blindness among individuals 85 years and older in Russia. JAMA Netw Open 4(8):e2121138","journal-title":"JAMA Netw Open"},{"issue":"12","key":"2762_CR5","doi-asserted-by":"publisher","first-page":"e682","DOI":"10.1016\/S2468-2667(20)30254-1","volume":"5","author":"T Xu","year":"2020","unstructured":"Xu T, Wang B, Liu H et al (2020) Prevalence and causes of vision loss in China from 1990 to 2019: findings from the Global Burden of Disease Study 2019. Lancet Public Health 5(12):e682\u2013e691","journal-title":"Lancet Public Health"},{"issue":"12","key":"2762_CR6","doi-asserted-by":"publisher","first-page":"1355","DOI":"10.1001\/jamaophthalmol.2016.4009","volume":"134","author":"JW Tideman","year":"2016","unstructured":"Tideman JW, Snabel MC, Tedja MS et al (2016) Association of axial length with risk of uncorrectable visual impairment for europeans with myopia. JAMA Ophthalmol 134(12):1355\u20131363","journal-title":"JAMA Ophthalmol"},{"issue":"5","key":"2762_CR7","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1136\/bjophthalmol-2018-313308","volume":"104","author":"CY Cheng","year":"2020","unstructured":"Cheng CY, Wang N, Wong TY et al (2020) Prevalence and causes of vision loss in East Asia in 2015: magnitude, temporal trends and projections. Br J Ophthalmol 104(5):616\u2013622","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"2762_CR8","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1111\/cxo.12839","volume":"102","author":"P Cho","year":"2019","unstructured":"Cho P, Tan Q (2019) Myopia and orthokeratology for myopia control. Clin Exp Optom 102(4):364\u2013377","journal-title":"Clin Exp Optom"},{"issue":"5","key":"2762_CR9","doi-asserted-by":"publisher","first-page":"432","DOI":"10.1111\/cxo.12584","volume":"100","author":"P Sankaridurg","year":"2017","unstructured":"Sankaridurg P (2017) Contact lenses to slow progression of myopia. Clin Exp Optom 100(5):432\u2013437","journal-title":"Clin Exp Optom"},{"issue":"1","key":"2762_CR10","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.clae.2019.12.011","volume":"43","author":"N Logan","year":"2020","unstructured":"Logan N (2020) Myopia control and contact lenses. Cont Lens Anterior Eye 43(1):3","journal-title":"Cont Lens Anterior Eye"},{"issue":"9","key":"2762_CR11","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1097\/OPX.0b013e3181ea19c7","volume":"87","author":"P Sankaridurg","year":"2010","unstructured":"Sankaridurg P, Donovan L, Varnas S et al (2010) Spectacle lenses designed to reduce progression of myopia: 12-month results. Optom Vis Sci 87(9):631\u2013641","journal-title":"Optom Vis Sci"},{"key":"2762_CR12","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.ajo.2021.12.014","volume":"237","author":"JC Yam","year":"2022","unstructured":"Yam JC, Jiang Y, Lee J et al (2022) The association of choroidal thickening by atropine with treatment effects for myopia: two-year clinical trial of the low-concentration atropine for myopia progression (LAMP) study. Am J Ophthalmol 237:130\u2013138","journal-title":"Am J Ophthalmol"},{"key":"2762_CR13","doi-asserted-by":"crossref","unstructured":"Chia A, Chua W H, Wen L, et al (2014) Atropine for the treatment of childhood myopia: changes after stopping atropine 0.01%, 0.1% and 0.5%. Am J Ophthalmol 157(2):451\u2013457","DOI":"10.1016\/j.ajo.2013.09.020"},{"key":"2762_CR14","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.ajo.2021.12.014","volume":"237","author":"S Uzun","year":"2022","unstructured":"Uzun S, Uzun F (2022) The association of choroidal thickening by atropine with treatment effects for myopia: two-year clinical trial of the low-concentration atropine for myopia progression (LAMP) study. Am J Ophthalmol 237:130\u2013138","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"2762_CR15","doi-asserted-by":"publisher","first-page":"697","DOI":"10.1016\/j.ophtha.2015.11.010","volume":"123","author":"J Huang","year":"2016","unstructured":"Huang J, Wen D, Wang Q et al (2016) Efficacy comparison of 16 interventions for myopia control in children: a network meta-analysis. Ophthalmology 123(4):697\u2013708","journal-title":"Ophthalmology"},{"key":"2762_CR16","doi-asserted-by":"publisher","first-page":"718724","DOI":"10.3389\/fmed.2021.718724","volume":"8","author":"LL Foo","year":"2021","unstructured":"Foo LL, Lanca C, Wong CW et al (2021) Cost of myopia correction: a systematic review. Front Med (Lausanne) 8:718724","journal-title":"Front Med (Lausanne)"},{"issue":"11","key":"2762_CR17","first-page":"1535","volume":"104","author":"A Fu","year":"2020","unstructured":"Fu A, Stapleton F, Wei L et al (2020) Effect of low-dose atropine on myopia progression, pupil diameter and accommodative amplitude: low-dose atropine and myopia progression. Br J Ophthalmol 104(11):1535\u20131541","journal-title":"Br J Ophthalmol"},{"key":"2762_CR18","doi-asserted-by":"crossref","unstructured":"Chia A, Chua WH, Cheung YB, et al (2012) Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2). Ophthalmology 119(2):347\u2013354","DOI":"10.1016\/j.ophtha.2011.07.031"},{"issue":"11","key":"2762_CR19","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.1001\/jamaophthalmol.2020.3820","volume":"138","author":"S Wei","year":"2020","unstructured":"Wei S, Li SM, An W et al (2020) Safety and efficacy of low-dose atropine eyedrops for the treatment of myopia progression in chinese children: a randomized clinical trial. JAMA Ophthalmol 138(11):1178\u20131184","journal-title":"JAMA Ophthalmol"},{"issue":"2","key":"2762_CR20","doi-asserted-by":"publisher","first-page":"176","DOI":"10.7150\/ijms.39365","volume":"17","author":"Q Zhu","year":"2020","unstructured":"Zhu Q, Tang Y, Guo L et al (2020) Efficacy and safety of 1% atropine on retardation of moderate myopia progression in chinese school children. Int J Med Sci 17(2):176\u2013181","journal-title":"Int J Med Sci"},{"key":"2762_CR21","doi-asserted-by":"crossref","unstructured":"Yam J C, Jiang Y, Tang S M, et al (2019) Low-concentration atropine for myopia progression (LAMP) study: a randomized, double-blinded, placebo-controlled trial of 0.05%, 0.025%, and 0.01% atropine eye drops in myopia control. Ophthalmology 126(1):113\u2013124","DOI":"10.1016\/j.ophtha.2018.05.029"},{"issue":"11","key":"2762_CR22","doi-asserted-by":"publisher","first-page":"1142","DOI":"10.1001\/jama.2015.10803","volume":"314","author":"M He","year":"2015","unstructured":"He M, Xiang F, Zeng Y et al (2015) Effect of time spent outdoors at school on the development of myopia among children in China: a randomized clinical trial. JAMA 314(11):1142\u20131148","journal-title":"JAMA"},{"issue":"5","key":"2762_CR23","doi-asserted-by":"publisher","first-page":"509","DOI":"10.1016\/j.ophtha.2021.11.023","volume":"129","author":"Y Jiang","year":"2022","unstructured":"Jiang Y, Zhu Z, Tan X et al (2022) Effect of repeated low-level red-light therapy for myopia control in children: a multicenter randomized controlled trial. Ophthalmology 129(5):509\u2013519","journal-title":"Ophthalmology"},{"issue":"6","key":"2762_CR24","doi-asserted-by":"publisher","first-page":"2259","DOI":"10.1007\/s40123-022-00585-w","volume":"11","author":"L Tian","year":"2022","unstructured":"Tian L, Cao K, Ma DL et al (2022) Investigation of the efficacy and safety of 650 nm low-level red light for myopia control in children: a randomized controlled trial. Ophthalmol Ther 11(6):2259\u20132270","journal-title":"Ophthalmol Ther"},{"issue":"1","key":"2762_CR25","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1167\/iovs.63.1.8","volume":"63","author":"SM Li","year":"2022","unstructured":"Li SM, Wei S, Atchison DA et al (2022) Annual incidences and progressions of myopia and high myopia in Chinese schoolchildren based on a 5-year cohort study. Invest Ophthalmol Vis Sci 63(1):8","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"2762_CR26","doi-asserted-by":"publisher","first-page":"1017","DOI":"10.1001\/jamaophthalmol.2018.2658","volume":"136","author":"SK Wang","year":"2018","unstructured":"Wang SK, Guo Y, Liao C et al (2018) Incidence of and factors associated with myopia and high myopia in chinese children, based on refraction without cycloplegia. JAMA Ophthalmol 136(9):1017\u20131024","journal-title":"JAMA Ophthalmol"},{"issue":"2","key":"2762_CR27","doi-asserted-by":"publisher","first-page":"111","DOI":"10.4103\/tjo.tjo_110_18","volume":"10","author":"MC Ho","year":"2020","unstructured":"Ho MC, Hsieh YT, Shen EP et al (2020) Short-term refractive and ocular parameter changes after topical atropine. Taiwan J Ophthalmol 10(2):111\u2013115","journal-title":"Taiwan J Ophthalmol"},{"key":"2762_CR28","doi-asserted-by":"publisher","first-page":"4782536","DOI":"10.1155\/2019\/4782536","volume":"2019","author":"BP Sander","year":"2019","unstructured":"Sander BP, Collins MJ, Read SA (2019) Short-term effect of low-dose atropine and hyperopic defocus on choroidal thickness and axial length in young myopic adults. J Ophthalmol 2019:4782536","journal-title":"J Ophthalmol"},{"key":"2762_CR29","doi-asserted-by":"crossref","unstructured":"Li FF, Kam KW, Zhang Y, et al (2020) Differential effects on ocular biometrics by 0.05%, 0.025%, and 0.01% atropine: low-concentration atropine for myopia progression study. Ophthalmology 127(12):1603\u20131611","DOI":"10.1016\/j.ophtha.2020.06.004"},{"issue":"6","key":"2762_CR30","first-page":"1249","volume":"41","author":"D Troilo","year":"2000","unstructured":"Troilo D, Nickla DL, Wildsoet CF (2000) Choroidal thickness changes during altered eye growth and refractive state in a primate. Invest Ophthalmol Vis Sci 41(6):1249\u20131258","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"2762_CR31","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1006\/exer.2002.1142","volume":"74","author":"ME Fitzgerald","year":"2002","unstructured":"Fitzgerald ME, Wildsoet CF, Reiner A (2002) Temporal relationship of choroidal blood flow and thickness changes during recovery from form deprivation myopia in chicks. Exp Eye Res 74(5):561\u2013570","journal-title":"Exp Eye Res"},{"issue":"13","key":"2762_CR32","doi-asserted-by":"publisher","first-page":"9555","DOI":"10.1167\/iovs.11-8076","volume":"52","author":"X Ding","year":"2011","unstructured":"Ding X, Li J, Zeng J et al (2011) Choroidal thickness in healthy Chinese subjects. Invest Ophthalmol Vis Sci 52(13):9555\u20139560","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"2762_CR33","doi-asserted-by":"publisher","first-page":"e585","DOI":"10.1111\/aos.12631","volume":"93","author":"P Gupta","year":"2015","unstructured":"Gupta P, Saw SM, Cheung CY et al (2015) Choroidal thickness and high myopia: a case-control study of young Chinese men in Singapore. Acta Ophthalmol 93(7):e585\u2013e592","journal-title":"Acta Ophthalmol"},{"issue":"1","key":"2762_CR34","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.ophtha.2012.07.048","volume":"120","author":"WB Wei","year":"2013","unstructured":"Wei WB, Xu L, Jonas JB et al (2013) Subfoveal choroidal thickness: the Beijing Eye Study. Ophthalmology 120(1):175\u2013180","journal-title":"Ophthalmology"},{"issue":"6","key":"2762_CR35","doi-asserted-by":"publisher","first-page":"730","DOI":"10.5301\/ejo.5000965","volume":"27","author":"M Fontaine","year":"2017","unstructured":"Fontaine M, Gaucher D, Sauer A et al (2017) Choroidal thickness and ametropia in children: a longitudinal study. Eur J Ophthalmol 27(6):730\u2013734","journal-title":"Eur J Ophthalmol"},{"issue":"3","key":"2762_CR36","doi-asserted-by":"publisher","first-page":"307","DOI":"10.3109\/02713683.2014.973043","volume":"40","author":"W Chen","year":"2015","unstructured":"Chen W, Song H, Xie S et al (2015) Correlation of macular choroidal thickness with concentrations of aqueous vascular endothelial growth factor in high myopia. Curr Eye Res 40(3):307\u2013313","journal-title":"Curr Eye Res"},{"issue":"6","key":"2762_CR37","doi-asserted-by":"publisher","first-page":"4045","DOI":"10.1167\/iovs.15-16521","volume":"56","author":"R Jiang","year":"2015","unstructured":"Jiang R, Wang YX, Wei WB et al (2015) Peripapillary choroidal thickness in adult Chinese: the Beijing eye study. Invest Ophthalmol Vis Sci 56(6):4045\u20134052","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"2762_CR38","doi-asserted-by":"publisher","first-page":"730","DOI":"10.1111\/aos.14773","volume":"99","author":"Y Liu","year":"2021","unstructured":"Liu Y, Wang L, Xu Y et al (2021) The influence of the choroid on the onset and development of myopia: from perspectives of choroidal thickness and blood flow. Acta Ophthalmol 99(7):730\u2013738","journal-title":"Acta Ophthalmol"},{"key":"2762_CR39","doi-asserted-by":"publisher","first-page":"108332","DOI":"10.1016\/j.exer.2020.108332","volume":"202","author":"M Pan","year":"2021","unstructured":"Pan M, Guan Z, Reinach PS et al (2021) PPARgamma modulates refractive development and form deprivation myopia in Guinea pigs. Exp Eye Res 202:108332","journal-title":"Exp Eye Res"},{"key":"2762_CR40","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.ajo.2020.01.003","volume":"213","author":"S Xiong","year":"2020","unstructured":"Xiong S, He X, Zhang B et al (2020) Changes in choroidal thickness varied by age and refraction in children and adolescents: a 1-year longitudinal study. Am J Ophthalmol 213:46\u201356","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"2762_CR41","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s40662-020-00224-0","volume":"8","author":"X Zhou","year":"2021","unstructured":"Zhou X, Ye C, Wang X et al (2021) Choroidal blood perfusion as a potential \u201crapid predictive index\u201d for myopia development and progression. Eye Vis (London) 8(1):1","journal-title":"Eye Vis (London)"},{"issue":"15","key":"2762_CR42","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1167\/iovs.62.15.30","volume":"62","author":"X Zhou","year":"2021","unstructured":"Zhou X, Zhang S, Yang F et al (2021) Decreased choroidal blood perfusion induces myopia in guinea pigs. Invest Ophthalmol Vis Sci 62(15):30","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"13","key":"2762_CR43","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1167\/iovs.61.13.25","volume":"61","author":"X Zhou","year":"2020","unstructured":"Zhou X, Zhang S, Zhang G et al (2020) Increased choroidal blood perfusion can inhibit form deprivation myopia in guinea pigs. Invest Ophthalmol Vis Sci 61(13):25","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"2762_CR44","doi-asserted-by":"publisher","first-page":"833960","DOI":"10.3389\/fpubh.2022.833960","volume":"10","author":"R Xu","year":"2022","unstructured":"Xu R, Zhong P, Jan C et al (2022) Sex disparity in myopia explained by puberty among chinese adolescents from 1995 to 2014: a nationwide cross-sectional study. Front Public Health 10:833960","journal-title":"Front Public Health"},{"issue":"7","key":"2762_CR45","doi-asserted-by":"publisher","first-page":"882","DOI":"10.1136\/bjophthalmol-2015-307724","volume":"100","author":"AR Rudnicka","year":"2016","unstructured":"Rudnicka AR, Kapetanakis VV, Wathern AK et al (2016) Global variations and time trends in the prevalence of childhood myopia, a systematic review and quantitative meta-analysis: implications for aetiology and early prevention. Br J Ophthalmol 100(7):882\u2013890","journal-title":"Br J Ophthalmol"},{"issue":"5","key":"2762_CR46","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1016\/j.ophtha.2021.12.014","volume":"129","author":"S Hopf","year":"2022","unstructured":"Hopf S, Heidt F, Korb CA et al (2022) Five-year cumulative incidence and progression of myopic maculopathy in a German population. Ophthalmology 129(5):562\u2013570","journal-title":"Ophthalmology"},{"key":"2762_CR47","doi-asserted-by":"crossref","unstructured":"Liu M, Qin H, Wang Y, et al (2022) Refractive errors and risk factors for myopia in primary school students in Urumqi. Appl Bionics Biomech 2657455","DOI":"10.1155\/2022\/2657455"},{"key":"2762_CR48","doi-asserted-by":"publisher","unstructured":"Zhou Y, Huang X B, Cao X, et al (2022) Prevalence of myopia and influencing factors among high school students in Nantong, China: a cross-sectional study. Ophthalmic Res. https:\/\/doi.org\/10.1159\/000524293","DOI":"10.1159\/000524293"},{"issue":"2","key":"2762_CR49","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1001\/jamaophthalmol.2021.5067","volume":"140","author":"SS Lee","year":"2022","unstructured":"Lee SS, Lingham G, Sanfilippo PG et al (2022) Incidence and progression of myopia in early adulthood. JAMA Ophthalmol 140(2):162\u2013169","journal-title":"JAMA Ophthalmol"},{"issue":"11","key":"2762_CR50","doi-asserted-by":"publisher","first-page":"1489","DOI":"10.1136\/bjo.2005.071118","volume":"89","author":"SM Saw","year":"2005","unstructured":"Saw SM, Chua WH, Gazzard G et al (2005) Eye growth changes in myopic children in Singapore. Br J Ophthalmol 89(11):1489\u20131494","journal-title":"Br J Ophthalmol"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-023-02762-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-023-02762-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-023-02762-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T07:24:52Z","timestamp":1694762692000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-023-02762-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,15]]},"references-count":50,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2023,10]]}},"alternative-id":["2762"],"URL":"https:\/\/doi.org\/10.1007\/s10792-023-02762-7","relation":{},"ISSN":["1573-2630"],"issn-type":[{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6,15]]},"assertion":[{"value":"21 December 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 May 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}},{"value":"This study adhered to the tenets of the Declaration of Helsinki. Informed written consent was obtained from the children\u2019s guardian. This study was approved by the Ethics Committee, Beijing Tongren Hospital, Capital Medical University (No. TRECKY2021-239).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethics guidelines"}},{"value":"Not applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}