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In a retrospective study set, diurnal IOP profiles of 120 patients (205 eyes) within a 48-h period were analysed by regression analysis. Of those eyes, 44 were diagnosed to have glaucoma. The remaining eyes were used as healthy control group (HCG).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The overall mean IOP was 15.63\u00a0mmHg\u2009\u00b1\u20092.72\u00a0mmHg and mean ICAS was 23.92\u00b0\u2009\u00b1\u20094.74\u00b0. In the glaucoma cohort, mean IOP was 18.77\u2009\u00b1\u20091.86\u00a0mmHg and mean ICAS was 25.02\u00b0\u2009\u00b1\u20094.96\u00b0. In the HCG, mean IOP was 14.77\u2009\u00b1\u20092.25\u00a0mmHg and mean ICAS was 23.62\u00b0\u2009\u00b1\u20094.64\u00b0. In the total cohort, as well as in the subgroups (HCG or glaucoma), regression analysis showed no significant impact even of the minimum ICAS, which was larger than 10\u00b0, on average (<jats:italic>P<\/jats:italic>\u2009=\u20090.89), maximum (<jats:italic>P<\/jats:italic>\u2009=\u20090.88), and range of IOP (<jats:italic>P<\/jats:italic>\u2009=\u20090.49) within 48\u00a0h. The difference between glaucoma cohort and HCG cohort was significant in terms of IOP (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001), but not for minimum ICAS (<jats:italic>P<\/jats:italic>\u2009=\u20090.07). Chi-square test showed no increase in prevalence of IOP peaks of\u00a0\u2009&gt;\u200921\u00a0mmHg within 48\u00a0h in eyes with an angle between 10\u00b0 and 20\u00b0 (<jats:italic>P<\/jats:italic>\u2009=\u20090.18).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>An ICAS of larger than 10\u00b0 in HCG or glaucoma patients with an open-angle does not influence the minimum, average, maximum or range of IOP. Additionally, an angle size larger than 10\u00b0 does not allow the prediction of IOP changes in these two cohorts.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s10792-023-02823-x","type":"journal-article","created":{"date-parts":[[2023,9,2]],"date-time":"2023-09-02T03:26:12Z","timestamp":1693625172000},"page":"4067-4078","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of the iridocorneal angle size on the diurnal pressure profile in a glaucoma suspect cohort and patients with glaucoma"],"prefix":"10.1007","volume":"43","author":[{"given":"Michael","family":"M\u00fcller","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana","family":"Pavlovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Theresa","family":"Niermann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivana","family":"Pavlovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siegfried","family":"Priglinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6933-9585","authenticated-orcid":false,"given":"Thomas","family":"Kohnen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehdi","family":"Shajari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Mackert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,9,2]]},"reference":[{"key":"2823_CR1","doi-asserted-by":"publisher","unstructured":"Kahn HA, Milton RC (1980) Alternative definitions of open-angle glaucoma. 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M\u00fcller: <i>Consultant<\/i> for Th\u00e9a, Alcon, Novartis, Allergan. A. Pavlovic: No financial interests to declare. T. Niermann: No financial interests to declare. I. Pavlovic: No financial interests to declare. M. Mackert: No financial interests to declare. S. Priglinger: <i>Consultant<\/i> for Oertli and Novartis; <i>Grants<\/i> from Alcon, Bayer, Novartis, and Zeiss. M. Shajari: <i>Consultant<\/i> for Alcon, Zeiss, Staar, and Oculus. T. Kohnen: <i>Consultant and Research<\/i> for Abbott\/J&J, Alcon\/Novartis, Avedro, Oculentis, Oculus, Presbia, Schwind, Zeiss. <i>Consultant<\/i> for Allergan, Bausch & Lomb, Domp\u00e9, Geuder, Med Update, Merck, Rayner, Santen, Staar, Tear Lab, Th\u00e9a, Thieme, Ziemer. <i>Research<\/i> for Hoya.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"The study protocol of this retrospective study was approved by the ethics committee of the Goethe University, Frankfurt am Main, Germany.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was not required, because data were analysed in a pseudonymic way.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}