{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T19:23:27Z","timestamp":1793042607582,"version":"4.5.0"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T00:00:00Z","timestamp":1707523200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T00:00:00Z","timestamp":1707523200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum D\u00fcsseldorf. Anstalt \u00f6ffentlichen Rechts"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To evaluate the initial visual outcomes of Small Incision Lenticule Extraction (SMILE) Pro\u00ae using a 2\u00a0MHz femtosecond laser (VisuMax 800, Carl Zeiss Meditec) and to assess the efficacy, safety, predictability, accuracy, and complication rate.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective analysis included eyes which underwent the SMILE Pro\u00ae procedure using VisuMax 800 femtosecond laser to correct myopia. All surgeries were performed by one surgeon (DB). Follow-up was conducted 3\u00a0months postoperatively to evaluate visual outcomes after neuroadaptation, corrected visual acuity (CDVA) and intra- and postoperative complications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One hundred and fifty-two eyes of 82 patients (mean age 31\u2009\u00b1\u20096\u00a0years) results at 3\u00a0months are presented. The mean spherical equivalent (SE) was\u2009\u2212\u20094.44\u2009\u00b1\u20091.86 D preoperatively while -0.24\u2009\u00b1\u20090.32 D postoperatively. 99% of eyes achieved SE within\u2009\u00b1\u20091.0 D of attempted correction and 91% were within\u2009\u00b1\u20090.5 D. Efficacy index was 0.93 while the safety index was 1. No complications occurred intra- or postoperatively. No eyes lost more than 1 line of their preoperative CDVA. All highly myopic eyes (\u2212\u20096.25 to\u2009\u2212\u200910.00 D;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200918) achieved 20\/20 at 3\u00a0months postoperatively and were within 0.5 D from the attempted SE and no eyes lost more than 1 line of CDVA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The SMILE Pro\u00ae is a safe, efficient, and predictable procedure for the treatment of myopia and myopic astigmatism, with comparable results of conventional SMILE surgery. High myopic eyes achieve better results than low and moderate myopia. No complications were recorded in our patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10792-024-02915-2","type":"journal-article","created":{"date-parts":[[2024,2,10]],"date-time":"2024-02-10T06:02:10Z","timestamp":1707544930000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["Refractive outcomes of small lenticule extraction (SMILE) Pro\u00ae with a 2\u00a0MHz femtosecond laser"],"prefix":"10.1007","volume":"44","author":[{"given":"Amr","family":"Saad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karsten","family":"Klabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00fccella","family":"Kirca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florian A. T.","family":"Kretz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerd","family":"Auffarth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Detlev R. H.","family":"Breyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,2,10]]},"reference":[{"key":"2915_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.4103\/ijo.IJO_761_17","volume":"66","author":"S Ganesh","year":"2018","unstructured":"Ganesh S, Brar S, Arra R (2018) Refractive lenticule extraction small incision lenticule extraction: a new refractive surgery paradigm. Indian J Ophthalmol 66:10. https:\/\/doi.org\/10.4103\/ijo.IJO_761_17","journal-title":"Indian J Ophthalmol"},{"key":"2915_CR2","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1016\/j.jcrs.2008.05.033","volume":"34","author":"W Sekundo","year":"2008","unstructured":"Sekundo W, Kunert K, Russmann C et al (2008) First efficacy and safety study of femtosecond lenticule extraction for the correction of myopia. J Cataract Refract Surg 34:1513\u20131520. https:\/\/doi.org\/10.1016\/j.jcrs.2008.05.033","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR3","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.jcrs.2010.07.033","volume":"37","author":"R Shah","year":"2011","unstructured":"Shah R, Shah S, Sengupta S (2011) Results of small incision lenticule extraction: all-in-one femtosecond laser refractive surgery. J Cataract Refract Surg 37:127\u2013137. https:\/\/doi.org\/10.1016\/j.jcrs.2010.07.033","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR4","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1016\/j.jcrs.2015.02.006","volume":"41","author":"M Moshirfar","year":"2015","unstructured":"Moshirfar M, McCaughey MV, Reinstein DZ et al (2015) Small-incision lenticule extraction. J Cataract Refract Surg 41:652\u2013665. https:\/\/doi.org\/10.1016\/j.jcrs.2015.02.006","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR5","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1016\/j.jcrs.2004.01.001","volume":"30","author":"KA Walter","year":"2004","unstructured":"Walter KA, Stevenson AW (2004) Effect of environmental factors on myopic LASIK enhancement rates. J Cataract Refract Surg 30:798\u2013803. https:\/\/doi.org\/10.1016\/j.jcrs.2004.01.001","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR6","doi-asserted-by":"publisher","first-page":"164","DOI":"10.2174\/1874364101812010164","volume":"12","author":"IB Damgaard","year":"2018","unstructured":"Damgaard IB, Reffat M, Hjortdal J (2018) Review of corneal biomechanical properties following LASIK and SMILE for myopia and myopic astigmatism. Open Ophthalmol J 12:164\u2013174. https:\/\/doi.org\/10.2174\/1874364101812010164","journal-title":"Open Ophthalmol J"},{"key":"2915_CR7","doi-asserted-by":"publisher","first-page":"21","DOI":"10.3928\/1081597X-20211007-01","volume":"38","author":"MJTD Balgos","year":"2022","unstructured":"Balgos MJTD, Pi\u00f1ero DP, Canto-Cerdan M et al (2022) Comparison of the cost-effectiveness of SMILE, FS-LASIK, and PRK for myopia in a Private Eye Center in Spain. J Refract Surg 38:21\u201326. https:\/\/doi.org\/10.3928\/1081597X-20211007-01","journal-title":"J Refract Surg"},{"key":"2915_CR8","doi-asserted-by":"publisher","first-page":"e373","DOI":"10.1111\/AOS.14017","volume":"97","author":"M Li","year":"2019","unstructured":"Li M, Li M, Chen Y et al (2019) Five-year results of small incision lenticule extraction (SMILE) and femtosecond laser LASIK (FS-LASIK) for myopia. Acta Ophthalmol 97:e373\u2013e380. https:\/\/doi.org\/10.1111\/AOS.14017","journal-title":"Acta Ophthalmol"},{"key":"2915_CR9","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1136\/bjophthalmol-2018-312140","volume":"103","author":"T Han","year":"2019","unstructured":"Han T, Xu Y, Han X et al (2019) Three-year outcomes of small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) for myopia and myopic astigmatism. Br J Ophthalmol 103:565\u2013568. https:\/\/doi.org\/10.1136\/bjophthalmol-2018-312140","journal-title":"Br J Ophthalmol"},{"key":"2915_CR10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158176","volume":"11","author":"Z Shen","year":"2016","unstructured":"Shen Z, Shi K, Yu Y et al (2016) Small incision lenticule extraction (SMILE) versus femtosecond laser-assisted in situ keratomileusis (FS-LASIK) for myopia: a systematic review and meta-analysis. PLoS ONE 11:e0158176. https:\/\/doi.org\/10.1371\/journal.pone.0158176","journal-title":"PLoS ONE"},{"key":"2915_CR11","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1186\/s12886-020-01680-x","volume":"20","author":"T-Z Huang","year":"2020","unstructured":"Huang T-Z, Shen L, Yu X-N, Jin H-Y (2020) Risk factors and incidence of suction loss during small incision lenticule extraction (SMILE) in 8493 eyes. BMC Ophthalmol 20:412. https:\/\/doi.org\/10.1186\/s12886-020-01680-x","journal-title":"BMC Ophthalmol"},{"key":"2915_CR12","doi-asserted-by":"publisher","first-page":"2002","DOI":"10.1016\/j.jcrs.2014.04.031","volume":"40","author":"CW Wong","year":"2014","unstructured":"Wong CW, Chan C, Tan D, Mehta JS (2014) Incidence and management of suction loss in refractive lenticule extraction. J Cataract Refract Surg 40:2002\u20132010. https:\/\/doi.org\/10.1016\/j.jcrs.2014.04.031","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR13","doi-asserted-by":"publisher","unstructured":"Reinstein DZ, Archer TJ, Vida RS, Carp GI (2020) Suction stability management in small incision lenticule extraction: incidence and outcomes of suction loss in 4000 consecutive procedures. Acta Ophthalmol 98. https:\/\/doi.org\/10.1111\/aos.14215","DOI":"10.1111\/aos.14215"},{"key":"2915_CR14","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1186\/s12886-018-0965-1","volume":"18","author":"H-Y Jin","year":"2018","unstructured":"Jin H-Y, Wan T, Yu X-N et al (2018) Corneal higher-order aberrations of the anterior surface, posterior surface, and total cornea after small incision lenticule extraction (SMILE): high myopia versus mild to moderate myopia. BMC Ophthalmol 18:295. https:\/\/doi.org\/10.1186\/s12886-018-0965-1","journal-title":"BMC Ophthalmol"},{"key":"2915_CR15","doi-asserted-by":"publisher","first-page":"294","DOI":"10.3928\/1081597X-20230301-02","volume":"39","author":"DZ Reinstein","year":"2023","unstructured":"Reinstein DZ, Archer TJ, Potter JG et al (2023) Refractive and visual outcomes of SMILE for compound myopic astigmatism with the VISUMAX 800. J Refract Surg 39:294\u2013301. https:\/\/doi.org\/10.3928\/1081597X-20230301-02","journal-title":"J Refract Surg"},{"key":"2915_CR16","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1007\/s40123-021-00383-w","volume":"10","author":"M Moshirfar","year":"2021","unstructured":"Moshirfar M, Tukan AN, Bundogji N et al (2021) Ectasia after corneal refractive surgery: a systematic review. Ophthalmol Ther 10:753\u2013776. https:\/\/doi.org\/10.1007\/s40123-021-00383-w","journal-title":"Ophthalmol Ther"},{"key":"2915_CR17","unstructured":"Carl Zeiss Meditec AG (2016) VisuMax femtosecond laser. Small incision lenticule extraction for the correction of high myopia. FDA Professional Use Information. 60"},{"key":"2915_CR18","doi-asserted-by":"publisher","first-page":"144","DOI":"10.3928\/1081-597X-20050301-08","volume":"21","author":"K Pesudovs","year":"2005","unstructured":"Pesudovs K (2005) Involvement of neural adaptation in the recovery of vision after laser refractive surgery. J Refract Surg 21:144\u2013147. https:\/\/doi.org\/10.3928\/1081-597X-20050301-08","journal-title":"J Refract Surg"},{"key":"2915_CR19","doi-asserted-by":"publisher","first-page":"975","DOI":"10.3928\/1081597X-20091016-01","volume":"25","author":"DZ Reinstein","year":"2009","unstructured":"Reinstein DZ, Waring GO (2009) Graphic reporting of outcomes of refractive surgery. J Refract Surg 25:975\u2013978. https:\/\/doi.org\/10.3928\/1081597X-20091016-01","journal-title":"J Refract Surg"},{"key":"2915_CR20","doi-asserted-by":"publisher","first-page":"335","DOI":"10.1136\/bjo.2009.174284","volume":"95","author":"W Sekundo","year":"2011","unstructured":"Sekundo W, Kunert KS, Blum M (2011) Small incision corneal refractive surgery using the small incision lenticule extraction (SMILE) procedure for the correction of myopia and myopic astigmatism: results of a 6 month prospective study. Br J Ophthalmol 95:335\u2013339. https:\/\/doi.org\/10.1136\/bjo.2009.174284","journal-title":"Br J Ophthalmol"},{"key":"2915_CR21","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1016\/j.jcrs.2012.07.021","volume":"38","author":"A Vestergaard","year":"2012","unstructured":"Vestergaard A, Ivarsen AR, Asp S, Hjortdal J\u00d8 (2012) Small-incision lenticule extraction for moderate to high myopia: predictability, safety, and patient satisfaction. J Cataract Refract Surg 38:2003\u20132010. https:\/\/doi.org\/10.1016\/j.jcrs.2012.07.021","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR22","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/s40662-015-0024-4","volume":"2","author":"E Chansue","year":"2015","unstructured":"Chansue E, Tanehsakdi M, Swasdibutra S, McAlinden C (2015) Efficacy, predictability and safety of small incision lenticule extraction (SMILE). Eye and Vision 2:14. https:\/\/doi.org\/10.1186\/s40662-015-0024-4","journal-title":"Eye and Vision"},{"key":"2915_CR23","doi-asserted-by":"publisher","first-page":"822","DOI":"10.1016\/j.ophtha.2013.11.006","volume":"121","author":"A Ivarsen","year":"2014","unstructured":"Ivarsen A, Asp S, Hjortdal J (2014) Safety and complications of more than 1500 small-incision lenticule extraction procedures. Ophthalmology 121:822\u2013828. https:\/\/doi.org\/10.1016\/j.ophtha.2013.11.006","journal-title":"Ophthalmology"},{"key":"2915_CR24","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1055\/a-0914-3152","volume":"236","author":"DRH Breyer","year":"2019","unstructured":"Breyer DRH, Beckers L, Hagen P et al (2019) [Comparison of long-term results with small incision refractive lenticule extraction (ReLEX SMILE) vs. Femto-LASIK] Vergleich der Langzeitergebnisse bei Small Incision Refractive Lenticule Extraction (ReLEx SMILE) und Femto-LASIK. Klin Monbl Augenheilkd 236:1201\u20131207. https:\/\/doi.org\/10.1055\/a-0914-3152","journal-title":"Klin Monbl Augenheilkd"},{"key":"2915_CR25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0242059","volume":"16","author":"Y Fu","year":"2021","unstructured":"Fu Y, Yin Y, Wu X et al (2021) Clinical outcomes after small-incision lenticule extraction versus femtosecond laser-assisted LASIK for high myopia: a meta-analysis. PLoS ONE 16:e0242059. https:\/\/doi.org\/10.1371\/journal.pone.0242059","journal-title":"PLoS ONE"},{"key":"2915_CR26","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1186\/s12886-021-02048-5","volume":"21","author":"Y Yin","year":"2021","unstructured":"Yin Y, Lu Y, Xiang A et al (2021) Comparison of the optical quality after SMILE and FS-LASIK for high myopia by OQAS and iTrace analyzer: a one-year retrospective study. BMC Ophthalmol 21:292. https:\/\/doi.org\/10.1186\/s12886-021-02048-5","journal-title":"BMC Ophthalmol"},{"key":"2915_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2018\/5893126","volume":"2018","author":"A A\u011fca","year":"2018","unstructured":"A\u011fca A, \u00c7ak\u0131r \u0130, T\u00fcl\u00fc Ayg\u00fcn B et al (2018) Visual and refractive outcomes of small-incision lenticule extraction in high myopia: 5-year results. J Ophthalmol 2018:1\u20136. https:\/\/doi.org\/10.1155\/2018\/5893126","journal-title":"J Ophthalmol"},{"key":"2915_CR28","doi-asserted-by":"publisher","first-page":"719","DOI":"10.3928\/1081597X-20150923-11","volume":"31","author":"IB Pedersen","year":"2015","unstructured":"Pedersen IB, Ivarsen A, Hjortdal J (2015) Three-year results of small incision lenticule extraction for high myopia: refractive outcomes and aberrations. J Refract Surg 31:719\u2013724. https:\/\/doi.org\/10.3928\/1081597X-20150923-11","journal-title":"J Refract Surg"},{"key":"2915_CR29","doi-asserted-by":"publisher","first-page":"412","DOI":"10.1097\/01.APO.0000580128.27272.bb","volume":"8","author":"Y Wang","year":"2019","unstructured":"Wang Y, Ma J (2019) Future developments in SMILE: higher degree of myopia and hyperopia. Asia-Pacific J Ophthalmol 8:412\u2013416. https:\/\/doi.org\/10.1097\/01.APO.0000580128.27272.bb","journal-title":"Asia-Pacific J Ophthalmol"},{"key":"2915_CR30","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1167\/iovs.12-11155","volume":"54","author":"C Strohmaier","year":"2013","unstructured":"Strohmaier C, Runge C, Seyeddain O et al (2013) Profiles of intraocular pressure in human donor eyes during femtosecond laser procedures\u2014a comparative study. Invest Opthalmol Vis Sci 54:522. https:\/\/doi.org\/10.1167\/iovs.12-11155","journal-title":"Invest Opthalmol Vis Sci"},{"key":"2915_CR31","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3928\/1081597X-20101210-01","volume":"27","author":"JM Vetter","year":"2011","unstructured":"Vetter JM, Holzer MP, Teping C et al (2011) Intraocular pressure during corneal flap preparation: comparison among four femtosecond lasers in porcine eyes. J Refract Surg 27:427\u2013433. https:\/\/doi.org\/10.3928\/1081597X-20101210-01","journal-title":"J Refract Surg"},{"key":"2915_CR32","doi-asserted-by":"publisher","first-page":"423","DOI":"10.1016\/j.jcrs.2013.08.056","volume":"40","author":"RC Hall","year":"2014","unstructured":"Hall RC, Rosman M, Chan C et al (2014) Patient and surgeon experience during laser in situ keratomileusis using 2 femtosecond laser systems. J Cataract Refract Surg 40:423\u2013429. https:\/\/doi.org\/10.1016\/j.jcrs.2013.08.056","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR33","doi-asserted-by":"publisher","first-page":"796","DOI":"10.1016\/j.jcrs.2017.03.039","volume":"43","author":"Y Wang","year":"2017","unstructured":"Wang Y, Ma J, Zhang J et al (2017) Incidence and management of intraoperative complications during small-incision lenticule extraction in 3004 cases. J Cataract Refract Surg 43:796\u2013802. https:\/\/doi.org\/10.1016\/j.jcrs.2017.03.039","journal-title":"J Cataract Refract Surg"},{"key":"2915_CR34","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1016\/j.ophtha.2019.09.006","volume":"127","author":"M Ang","year":"2020","unstructured":"Ang M, Farook M, Htoon HM, Mehta JS (2020) Randomized clinical trial comparing femtosecond LASIK and small-incision lenticule extraction. Ophthalmology 127:724\u2013730. https:\/\/doi.org\/10.1016\/j.ophtha.2019.09.006","journal-title":"Ophthalmology"},{"key":"2915_CR35","doi-asserted-by":"publisher","first-page":"92","DOI":"10.3928\/1081597X-20171218-01","volume":"34","author":"IB Damgaard","year":"2018","unstructured":"Damgaard IB, Ang M, Farook M et al (2018) Intraoperative patient experience and postoperative visual quality after SMILE and LASIK in a randomized, paired-eye, controlled study. J Refract Surg 34:92\u201399. https:\/\/doi.org\/10.3928\/1081597X-20171218-01","journal-title":"J Refract Surg"},{"key":"2915_CR36","doi-asserted-by":"publisher","first-page":"686","DOI":"10.3928\/1081597X-20160608-02","volume":"32","author":"M Liu","year":"2016","unstructured":"Liu M, Wang J, Zhong W et al (2016) Impact of suction loss during small incision lenticule extraction (SMILE). J Refract Surg 32:686\u2013692. https:\/\/doi.org\/10.3928\/1081597X-20160608-02","journal-title":"J Refract Surg"},{"key":"2915_CR37","doi-asserted-by":"publisher","first-page":"2711","DOI":"10.4103\/ijo.IJO_3258_20","volume":"68","author":"M Asif","year":"2020","unstructured":"Asif M, Bafna R, Mehta J et al (2020) Complications of small incision lenticule extraction. Indian J Ophthalmol 68:2711. https:\/\/doi.org\/10.4103\/ijo.IJO_3258_20","journal-title":"Indian J Ophthalmol"},{"key":"2915_CR38","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1097\/ICO.0000000000000383","volume":"34","author":"M Liu","year":"2015","unstructured":"Liu M, Sun Y, Wang D et al (2015) Decentration of optical zone center and its impact on visual outcomes following SMILE. Cornea 34:392\u2013397. https:\/\/doi.org\/10.1097\/ICO.0000000000000383","journal-title":"Cornea"},{"key":"2915_CR39","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1097\/01.APO.0000580132.98159.FA","volume":"8","author":"R Shah","year":"2019","unstructured":"Shah R (2019) History and results; indications and contraindications of SMILE compared with LASIK. Asia Pac J Ophthalmol (Phila) 8:371\u2013376. https:\/\/doi.org\/10.1097\/01.APO.0000580132.98159.FA","journal-title":"Asia Pac J Ophthalmol (Phila)"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-024-02915-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-024-02915-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-024-02915-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T11:21:26Z","timestamp":1741864886000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-024-02915-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,10]]},"references-count":39,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2915"],"URL":"https:\/\/doi.org\/10.1007\/s10792-024-02915-2","relation":{},"ISSN":["1573-2630"],"issn-type":[{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,10]]},"assertion":[{"value":"10 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 December 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"D.R.H. Breyer, MD, FWCRS is paid consultant to Carl Zeiss Meditec AG. The other authors do not have any conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"52"}}