{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T08:20:41Z","timestamp":1763367641831,"version":"3.38.0"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T00:00:00Z","timestamp":1708992000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T00:00:00Z","timestamp":1708992000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Guangdong Medical Science and Technology Research Foundation Project","award":["no. A2021389","no. A2021389","no. A2021389"],"award-info":[{"award-number":["no. A2021389","no. A2021389","no. A2021389"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"DOI":"10.1007\/s10792-024-02986-1","type":"journal-article","created":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T13:02:24Z","timestamp":1709038944000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Analysis and validation of potential ICD-related biomarkers in development of myopia using machine learning"],"prefix":"10.1007","volume":"44","author":[{"given":"Yun","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanli","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meixia","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,2,27]]},"reference":[{"issue":"5","key":"2986_CR1","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.ophtha.2018.01.033","volume":"125","author":"BS Modjtahedi","year":"2018","unstructured":"Modjtahedi BS, Ferris FL 3rd, Hunter DG, Fong DS (2018) Public health burden and potential interventions for myopia. Ophthalmology 125(5):628\u2013630","journal-title":"Ophthalmology"},{"issue":"23","key":"2986_CR2","doi-asserted-by":"crossref","first-page":"e20410","DOI":"10.1097\/MD.0000000000020410","volume":"99","author":"Z Yu","year":"2020","unstructured":"Yu Z, Wang X, Zhao X, Li D, Duan J (2020) The effectiveness and safety of acupuncture for patients with myopia: a protocol for a systematic review and meta-analysis. Medicine (Baltimore) 99(23):e20410","journal-title":"Medicine (Baltimore)"},{"issue":"5","key":"2986_CR3","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1097\/APO.0000000000000559","volume":"11","author":"M Li","year":"2022","unstructured":"Li M, Xu L, Tan CS, Lanca C, Foo LL, Sabanayagam C, Saw SM (2022) Systematic review and meta-analysis on the impact of COVID-19 pandemic-related lifestyle on myopia. Asia Pac J Ophthalmol (Phila) 11(5):470\u2013480","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"key":"2986_CR4","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/OPX.0000000000001367","volume":"96","author":"MA Bullimore","year":"2019","unstructured":"Bullimore MA, Brennan NA (2019) Myopia control: why each diopter matters. Optom Vis Sci 96:463\u2013465","journal-title":"Optom Vis Sci"},{"key":"2986_CR5","first-page":"3633","volume":"43","author":"DO Mutti","year":"2002","unstructured":"Mutti DO, Mitchell GL, Moeschberger ML, Jones LA, Zadnik K (2002) Parental myopia, near work, school achievement, and children\u2019s refractive error. Invest Ophthalmol Vis Sci 43:3633\u20133640","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"2986_CR6","doi-asserted-by":"crossref","first-page":"e0140419","DOI":"10.1371\/journal.pone.0140419","volume":"10","author":"HM Huang","year":"2015","unstructured":"Huang HM, Chang DS, Wu PC (2015) The association between near work activities and myopia in children\u2014a systematic review and meta-analysis. PLOS ONE 10(10):e0140419","journal-title":"PLOS ONE"},{"issue":"11","key":"2986_CR7","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1167\/iovs.63.11.5","volume":"63","author":"J Liu","year":"2022","unstructured":"Liu J, Wei H, Yang Z et al (2022) Enhanced apoptosis in choroidal tissues in lens-induced myopia guinea pigs by activating the RASA signaling pathway. Invest Ophthalmol Vis Sci 63(11):5","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"2986_CR8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12964-022-00970-9","volume":"20","author":"S Liu","year":"2022","unstructured":"Liu S, Chen T, Chen B, Liu Y, Lu X, Li J (2022) Lrpap1 deficiency leads to myopia through TGF-\u03b2-induced apoptosis in zebrafish. Cell Commun Signal 20(1):162","journal-title":"Cell Commun Signal"},{"issue":"1","key":"2986_CR9","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1038\/s41572-020-00231-4","volume":"6","author":"PN Baird","year":"2020","unstructured":"Baird PN, Saw SM, Lanca C, Guggenheim JA, Smith Iii EL, Zhou X, Matsui KO, Wu PC, Sankaridurg P, Chia A, Rosman M, Lamoureux EL, Man R, He M (2020) Myopia Nat Rev Dis Primers 6(1):99","journal-title":"Myopia Nat Rev Dis Primers"},{"issue":"43","key":"2986_CR10","doi-asserted-by":"crossref","first-page":"e2104689118","DOI":"10.1073\/pnas.2104689118","volume":"118","author":"M Pan","year":"2021","unstructured":"Pan M, Zhao F, Xie B, Wu H, Zhang S, Ye C, Guan Z, Kang L, Zhang Y, Zhou X, Lei Y, Wang Q, Wang L, Yang F, Zhao C, Qu J, Zhou X (2021) Dietary \u03c9-3 polyunsaturated fatty acids are protective for myopia. Proc Natl Acad Sci USA 118(43):e2104689118","journal-title":"Proc Natl Acad Sci USA"},{"key":"2986_CR11","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3389\/fphys.2020.00463","volume":"11","author":"S M\u00e9rida","year":"2020","unstructured":"M\u00e9rida S, Villar VM, Navea A, Desco C, Sancho-Tello M, Peris C, Bosch-Morell F (2020) Imbalance between oxidative stress and growth factors in human high myopia. Front Physiol 11:463","journal-title":"Front Physiol"},{"key":"2986_CR12","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/s41418-017-0012-4","volume":"25","author":"L Galluzzi","year":"2018","unstructured":"Galluzzi L, Vitale I, Aaronson S, Abrams J, Adam D, Agostinis P et al (2018) Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018. Cell Death Differ 25:486\u2013541","journal-title":"Cell Death Differ"},{"key":"2986_CR13","doi-asserted-by":"crossref","first-page":"1001320","DOI":"10.3389\/fimmu.2022.1001320","volume":"13","author":"M Turhon","year":"2022","unstructured":"Turhon M, Maimaiti A, Gheyret D, Axier A, Rexiati N, Kadeer K, Su R, Wang Z, Chen X, Cheng X, Zhang Yand Aisha M (2022) An immunogenic cell death-related regulators classification patterns and immune microenvironment infiltration characterization in intracranial aneurysm based on machine learning. Front Immunol 13:1001320","journal-title":"Front Immunol"},{"issue":"9","key":"2986_CR14","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1016\/j.ajpath.2020.06.002","volume":"190","author":"F Zhao","year":"2020","unstructured":"Zhao F, Wu H, Reinach PS, Wu Y, Zhai Y, Lei Y, Ma L, Su Y, Chen Y, Li F, Liu X, Srinivasalu N, Qu J, Zhou X (2020) Up-regulation of matrix metalloproteinase-2 by scleral monocyte-derived macrophages contributes to myopia development. Am J Pathol 190(9):1888\u20131908","journal-title":"Am J Pathol"},{"issue":"1","key":"2986_CR15","doi-asserted-by":"crossref","first-page":"80","DOI":"10.3390\/ijms24010080","volume":"24","author":"J Qi","year":"2023","unstructured":"Qi J, Pan W, Peng T, Zeng L, Li X, Chen Z, Yang Z, Xu H (2023) Higher circulating levels of neutrophils and basophils are linked to myopic retinopathy. Int J Mol Sci 24(1):80","journal-title":"Int J Mol Sci"},{"issue":"4","key":"2986_CR16","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cytogfr.2013.05.001","volume":"24","author":"O Kepp","year":"2013","unstructured":"Kepp O, Menger L, Vacchelli E, Locher C, Adjemian S, Yamazaki T, Martins I, Sukkurwala AQ, Michaud M, Senovilla L, Galluzzi L, Kroemer G, Zitvogel L (2013) Crosstalk between ER stress and immunogenic cell death. Cytokine Growth Factor Rev 24(4):311\u2013318","journal-title":"Cytokine Growth Factor Rev"},{"issue":"5","key":"2986_CR17","doi-asserted-by":"crossref","first-page":"1776570","DOI":"10.1080\/23723556.2020.1776570","volume":"7","author":"J Humeau","year":"2020","unstructured":"Humeau J, Bezu L, Kepp O, Kroemer G (2020) EIF2\u03b1 phosphorylation: a hallmark of both autophagy and immunogenic cell death. Mol Cell Oncol 7(5):1776570","journal-title":"Mol Cell Oncol"},{"issue":"1","key":"2986_CR18","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/s41392-023-01570-w","volume":"8","author":"X Chen","year":"2023","unstructured":"Chen X, Shi C, He M, Xiong S, Xia X (2023) Endoplasmic reticulum stress: molecular mechanism and therapeutic targets. Signal Transduct Target Ther 8(1):352","journal-title":"Signal Transduct Target Ther"},{"key":"2986_CR19","doi-asserted-by":"crossref","first-page":"814814","DOI":"10.3389\/fphar.2022.814814","volume":"13","author":"Y Zhu","year":"2022","unstructured":"Zhu Y, Bian JF, Lu DQ, To CH, Lam CS, Li KK, Yu FJ, Gong BT, Wang Q, Ji XW, Zhang HM, Nian H, Lam TC, Wei RH (2022) Alteration of EIF2 signaling, glycolysis, and dopamine secretion in form-deprived myopia in response to 1% atropine treatment: evidence from interactive iTRAQ-MS and SWATH-MS proteomics using a guinea pig model. Front Pharmacol 13:814814","journal-title":"Front Pharmacol"},{"issue":"30","key":"2986_CR20","first-page":"E7091","volume":"115","author":"H Wu","year":"2018","unstructured":"Wu H, Chen W, Zhao F, Zhou Q, Reinach PS, Deng L, Ma L, Luo S, Srinivasalu N, Pan M, Hu Y, Pei X, Sun J, Ren R, Xiong Y, Zhou Z, Zhang S, Tian G, Fang J, Zhang L, Lang J, Wu D, Zeng C, Qu J, Zhou X (2018) Scleral hypoxia is a target for myopia control. Proc Natl Acad Sci USA 115(30):E7091\u2013E7100","journal-title":"Proc Natl Acad Sci USA"},{"key":"2986_CR21","doi-asserted-by":"crossref","first-page":"i427","DOI":"10.1093\/bioinformatics\/btz333","volume":"35","author":"H Climente-Gonz\u00e1lez","year":"2019","unstructured":"Climente-Gonz\u00e1lez H, Azencott CA, Kaski S, Yamada M (2019) Block HSIC lasso: model-free biomarker detection for ultra-high dimensional data. Bioinformatics 35:i427\u2013i435","journal-title":"Bioinformatics"},{"key":"2986_CR22","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1478-811X-7-18","volume":"7","author":"BN Davis","year":"2009","unstructured":"Davis BN, Hata A (2009) Regulation of MicroRNA biogenesis: a miRiad of mechanisms. Cell Commun Signal 7:18","journal-title":"Cell Commun Signal"},{"key":"2986_CR23","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00417-016-3532-6","volume":"255","author":"B Jiang","year":"2017","unstructured":"Jiang B, Huo Y, Gu Y, Wang J (2017) The role of microRNAs in myopia. Graefes Arch Clin Exp Ophthalmol 255:7\u201313","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"2986_CR24","doi-asserted-by":"crossref","first-page":"2732","DOI":"10.1167\/iovs.11-9272","volume":"53","author":"KC Chen","year":"2012","unstructured":"Chen KC, Hsi E, Hu F et al (2012) MicroRNA-\u00ad328 may influence myopiadevelopment by mediating the PAX6 gene. Invest Ophthalmol Vis Sci 53:2732\u20132739","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"2986_CR25","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.gene.2018.11.030","volume":"687","author":"E Kunceviciene","year":"2019","unstructured":"Kunceviciene E, Liutkeviciene R, Budiene B et al (2019) Independent association of whole blood miR-328 expression and polymorphism at 3\u2019UTR of the PAX6 gene with myopia. Gene 687:151\u2013155","journal-title":"Gene"},{"key":"2986_CR26","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1007\/s00417-020-04634-7","volume":"258","author":"M Wang","year":"2020","unstructured":"Wang M, Yang Z-K, Liu H et al (2020) Genipin inhibits the scleral expression of miR-\u00ad29 and MMP2 and promotes COL1A1 expression in myopic eyes of guinea pigs. Graefes Arch Clin Exp Ophthalmol. 258:1031\u20131038","journal-title":"Graefes Arch Clin Exp Ophthalmol."},{"key":"2986_CR27","doi-asserted-by":"crossref","first-page":"3629","DOI":"10.3390\/ijms20153629","volume":"20","author":"Y Tanaka","year":"2019","unstructured":"Tanaka Y, Kurihara T, Hagiwara Y, Ikeda S-I, Mori K, Jiang X, Torii H, Tsubota K (2019) Ocular-component-specific miRNA expression in a murine model of lens-induced myopia. Int J Mol Sci 20:3629","journal-title":"Int J Mol Sci"},{"key":"2986_CR28","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.exer.2005.08.009","volume":"82","author":"JA Summers Rada","year":"2006","unstructured":"Summers Rada JA, Shelton S, Norton TT (2006) The sclera and myopia. Exp Eye Res 82:185\u2013200","journal-title":"Exp Eye Res"},{"key":"2986_CR29","doi-asserted-by":"crossref","first-page":"E365","DOI":"10.1097\/OPX.0b013e31820b053d","volume":"88","author":"JT Siegwart Jr","year":"2011","unstructured":"Siegwart JT Jr, Norton TT (2011) Perspective: how might emmetropization and genetic factors produce myopia in normal eyes? Optom Vis Sci. 88:E365\u2013E372","journal-title":"Optom Vis Sci."},{"key":"2986_CR30","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/bs.pmbts.2015.05.005","volume":"134","author":"R Metlapally","year":"2015","unstructured":"Metlapally R, Wildsoet CF (2015) Scleral mechanisms underlying ocular growth and myopia. Prog Mol Biol Transl Sci 134:241\u2013248","journal-title":"Prog Mol Biol Transl Sci"},{"key":"2986_CR31","doi-asserted-by":"crossref","first-page":"100773","DOI":"10.1016\/j.preteyeres.2019.100773","volume":"74","author":"C Boote","year":"2020","unstructured":"Boote C, Sigal IA, Grytz R, Hua YI, Nguyen TD, Girard MJA (2020) Scleral structure and biomechanics. Prog Retin Eye Res 74:100773","journal-title":"Prog Retin Eye Res"},{"key":"2986_CR32","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.exer.2013.03.008","volume":"114","author":"JA Summers","year":"2013","unstructured":"Summers JA (2013) The choroid as a sclera growth regulator. Exp Eye Res 114:120\u2013127","journal-title":"Exp Eye Res"},{"key":"2986_CR33","doi-asserted-by":"crossref","first-page":"4096","DOI":"10.1016\/j.visres.2006.07.033","volume":"46","author":"JC Chen","year":"2006","unstructured":"Chen JC, Brown B, Schmid KL (2006) Evaluation of inner retinal function in myopia using oscillatory potentials of the multifocal electroretinogram. Vision Res 46:4096\u20134103","journal-title":"Vision Res"},{"key":"2986_CR34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.exer.2013.02.014","volume":"114","author":"X Zhu","year":"2013","unstructured":"Zhu X (2013) Temporal integration of visual signals in lens compensation (a review). Exp Eye Res. 114:69\u201376","journal-title":"Exp Eye Res."},{"key":"2986_CR35","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/bs.pmbts.2015.06.014","volume":"134","author":"Y Zhang","year":"2015","unstructured":"Zhang Y, Wildsoet CF (2015) RPE and choroid mechanisms underlying ocular growth and myopia. Prog Mol Biol Transl Sci 134:221\u2013240","journal-title":"Prog Mol Biol Transl Sci"},{"issue":"1","key":"2986_CR36","doi-asserted-by":"crossref","first-page":"2102","DOI":"10.1038\/s41467-021-22041-2","volume":"12","author":"X Zhu","year":"2021","unstructured":"Zhu X, Du Y, Li D, Xu J, Wu Q, He W, Zhang K, Zhu J, Guo L, Qi M, Liu A, Qi J, Wang G, Meng J, Yang Z, Zhang K, Lu Y (2021) Aberrant TGF-\u03b21 signaling activation by MAF underlies pathological lens growth in high myopia. Nat Commun 12(1):2102","journal-title":"Nat Commun"},{"issue":"D1","key":"2986_CR37","doi-asserted-by":"crossref","first-page":"D991","DOI":"10.1093\/nar\/gks1193","volume":"41","author":"T Barrett","year":"2012","unstructured":"Barrett T, Wilhite SE, Ledoux P et al (2012) NCBI GEO: archive for functional genomics data sets-update. Nucleic Acids Res 41(D1):D991\u2013D995","journal-title":"Nucleic Acids Res"},{"issue":"7","key":"2986_CR38","doi-asserted-by":"crossref","first-page":"e47","DOI":"10.1093\/nar\/gkv007","volume":"43","author":"M Ritchie","year":"2015","unstructured":"Ritchie M et al (2015) limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res 43(7):e47","journal-title":"Nucleic Acids Res"},{"key":"2986_CR39","unstructured":"Kolde R (2019) Pheatmap: pretty heatmaps. https:\/\/cran.r-project.org\/web\/packages\/pheatmap\/pheatmap.pdf"},{"key":"2986_CR40","first-page":"213","volume":"8","author":"H Wickham","year":"2009","unstructured":"Wickham H (2009) ggplot2: Elegant graphics for data analysis. J Issue 8:213","journal-title":"J Issue"},{"issue":"3","key":"2986_CR41","first-page":"100141","volume":"2","author":"T Wu","year":"2021","unstructured":"Wu T, Hu E, Xu S, Chen M, Guo P, Dai Z et al (2021) ClusterProfiler 4.0: a universal enrichment tool for interpreting omics data. Innovation 2(3):100141","journal-title":"Innovation"},{"issue":"1","key":"2986_CR42","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/75556","volume":"25","author":"M Ashburner","year":"2000","unstructured":"Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM et al (2000) Gene ontology: tool for the unification of biology. The gene ontology Consortium. Nat Genet 25(1):25\u201329","journal-title":"Nat Genet"},{"issue":"D1","key":"2986_CR43","doi-asserted-by":"crossref","first-page":"D419","DOI":"10.1093\/nar\/gky1038","volume":"47","author":"H Mi","year":"2019","unstructured":"Mi H, Muruganujan A, Ebert D, Huang X, Thomas PD (2019) PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools. Nucleic Acids Res 47(D1):D419-426","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"2986_CR44","doi-asserted-by":"crossref","first-page":"D325","DOI":"10.1093\/nar\/gkaa1113","volume":"49","author":"Consortium TGO","year":"2021","unstructured":"Consortium TGO (2021) The gene ontology resource: enriching a GOld mine. Nucleic Acids Res 49(D1):D325-d334","journal-title":"Nucleic Acids Res"},{"issue":"D1","key":"2986_CR45","doi-asserted-by":"crossref","first-page":"D587","DOI":"10.1093\/nar\/gkac963","volume":"51","author":"M Kanehisa","year":"2023","unstructured":"Kanehisa M, Furumichi M, Sato Y, Kawashima M, Ishiguro-Watanabe M (2023) KEGG for taxonomy-based analysis of pathways and genomes. Nucleic Acids Res 51(D1):D587\u2013D592","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"2986_CR46","doi-asserted-by":"crossref","first-page":"e1069938","DOI":"10.1080\/2162402X.2015.1069938","volume":"5","author":"AD Garg","year":"2015","unstructured":"Garg AD, De Ruysscher D, Agostinis P (2015) Immunological metagene signatures derived from immunogenic cancer cell death associate with improved survival of patients with lung, breast or ovarian malignancies: a large-scale meta-analysis. Oncoimmunology 5(2):e1069938","journal-title":"Oncoimmunology"},{"issue":"3","key":"2986_CR47","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.3390\/ijms24033033","volume":"24","author":"Z Wang","year":"2023","unstructured":"Wang Z, Liu J, Wang Y, Guo H, Li F, Cao Y, Zhao L, Chen H (2023) Identification of key biomarkers associated with immunogenic cell death and their regulatory mechanisms in severe acute pancreatitis based on WGCNA and machine learning. Int J Mol Sci 24(3):3033","journal-title":"Int J Mol Sci"},{"issue":"1","key":"2986_CR48","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1186\/s13148-019-0730-1","volume":"11","author":"S Engebretsen","year":"2019","unstructured":"Engebretsen S, Bohlin J (2019) Statistical predictions with glmnet. Clin Epigenet 11(1):123","journal-title":"Clin Epigenet"},{"issue":"24","key":"2986_CR49","doi-asserted-by":"crossref","first-page":"5944","DOI":"10.7150\/jca.35785","volume":"10","author":"S Zhang","year":"2019","unstructured":"Zhang S, Tong YX, Zhang XH, Zhang YJ, Xu XS, Xiao AT, Chao TF, Gong JP (2019) A novel and validated nomogram to predict overall survival for gastric neuroendocrine neoplasms. J Cancer 10(24):5944\u20135954","journal-title":"J Cancer"},{"key":"2986_CR50","doi-asserted-by":"crossref","first-page":"15545","DOI":"10.1073\/pnas.0506580102","volume":"102","author":"A Subramanian","year":"2005","unstructured":"Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA et al (2005) Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 102:15545\u201315550","journal-title":"Proc Natl Acad Sci USA"},{"issue":"1","key":"2986_CR51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2105-14-7","volume":"14","author":"S H\u00e4nzelmann","year":"2013","unstructured":"H\u00e4nzelmann S, Castelo R, Guinney J (2013) GSVA: gene set variation analysis for microarray and RNA-seq data. BMC Bioinform 14(1):1\u201315","journal-title":"BMC Bioinform"},{"key":"2986_CR52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7554\/eLife.05005","volume":"4","author":"V Agarwal","year":"2015","unstructured":"Agarwal V, Bell GW, Nam JW, Bartel DP (2015) Predicting effective microRNA target sites in mammalian mRNAs. Elife 4:1","journal-title":"Elife"},{"issue":"11","key":"2986_CR53","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1101\/gr.1239303","volume":"13","author":"P Shannon","year":"2003","unstructured":"Shannon P, Markiel A, Ozier O, Baliga NS, Wang JT, Ramage D, Amin N, Schwikowski B, Ideker T (2003) Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res 13(11):2498\u20132504","journal-title":"Genome Res"},{"key":"2986_CR54","doi-asserted-by":"crossref","unstructured":"Wallman J, Winawer J (2004) Homeostasis of eye growth and the question of myopia. Neuron 43:447\u2013468. This is the first comprehensive review of animal research on refractive development; it provides a unique perspective on how vision regulates ocular growth and refractive development","DOI":"10.1016\/j.neuron.2004.08.008"},{"key":"2986_CR55","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S1350-9462(02)00063-0","volume":"22","author":"NA McBrien","year":"2003","unstructured":"McBrien NA, Gentle A (2003) Role of the sclera in the development and pathological complications of myopia. Prog Retin Eye Res 22:307\u2013338","journal-title":"Prog Retin Eye Res"},{"issue":"2","key":"2986_CR56","first-page":"146","volume":"61","author":"E Lomdina","year":"2015","unstructured":"Lomdina E, Tarutta E, Markossian G, Aksenova J, Smirnova T, Bedretdinov A (2015) Sclera as the target tissue in progressive myopia. Pomeranian J Life Sci 61(2):146\u2013152","journal-title":"Pomeranian J Life Sci"},{"issue":"9","key":"2986_CR57","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1080\/15592294.2020.1834917","volume":"16","author":"K Wen","year":"2021","unstructured":"Wen K, Zhang Y, Li Y, Wang Q, Sun J (2021) Comprehensive analysis of transcriptome-wide m6A methylome in the anterior capsule of the lens of high myopia patients. Epigenetics 16(9):955\u2013968","journal-title":"Epigenetics"},{"issue":"4","key":"2986_CR58","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/s12276-021-00607-w","volume":"53","author":"H Chen","year":"2021","unstructured":"Chen H, Yan T, Song Z, Ying S, Wu B, Ju X, Yang X, Qu J, Wu W, Zhang Z, Wang Y (2021) MD2 blockade prevents modified LDL-induced retinal injury in diabetes by suppressing NADPH oxidase-4 interaction with Toll-like receptor-4. Exp Mol Med 53(4):681\u2013694","journal-title":"Exp Mol Med"},{"issue":"5","key":"2986_CR59","doi-asserted-by":"crossref","first-page":"165683","DOI":"10.1016\/j.bbadis.2020.165683","volume":"1866","author":"Y Zhang","year":"2020","unstructured":"Zhang Y, Chen H, Zhang W, Cai Y, Shan P, Wu D, Zhang B, Liu H, Khan ZA, Liang G (2020) Arachidonic acid inhibits inflammatory responses by binding to myeloid differentiation factor-2 (MD2) and preventing MD2\/toll-like receptor 4 signaling activation. Biochim Biophys Acta Mol Basis Dis 1866(5):165683","journal-title":"Biochim Biophys Acta Mol Basis Dis"},{"issue":"4","key":"2986_CR60","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.jaci.2017.08.034","volume":"141","author":"TX Lu","year":"2018","unstructured":"Lu TX, Rothenberg ME (2018) MicroRNA. J Allergy Clin Immunol 141(4):1202\u20131207","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"2986_CR61","doi-asserted-by":"crossref","first-page":"4","DOI":"10.2174\/2211536607666180827111633","volume":"8","author":"M Tafrihi","year":"2019","unstructured":"Tafrihi M, Hasheminasab E (2019) MiRNAs: biology, biogenesis, their web-based tools, and databases. Microrna 8(1):4\u201327","journal-title":"Microrna"},{"issue":"1","key":"2986_CR62","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00417-016-3532-6","volume":"255","author":"B Jiang","year":"2017","unstructured":"Jiang B, Huo Y, Gu Y, Wang J (2017) The role of microRNAs in myopia. Graefes Arch Clin Exp Ophthalmol 255(1):7\u201313","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"2986_CR63","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1186\/s13046-019-1356-z","volume":"38","author":"H Yan","year":"2019","unstructured":"Yan H, Li H, Silva MA et al (2019) LncRNA FLVCR1-AS1 mediates miR-513\/YAP1 signaling to promote cell progression, migration, invasion and EMT process in ovarian cancer. J Exp Clin Cancer Res 38:356","journal-title":"J Exp Clin Cancer Res"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-024-02986-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-024-02986-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-024-02986-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T15:49:36Z","timestamp":1741880976000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-024-02986-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,27]]},"references-count":63,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["2986"],"URL":"https:\/\/doi.org\/10.1007\/s10792-024-02986-1","relation":{},"ISSN":["1573-2630"],"issn-type":[{"type":"electronic","value":"1573-2630"}],"subject":[],"published":{"date-parts":[[2024,2,27]]},"assertion":[{"value":"31 January 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 October 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 February 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"116"}}