{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T16:10:15Z","timestamp":1741882215239,"version":"3.38.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["Code 001","Code 001"],"award-info":[{"award-number":["Code 001","Code 001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020431","name":"Funda\u00e7\u00e3o Lemann","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020431","id-type":"DOI","asserted-by":"publisher"}]},{"name":"IPEPO Vision Institute"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"DOI":"10.1007\/s10792-024-03070-4","type":"journal-article","created":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T09:02:20Z","timestamp":1710752540000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Objective demonstration of eyelid spasm relief with smartphone and custom software in hemifacial spasm patients"],"prefix":"10.1007","volume":"44","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0400-8013","authenticated-orcid":false,"given":"Gustavo R.","family":"Gameiro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Yabumoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8574-2879","authenticated-orcid":false,"given":"Midori H.","family":"Osaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas G.","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Schor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-2141","authenticated-orcid":false,"given":"Tammy H.","family":"Osaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,3,18]]},"reference":[{"key":"3070_CR1","doi-asserted-by":"publisher","first-page":"531","DOI":"10.1002\/MDS.22998","volume":"25","author":"C Colosimo","year":"2010","unstructured":"Colosimo C, Berardelli A (2010) An early image of hemifacial spasm: Edouard Brissaud contribution. Mov Disord 25:531\u2013533. https:\/\/doi.org\/10.1002\/MDS.22998","journal-title":"Mov Disord"},{"key":"3070_CR2","doi-asserted-by":"publisher","first-page":"1459","DOI":"10.1016\/j.ophtha.2018.03.013","volume":"125","author":"JR Bilyk","year":"2018","unstructured":"Bilyk JR, Yen MT, Bradley EA et al (2018) Chemodenervation for the treatment of facial dystonia a report by the American academy of ophthalmology. Ophthalmology 125:1459\u20131467. https:\/\/doi.org\/10.1016\/j.ophtha.2018.03.013","journal-title":"Ophthalmology"},{"key":"3070_CR3","doi-asserted-by":"publisher","first-page":"1233","DOI":"10.1001\/ARCHNEUR.1990.00530110095023","volume":"47","author":"RG Auger","year":"1990","unstructured":"Auger RG, Whisnant JP (1990) Hemifacial spasm in Rochester and Olmsted County, Minnesota, 1960\u20131984. Arch Neurol 47:1233\u20131234. https:\/\/doi.org\/10.1001\/ARCHNEUR.1990.00530110095023","journal-title":"Arch Neurol"},{"issue":"4","key":"3070_CR4","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1007\/S00702-007-0768-7","volume":"115","author":"C Kenney","year":"2007","unstructured":"Kenney C, Jankovic J (2007) Botulinum toxin in the treatment of blepharospasm and hemifacial spasm. J Neural Transm 115(4):585\u2013591. https:\/\/doi.org\/10.1007\/S00702-007-0768-7","journal-title":"J Neural Transm"},{"key":"3070_CR5","doi-asserted-by":"crossref","first-page":"153","DOI":"10.3109\/01658109008997277","volume":"10","author":"JB Holds","year":"1990","unstructured":"Holds JB, Anderson RL, Jordan DR, Patrinely JR (1990) Bilateral hemifacial spasm. J Clin Neuroophthalmol 10:153\u2013154","journal-title":"J Clin Neuroophthalmol"},{"key":"3070_CR6","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1097\/WNO.0000000000000823","volume":"40","author":"MH Osaki","year":"2020","unstructured":"Osaki MH, Osaki TH, Osaki T et al (2020) Orbicularis oculi morphological alterations in affected and nonaffected sides in hemifacial spasm. J Neuroophthalmol 40:193\u2013197. https:\/\/doi.org\/10.1097\/WNO.0000000000000823","journal-title":"J Neuroophthalmol"},{"issue":"3","key":"3070_CR7","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1097\/WNO.0000000000001770","volume":"43","author":"TH Osaki","year":"2023","unstructured":"Osaki TH, Gameiro GR, Osaki MH et al (2023) Orbicularis oculi muscle immunohistochemical, metabolic and morphometric differences in affected and non-affected sides in hemifacial spasm versus healthy subjects. J Neuro-ophthalmol 43(3):410\u2013416","journal-title":"J Neuro-ophthalmol"},{"key":"3070_CR8","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1016\/J.JNS.2004.01.010","volume":"219","author":"EK Tan","year":"2004","unstructured":"Tan EK, Fook-Chong S, Lum SY, Lim E (2004) Botulinum toxin improves quality of life in hemifacial spasm: validation of a questionnaire (HFS-30). J Neurol Sci 219:151\u2013155. https:\/\/doi.org\/10.1016\/J.JNS.2004.01.010","journal-title":"J Neurol Sci"},{"key":"3070_CR9","doi-asserted-by":"publisher","first-page":"193","DOI":"10.3171\/2016.9.JNS161022","volume":"128","author":"JD Lawrence","year":"2017","unstructured":"Lawrence JD, Frederickson AM, Chang YF et al (2017) An investigation into quality of life improvement in patients undergoing microvascular decompression for hemifacial spasm. J Neurosurg 128:193\u2013201. https:\/\/doi.org\/10.3171\/2016.9.JNS161022","journal-title":"J Neurosurg"},{"key":"3070_CR10","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1590\/S0004-27492004000100008","volume":"67","author":"MH Osaki","year":"2004","unstructured":"Osaki MH, Belfort R (2004) Quality of life and direct cost regarding blepharospasm and hemifacial spasm patients treated with botulinum toxin A. Arq Bras Oftalmol 67:43\u201349. https:\/\/doi.org\/10.1590\/S0004-27492004000100008","journal-title":"Arq Bras Oftalmol"},{"key":"3070_CR11","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1097\/00002341-198601060-00005","volume":"2","author":"RS Gonnering","year":"1986","unstructured":"Gonnering RS (1986) Treatment of hemifacial spasm with botulinum a toxin: results and rationale. Ophthalmic Plast Reconstr Surg 2:143\u2013146. https:\/\/doi.org\/10.1097\/00002341-198601060-00005","journal-title":"Ophthalmic Plast Reconstr Surg"},{"issue":"8","key":"3070_CR12","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1007\/S00702-011-0762-Y","volume":"119","author":"B Wabbels","year":"2012","unstructured":"Wabbels B, Roggenk\u00e4mper P (2012) Botulinum toxin in hemifacial spasm: the challenge to assess the effect of treatment. J Neural Transm 119(8):963\u2013980. https:\/\/doi.org\/10.1007\/S00702-011-0762-Y","journal-title":"J Neural Transm"},{"key":"3070_CR13","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1111\/ENE.14258","volume":"27","author":"MH Osaki","year":"2020","unstructured":"Osaki MH, Osaki TH, Garcia DM et al (2020) An objective tool to measure the effect of botulinum toxin in blepharospasm and hemifacial spasm. Eur J Neurol 27:1487\u20131492. https:\/\/doi.org\/10.1111\/ENE.14258","journal-title":"Eur J Neurol"},{"key":"3070_CR14","unstructured":"Soukupova T, Cech J (2016) Eye blink detection using facial landmarks. In: 21st computer vision winter workshop, Rimske Toplice, Slovenia. p 2"},{"key":"3070_CR15","doi-asserted-by":"publisher","first-page":"e943","DOI":"10.7717\/PEERJ-CS.943","volume":"8","author":"C Dewi","year":"2022","unstructured":"Dewi C, Chen RC, Jiang X, Yu H (2022) Adjusting eye aspect ratio for strong eye blink detection based on facial landmarks. Peer J Comput Sci 8:e943. https:\/\/doi.org\/10.7717\/PEERJ-CS.943","journal-title":"Peer J Comput Sci"},{"key":"3070_CR16","doi-asserted-by":"publisher","first-page":"16","DOI":"10.3991\/IJIM.V14I14.14105","volume":"14","author":"C Huda","year":"2020","unstructured":"Huda C, Tolle H, Utaminingrum F (2020) Mobile-based driver sleepiness detection using facial landmarks and analysis of EAR values. Int J Interact Mobile Technol (iJIM) 14:16\u201330. https:\/\/doi.org\/10.3991\/IJIM.V14I14.14105","journal-title":"Int J Interact Mobile Technol (iJIM)"},{"key":"3070_CR17","doi-asserted-by":"publisher","unstructured":"Pandey NN, Muppalaneni NB (2021) Real-time drowsiness identification based on eye state analysis. In: Proceedings: International conference on artificial intelligence and smart systems, ICAIS pp 1182\u20131187. https:\/\/doi.org\/10.1109\/ICAIS50930.2021.9395975","DOI":"10.1109\/ICAIS50930.2021.9395975"},{"key":"3070_CR18","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/J.COGR.2022.01.003","volume":"2","author":"A Kuwahara","year":"2022","unstructured":"Kuwahara A, Nishikawa K, Hirakawa R et al (2022) Eye fatigue estimation using blink detection based on eye aspect ratio mapping(EARM). Cognit Robot 2:50\u201359. https:\/\/doi.org\/10.1016\/J.COGR.2022.01.003","journal-title":"Cognit Robot"},{"key":"3070_CR19","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/1038906","author":"J Feng","year":"2020","unstructured":"Feng J, Guo Z, Wang J, Dan G (2020) Using eye aspect ratio to enhance fast and objective assessment of facial paralysis. Comput Math Methods Med. https:\/\/doi.org\/10.1155\/2020\/1038906","journal-title":"Comput Math Methods Med"},{"key":"3070_CR20","doi-asserted-by":"publisher","unstructured":"Rakshita R (2018) Communication through Real-time video oculography using face landmark detection. In: proceedings of the international conference on inventive communication and computational technologies, ICICCT, pp 1094\u20131098. https:\/\/doi.org\/10.1109\/ICICCT.2018.8473269","DOI":"10.1109\/ICICCT.2018.8473269"},{"key":"3070_CR21","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1111\/ENE.15666","volume":"30","author":"C Yabumoto","year":"2023","unstructured":"Yabumoto C, Osaki MH, Gameiro GR et al (2023) Smartphone and custom-made software to assess the effect of botulinum toxin in essential blepharospasm: initial results. Eur J Neurol 30:887\u2013891. https:\/\/doi.org\/10.1111\/ENE.15666","journal-title":"Eur J Neurol"},{"issue":"9","key":"3070_CR22","doi-asserted-by":"publisher","first-page":"1887","DOI":"10.1007\/S10072-019-03921-4","volume":"40","author":"N Tambasco","year":"2019","unstructured":"Tambasco N, Simoni S, Sacchini E et al (2019) Validation of the hemifacial spasm grading scale: a clinical tool for hemifacial spasm. Neurol Sci 40(9):1887\u20131892. https:\/\/doi.org\/10.1007\/S10072-019-03921-4","journal-title":"Neurol Sci"},{"key":"3070_CR23","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1007\/s00702-020-02183-1","volume":"127","author":"TH Osaki","year":"2020","unstructured":"Osaki TH, Osaki MH, Garcia DM et al (2020) Evaluation of botulinum toxin effects in hemifacial spasm patients: correlation between clinical rating scales and high-speed video system measurements. J Neural Transm 127:1041\u20131046. https:\/\/doi.org\/10.1007\/s00702-020-02183-1","journal-title":"J Neural Transm"},{"key":"3070_CR24","doi-asserted-by":"publisher","first-page":"669","DOI":"10.1007\/s00417-019-04567-w","volume":"258","author":"MH Osaki","year":"2020","unstructured":"Osaki MH, Osaki TH, Garcia DM et al (2020) Analysis of blink activity and anomalous eyelid movements in patients with hemifacial spasm. Graefe\u2019s Arch Clin Exp Ophthalmol 258:669\u2013674. https:\/\/doi.org\/10.1007\/s00417-019-04567-w","journal-title":"Graefe\u2019s Arch Clin Exp Ophthalmol"},{"key":"3070_CR25","doi-asserted-by":"publisher","first-page":"1037","DOI":"10.2466\/pms.1999.88.3.1037","volume":"88","author":"K Kaneko","year":"1999","unstructured":"Kaneko K, Sakamoto K (1999) Evaluation of three types of blinks with the use of electro-oculogram and electromyogram. Percept Mot Skills 88:1037\u20131052. https:\/\/doi.org\/10.2466\/pms.1999.88.3.1037","journal-title":"Percept Mot Skills"},{"key":"3070_CR26","first-page":"387","volume":"32","author":"C Evinger","year":"1991","unstructured":"Evinger C, Manning K, Sibony PA (1991) Eyelid movements. Mechanisms and normal data. Invest Ophthalmol Vis Sci 32:387\u2013400","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"3070_CR27","doi-asserted-by":"publisher","first-page":"963","DOI":"10.1136\/bjophthalmol-2015-307272","volume":"100","author":"T Osaki","year":"2016","unstructured":"Osaki T, Osaki MH, Osaki TH et al (2016) Influence of involuntary eyelid spasms on corneal topographic and eyelid morphometric changes in patients with hemifacial spasm. Br J Ophthalmol 100:963. https:\/\/doi.org\/10.1136\/bjophthalmol-2015-307272","journal-title":"Br J Ophthalmol"},{"issue":"8","key":"3070_CR28","doi-asserted-by":"publisher","first-page":"1176","DOI":"10.1038\/s41591-020-0994-1","volume":"26","author":"S Gerke","year":"2020","unstructured":"Gerke S, Shachar C, Chai PR, Cohen IG (2020) Regulatory, safety, and privacy concerns of home monitoring technologies during COVID-19. Nat Med 26(8):1176\u20131182. https:\/\/doi.org\/10.1038\/s41591-020-0994-1","journal-title":"Nat Med"},{"key":"3070_CR29","doi-asserted-by":"publisher","DOI":"10.1016\/j.xops.2023.100342","author":"K Nagino","year":"2023","unstructured":"Nagino K, Sung J, Midorikawa-Inomata A et al (2023) Clinical utility of smartphone applications in ophthalmology: a systematic review. Ophthalmol Sci. https:\/\/doi.org\/10.1016\/j.xops.2023.100342","journal-title":"Ophthalmol Sci"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-024-03070-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-024-03070-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-024-03070-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T15:53:20Z","timestamp":1741881200000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-024-03070-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,18]]},"references-count":29,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024,12]]}},"alternative-id":["3070"],"URL":"https:\/\/doi.org\/10.1007\/s10792-024-03070-4","relation":{},"ISSN":["1573-2630"],"issn-type":[{"type":"electronic","value":"1573-2630"}],"subject":[],"published":{"date-parts":[[2024,3,18]]},"assertion":[{"value":"27 November 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 February 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interests"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Federal University of S\u00e3o Paulo (EPM\/UNIFESP) under number 0534\/2018.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"The authors state that human research participants provided informed consent for publication of the image in Fig.\u00a0, Fig.\u00a0 and Fig.\u00a0.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}],"article-number":"144"}}