{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T16:10:13Z","timestamp":1741882213627,"version":"3.38.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T00:00:00Z","timestamp":1713225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012681","name":"Universit\u00e4tsklinikum K\u00f6ln","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012681","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background\/Aims<\/jats:title>\n            <jats:p>This work aimed to investigate changes in optic nerve head (ONH) morphometry based on Bruch membrane opening in children with extensive nocturnal intraocular pressure (IOP) elevations.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>The course of Bruch membrane opening-based optic nerve head (ONH) morphometry was analysed in thirty-two patients younger than 18\u00a0years with evaluable SD-OCT examinations of the ONH and nocturnal posture-dependent IOP elevation above 25\u00a0mmHg. Longitudinal changes in neuroretinal rim tissue, as measured by Bruch Membrane opening minimum rim width (BMO-MRW) and peripapillary retinal nerve fiber layer (RNFL) thickness, were assessed.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>One year after the 24\u00a0h IOP measurement, global BMO-MRW (\u2212\u20091.61\u2009\u00b1\u200916.8\u00a0\u00b5m, n.s.; <jats:italic>p<\/jats:italic>\u2009=\u20090.611) and RNFL (+\u20090.64\u2009\u00b1\u20093.17\u00a0\u00b5m; n.s.; <jats:italic>p<\/jats:italic>\u2009=\u20090.292) measurements were not significantly different from the baseline. No significant BMO-MRW reduction (\u2212\u20093.91\u2009\u00b1\u200924.3\u00a0\u00b5m; n.s. <jats:italic>p<\/jats:italic>\u2009=\u20090.458) or deviation in RNFL thickness (+\u20091.10\u2009\u00b1\u20093.52\u00a0\u00b5m) was observed at the four-year follow-up. Absolute IOP values measured in the supine position did not correlate with changes in global BMO-MRW or RNFL thickness.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Posture-dependent IOP elevations do not seem to influence retinal nerve fibre layer thickness or Bruch membrane opening-based morphometric data in childhood.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10792-024-03109-6","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T06:01:56Z","timestamp":1713247316000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Susceptibility of optic nerve head in children with posture-related elevation of intraocular pressure"],"prefix":"10.1007","volume":"44","author":[{"given":"Jan Niklas","family":"L\u00fcke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline","family":"Gietzelt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Enders","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Dietlein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Lappa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"L\u00fcke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randolf Alexander","family":"Widder","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas S.","family":"Dietlein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"3109_CR1","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.survophthal.2009.12.002","volume":"55","author":"TS Prata","year":"2010","unstructured":"Prata TS, De Moraes CGV, Kanadani FN et al (2010) Posture-induced intraocular pressure changes: considerations regarding body position in glaucoma patients. 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