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Surgical success was defined according to six criteria, achieving a target intraocular pressure (IOP)\u2009\u2264\u200921, 18 or 15\u00a0mmHg on glaucoma medications (qualified success) or without any\u00a0further treatment (complete success), including laser therapy or surgery. Kaplan\u2013Meier survival analysis and Cox regression analysis were performed to evaluate surgical success and preoperative factors associated with surgical outcome. Surgical complications in the early postoperative period were compared between canaloplasty and phaco-canaloplasty.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Canaloplasty and phaco-canaloplasty significantly reduced postoperative IOP and number of glaucoma medications (<jats:italic>p<\/jats:italic>\u2009=\u20090.001 for both). Phaco-canaloplasty showed higher rates of cumulative surgical success over canaloplasty, but only for target IOP\u2009\u2264\u200921 and\u2009\u2264\u200918 (<jats:italic>p<\/jats:italic>\u2009=\u20090.018 and <jats:italic>p<\/jats:italic>\u2009=\u20090.011, respectively). A preoperative number of\u2009&gt;\u20094 glaucoma medications predicted surgical failure. Phaco-canaloplasty was associated with a higher rate of IOP peaks in the first month compared with canaloplasty (40.4% vs 12.7%, <jats:italic>p<\/jats:italic>\u2009=\u20090.000).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>Canaloplasty and phaco-canaloplasty demonstrated long-term efficacy in the treatment of open angle glaucoma, with phaco-canaloplasty showing higher rates of surgical success compared to canaloplasty, but not for target IOPs lower than 16\u00a0mmHg. Patients on more than 4 preoperative glaucoma medications may not be good\u00a0candidates for canaloplasty and may benefit from other surgical options.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s10792-024-03174-x","type":"journal-article","created":{"date-parts":[[2024,7,7]],"date-time":"2024-07-07T09:01:26Z","timestamp":1720342886000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Long-term outcomes of canaloplasty and phaco-canaloplasty in the treatment of open angle glaucoma: a single-surgeon experience"],"prefix":"10.1007","volume":"44","author":[{"given":"Daniele","family":"Tognetto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Cirigliano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Gouigoux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Grotto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pier Luigi","family":"Guerin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leandro","family":"Inferrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Marangoni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,7]]},"reference":[{"issue":"2","key":"3174_CR1","doi-asserted-by":"publisher","first-page":"e144","DOI":"10.1016\/S2214-109X(20)30489-7","volume":"9","author":"JD Steinmetz","year":"2021","unstructured":"Steinmetz JD, Bourne RRA, Briant PS et al (2021) Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the right to sight: an analysis for the global burden of disease study. 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