{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T05:25:43Z","timestamp":1781587543588,"version":"3.54.5"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T00:00:00Z","timestamp":1741910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Universit\u00e4tsklinikum Hamburg-Eppendorf (UKE)"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>This study aims to analyze the vision-related quality of life (vr-QoL) in keratoconus (KC) patients after corneal crosslinking (CXL).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A prospective clinical study was conducted, wherein 41 patients underwent assessment using the \"National Eye Institute Visual Functioning Questionnaire\" (NEI-25) and the \"Keratoconus Outcomes Research Questionnaire\" (KORQ) to evaluate vr-QoL, along with the examination of morphology and functional parameters before CXL, and at three and six months post-treatment. Rasch analyses were used to verify the measurement precision of the KORQ with our study population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>There were no statistically significant changes observed in corneal morphology and best corrected visual acuity after CXL. Analysis of the NEI-25 questionnaires and KORQ demonstrated no statistically significant changes throughout the follow-up period. Rasch analyses revealed a high measurement precision of the KORQ within our population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The study indicates that patients with progressive KC maintain stable vr-QoL after undergoing CXL. Based on our findings, we suggest considering very early CXL treatment for KC patients that are at high risk of progression.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10792-024-03400-6","type":"journal-article","created":{"date-parts":[[2025,3,14]],"date-time":"2025-03-14T08:57:49Z","timestamp":1741942669000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Quality of life in patients with progressive keratoconus treated with corneal collagen crosslinking"],"prefix":"10.1007","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3091-9347","authenticated-orcid":false,"given":"J.","family":"Steinberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Fischer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Frings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Druchkiv","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Katz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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