{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T18:09:06Z","timestamp":1766167746645,"version":"3.48.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T00:00:00Z","timestamp":1750723200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Rheon Medical SA"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The eyeWatch\u2122 implant is a novel glaucoma drainage device allowing for a titratable aqueous humour outflow via an external magnetic control unit, facilitating a more controlled reduction in intraocular pressure. We report on 12\u00a0month outcomes evaluating the safety and efficacy of eyeWatch\u2122 implant combined with an eyePlate (eyeWatch\u2122 system) in refractory glaucoma.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Prospective study including patients aged 18\u00a0years or older with refractory primary open angle, pigmentary or pseudoexfoliative glaucomas with elevated intraocular pressures\u2009&gt;\u200920\u00a0mmHg and previous failed filtration surgery were included. Patients underwent implantation of the eyeWatch\u2122 system. Outcomes were analysed post operatively on 1\u00a0day, 1\u00a0week, 2\u00a0week, 1\u00a0month, 2\u00a0months, 3\u00a0months, 6\u00a0months and 12\u00a0months after surgery. Main outcome measures were intraocular pressure reduction by\u2009\u2265\u200920% or intraocular pressure\u2009&lt;\u200921\u00a0mmHg and no intraocular pressure\u2009&lt;\u20096\u00a0mmHg on two consecutive visits after 12\u00a0months. Secondary outcomes were mean visual acuity, intraocular pressure and anti-glaucoma medications usage.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Twenty-seven patients were enrolled with a mean age of 68.9\u2009\u00b1\u20099.5\u00a0years. At 12\u00a0months, mean reduction of IOP was from 24.4\u2009\u00b1\u20095.2\u00a0mmHg at baseline to 13.2\u2009\u00b1\u20094.8\u00a0mmHg (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). The number of anti-glaucoma medications significantly decreased from 3.1\u2009\u00b1\u20090.7 (baseline) to 1.1\u2009\u00b1\u20091.1 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01). Visual acuity remained stable for almost all patients from 0.37\u2009\u00b1\u20090.32 to 0.39\u2009\u00b1\u20090.26 (logMAR). Complete success rate (intraocular pressure within defined range without glaucoma medications) was 47% and overall success rate was 93%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The eyeWatch\u2122 system allows for peri and postoperative non-invasive adjustments to resistance of aqueous humour outflow. At 12\u00a0months the majority of patients experienced adequate intraocular pressure control, with over 47% not requiring anti-glaucoma medications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10792-025-03573-8","type":"journal-article","created":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T01:19:50Z","timestamp":1750727990000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Short term clinical outcomes of the combined eyeWatch\u2122 implant and eyePlate in refractory glaucoma\u2014a United Kingdom dual centre study"],"prefix":"10.1007","volume":"45","author":[{"given":"Andrew J.","family":"Swampillai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leon","family":"Au","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kin Sheng","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,6,24]]},"reference":[{"key":"3573_CR1","doi-asserted-by":"crossref","unstructured":"Gedde SJ, Schiffman JC, Feuer WJ, Parrish RK 2nd, Heuer DK, Brandt JD, Tube Versus Trabeculectomy Study Group (2005) The tube versus trabeculectomy study: design and baseline characteristics of study patients. 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