{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T21:31:25Z","timestamp":1792704685131,"version":"4.5.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"DOI":"10.1007\/s10792-025-03746-5","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T04:57:11Z","timestamp":1759208231000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Culture positivity of anterior chamber exudate in cases of fungal keratitis"],"prefix":"10.1007","volume":"45","author":[{"given":"Amanjot","family":"Kaur","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smruti Rekha","family":"Priyadarshini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikant Kumar","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Himansu Sekhar","family":"Behera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujata","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"issue":"2","key":"3746_CR1","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1136\/bjophthalmol-2014-305000","volume":"99","author":"P Lalitha","year":"2015","unstructured":"Lalitha P, Prajna NV, Manoharan G et al (2015) Trends in bacterial and fungal keratitis in South India, 2002\u20132012. Br J Ophthalmol 99(2):192\u2013194","journal-title":"Br J Ophthalmol"},{"key":"3746_CR2","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1016\/B978-0-12-818731-9.00119-1","volume-title":"Encyclopedia of Infection and Immunity","author":"M Cabrera-Aguas","year":"2022","unstructured":"Cabrera-Aguas M, Khoo P, McCluskey P et al (2022) Fungal Ocular Infections. In: Rezaei N (ed) Encyclopedia of Infection and Immunity. Elsevier, pp 234\u2013245"},{"issue":"4","key":"3746_CR3","doi-asserted-by":"publisher","first-page":"321","DOI":"10.1097\/00055735-200408000-00008","volume":"15","author":"M Srinivasan","year":"2004","unstructured":"Srinivasan M (2004) Fungal keratitis. Curr Opin Ophthalmol 15(4):321\u2013327","journal-title":"Curr Opin Ophthalmol"},{"issue":"5","key":"3746_CR4","doi-asserted-by":"publisher","first-page":"543","DOI":"10.1111\/ceo.14113","volume":"50","author":"M Cabrera-Aguas","year":"2022","unstructured":"Cabrera-Aguas M, Khoo P, Watson SL (2022) Infectious keratitis: a review. Clin Exp Ophthalmol 50(5):543\u2013562","journal-title":"Clin Exp Ophthalmol"},{"key":"3746_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2020.108372","volume":"202","author":"B Mills","year":"2021","unstructured":"Mills B, Radhakrishnan N, Karthikeyan Rajapandian SG et al (2021) The role of fungi in fungal keratitis. Exp Eye Res 202:108372","journal-title":"Exp Eye Res"},{"issue":"11\u201312","key":"3746_CR6","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1007\/s11046-016-0042-3","volume":"181","author":"AK Ghosh","year":"2016","unstructured":"Ghosh AK, Gupta A, Rudramurthy SM et al (2016) Fungal keratitis in North India: spectrum of agents, risk factors and treatment. Mycopathologia 181(11\u201312):843\u2013850","journal-title":"Mycopathologia"},{"issue":"3","key":"3746_CR7","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1111\/1469-0691.12126","volume":"19","author":"PA Thomas","year":"2013","unstructured":"Thomas PA, Kaliamurthy J (2013) Mycotic keratitis: epidemiology, diagnosis and management. Clin Microbiol Infect 19(3):210\u2013220","journal-title":"Clin Microbiol Infect"},{"issue":"9","key":"3746_CR8","doi-asserted-by":"publisher","DOI":"10.3390\/jof8090962","volume":"8","author":"S Atta","year":"2022","unstructured":"Atta S, Perera C, Kowalski RP et al (2022) Fungal keratitis: clinical features, risk factors, treatment, and outcomes. J Fungi 8(9):962","journal-title":"J Fungi"},{"issue":"4","key":"3746_CR9","first-page":"315","volume":"51","author":"MJ Bharathi","year":"2003","unstructured":"Bharathi MJ, Ramakrishnan R, Vasu S et al (2003) Epidemiological characteristics and laboratory diagnosis of fungal keratitis. A three-year study. Indian J Ophthalmol 51(4):315\u2013321","journal-title":"Indian J Ophthalmol"},{"issue":"4","key":"3746_CR10","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1097\/ICO.0b013e318233f0a8","volume":"31","author":"V Mittal","year":"2012","unstructured":"Mittal V, Mittal R (2012) Intracameral and topical voriconazole for fungal corneal endoexudates. Cornea 31(4):366\u2013370","journal-title":"Cornea"},{"issue":"11","key":"3746_CR11","doi-asserted-by":"publisher","first-page":"877","DOI":"10.3109\/02713688609029240","volume":"5","author":"DM O'Day","year":"1986","unstructured":"O\u2019Day DM, Head WS, Robinson RD et al (1986) Corneal penetration of topical amphotericin B and natamycin. Curr Eye Res 5(11):877\u2013882","journal-title":"Curr Eye Res"},{"issue":"10","key":"3746_CR12","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.4103\/ijo.IJO_1952_18","volume":"67","author":"J Mundra","year":"2019","unstructured":"Mundra J, Dhakal R, Mohamed A et al (2019) Outcomes of therapeutic penetrating keratoplasty in 198 eyes with fungal keratitis. Indian J Ophthalmol 67(10):1599\u20131605","journal-title":"Indian J Ophthalmol"},{"issue":"12","key":"3746_CR13","volume":"13","author":"A Maniam","year":"2021","unstructured":"Maniam A, Chee Min L, Kiet Phang L et al (2021) Postoperative fungal keratitis managed by anterior chamber washout and intracameral amphotericin-B: a report of two cases. Cureus 13(12):e20769","journal-title":"Cureus"},{"issue":"4","key":"3746_CR14","first-page":"105","volume":"1","author":"R Jain","year":"2014","unstructured":"Jain R, Kapoor A, Virdi AS et al (2014) Role of evacuation of anterior chamber exudates as an adjunct in the management of deep fungal keratitis. Adv Ophthalmol Vis Syst 1(4):105\u2013110","journal-title":"Adv Ophthalmol Vis Syst"},{"issue":"12","key":"3746_CR15","doi-asserted-by":"publisher","first-page":"2011","DOI":"10.3390\/pharmaceutics13122011","volume":"13","author":"JH Hung","year":"2021","unstructured":"Hung JH, Lee CN, Hsu HW et al (2021) Recent advances in photodynamic therapy against fungal keratitis. Pharmaceutics 13(12):2011","journal-title":"Pharmaceutics"},{"issue":"1","key":"3746_CR16","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1016\/j.ajo.2008.02.023","volume":"146","author":"G Prakash","year":"2008","unstructured":"Prakash G, Sharma N, Goel M et al (2008) Evaluation of intrastromal injection of voriconazole as a therapeutic adjunctive for the management of deep recalcitrant fungal keratitis. Am J Ophthalmol 146(1):56\u201359","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"3746_CR17","first-page":"470","volume":"125","author":"LJ Xu","year":"2012","unstructured":"Xu LJ, Song XS, Zhao J et al (2012) Hypopyon in patients with fungal keratitis. Chin Med J (Engl) 125(3):470\u2013475","journal-title":"Chin Med J (Engl)"},{"issue":"11","key":"3746_CR18","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.3109\/02713683.2012.698357","volume":"37","author":"KG Eleinen","year":"2012","unstructured":"Eleinen KG, Mohalhal AA, Elmekawy HE et al (2012) Polymerase chain reaction-guided diagnosis of infective keratitis - a hospital-based study. Curr Eye Res 37(11):1005\u20131011","journal-title":"Curr Eye Res"},{"issue":"1","key":"3746_CR19","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1007\/s12348-011-0019-9","volume":"1","author":"C Ferrer","year":"2011","unstructured":"Ferrer C, Ali\u00f3 JL (2011) Evaluation of molecular diagnosis in fungal keratitis. Ten years of experience. J Ophthalmic Inflamm Infect 1(1):15\u201322","journal-title":"J Ophthalmic Inflamm Infect"},{"issue":"1","key":"3746_CR20","doi-asserted-by":"publisher","first-page":"35","DOI":"10.4103\/ijo.IJO_378_19","volume":"68","author":"P Konar","year":"2020","unstructured":"Konar P, Joshi S, Mandhare SJ et al (2020) Intrastromal voriconazole: an adjuvant approach for recalcitrant mycotic keratitis. Indian J Ophthalmol 68(1):35\u201338","journal-title":"Indian J Ophthalmol"},{"key":"3746_CR21","doi-asserted-by":"crossref","unstructured":"Prajna NV, Krishnan T, Mascarenhas J, et al. Mycotic Ulcer Treatment Trial Group.2013 The mycotic ulcer treatment trial: a randomized trial comparing natamycin vs voriconazole. JAMA Ophthalmol, 131(4):422\u2013429","DOI":"10.1001\/jamaophthalmol.2013.1497"},{"issue":"8","key":"3746_CR22","doi-asserted-by":"publisher","first-page":"1538","DOI":"10.1016\/S0161-6420(02)01088-6","volume":"109","author":"GK Vemuganti","year":"2002","unstructured":"Vemuganti GK, Garg P, Gopinathan U et al (2002) Evaluation of agent and host factors in progression of mycotic keratitis: a histologic and microbiologic study of 167 corneal buttons. Ophthalmology 109(8):1538\u20131546","journal-title":"Ophthalmology"},{"key":"3746_CR23","doi-asserted-by":"crossref","unstructured":"Gong Y, Xin M (2019) Incidence of recurrent fungal keratitis after primary keratoplasty and visual outcome and prognosis after intervention for the recurrence. Medicine (Baltimore) 98(24):e15910","DOI":"10.1097\/MD.0000000000015910"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-025-03746-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-025-03746-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-025-03746-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T18:03:45Z","timestamp":1766167425000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-025-03746-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":23,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["3746"],"URL":"https:\/\/doi.org\/10.1007\/s10792-025-03746-5","relation":{},"ISSN":["1573-2630"],"issn-type":[{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]},"assertion":[{"value":"25 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Institution Ethics Committee, L V Prasad Eye Institute, Bhubaneswar, Odisha, India. ID# 2019-007-BHR-29.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"399"}}