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We included 196 patients (197 eyes) undergoing PhV. Electronic medical records provided baseline patient data, data on indication for vitrectomy, surgery data including intra-ocular lens (IOL) type, complications, and YAG-CT incidence during 6-year follow-up after PhV. Univariate and multivariate regression analyses assessed associations of various factors with YAG-CT incidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Fifty-four eyes (27.41%) underwent YAG-CT during the follow-up period. One of the three hydrophilic acrylic IOLs showed the lowest YAG-CT incidence. Adjusted Odds Ratios (aORs) for YAG-CT were significantly higher for the hydrophobic acrylic IOL (aOR\u2009=\u20095.85,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.05), and the two other hydrophilic acrylic IOLs (aOR\u2009=\u200929.0,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001 and aOR\u2009=\u200979.4,\n                      <jats:italic>p\u2009<\/jats:italic>\n                      &lt;\u20090.001). Compared with PhV for macular hole, PhV for epiretinal membranes (aOR\u2009=\u20099.9,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), retinal detachment (aOR\u2009=\u200925.4,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01), and silicon oil removal (aOR\u2009=\u200922.4,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05) correlated with higher YAG-CT incidence. Type 2 diabetes correlated with increased YAG-CT incidence (aOR\u2009=\u20096.7,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>IOL type is a key factor in development of visually disturbing PCO after phacovitrectomy. One hydrophilic acrylic IOL outperformed other examined IOLs in reducing YAG-CT incidence after PhV. Retinal disease, as well as type 2 diabetes, correlated with YAG-CT, and should motivate a choice of an IOL type associated with a low YAG-CT incidence for PhV.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10792-026-04017-7","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T11:41:25Z","timestamp":1773229285000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Risk factors for posterior capsule opacification following phacovitrectomy: a six-year retrospective analysis"],"prefix":"10.1007","volume":"46","author":[{"given":"Mieszko","family":"Lachota","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agata","family":"Frajdenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karolina Radl","family":"Steiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wojciech","family":"Hautz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjorn","family":"Johansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcin Piotr","family":"Czajka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,11]]},"reference":[{"key":"4017_CR1","doi-asserted-by":"crossref","unstructured":"Villegas VM, Gold AS, Latiff A, Wildner AC, Ehlies FJ, Murray TG Phacovitrectomy (2014) Aug 27 [cited 2023 July 12]; Available from: https:\/\/karger.com\/books\/book\/176\/chapter\/5113698\/Phacovitrectomy","DOI":"10.1159\/000360455"},{"issue":"1","key":"4017_CR2","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s40123-017-0084-8","volume":"6","author":"A Mercanti","year":"2017","unstructured":"Mercanti A, Renna A (2017) A review of microinvasive combined phaco-vitrectomy: recent Technical advances. 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Mieszko Lachota is a speaker for TACTICA Pharmaceuticals and Pharmaceutical Works Polpharma. Other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The Regional Ethical Review Board in Link\u00f6ping approved the study protocol (registration number M52-08). The study protocol did not require that each patient provide written informed consent.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}],"article-number":"152"}}