{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T14:15:58Z","timestamp":1789049758388,"version":"build-2803163510"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:00:00Z","timestamp":1788998400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Int Ophthalmol"],"DOI":"10.1007\/s10792-026-04253-x","type":"journal-article","created":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:54:42Z","timestamp":1789048482000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Anterior segment OCT-based assessment of efficacy of topical cyclosporine in edematous punctal stenosis"],"prefix":"10.1007","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4463-1413","authenticated-orcid":false,"given":"Hilal Nalc\u0131","family":"Baytaro\u011flu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3352-9547","authenticated-orcid":false,"given":"Kubra Ozdemir","family":"Yalcinsoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,10]]},"reference":[{"key":"4253_CR1","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/j.survophthal.2024.02.001","volume":"69","author":"HA Tawfik","year":"2024","unstructured":"Tawfik HA, Ali MJ (2024) A major review of punctal stenosis: updated anatomy, epidemiology, etiology, and clinical presentation. Surv Ophthalmol 69:441\u2013455. https:\/\/doi.org\/10.1016\/j.survophthal.2024.02.001","journal-title":"Surv Ophthalmol"},{"key":"4253_CR2","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1097\/iop.0000000000001064","volume":"34","author":"MJ Ali","year":"2018","unstructured":"Ali MJ (2018) Idiopathic canalicular inflammatory disease: new disease description of clinical patterns, investigations, management, and outcomes. Ophthalmic Plast Reconstr Surg 34:528\u2013532. https:\/\/doi.org\/10.1097\/iop.0000000000001064","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"4253_CR3","doi-asserted-by":"publisher","first-page":"1981","DOI":"10.1007\/s10792-018-1031-y","volume":"39","author":"T Kornhauser","year":"2019","unstructured":"Kornhauser T, Segal A, Walter E et al (2019) Idiopathic edematous punctal stenosis with chronic epiphora: preponderance in young women. Int Ophthalmol 39:1981\u20131986. https:\/\/doi.org\/10.1007\/s10792-018-1031-y","journal-title":"Int Ophthalmol"},{"key":"4253_CR4","doi-asserted-by":"publisher","first-page":"7988091","DOI":"10.1155\/2022\/7988091","volume":"2022","author":"I Awny","year":"2022","unstructured":"Awny I, Mossa EAM, Bakheet TM et al (2022) Changes of lacrimal puncta by anterior segment optical coherence tomography after topical combined antibiotic and steroid treatment in cases of inflammatory punctual stenosis. J Ophthalmol 2022:7988091. https:\/\/doi.org\/10.1155\/2022\/7988091","journal-title":"J Ophthalmol"},{"key":"4253_CR5","doi-asserted-by":"publisher","first-page":"7666323","DOI":"10.1155\/2022\/7666323","volume":"2022","author":"I Awny","year":"2022","unstructured":"Awny I, Mossa EAM, Bakheet TM et al (2022) Evaluation of lacrimal punctal changes by anterior segment optical coherence tomography after punctal dilation versus punctal plug insertion in cases of inflammatory punctual stenosis. J Ophthalmol 2022:7666323. https:\/\/doi.org\/10.1155\/2022\/7666323","journal-title":"J Ophthalmol"},{"key":"4253_CR6","doi-asserted-by":"publisher","first-page":"1074","DOI":"10.18240\/ijo.2020.07.09","volume":"13","author":"HY Elalfy","year":"2020","unstructured":"Elalfy HY, Elsamkary MA, Elridy AMS et al (2020) Medical treatment of inflammatory punctual stenosis monitored by anterior segment optical coherence tomography. Int J Ophthalmol 13:1074\u20131078. https:\/\/doi.org\/10.18240\/ijo.2020.07.09","journal-title":"Int J Ophthalmol"},{"key":"4253_CR7","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1016\/j.survophthal.2024.05.007","volume":"69","author":"HA Tawfik","year":"2024","unstructured":"Tawfik HA, Ali MJ (2024) A major review on punctal stenosis: Part II: updated therapeutic interventions, complications, and outcomes. Surv Ophthalmol 69:756\u2013768. https:\/\/doi.org\/10.1016\/j.survophthal.2024.05.007","journal-title":"Surv Ophthalmol"},{"key":"4253_CR8","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1177\/112067210801800401","volume":"18","author":"MB Kashkouli","year":"2008","unstructured":"Kashkouli MB, Nilforushan N, Nojomi N et al (2008) External lacrimal punctum grading: reliability and interobserver variation. Eur J Ophthalmol 18:507\u2013511. https:\/\/doi.org\/10.1177\/112067210801800401","journal-title":"Eur J Ophthalmol"},{"key":"4253_CR9","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1148\/radiology.177.3.2243969","volume":"177","author":"PL Munk","year":"1990","unstructured":"Munk PL, Lin DT, Morris DC (1990) Epiphora: treatment by means of dacryocystoplasty with balloon dilation of the nasolacrimal drainage apparatus. Radiology 177:687\u2013690. https:\/\/doi.org\/10.1148\/radiology.177.3.2243969","journal-title":"Radiology"},{"key":"4253_CR10","doi-asserted-by":"publisher","first-page":"124","DOI":"10.4103\/joco.Joco_131_20","volume":"33","author":"A Sabermoghaddam","year":"2021","unstructured":"Sabermoghaddam A, Golestani S, Hassanpour K et al (2021) Investigation of the lower punctum parameters: a spectral domain anterior segment optical coherence tomography study. J Curr Ophthalmol 33:124\u2013127. https:\/\/doi.org\/10.4103\/joco.Joco_131_20","journal-title":"J Curr Ophthalmol"},{"key":"4253_CR11","doi-asserted-by":"publisher","first-page":"e619","DOI":"10.1111\/aos.13322","volume":"95","author":"Y Sung","year":"2017","unstructured":"Sung Y, Park JS, Lew H (2017) Measurement of lacrimal punctum using spectralis domain anterior optical coherence tomography. Acta Ophthalmol 95:e619\u2013e624. https:\/\/doi.org\/10.1111\/aos.13322","journal-title":"Acta Ophthalmol"},{"key":"4253_CR12","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1097\/iop.0000000000001840","volume":"37","author":"Y Bian","year":"2021","unstructured":"Bian Y, Scofield-Kaplan SM, Zemsky C et al (2021) Punctal congestion syndrome: a reversible, functional punctal stenosis causing epiphora in the setting of chronic pretarsal conjunctivitis. Ophthalmic Plast Reconstr Surg 37:92\u201397. https:\/\/doi.org\/10.1097\/iop.0000000000001840","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"4253_CR13","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1097\/iop.0000000000000204","volume":"31","author":"MJ Ali","year":"2015","unstructured":"Ali MJ, Mishra DK, Baig F et al (2015) Punctal stenosis: histopathology, immunology, and electron microscopic features-a step toward unraveling the mysterious etiopathogenesis. Ophthalmic Plast Reconstr Surg 31:98\u2013102. https:\/\/doi.org\/10.1097\/iop.0000000000000204","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"4253_CR14","doi-asserted-by":"publisher","DOI":"10.1080\/08820538.2024.2345279","author":"YL Barzelay","year":"2024","unstructured":"Barzelay YL, Carmon D, Dagan M et al (2024) Association between acquired punctal stenosis and ocular surface disease: the egg and the chicken story. Semin Ophthalmol. https:\/\/doi.org\/10.1080\/08820538.2024.2345279","journal-title":"Semin Ophthalmol"},{"key":"4253_CR15","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1136\/bjo.82.6.666","volume":"82","author":"P Prabhasawat","year":"1998","unstructured":"Prabhasawat P, Tseng SC (1998) Frequent association of delayed tear clearance in ocular irritation. Br J Ophthalmol 82:666\u2013675. https:\/\/doi.org\/10.1136\/bjo.82.6.666","journal-title":"Br J Ophthalmol"},{"key":"4253_CR16","doi-asserted-by":"publisher","first-page":"1467","DOI":"10.2147\/opth.S255979","volume":"14","author":"MS Elshorbagy","year":"2020","unstructured":"Elshorbagy MS, Shalaby OE, Eldesouky MA et al (2020) Anterior segment optical coherence tomography (AS-OCT) guided reversal of edematous punctal occlusion. Clin Ophthalmol 14:1467\u20131472. https:\/\/doi.org\/10.2147\/opth.S255979","journal-title":"Clin Ophthalmol"},{"key":"4253_CR17","doi-asserted-by":"publisher","DOI":"10.1080\/08820538.2512759","author":"B Mariya","year":"2025","unstructured":"Mariya B, Kate A, Tallapelly HG et al (2025) The role of topical cyclosporine a in ocular surface inflammatory disorders. Semin Ophthalmol. https:\/\/doi.org\/10.1080\/08820538.2512759","journal-title":"Semin Ophthalmol"},{"key":"4253_CR18","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1097\/iop.0000000000001672","volume":"37","author":"MJ Ali","year":"2021","unstructured":"Ali MJ, Bothra N (2021) Update on idiopathic canalicular inflammatory disease (ICID): outcomes with addition of topical cyclosporine and the modified treatment protocol. Ophthalmic Plast Reconstr Surg 37:38\u201341. https:\/\/doi.org\/10.1097\/iop.0000000000001672","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"4253_CR19","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1080\/01676830.2023.2232028","volume":"43","author":"M Nassief","year":"2024","unstructured":"Nassief M, Lotfy NM (2024) Topical cyclosporin A 0.05% eye drops for management of symptomatic acquired punctal stenosis: a prospective, controlled clinical study. Orbit 43:190\u2013195. https:\/\/doi.org\/10.1080\/01676830.2023.2232028","journal-title":"Orbit"},{"key":"4253_CR20","doi-asserted-by":"publisher","first-page":"103234","DOI":"10.1016\/j.pdpdt.2022.103234","volume":"41","author":"KS Ceylanoglu","year":"2023","unstructured":"Ceylanoglu KS, Sen EM (2023) The effect of topical steroids and non-steroidal anti inflammatory drugs on epiphora of unknown cause: optical coherence tomography study. Photodiagnosis Photodyn Ther 41:103234. https:\/\/doi.org\/10.1016\/j.pdpdt.2022.103234","journal-title":"Photodiagnosis Photodyn Ther"}],"container-title":["International Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-026-04253-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s10792-026-04253-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s10792-026-04253-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T13:54:43Z","timestamp":1789048483000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s10792-026-04253-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,10]]},"references-count":20,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["4253"],"URL":"https:\/\/doi.org\/10.1007\/s10792-026-04253-x","relation":{},"ISSN":["1573-2630"],"issn-type":[{"value":"1573-2630","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,10]]},"assertion":[{"value":"15 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors have no relevant financial or non-financial interests to disclose.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"390"}}