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Participants underwent ophthalmologic examination and serological testing for anti-\n                      <jats:italic>T. gondii<\/jats:italic>\n                      \u00a0IgG and IgM antibodies. Patients were classified into control (G1), active lesion (G2), and cicatricial lesion (G3) groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 76.5% of patients were positive for anti-\n                      <jats:italic>T. gondii<\/jats:italic>\n                      IgG, while 3.5% were positive for IgM. Most patients with cicatricial lesions (G3) were IgG-positive (31\/33). In contrast, IgM positivity was restricted to a small subset of patients (3\/13) with active lesions (G2). Ophthalmologic evaluation demonstrated that unilateral disease predominated (78.2%), with lesions mainly located in the posterior pole (52.8%). Morphologically, round-to-ovoid lesions were most frequent (60.0%), followed by amoeboid (16.0%), placoid (8.0%), and wedge-shaped and punctate (4.0% each) patterns. Mean lesion size among evaluable eyes was 16.2\u00a0mm\n                      <jats:sup>2<\/jats:sup>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The analyses provide data that contribute to the understanding of the clinical characteristics of the disease, ocular behavior, and serological findings. Consequently, preventive measures may be implemented, reducing risk factors and improving patients\u2019 quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s10792-026-04302-5","type":"journal-article","created":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T12:07:07Z","timestamp":1792238827000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical and imaging characterization of ocular toxoplasmosis in a Central-West Brazilian population"],"prefix":"10.1007","volume":"46","author":[{"given":"Alexsandra Passarelli Giabardo","family":"Marques","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiza Roschel","family":"Zaunrith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danilo Donizete","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aparecida Perp\u00e9tuo","family":"Silveira Carvalho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando Henrique Antunes","family":"Murata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rubens Camargo","family":"Siqueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Gazarini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edis","family":"Belini J\u00fanior","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie Massayo Maeda","family":"Oda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christiane Maria","family":"Ayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Carlos","family":"de Mattos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4836-3113","authenticated-orcid":false,"given":"Cinara C\u00e1ssia","family":"Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,17]]},"reference":[{"key":"4302_CR1","volume-title":"Toxoplasmosis of animals and humans","author":"JP Dubey","year":"2022","unstructured":"Dubey JP (2022) Toxoplasmosis of animals and humans, 3rd ed. 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