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Our primary aim was to investigate whether females with CD show empathy deficits when using a more ecologically-valid task. We used an empathic accuracy (EA) paradigm that involved watching videos of actors recalling emotional experiences and providing continuous ratings of emotional intensity (assessing EA), naming the emotion expressed (emotion recognition), and reporting whether they shared the emotion expressed (affective empathy). We compared 23 females with CD and 29 typically-developing (TD) adolescents aged 13\u201318\u00a0years. The CD sample was divided into subgroups with higher (CD\/CU+) versus lower (CD\/CU\u2212) levels of callous-unemotional traits. Females with CD did not differ from TD females in EA or emotion recognition but exhibited reduced affective empathy responses (<jats:italic>p<\/jats:italic>s\u2009&lt;\u00a00.01, <jats:italic>r<\/jats:italic>s\u2009\u2265\u00a00.39). The CD\/CU+ and CD\/CU\u2212 subgroups did not differ on any empathy measure. We also assessed for sex differences in CD-empathy associations by comparing the present data with archive data from males. CD adolescents exhibited impairments in EA relative to their TD counterparts overall (<jats:italic>p<\/jats:italic>\u00a0&lt;\u00a00.05, \u03b7p<jats:sup>2<\/jats:sup>\u00a0=\u00a00.06), but there was no sex-by-diagnosis interaction. While females with CD were only impaired in affective empathy, males with CD exhibited emotion recognition and affective empathy deficits. This study demonstrates that females with CD show relatively specific impairments in affective empathy on an ecologically-valid task, whereas males with CD display more global empathic difficulties.<\/jats:p>","DOI":"10.1007\/s10802-020-00659-y","type":"journal-article","created":{"date-parts":[[2020,6,2]],"date-time":"2020-06-02T07:04:36Z","timestamp":1591081476000},"page":"1155-1167","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Empathic Accuracy in Female Adolescents with Conduct Disorder and Sex Differences in the Relationship Between Conduct Disorder and Empathy"],"prefix":"10.1007","volume":"48","author":[{"given":"N. 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